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The map label for this gene is ppiD [H]

Identifier: 119774365

GI number: 119774365

Start: 1511561

End: 1513408

Strand: Direct

Name: ppiD [H]

Synonym: Sama_1228

Alternate gene names: 119774365

Gene position: 1511561-1513408 (Clockwise)

Preceding gene: 119774364

Following gene: 119774374

Centisome position: 35.1

GC content: 53.19

Gene sequence:

>1848_bases
ATGTTAGAAAAGATCCGTGAAGGTGCCCAGGGTACCATTGCCAAGAGCATTCTGGTGCTGGTCATACTTTCTTTTGCCTT
TACCGGTGTGAGCAGTTATCTCGGCTCATCCACCGAACCTGCGGCTGCCACAGTGAATGGAGAAGAAATTCCCGTCTCAG
CACTGGAGCAAGCCTTCCAAAATGAAAAGGCACGTATGGAGCAGCAACTGGGTGAGATGTTCCAGACCCTGGCCGCCGAC
GACAACTACCTGCGCTCCATCAGACAGGGTGTGCTCGAGCGTATGATTGCTGACAAATTGCTGGATCAAACTGCCAGTGA
AATGGGTCTGCGCATCTCCGATGAGCAAATCAAGCAAGCAATTATGGAAGAGCCCGCATTCCAAACAGAAGGCAAGTTTG
ATAACGAACGTTACCTGGCTATCCTGCGTCAGCTCGGATACCAAACCAACAGCTTCCGTGACATGATGCGTGTCGACATG
ACCCGTCGTCAGCTGGTGAACGCCCTGATTGGCAGTGAGTTTGTGCTGCCGTCTGAGAGCAAGGCGGTTGCTGAGCTGCA
AGGCCAGACACGTGACCTGCGCTATCTGGTGGTTGAGTCTCAGCCCTTCGAAGCGGGTATCACAGTGGCTGACGATGAAG
CCAAGAGCTTCTACGATGCCAATCCTGATCAGTTTATTAAACCTGAGCAGGTAAGCCTCGAATACCTGACGCTTTCTGCC
AAGTCCCTTGCCGATGAGGTGAGTGTGACCGACGAGCAGGCCAAAGCCTACTACGACGAGCACATGAGCCAGTACAAGAC
GCCTGAAAAACGTTTGGCTGCCCATATCCTGGTGAATCTGGGCGACGACGAAGCCGCCGCAAAAACCAAAGCCGATGCGA
TTTATGCCAAGCTTCAGGCCGGTGCAGACTTTGCCGAGCTTGCCAAAACCGACTCTGAAGACACTTTCAGCGGTGAGCTG
GGTGGTCAGCTGGACTGGTTTGAGCAGGGTGTAATGGATCCTGCGTTTGACGAAGCCTTGTTTGGTCTCGAAAAAGATCA
GTATTCTGCTGTGGTGAAAACCGACTATGGTTTCCACATTATCAAGCTGCTTGATGTTCAGGGCGGTGCCCAGGCCAGCT
TTGACGAAGTGAAGGATCGTATTTTCGCTCAGATCAAAGAAAAAGATGCGCTGGATAAGTTCTACAGTCTGCAGCAAAAA
CTGGCCGATACCAGTTACGAAGTCCCAGATAGCCTGACCGAAGCGGCCAAAGCCACCGGGCTTGAAGTAAAATCCACAGG
TCTTTTCGCCCGAGAAATGCCTCCGGCTGAAATCAGCAACCCAGCACTCATCAAAGCAGCCTTCTCTGAGCAGGTATTGC
TGAGCGGCATGAACAGCGACGTGGTTGACCTTGGCGACAACCAGGTTGCCGTGGTGCGCGTTAAAGAGCACAAGCAAGCC
GGTACTTTGCCATTCGATGAAGTGAAAGCCGGCATTGTTGCCCGCTTGACCCAAGACAAGGCCAACGATGCAGCCAAACT
GCAGGCGCAGGAACTGCTGGCCAAGTTCAAGGCCGGTGAAGCACTGGAGCTGACGGCCAAAGCCAAGGTTGCCCGTTTCG
ACCGTGAGTTGGATCCCTCCATCGTGAATAAGGGCTTCCAATTGGCCGTAGGCGGCGCTGATACCATCAGCATGGCTTCC
GGTTATGCGCTGGTAGTATTGGATAAGGTTAATCCAGCTGAGGGCGTTGAAGACGCTCTGGTGCAGGCCCTCGCTCAGCG
TCTGAGCAATCAGTATACAGAGCTTGCCTATCGCGGTGTTATCGACTCGCTGAAGGCGAAAGCCGAAATCAGTTACGCTG
CCGAATAA

Upstream 100 bases:

>100_bases
CGAAGCATTCAAGGTCATTCCTGAAAAGTTACATAAAGGCGCATCCTCAAAAAGATGCGCTTTTTTATTTCAATCACAAG
AGTAACAAGCGGGACGTCTG

Downstream 100 bases:

>100_bases
CGATAAGTTCCAGCATTAAAATGCCAGCCCTCGGGCTGGCATTTTTGTTTGCGAGTTCCAAGATGTTTCGTCATCAGGGC
TAGGTTTAGCAGGCTTTATG

Product: peptidyl-prolyl cis-trans isomerase D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MLEKIREGAQGTIAKSILVLVILSFAFTGVSSYLGSSTEPAAATVNGEEIPVSALEQAFQNEKARMEQQLGEMFQTLAAD
DNYLRSIRQGVLERMIADKLLDQTASEMGLRISDEQIKQAIMEEPAFQTEGKFDNERYLAILRQLGYQTNSFRDMMRVDM
TRRQLVNALIGSEFVLPSESKAVAELQGQTRDLRYLVVESQPFEAGITVADDEAKSFYDANPDQFIKPEQVSLEYLTLSA
KSLADEVSVTDEQAKAYYDEHMSQYKTPEKRLAAHILVNLGDDEAAAKTKADAIYAKLQAGADFAELAKTDSEDTFSGEL
GGQLDWFEQGVMDPAFDEALFGLEKDQYSAVVKTDYGFHIIKLLDVQGGAQASFDEVKDRIFAQIKEKDALDKFYSLQQK
LADTSYEVPDSLTEAAKATGLEVKSTGLFAREMPPAEISNPALIKAAFSEQVLLSGMNSDVVDLGDNQVAVVRVKEHKQA
GTLPFDEVKAGIVARLTQDKANDAAKLQAQELLAKFKAGEALELTAKAKVARFDRELDPSIVNKGFQLAVGGADTISMAS
GYALVVLDKVNPAEGVEDALVQALAQRLSNQYTELAYRGVIDSLKAKAEISYAAE

Sequences:

>Translated_615_residues
MLEKIREGAQGTIAKSILVLVILSFAFTGVSSYLGSSTEPAAATVNGEEIPVSALEQAFQNEKARMEQQLGEMFQTLAAD
DNYLRSIRQGVLERMIADKLLDQTASEMGLRISDEQIKQAIMEEPAFQTEGKFDNERYLAILRQLGYQTNSFRDMMRVDM
TRRQLVNALIGSEFVLPSESKAVAELQGQTRDLRYLVVESQPFEAGITVADDEAKSFYDANPDQFIKPEQVSLEYLTLSA
KSLADEVSVTDEQAKAYYDEHMSQYKTPEKRLAAHILVNLGDDEAAAKTKADAIYAKLQAGADFAELAKTDSEDTFSGEL
GGQLDWFEQGVMDPAFDEALFGLEKDQYSAVVKTDYGFHIIKLLDVQGGAQASFDEVKDRIFAQIKEKDALDKFYSLQQK
LADTSYEVPDSLTEAAKATGLEVKSTGLFAREMPPAEISNPALIKAAFSEQVLLSGMNSDVVDLGDNQVAVVRVKEHKQA
GTLPFDEVKAGIVARLTQDKANDAAKLQAQELLAKFKAGEALELTAKAKVARFDRELDPSIVNKGFQLAVGGADTISMAS
GYALVVLDKVNPAEGVEDALVQALAQRLSNQYTELAYRGVIDSLKAKAEISYAAE
>Mature_615_residues
MLEKIREGAQGTIAKSILVLVILSFAFTGVSSYLGSSTEPAAATVNGEEIPVSALEQAFQNEKARMEQQLGEMFQTLAAD
DNYLRSIRQGVLERMIADKLLDQTASEMGLRISDEQIKQAIMEEPAFQTEGKFDNERYLAILRQLGYQTNSFRDMMRVDM
TRRQLVNALIGSEFVLPSESKAVAELQGQTRDLRYLVVESQPFEAGITVADDEAKSFYDANPDQFIKPEQVSLEYLTLSA
KSLADEVSVTDEQAKAYYDEHMSQYKTPEKRLAAHILVNLGDDEAAAKTKADAIYAKLQAGADFAELAKTDSEDTFSGEL
GGQLDWFEQGVMDPAFDEALFGLEKDQYSAVVKTDYGFHIIKLLDVQGGAQASFDEVKDRIFAQIKEKDALDKFYSLQQK
LADTSYEVPDSLTEAAKATGLEVKSTGLFAREMPPAEISNPALIKAAFSEQVLLSGMNSDVVDLGDNQVAVVRVKEHKQA
GTLPFDEVKAGIVARLTQDKANDAAKLQAQELLAKFKAGEALELTAKAKVARFDRELDPSIVNKGFQLAVGGADTISMAS
GYALVVLDKVNPAEGVEDALVQALAQRLSNQYTELAYRGVIDSLKAKAEISYAAE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=629, Percent_Identity=34.6581875993641, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1786238, Length=101, Percent_Identity=38.6138613861386, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67378; Mature: 67378

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKIREGAQGTIAKSILVLVILSFAFTGVSSYLGSSTEPAAATVNGEEIPVSALEQAFQ
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHH
NEKARMEQQLGEMFQTLAADDNYLRSIRQGVLERMIADKLLDQTASEMGLRISDEQIKQA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IMEEPAFQTEGKFDNERYLAILRQLGYQTNSFRDMMRVDMTRRQLVNALIGSEFVLPSES
HHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KAVAELQGQTRDLRYLVVESQPFEAGITVADDEAKSFYDANPDQFIKPEQVSLEYLTLSA
HHHHHHCCCCCCEEEEEEECCCCCCCCEEECCHHHHHCCCCCCCCCCCCCCCCHHEEEEH
KSLADEVSVTDEQAKAYYDEHMSQYKTPEKRLAAHILVNLGDDEAAAKTKADAIYAKLQA
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHC
GADFAELAKTDSEDTFSGELGGQLDWFEQGVMDPAFDEALFGLEKDQYSAVVKTDYGFHI
CCCHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCHHHCEEEECCCCEEE
IKLLDVQGGAQASFDEVKDRIFAQIKEKDALDKFYSLQQKLADTSYEVPDSLTEAAKATG
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
LEVKSTGLFAREMPPAEISNPALIKAAFSEQVLLSGMNSDVVDLGDNQVAVVRVKEHKQA
CEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCC
GTLPFDEVKAGIVARLTQDKANDAAKLQAQELLAKFKAGEALELTAKAKVARFDRELDPS
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCHH
IVNKGFQLAVGGADTISMASGYALVVLDKVNPAEGVEDALVQALAQRLSNQYTELAYRGV
HHCCCCEEEECCCCHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IDSLKAKAEISYAAE
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MLEKIREGAQGTIAKSILVLVILSFAFTGVSSYLGSSTEPAAATVNGEEIPVSALEQAFQ
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHH
NEKARMEQQLGEMFQTLAADDNYLRSIRQGVLERMIADKLLDQTASEMGLRISDEQIKQA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IMEEPAFQTEGKFDNERYLAILRQLGYQTNSFRDMMRVDMTRRQLVNALIGSEFVLPSES
HHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KAVAELQGQTRDLRYLVVESQPFEAGITVADDEAKSFYDANPDQFIKPEQVSLEYLTLSA
HHHHHHCCCCCCEEEEEEECCCCCCCCEEECCHHHHHCCCCCCCCCCCCCCCCHHEEEEH
KSLADEVSVTDEQAKAYYDEHMSQYKTPEKRLAAHILVNLGDDEAAAKTKADAIYAKLQA
HHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHC
GADFAELAKTDSEDTFSGELGGQLDWFEQGVMDPAFDEALFGLEKDQYSAVVKTDYGFHI
CCCHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCHHHCEEEECCCCEEE
IKLLDVQGGAQASFDEVKDRIFAQIKEKDALDKFYSLQQKLADTSYEVPDSLTEAAKATG
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
LEVKSTGLFAREMPPAEISNPALIKAAFSEQVLLSGMNSDVVDLGDNQVAVVRVKEHKQA
CEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCC
GTLPFDEVKAGIVARLTQDKANDAAKLQAQELLAKFKAGEALELTAKAKVARFDRELDPS
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCHH
IVNKGFQLAVGGADTISMASGYALVVLDKVNPAEGVEDALVQALAQRLSNQYTELAYRGV
HHCCCCEEEECCCCHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IDSLKAKAEISYAAE
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]