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The map label for this gene is ung [H]

Identifier: 119774366

GI number: 119774366

Start: 1513527

End: 1514183

Strand: Reverse

Name: ung [H]

Synonym: Sama_1229

Alternate gene names: 119774366

Gene position: 1514183-1513527 (Counterclockwise)

Preceding gene: 119774367

Following gene: 119774359

Centisome position: 35.16

GC content: 52.66

Gene sequence:

>657_bases
GTGGACTGGCAACAACTTCTTGGAGACGAAAAACGCTCTGCGTACTTCCAGGACACCCTTAAGTACATCAATGAGCGCAT
ACGCGCCGGAGTGACCGTCTATCCGGCCAAGGCCGATATCTTCAATGCGTTTCGATTTACTCCTCTGGAGCAGGTTAAGG
TGGTGATATTGGGGCAAGATCCTTACCACGGCCCCAATCAGGCACACGGTCTGTGCTTTTCAGTAAAATCCCCCTGTCCA
CCCCCTCCCTCTCTGCAGAACATCTTTATCGAGCTCACCAATTCAATCCCGGGCTTTATTGCCCCTTCCCATGGGGACTT
AACTCCTTGGGCAACTCAAGGCGTGTTGCTACTCAATACTATATTGACAGTGGAGCGCGGACAGGCACATTCCCACGCCC
ACCTGGGCTGGGAGCGGTTTACCGATGCAGTAATACGTGGCATCAGTACCCATTGTCACGGGGTGATATTTTTGCTTTGG
GGCAGCCATGCCGGCAAAAAAGCGGGCTTGATTGACGGCAGCAGACACAGAGTACTGCAAGCGCCGCACCCGTCACCGTT
CTCTGCACACAAAGGCTTTTTTGGTTGCAATCACTTTGCCATTGCCAATGACATGCTGAGACATCAGGGCAAATCTCCCA
TAGAGTGGCAACTCTGA

Upstream 100 bases:

>100_bases
CTGTAAGCACAAACGCATTGAAAAACGCCGCTCTGCGGCGTTTTTTTATGGCAGAAAATCAGCATAATAGACACAATCAG
CTAAAAATTAAGGACACAAA

Downstream 100 bases:

>100_bases
AACGGCTTATCCAACCCTCATAAAGCCTGCTAAACCTAGCCCTGATGACGAAACATCTTGGAACTCGCAAACAAAAATGC
CAGCCCGAGGGCTGGCATTT

Product: putative uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MDWQQLLGDEKRSAYFQDTLKYINERIRAGVTVYPAKADIFNAFRFTPLEQVKVVILGQDPYHGPNQAHGLCFSVKSPCP
PPPSLQNIFIELTNSIPGFIAPSHGDLTPWATQGVLLLNTILTVERGQAHSHAHLGWERFTDAVIRGISTHCHGVIFLLW
GSHAGKKAGLIDGSRHRVLQAPHPSPFSAHKGFFGCNHFAIANDMLRHQGKSPIEWQL

Sequences:

>Translated_218_residues
MDWQQLLGDEKRSAYFQDTLKYINERIRAGVTVYPAKADIFNAFRFTPLEQVKVVILGQDPYHGPNQAHGLCFSVKSPCP
PPPSLQNIFIELTNSIPGFIAPSHGDLTPWATQGVLLLNTILTVERGQAHSHAHLGWERFTDAVIRGISTHCHGVIFLLW
GSHAGKKAGLIDGSRHRVLQAPHPSPFSAHKGFFGCNHFAIANDMLRHQGKSPIEWQL
>Mature_218_residues
MDWQQLLGDEKRSAYFQDTLKYINERIRAGVTVYPAKADIFNAFRFTPLEQVKVVILGQDPYHGPNQAHGLCFSVKSPCP
PPPSLQNIFIELTNSIPGFIAPSHGDLTPWATQGVLLLNTILTVERGQAHSHAHLGWERFTDAVIRGISTHCHGVIFLLW
GSHAGKKAGLIDGSRHRVLQAPHPSPFSAHKGFFGCNHFAIANDMLRHQGKSPIEWQL

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=215, Percent_Identity=53.0232558139535, Blast_Score=242, Evalue=2e-64,
Organism=Homo sapiens, GI6224979, Length=216, Percent_Identity=52.7777777777778, Blast_Score=241, Evalue=3e-64,
Organism=Escherichia coli, GI1788934, Length=216, Percent_Identity=61.5740740740741, Blast_Score=285, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17556304, Length=215, Percent_Identity=46.5116279069767, Blast_Score=209, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6323620, Length=232, Percent_Identity=44.3965517241379, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24256; Mature: 24256

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWQQLLGDEKRSAYFQDTLKYINERIRAGVTVYPAKADIFNAFRFTPLEQVKVVILGQD
CCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCHHHEEEEEECCC
PYHGPNQAHGLCFSVKSPCPPPPSLQNIFIELTNSIPGFIAPSHGDLTPWATQGVLLLNT
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHH
ILTVERGQAHSHAHLGWERFTDAVIRGISTHCHGVIFLLWGSHAGKKAGLIDGSRHRVLQ
HHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCEEE
APHPSPFSAHKGFFGCNHFAIANDMLRHQGKSPIEWQL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDWQQLLGDEKRSAYFQDTLKYINERIRAGVTVYPAKADIFNAFRFTPLEQVKVVILGQD
CCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCHHHEEEEEECCC
PYHGPNQAHGLCFSVKSPCPPPPSLQNIFIELTNSIPGFIAPSHGDLTPWATQGVLLLNT
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHHHHH
ILTVERGQAHSHAHLGWERFTDAVIRGISTHCHGVIFLLWGSHAGKKAGLIDGSRHRVLQ
HHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCEEE
APHPSPFSAHKGFFGCNHFAIANDMLRHQGKSPIEWQL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA