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The map label for this gene is clpX [H]

Identifier: 119774362

GI number: 119774362

Start: 1507065

End: 1508342

Strand: Direct

Name: clpX [H]

Synonym: Sama_1225

Alternate gene names: 119774362

Gene position: 1507065-1508342 (Clockwise)

Preceding gene: 119774361

Following gene: 119774363

Centisome position: 35.0

GC content: 52.74

Gene sequence:

>1278_bases
ATGGGTGAGAACAAGACTGGTGATGGCGGCAAACTGCTGTATTGCTCTTTCTGCGGAAAGAGCCAGCACGAAGTGCGAAA
GCTGATCGCCGGACCATCCGTGTACGTCTGCGACGAGTGTGTTGAGTTGTGCAACGACATTATTCGCGAAGAGATTAAAG
AGATTTCGCCAAAGCGGGATCAGGACAAGCTGCCAACGCCTCACGAACTGAGAGCACACCTTGATGACTACGTCATTGGC
CAGGAAAAGGCCAAGAAGGTGCTGTCGGTGGCAGTGTACAACCACTATAAGCGCTTGCGTAATGCTGGCCCCAAAGATGG
GGTAGAGCTGGGTAAGAGTAACATTCTGCTGATTGGTCCAACCGGTAGTGGTAAGACCCTGTTGGCTGAAACGCTGGCGC
GTTTCCTCAATGTACCTTTCACCATGGCCGACGCCACTACGTTGACCGAAGCCGGTTATGTGGGTGAAGACGTTGAGAAC
ATCATTCAAAAGCTGCTGCAAAAGTGCGACTACGATGTGGAAAAGGCCCAGCGTGGCATCGTCTACATCGATGAAATCGA
TAAAATCAGCCGCAAGTCCGACAACCCCTCCATCACCCGTGATGTGAGTGGTGAAGGCGTGCAGCAAGCGCTGCTGAAAC
TTATTGAAGGGACCGTTGCTGCCGTGCCGCCACAGGGTGGCCGTAAACATCCGCAGCAGGAGTTTTTGCAGGTTGATACC
TCCAAGATCCTCTTTATCTGTGGTGGCGCTTTCGCCGGCCTCGAGAAGGTGATTGAGCAACGCACCCATACCGGTAGCGG
TATTGGTTTCGGTGCTCAAGTAAAGGGCAAGGAAGAAAAAGAGAGTATGTCTGACATTCTCTCGCAGGTTGAGCCGGAAG
ATCTGGTTAAATACGGTCTTATCCCTGAGTTCATCGGTCGTTTGCCTGTAGTCGCTACCCTGGCAGAGCTGGATGAAGAC
GCACTTATCCAAATTCTGTCAGAGCCCAAGAACGCACTTACCAAGCAATATGCGGCCCTGTTCGAGATGGAAAACGTTGA
GCTTGAATTCCGTGAAGACGCCCTGAAGGCAATCGCTCAAAAGGCCATGTCACGCAAGACAGGTGCCCGTGGTCTGCGCT
CGATTGTAGAAGGTATTCTGCTGGATACCATGTATGACTTGCCGTCCCAACAGGGTGTGAGCAAGGCTGTGGTGGATGAG
TCCGTGGTGAAGGGCGAGTCTGCACCGATCCTGATTTACGAACAGACCGAATCTCAGGCGGCCAGCGGCGACCAATAA

Upstream 100 bases:

>100_bases
CTGACCAGTCGCTGATTTTTGCATCGCTCTGGGCTAAGCTCAGATTGAAAGGTTGAGATAGAGAGACAAGCGACTGACAG
GTCGCAAACGGGGTAAACTA

Downstream 100 bases:

