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The map label for this gene is fabA

Identifier: 119774742

GI number: 119774742

Start: 1961420

End: 1961935

Strand: Reverse

Name: fabA

Synonym: Sama_1605

Alternate gene names: 119774742

Gene position: 1961935-1961420 (Counterclockwise)

Preceding gene: 119774743

Following gene: 119774718

Centisome position: 45.56

GC content: 52.52

Gene sequence:

>516_bases
ATGACTAAAGCAAACAGCTACACCAAAGAAGAACTGATCGCCTGTGGCCATGGCGAGCTTCTTGGCAAAAATTCTCCCCG
TCTGCCCGTAGACAACATGCTGATGATCGATCGCGTCGTAACCATTAACGACAATGGCGGCACCTTCGGCAAAGGAGAAA
TCGTAGCAGAGCTGGATATTGATCCGGATCTCTGGTTCTTTGGTTGCCACTTCGTAGAAGACCCCGTAATGCCAGGTTGT
CTTGGCCTCGATGCCATGTGGCAGCTGGTCGGCTTCTTCCTTGCGTGGGAAGGGGCTCAGGGCAAAGGTCGTGCACTGGG
TGTAGGTGAAGTGAAATTTACCGGTCAGGTACTGCCAGGTGCCAAGAAAGTCACTTACAAGCTCAACATCAAGCGCACCA
TCCACCGCAAGCTGGTGATGGGTATTGCCGATGCGACCCTGGAAGTGGACGGTCGTGAAATCTATTCCGCCACCGATTTG
AAAGTGGGCGTGTTTACTGACACCTCTACCTTCTGA

Upstream 100 bases:

>100_bases
ATGGCCATTTTCCAGAGCCTAAATCGGTGGTTGGACTTGTTTGGCGTACAGGTGTTCGCTAATCTTTGGCACTCTTAATG
ATGGAGTGGTAACTATTACA

Downstream 100 bases:

>100_bases
TAAAGACCATAATCAAAAACACCGGCTAAGGCCGGTGTTTTTGTTTGTATCTGCAGGTATCTGCTTTACAGGGCTAAACG
CATCTATTGCTTCTAAAAAG

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MTKANSYTKEELIACGHGELLGKNSPRLPVDNMLMIDRVVTINDNGGTFGKGEIVAELDIDPDLWFFGCHFVEDPVMPGC
LGLDAMWQLVGFFLAWEGAQGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADATLEVDGREIYSATDL
KVGVFTDTSTF

Sequences:

>Translated_171_residues
MTKANSYTKEELIACGHGELLGKNSPRLPVDNMLMIDRVVTINDNGGTFGKGEIVAELDIDPDLWFFGCHFVEDPVMPGC
LGLDAMWQLVGFFLAWEGAQGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADATLEVDGREIYSATDL
KVGVFTDTSTF
>Mature_170_residues
TKANSYTKEELIACGHGELLGKNSPRLPVDNMLMIDRVVTINDNGGTFGKGEIVAELDIDPDLWFFGCHFVEDPVMPGCL
GLDAMWQLVGFFLAWEGAQGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADATLEVDGREIYSATDLK
VGVFTDTSTF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily

Homologues:

Organism=Escherichia coli, GI1787187, Length=169, Percent_Identity=68.6390532544379, Blast_Score=251, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABA_SHEAM (A1S606)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927482.1
- ProteinModelPortal:   A1S606
- SMR:   A1S606
- STRING:   A1S606
- GeneID:   4603857
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1605
- NMPDR:   fig|326297.7.peg.1516
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   CHFKGDP
- ProtClustDB:   PRK05174
- GO:   GO:0005737
- HAMAP:   MF_00405
- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114
- PANTHER:   PTHR11712
- TIGRFAMs:   TIGR01749

Pfam domain/function: PF07977 FabA

EC number: =4.2.1.60

Molecular weight: Translated: 18669; Mature: 18538

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: ACT_SITE 70-70

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKANSYTKEELIACGHGELLGKNSPRLPVDNMLMIDRVVTINDNGGTFGKGEIVAELDI
CCCCCCCCHHHHEECCCCCEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
DPDLWFFGCHFVEDPVMPGCLGLDAMWQLVGFFLAWEGAQGKGRALGVGEVKFTGQVLPG
CCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCEEECCEEEEECEECCC
AKKVTYKLNIKRTIHRKLVMGIADATLEVDGREIYSATDLKVGVFTDTSTF
CEEEEEEEECHHHHHHHHHHHHCCCEEEECCCEEEEECCEEEEEEECCCCC
>Mature Secondary Structure 
TKANSYTKEELIACGHGELLGKNSPRLPVDNMLMIDRVVTINDNGGTFGKGEIVAELDI
CCCCCCCHHHHEECCCCCEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
DPDLWFFGCHFVEDPVMPGCLGLDAMWQLVGFFLAWEGAQGKGRALGVGEVKFTGQVLPG
CCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCEEECCEEEEECEECCC
AKKVTYKLNIKRTIHRKLVMGIADATLEVDGREIYSATDLKVGVFTDTSTF
CEEEEEEEECHHHHHHHHHHHHCCCEEEECCCEEEEECCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA