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The map label for this gene is ackA

Identifier: 119774632

GI number: 119774632

Start: 1809919

End: 1811118

Strand: Reverse

Name: ackA

Synonym: Sama_1495

Alternate gene names: 119774632

Gene position: 1811118-1809919 (Counterclockwise)

Preceding gene: 119774634

Following gene: 119774631

Centisome position: 42.06

GC content: 53.67

Gene sequence:

>1200_bases
ATGTCCAATACTTTGGTTCTGGTACTCAACTGTGGCAGTTCTTCACTGAAGTTTGCCATTCTGGACGCCACCAATGGCGA
CGAAAAAATTTCCGGTTTGGCCGAGTGCTTTGGTCTGGAAAATGCCCGCATCAAGTGGAAATTACGCGGCGAGAAACACG
AAGCCAGTTTGGGCGCCTTCAGCGCTCACCGCGAAGCGGTGGAATACATAGTCAACAAAATTCTGGTGAATGAGCCTGAA
CTGAAAGGCCAACTTATCGCCATTGGCCACCGTATCGTGCACGGCGGAGAAAAGTTCACCCACTCCGTCATTATCGATGA
TGCCGTACTCAAGGGTATCGAAGACTGTGCCTCGCTGGCGCCACTCCATAACCCTGCGCACCTTATCGGTATTCGTGCGG
CCCAGGCCTCTTTCCCGTCGCTGCCTCAAGTTGCCGTGTTCGATACCGCCTTCCACCAGAGTATGCCAGACCGGGCCTAT
ATCTATGCCCTGCCCTACAAGCTCTATCGTGAGCACGGTATCCGCCGCTACGGCATGCACGGTACCAGCCACTTGTTCGT
AAGCCGTGAAGCCGCCAAGGCCCTAGGCAAAGACGTGAACGACACCAATGTGATTTGTGCCCATCTGGGTAACGGTGCCT
CTGTAACGGCAGTGAAAGGCGGCAAGAGTGTAGACACCTCTATGGGTCTGACCCCGCTGGAAGGTCTGGTAATGGGAACT
CGCTGTGGCGATCTGGATCCCTCCATCATCTACCACCTGGTGCATCAGCTGGGTTACACCCTGGATGAAGTGAACAACCT
GATGAACAAACAGAGTGGTTTGCTCGGTATTTCTGAGCTCACCAACGATTGTCGCGGTATCGAAGAAGGCTACGCCGAAG
GCCACAAGGGTGCGACTCTGGCATTGGAGATCTTCTGCTACCGTCTGGCCAAATACATCGCCTCCTATACAGTGCCACTG
GGCCGTCTGGATGCCATCGTATTCACCGGCGGCATCGGCGAAAACTCTGACCTTATCCGTGAAAAGGTTTTGAATCTGCT
TGAAATCTTTAAGTTTGAAGTTGACAGCGAGCGCAATAAGGCAGCCCGCTTCGGTAACCAGGGCGTGATTACCAAAGAGG
GCAGTCCCATTGCCATGGTGATCCCCACCAACGAAGAGTGGGTCATCGCCGAAGACTCGCTGCGTCTGGTTAACAAATAA

Upstream 100 bases:

>100_bases
GCTCAGGGAAGCAGATGAGAAGTTTTAATGGCCTGCCCGCCAGGCAAAGTCGCCGGAGCAAGACCCGGCCAACTATTTCA
TGACGCAAGAAGGTTTTATC

Downstream 100 bases:

>100_bases
GGCGCCCGCCGCCCCGGGACTCCCGCGGGCGGATTTGCATTAAAAGCATCTGATGGCCCGACCATCAAAGCAACACCCTA
AGAGGTACTTTATGTCCCGC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSNTLVLVLNCGSSSLKFAILDATNGDEKISGLAECFGLENARIKWKLRGEKHEASLGAFSAHREAVEYIVNKILVNEPE
LKGQLIAIGHRIVHGGEKFTHSVIIDDAVLKGIEDCASLAPLHNPAHLIGIRAAQASFPSLPQVAVFDTAFHQSMPDRAY
IYALPYKLYREHGIRRYGMHGTSHLFVSREAAKALGKDVNDTNVICAHLGNGASVTAVKGGKSVDTSMGLTPLEGLVMGT
RCGDLDPSIIYHLVHQLGYTLDEVNNLMNKQSGLLGISELTNDCRGIEEGYAEGHKGATLALEIFCYRLAKYIASYTVPL
GRLDAIVFTGGIGENSDLIREKVLNLLEIFKFEVDSERNKAARFGNQGVITKEGSPIAMVIPTNEEWVIAEDSLRLVNK

Sequences:

>Translated_399_residues
MSNTLVLVLNCGSSSLKFAILDATNGDEKISGLAECFGLENARIKWKLRGEKHEASLGAFSAHREAVEYIVNKILVNEPE
LKGQLIAIGHRIVHGGEKFTHSVIIDDAVLKGIEDCASLAPLHNPAHLIGIRAAQASFPSLPQVAVFDTAFHQSMPDRAY
IYALPYKLYREHGIRRYGMHGTSHLFVSREAAKALGKDVNDTNVICAHLGNGASVTAVKGGKSVDTSMGLTPLEGLVMGT
RCGDLDPSIIYHLVHQLGYTLDEVNNLMNKQSGLLGISELTNDCRGIEEGYAEGHKGATLALEIFCYRLAKYIASYTVPL
GRLDAIVFTGGIGENSDLIREKVLNLLEIFKFEVDSERNKAARFGNQGVITKEGSPIAMVIPTNEEWVIAEDSLRLVNK
>Mature_398_residues
SNTLVLVLNCGSSSLKFAILDATNGDEKISGLAECFGLENARIKWKLRGEKHEASLGAFSAHREAVEYIVNKILVNEPEL
KGQLIAIGHRIVHGGEKFTHSVIIDDAVLKGIEDCASLAPLHNPAHLIGIRAAQASFPSLPQVAVFDTAFHQSMPDRAYI
YALPYKLYREHGIRRYGMHGTSHLFVSREAAKALGKDVNDTNVICAHLGNGASVTAVKGGKSVDTSMGLTPLEGLVMGTR
CGDLDPSIIYHLVHQLGYTLDEVNNLMNKQSGLLGISELTNDCRGIEEGYAEGHKGATLALEIFCYRLAKYIASYTVPLG
RLDAIVFTGGIGENSDLIREKVLNLLEIFKFEVDSERNKAARFGNQGVITKEGSPIAMVIPTNEEWVIAEDSLRLVNK

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI1788633, Length=400, Percent_Identity=64, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI145693184, Length=393, Percent_Identity=46.3104325699746, Blast_Score=346, Evalue=2e-96,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ACKA_SHEAM (A1S5P6)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927372.1
- ProteinModelPortal:   A1S5P6
- SMR:   A1S5P6
- STRING:   A1S5P6
- GeneID:   4603747
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1495
- NMPDR:   fig|326297.7.peg.1411
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   PHLKDKN
- PhylomeDB:   A1S5P6
- ProtClustDB:   PRK00180
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 43424; Mature: 43293

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTLVLVLNCGSSSLKFAILDATNGDEKISGLAECFGLENARIKWKLRGEKHEASLGAF
CCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
SAHREAVEYIVNKILVNEPELKGQLIAIGHRIVHGGEKFTHSVIIDDAVLKGIEDCASLA
HHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHEECCCHHHHEEEEHHHHHHHHHHHHHHC
PLHNPAHLIGIRAAQASFPSLPQVAVFDTAFHQSMPDRAYIYALPYKLYREHGIRRYGMH
CCCCCHHEEEEEEHHCCCCCCCCHHEEHHHHHHCCCCCEEEEECCHHHHHHCCCEEECCC
GTSHLFVSREAAKALGKDVNDTNVICAHLGNGASVTAVKGGKSVDTSMGLTPLEGLVMGT
CCCEEEEEHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHEEEEC
RCGDLDPSIIYHLVHQLGYTLDEVNNLMNKQSGLLGISELTNDCRGIEEGYAEGHKGATL
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCCHH
ALEIFCYRLAKYIASYTVPLGRLDAIVFTGGIGENSDLIREKVLNLLEIFKFEVDSERNK
HHHHHHHHHHHHHHHHCCCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
AARFGNQGVITKEGSPIAMVIPTNEEWVIAEDSLRLVNK
HHHCCCCCEEEECCCCEEEEEECCCCEEEECCCHHHCCC
>Mature Secondary Structure 
SNTLVLVLNCGSSSLKFAILDATNGDEKISGLAECFGLENARIKWKLRGEKHEASLGAF
CCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
SAHREAVEYIVNKILVNEPELKGQLIAIGHRIVHGGEKFTHSVIIDDAVLKGIEDCASLA
HHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHEECCCHHHHEEEEHHHHHHHHHHHHHHC
PLHNPAHLIGIRAAQASFPSLPQVAVFDTAFHQSMPDRAYIYALPYKLYREHGIRRYGMH
CCCCCHHEEEEEEHHCCCCCCCCHHEEHHHHHHCCCCCEEEEECCHHHHHHCCCEEECCC
GTSHLFVSREAAKALGKDVNDTNVICAHLGNGASVTAVKGGKSVDTSMGLTPLEGLVMGT
CCCEEEEEHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHEEEEC
RCGDLDPSIIYHLVHQLGYTLDEVNNLMNKQSGLLGISELTNDCRGIEEGYAEGHKGATL
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCCHH
ALEIFCYRLAKYIASYTVPLGRLDAIVFTGGIGENSDLIREKVLNLLEIFKFEVDSERNK
HHHHHHHHHHHHHHHHCCCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
AARFGNQGVITKEGSPIAMVIPTNEEWVIAEDSLRLVNK
HHHCCCCCEEEECCCCEEEEEECCCCEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA