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The map label for this gene is agaR [H]

Identifier: 119774330

GI number: 119774330

Start: 1462777

End: 1463559

Strand: Direct

Name: agaR [H]

Synonym: Sama_1193

Alternate gene names: 119774330

Gene position: 1462777-1463559 (Clockwise)

Preceding gene: 119774328

Following gene: 119774331

Centisome position: 33.97

GC content: 53.9

Gene sequence:

>783_bases
ATGAACATTCTCAACACCATAGAGAGACAACAGGAAATCGTGCGCCTGACCCAACAACAGGGAAAGGTGTCGGTAAGCGA
TTTGTCGGCACGCTTCGGAGTGTCAGAGGTCACCATTCGCAGTGACCTGGCAACCCTGGATCAAAAGCAGTTGCTGGTGC
GCTCCCGTGGCGGTGCCATCGTGAATACCGAGCTGAGCCGCGAGTTGTCCCTGAAGGAAAAAGGCAGTTGCTATTCGGCC
CTGAAACGGGAACTCGGCGCGGCGGCCGCAAGTCTGGTGCAAAACGGGGACCGACTGCTGCTCGACTCGGGTACCACCAC
AGAGCAAGTTGCCCATCATCTGATGCAGCACGAAGACCTTATCGTGATGACCAATGGACTGAACATAGCCTCTGTGCTGT
CCAAGTCAGACTCGGTGGAAGTGATGCTGACCGGTGGCCTGCTGCGTAAAAAGTCCATGTCCTTTTACGGCAGCGCTGCC
GAGAAGAGCCTGGGTGACTACAACTTCAACAAACTGATTCTTGGTGTGGACGGTTTCGACTTGAAGGCCGGACTGACCAC
CCATTTTGAAAAAGAAGCCTGTCTGAACCGGATGATGGTGGACATTGCCACTGAGGTCATAGTGGTGACCGACTCATCCA
AATTTGATCAGCAGGCCTTTCATGTGATCTGTCCTTTGCTTCGCATTCACAGGCTGGTCACTGACACAGGCATTCCTGAG
CGTTACGCCCAGGCACTCGAAAAACAAGGGGTGCAATTGCACCTGGTAGAACGCACTCAATAG

Upstream 100 bases:

>100_bases
TGAAAACATTAATGCGCCGTTTTGGTTGGTATCGAAACCTATTGAAAGTTTGTGTGCTGTGATACATTGAGGCTTTCGAA
CAAATGATGGGATAACCGAA

Downstream 100 bases:

>100_bases
CGATTTAAGGGGAGAACAATGGCGGGAATCGATCGTCGTGGATTTTTGAAGGCCTCTATGGCATCTGTGGCTGCAGCGGC
GCTGGCCGGTTGTGCCAGTC

Product: GlpR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNILNTIERQQEIVRLTQQQGKVSVSDLSARFGVSEVTIRSDLATLDQKQLLVRSRGGAIVNTELSRELSLKEKGSCYSA
LKRELGAAAASLVQNGDRLLLDSGTTTEQVAHHLMQHEDLIVMTNGLNIASVLSKSDSVEVMLTGGLLRKKSMSFYGSAA
EKSLGDYNFNKLILGVDGFDLKAGLTTHFEKEACLNRMMVDIATEVIVVTDSSKFDQQAFHVICPLLRIHRLVTDTGIPE
RYAQALEKQGVQLHLVERTQ

Sequences:

>Translated_260_residues
MNILNTIERQQEIVRLTQQQGKVSVSDLSARFGVSEVTIRSDLATLDQKQLLVRSRGGAIVNTELSRELSLKEKGSCYSA
LKRELGAAAASLVQNGDRLLLDSGTTTEQVAHHLMQHEDLIVMTNGLNIASVLSKSDSVEVMLTGGLLRKKSMSFYGSAA
EKSLGDYNFNKLILGVDGFDLKAGLTTHFEKEACLNRMMVDIATEVIVVTDSSKFDQQAFHVICPLLRIHRLVTDTGIPE
RYAQALEKQGVQLHLVERTQ
>Mature_260_residues
MNILNTIERQQEIVRLTQQQGKVSVSDLSARFGVSEVTIRSDLATLDQKQLLVRSRGGAIVNTELSRELSLKEKGSCYSA
LKRELGAAAASLVQNGDRLLLDSGTTTEQVAHHLMQHEDLIVMTNGLNIASVLSKSDSVEVMLTGGLLRKKSMSFYGSAA
EKSLGDYNFNKLILGVDGFDLKAGLTTHFEKEACLNRMMVDIATEVIVVTDSSKFDQQAFHVICPLLRIHRLVTDTGIPE
RYAQALEKQGVQLHLVERTQ

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=256, Percent_Identity=46.875, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI1789059, Length=247, Percent_Identity=37.246963562753, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI226510968, Length=247, Percent_Identity=31.9838056680162, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787540, Length=250, Percent_Identity=35.2, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789829, Length=248, Percent_Identity=30.6451612903226, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788069, Length=247, Percent_Identity=29.1497975708502, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790753, Length=250, Percent_Identity=27.6, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082344, Length=251, Percent_Identity=26.6932270916335, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1790635, Length=251, Percent_Identity=25.8964143426295, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787063, Length=247, Percent_Identity=23.4817813765182, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28657; Mature: 28657

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILNTIERQQEIVRLTQQQGKVSVSDLSARFGVSEVTIRSDLATLDQKQLLVRSRGGAI
CCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCEE
VNTELSRELSLKEKGSCYSALKRELGAAAASLVQNGDRLLLDSGTTTEQVAHHLMQHEDL
EECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCE
IVMTNGLNIASVLSKSDSVEVMLTGGLLRKKSMSFYGSAAEKSLGDYNFNKLILGVDGFD
EEEECCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHCCHHHHCCCCCCCCEEEEECCCCC
LKAGLTTHFEKEACLNRMMVDIATEVIVVTDSSKFDQQAFHVICPLLRIHRLVTDTGIPE
CCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
RYAQALEKQGVQLHLVERTQ
HHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure
MNILNTIERQQEIVRLTQQQGKVSVSDLSARFGVSEVTIRSDLATLDQKQLLVRSRGGAI
CCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCEE
VNTELSRELSLKEKGSCYSALKRELGAAAASLVQNGDRLLLDSGTTTEQVAHHLMQHEDL
EECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCE
IVMTNGLNIASVLSKSDSVEVMLTGGLLRKKSMSFYGSAAEKSLGDYNFNKLILGVDGFD
EEEECCCCHHHHHCCCCCEEEEEECCHHHHHHHHHHCCHHHHCCCCCCCCEEEEECCCCC
LKAGLTTHFEKEACLNRMMVDIATEVIVVTDSSKFDQQAFHVICPLLRIHRLVTDTGIPE
CCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
RYAQALEKQGVQLHLVERTQ
HHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]