>100_bases
TTGCCCATCTGCAATGAATGTACGAATAAAGGAGTCCAATTGGGCTCCTTTTTTACATTTATGCCATTGAAAGGGCCGAA
ACAGCCCCAATATACTCGAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MGENKTGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRDQDKLPTPHELRAHLDDYVIG
QEKAKKVLSVAVYNHYKRLRNAGPKDGVELGKSNILLIGPTGSGKTLLAETLARFLNVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLEKVIEQRTHTGSGIGFGAQVKGKEEKESMSDILSQVEPEDLVKYGLIPEFIGRLPVVATLAELDED
ALIQILSEPKNALTKQYAALFEMENVELEFREDALKAIAQKAMSRKTGARGLRSIVEGILLDTMYDLPSQQGVSKAVVDE
SVVKGESAPILIYEQTESQAASGDQ

Sequences:

>Translated_425_residues
MGENKTGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRDQDKLPTPHELRAHLDDYVIG
QEKAKKVLSVAVYNHYKRLRNAGPKDGVELGKSNILLIGPTGSGKTLLAETLARFLNVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLEKVIEQRTHTGSGIGFGAQVKGKEEKESMSDILSQVEPEDLVKYGLIPEFIGRLPVVATLAELDED
ALIQILSEPKNALTKQYAALFEMENVELEFREDALKAIAQKAMSRKTGARGLRSIVEGILLDTMYDLPSQQGVSKAVVDE
SVVKGESAPILIYEQTESQAASGDQ
>Mature_424_residues
GENKTGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRDQDKLPTPHELRAHLDDYVIGQ
EKAKKVLSVAVYNHYKRLRNAGPKDGVELGKSNILLIGPTGSGKTLLAETLARFLNVPFTMADATTLTEAGYVGEDVENI
IQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTS
KILFICGGAFAGLEKVIEQRTHTGSGIGFGAQVKGKEEKESMSDILSQVEPEDLVKYGLIPEFIGRLPVVATLAELDEDA
LIQILSEPKNALTKQYAALFEMENVELEFREDALKAIAQKAMSRKTGARGLRSIVEGILLDTMYDLPSQQGVSKAVVDES
VVKGESAPILIYEQTESQAASGDQ

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=337, Percent_Identity=50.4451038575668, Blast_Score=308, Evalue=6e-84,
Organism=Escherichia coli, GI1786642, Length=424, Percent_Identity=81.3679245283019, Blast_Score=714, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=43, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=309, Percent_Identity=44.6601941747573, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI71982905, Length=324, Percent_Identity=43.5185185185185, Blast_Score=261, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=400, Percent_Identity=39.75, Blast_Score=250, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=41.40625, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=425, Percent_Identity=40.7058823529412, Blast_Score=275, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24648289, Length=332, Percent_Identity=46.6867469879518, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24648291, Length=332, Percent_Identity=46.6867469879518, Blast_Score=289, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46493; Mature: 46361

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGENKTGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRD
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
QDKLPTPHELRAHLDDYVIGQEKAKKVLSVAVYNHYKRLRNAGPKDGVELGKSNILLIGP
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEC
TGSGKTLLAETLARFLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGI
CCCCHHHHHHHHHHHHCCCCEECCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLEKVIEQRTHTGSGIGFGAQVKGKEEKESMSDILSQVEPEDLVKYGL
CCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCC
IPEFIGRLPVVATLAELDEDALIQILSEPKNALTKQYAALFEMENVELEFREDALKAIAQ
CHHHHCCHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KAMSRKTGARGLRSIVEGILLDTMYDLPSQQGVSKAVVDESVVKGESAPILIYEQTESQA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCC
ASGDQ
CCCCC
>Mature Secondary Structure 
GENKTGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRD
CCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
QDKLPTPHELRAHLDDYVIGQEKAKKVLSVAVYNHYKRLRNAGPKDGVELGKSNILLIGP
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEC
TGSGKTLLAETLARFLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGI
CCCCHHHHHHHHHHHHCCCCEECCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLEKVIEQRTHTGSGIGFGAQVKGKEEKESMSDILSQVEPEDLVKYGL
CCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCC
IPEFIGRLPVVATLAELDEDALIQILSEPKNALTKQYAALFEMENVELEFREDALKAIAQ
CHHHHCCHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KAMSRKTGARGLRSIVEGILLDTMYDLPSQQGVSKAVVDESVVKGESAPILIYEQTESQA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCC
ASGDQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA