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The map label for this gene is fabH [H]

Identifier: 119774319

GI number: 119774319

Start: 1445417

End: 1446466

Strand: Direct

Name: fabH [H]

Synonym: Sama_1182

Alternate gene names: 119774319

Gene position: 1445417-1446466 (Clockwise)

Preceding gene: 119774318

Following gene: 119774320

Centisome position: 33.57

GC content: 55.9

Gene sequence:

>1050_bases
ATGAAATATTCCCGCGTTTTTATCAACAGCATGGCCTATGAGTTGGCCCCTGTTGTGGTATCAAGCTCAGAGCTTGAACA
ACGTCTTGCTCCCCTGTATCAGAAGTTTCGTATACCCATGGGACAATTGGCTGCTCTTACGGGGATCCGTGAGCGCCGTT
GGTGGCCTCTGGGGCATCAGCTGTCCGATGGCGCCATTGCTGCTGCCAAGAAGGCACTGAATGAAACAGGCCTGAAGGCG
ACCGATTTGGGCGCCGTGGTGTATACCGGGGTGTGCCGTGACCAGCATGAACCTGCCACGGCGTGCCGCATCGCAGCATC
GCTGGGTGTGGGCCGTGACAGTGCTATCTACGACATTTCCAATGCCTGCCTGGGTGTACTCTCGGGCATTCTGGACATAG
CCAATCGCATTGAGCTTGGCCAAATTCGAGCCGGACTCGTTGTGTCCTGTGAATCGGCCCGCGACATTGTGGATGCCACC
ATTGAGCGGATGCTCGAAGAACCCACTATGCAGAATTTTGCCCAGTCGCTGGCGACCCTGACCGGTGGCTCCGGTGCGGT
TGCCGTATTGCTGACAGACGGCAGCTTCAACCTTGCTACCGAGCGAAACCATCAATTGCTGGGTGCCAGTCAATTGGCCG
CCCCTGAGCACTATCAGCTGTGCCAGTGGGGCCTGCAGGAAGCCGGACATCGCCTGTACCGTGAATTTATGCGTACAGAC
GCTGTGGCACTGCTCAAAGAAGGGGTAGAGCTTGCCAAACAAACCTGGCAACACTTCCTTGGACAGCGTGAATGGCTGGC
AAGTCAGGTGGACAAGGTGATTTGTCATCAGGTGGGCGCAGCCAATCGAAAACAAGTGCTCTCGGCACTGCAAATTCCTG
AAGAAAAAGAATTTCCCACTTTTGCCGAGCTTGGCAATATGGGCACAGTGTCTTTGCCGGTATCGGCGGCCATTGCCCAC
GACCAGGGTTTTTTACGTCCGGGGGATCAGGTCAGCTTCCTCGGCATAGGTTCGGGGCTGAACTGCATGATGTTGGGGCT
TCGCTGGTAA

Upstream 100 bases:

>100_bases
GGTTGGCGACAGCGGCATTTCTCTGGATAATGGCCCTCTAATATCGGGCCTTAACGGCATTCGGCCGGGCGTGCTTTGCA
TCCTAGATAACAAGAACTGA

Downstream 100 bases:

>100_bases
TGGATAATCATAAAATGCTGGATAGCCTGCTGCCTTTCAAACGCCGTTTTTTCAATCACGGCGGCCATAATATTCACTTT
ATCGATGAGGGACCAGAGGG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MKYSRVFINSMAYELAPVVVSSSELEQRLAPLYQKFRIPMGQLAALTGIRERRWWPLGHQLSDGAIAAAKKALNETGLKA
TDLGAVVYTGVCRDQHEPATACRIAASLGVGRDSAIYDISNACLGVLSGILDIANRIELGQIRAGLVVSCESARDIVDAT
IERMLEEPTMQNFAQSLATLTGGSGAVAVLLTDGSFNLATERNHQLLGASQLAAPEHYQLCQWGLQEAGHRLYREFMRTD
AVALLKEGVELAKQTWQHFLGQREWLASQVDKVICHQVGAANRKQVLSALQIPEEKEFPTFAELGNMGTVSLPVSAAIAH
DQGFLRPGDQVSFLGIGSGLNCMMLGLRW

Sequences:

>Translated_349_residues
MKYSRVFINSMAYELAPVVVSSSELEQRLAPLYQKFRIPMGQLAALTGIRERRWWPLGHQLSDGAIAAAKKALNETGLKA
TDLGAVVYTGVCRDQHEPATACRIAASLGVGRDSAIYDISNACLGVLSGILDIANRIELGQIRAGLVVSCESARDIVDAT
IERMLEEPTMQNFAQSLATLTGGSGAVAVLLTDGSFNLATERNHQLLGASQLAAPEHYQLCQWGLQEAGHRLYREFMRTD
AVALLKEGVELAKQTWQHFLGQREWLASQVDKVICHQVGAANRKQVLSALQIPEEKEFPTFAELGNMGTVSLPVSAAIAH
DQGFLRPGDQVSFLGIGSGLNCMMLGLRW
>Mature_349_residues
MKYSRVFINSMAYELAPVVVSSSELEQRLAPLYQKFRIPMGQLAALTGIRERRWWPLGHQLSDGAIAAAKKALNETGLKA
TDLGAVVYTGVCRDQHEPATACRIAASLGVGRDSAIYDISNACLGVLSGILDIANRIELGQIRAGLVVSCESARDIVDAT
IERMLEEPTMQNFAQSLATLTGGSGAVAVLLTDGSFNLATERNHQLLGASQLAAPEHYQLCQWGLQEAGHRLYREFMRTD
AVALLKEGVELAKQTWQHFLGQREWLASQVDKVICHQVGAANRKQVLSALQIPEEKEFPTFAELGNMGTVSLPVSAAIAH
DQGFLRPGDQVSFLGIGSGLNCMMLGLRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 37932; Mature: 37932

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSRVFINSMAYELAPVVVSSSELEQRLAPLYQKFRIPMGQLAALTGIRERRWWPLGHQ
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
LSDGAIAAAKKALNETGLKATDLGAVVYTGVCRDQHEPATACRIAASLGVGRDSAIYDIS
CCCCHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHH
NACLGVLSGILDIANRIELGQIRAGLVVSCESARDIVDATIERMLEEPTMQNFAQSLATL
HHHHHHHHHHHHHHHHCCHHHCCCCEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TGGSGAVAVLLTDGSFNLATERNHQLLGASQLAAPEHYQLCQWGLQEAGHRLYREFMRTD
CCCCCEEEEEEECCCCEECCCCCCHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVALLKEGVELAKQTWQHFLGQREWLASQVDKVICHQVGAANRKQVLSALQIPEEKEFPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCC
FAELGNMGTVSLPVSAAIAHDQGFLRPGDQVSFLGIGSGLNCMMLGLRW
HHHHCCCCEEECCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCC
>Mature Secondary Structure
MKYSRVFINSMAYELAPVVVSSSELEQRLAPLYQKFRIPMGQLAALTGIRERRWWPLGHQ
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
LSDGAIAAAKKALNETGLKATDLGAVVYTGVCRDQHEPATACRIAASLGVGRDSAIYDIS
CCCCHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHH
NACLGVLSGILDIANRIELGQIRAGLVVSCESARDIVDATIERMLEEPTMQNFAQSLATL
HHHHHHHHHHHHHHHHCCHHHCCCCEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TGGSGAVAVLLTDGSFNLATERNHQLLGASQLAAPEHYQLCQWGLQEAGHRLYREFMRTD
CCCCCEEEEEEECCCCEECCCCCCHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVALLKEGVELAKQTWQHFLGQREWLASQVDKVICHQVGAANRKQVLSALQIPEEKEFPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCC
FAELGNMGTVSLPVSAAIAHDQGFLRPGDQVSFLGIGSGLNCMMLGLRW
HHHHCCCCEEECCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA