Click here to switch to the map view.

The map label for this gene is fur [H]

Identifier: 119774571

GI number: 119774571

Start: 1745162

End: 1745647

Strand: Reverse

Name: fur [H]

Synonym: Sama_1434

Alternate gene names: 119774571

Gene position: 1745647-1745162 (Counterclockwise)

Preceding gene: 119774574

Following gene: 119774559

Centisome position: 40.54

GC content: 48.97

Gene sequence:

>486_bases
ATGATTTCCATTGTCCACAAAGAGCCCAATGGTTCTGCAATCAAGAGATTAACCATGACAGATGGAAATCAGGCGCTGAA
AAAAGCGGGATTGAAAGTTACCCTGCCACGAGTAAAAATCCTGGAGCTGATGCAAGAACCAGAGAATCAACACATCAGTG
CCGAAGACCTGTACAAGAAGTTGCTCGAGATTGGTGAAGAGATTGGCCTGGCCACCGTGTACCGGGTACTGAACCAGTTC
GACGATGCGGGCATCGTCTCCCGTCACCACTTCGAAAGCGGCAAGGCCGTGTTCGAGCTGTCAACCCAACATCATCACGA
TCATCTGGTCTGTTTGAGCTGTGGCAAAGTGATTGAGTTTTCTGACGATTTGATTGAACGTCGTCAGAATGAAATTGCCA
TGCGCCACAACATTAAGCTCACCAACCACAGCCTGTATCTGTACGGCGTATGCACCAACGATACCTGTGATCACGGCGAC
GAGTAA

Upstream 100 bases:

>100_bases
GACCCAATCATGGACGATTGTCTGATACACCAGCAAATATTGCCATATGAGTTCATTTAAGGGCTATCAAAGGTTTAAGT
TTTGAATCCAGACACATATA

Downstream 100 bases:

>100_bases
TCGCTGTTTTCCCTAATAAAAAACCAGCGCTCCAGCGCTGGTTTTTTTATTGCTTTATCCTGAAGCGCGGCTTAATGCGC
GGACTACTCAGCGGTGAAAG

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MISIVHKEPNGSAIKRLTMTDGNQALKKAGLKVTLPRVKILELMQEPENQHISAEDLYKKLLEIGEEIGLATVYRVLNQF
DDAGIVSRHHFESGKAVFELSTQHHHDHLVCLSCGKVIEFSDDLIERRQNEIAMRHNIKLTNHSLYLYGVCTNDTCDHGD
E

Sequences:

>Translated_161_residues
MISIVHKEPNGSAIKRLTMTDGNQALKKAGLKVTLPRVKILELMQEPENQHISAEDLYKKLLEIGEEIGLATVYRVLNQF
DDAGIVSRHHFESGKAVFELSTQHHHDHLVCLSCGKVIEFSDDLIERRQNEIAMRHNIKLTNHSLYLYGVCTNDTCDHGD
E
>Mature_161_residues
MISIVHKEPNGSAIKRLTMTDGNQALKKAGLKVTLPRVKILELMQEPENQHISAEDLYKKLLEIGEEIGLATVYRVLNQF
DDAGIVSRHHFESGKAVFELSTQHHHDHLVCLSCGKVIEFSDDLIERRQNEIAMRHNIKLTNHSLYLYGVCTNDTCDHGD
E

Specific function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=138, Percent_Identity=76.8115942028985, Blast_Score=229, Evalue=8e-62,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18258; Mature: 18258

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISIVHKEPNGSAIKRLTMTDGNQALKKAGLKVTLPRVKILELMQEPENQHISAEDLYKK
CEEEEEECCCCCCEEEEEECCCHHHHHHCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHH
LLEIGEEIGLATVYRVLNQFDDAGIVSRHHFESGKAVFELSTQHHHDHLVCLSCGKVIEF
HHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEECCCCCCCEEEEEECCCEEEC
SDDLIERRQNEIAMRHNIKLTNHSLYLYGVCTNDTCDHGDE
CHHHHHHHHHHHHHHHCEEEECCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MISIVHKEPNGSAIKRLTMTDGNQALKKAGLKVTLPRVKILELMQEPENQHISAEDLYKK
CEEEEEECCCCCCEEEEEECCCHHHHHHCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHH
LLEIGEEIGLATVYRVLNQFDDAGIVSRHHFESGKAVFELSTQHHHDHLVCLSCGKVIEF
HHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEECCCCCCCEEEEEECCCEEEC
SDDLIERRQNEIAMRHNIKLTNHSLYLYGVCTNDTCDHGDE
CHHHHHHHHHHHHHHHCEEEECCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1372314 [H]