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The map label for this gene is yaeL [C]

Identifier: 119774283

GI number: 119774283

Start: 1395382

End: 1396752

Strand: Direct

Name: yaeL [C]

Synonym: Sama_1146

Alternate gene names: 119774283

Gene position: 1395382-1396752 (Clockwise)

Preceding gene: 119774282

Following gene: 119774284

Centisome position: 32.4

GC content: 53.25

Gene sequence:

>1371_bases
ATGTACGACATCCTCTGGAATGCCGCATCTTTCATCGTTGCGCTGGGTTTGCTTATCACTGCGCACGAATACGGACACTT
TTATATTGCCCGGCGCTGTGGCGTGAAGGTGGAACGTTTCTCCATCGGCTTTGGTAAGCCCATCTGGCGTCGTGTTGGCC
AGGACGGTACCGAGTATGTCATTGCCATGATCCCACTCGGTGGCTATGTCAAAATGCTGGATGAGCGTGTTGACGAAGTG
CCAGCAGCGCTCCAGTCCCAGGCGTTTAATCGTAAAAACGTCTGGCAGCGCATCGCTATTGTGGCAGCAGGCCCGGTGGC
AAATTTTATTTTTGCGGTGTTTGCGCTCTACATCATGTACCTGATTGGCGTGCCTTCGTTAAAGCCGGTGATTAATGCGA
CCCATCAAAATTCTTCGGCGTCAGTCATCACAGTCACGGAACCCATGCAAATCCTTGCGGTCTCAGGACAGAAGGTGCGC
AACTGGGAAGAGGTTAATCTCGCCCTGGTTGGCCATATCGGGGATGACAGCCTGAGCCTGACACTGGCACCGCTCGCTCG
CCTGGAAGGGCAGAGCGGTGACGAGCGCACCTATACCCTGGATACCCGCAACTGGAAATTCGACCCGGAAAAGGAGTCGG
CTATCAGCACGCTTGGGCTGGGTATGCTGAGGCCTCAGGTGTTGCCCTTAGTGGCAGCCGTGACGCCAGGCAGCGCAGCA
GATGAAGCAGGTATCAAAGCCGGTGATGAGATTGTCGGTATCAATGGCGTCAGCTATGGCGGTTGGGAATGGTTCGTGGC
CACAATTCAGGCATCTTCCAACAAGCCGCTGCAAGTCACTATCAAACGGGGTGGCGAGCAAAAGCAACTGACCGCTACTC
CGAAACCCGGCAAAGATGCCCAGGGTAATGAGGTCGGCTTGATTGGTATTACACCTCAGGCCAGCGAACTGCCCGAATCC
ATGCGTATTCAGTTGAAATATGGCGTGTTAGACTCACTGGCTGTTGCTGCCGACAAAACCTGGCAGTTGACTGTGGTGAG
CGTAAAGATGATAGGTAAACTCTTTACCGGTGATGTGTCGGTGAAGAATCTGAGCGGTCCGATTTCAATCGCTCAGGGCG
CCGGGAATAGCGCCAACTACGGCTTGGTGTACTTTTTGGGATTTTTGGCTCTTATCAGCGTGAACCTGGGCATCATTAAC
CTGTTGCCTCTACCCGTGCTCGATGGGGGCCATTTGCTGTATTACTTTGTGGAAGTGATCACCGGGAAGCCTGTACCCGA
AAAGGTACAGGAAATAGGATTCAGATTTGGGGCAGCCTTGCTGCTAATGTTGATGAGTATCGCCCTTTTCAATGATTTTG
CCCGACTCTGA

Upstream 100 bases:

>100_bases
GGACTCACTGGATGCCATACTCGCGCTGGATTGGGAAGCGCGCCGACTGGCGAACCAACTGATTAGCCGGGTTTAATAGG
AATATACTCGAAGGAGAGAC

Downstream 100 bases:

>100_bases
GCAAGGACAGACAAATAATCAGAAGTGCTCTATGAGATTGAATAAGCTTTTTGCCTCTATGATGCTGCTAGGCGCATCAT
ATTCAGGGACAGGTCTGGCT

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MYDILWNAASFIVALGLLITAHEYGHFYIARRCGVKVERFSIGFGKPIWRRVGQDGTEYVIAMIPLGGYVKMLDERVDEV
PAALQSQAFNRKNVWQRIAIVAAGPVANFIFAVFALYIMYLIGVPSLKPVINATHQNSSASVITVTEPMQILAVSGQKVR
NWEEVNLALVGHIGDDSLSLTLAPLARLEGQSGDERTYTLDTRNWKFDPEKESAISTLGLGMLRPQVLPLVAAVTPGSAA
DEAGIKAGDEIVGINGVSYGGWEWFVATIQASSNKPLQVTIKRGGEQKQLTATPKPGKDAQGNEVGLIGITPQASELPES
MRIQLKYGVLDSLAVAADKTWQLTVVSVKMIGKLFTGDVSVKNLSGPISIAQGAGNSANYGLVYFLGFLALISVNLGIIN
LLPLPVLDGGHLLYYFVEVITGKPVPEKVQEIGFRFGAALLLMLMSIALFNDFARL

Sequences:

>Translated_456_residues
MYDILWNAASFIVALGLLITAHEYGHFYIARRCGVKVERFSIGFGKPIWRRVGQDGTEYVIAMIPLGGYVKMLDERVDEV
PAALQSQAFNRKNVWQRIAIVAAGPVANFIFAVFALYIMYLIGVPSLKPVINATHQNSSASVITVTEPMQILAVSGQKVR
NWEEVNLALVGHIGDDSLSLTLAPLARLEGQSGDERTYTLDTRNWKFDPEKESAISTLGLGMLRPQVLPLVAAVTPGSAA
DEAGIKAGDEIVGINGVSYGGWEWFVATIQASSNKPLQVTIKRGGEQKQLTATPKPGKDAQGNEVGLIGITPQASELPES
MRIQLKYGVLDSLAVAADKTWQLTVVSVKMIGKLFTGDVSVKNLSGPISIAQGAGNSANYGLVYFLGFLALISVNLGIIN
LLPLPVLDGGHLLYYFVEVITGKPVPEKVQEIGFRFGAALLLMLMSIALFNDFARL
>Mature_456_residues
MYDILWNAASFIVALGLLITAHEYGHFYIARRCGVKVERFSIGFGKPIWRRVGQDGTEYVIAMIPLGGYVKMLDERVDEV
PAALQSQAFNRKNVWQRIAIVAAGPVANFIFAVFALYIMYLIGVPSLKPVINATHQNSSASVITVTEPMQILAVSGQKVR
NWEEVNLALVGHIGDDSLSLTLAPLARLEGQSGDERTYTLDTRNWKFDPEKESAISTLGLGMLRPQVLPLVAAVTPGSAA
DEAGIKAGDEIVGINGVSYGGWEWFVATIQASSNKPLQVTIKRGGEQKQLTATPKPGKDAQGNEVGLIGITPQASELPES
MRIQLKYGVLDSLAVAADKTWQLTVVSVKMIGKLFTGDVSVKNLSGPISIAQGAGNSANYGLVYFLGFLALISVNLGIIN
LLPLPVLDGGHLLYYFVEVITGKPVPEKVQEIGFRFGAALLLMLMSIALFNDFARL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=456, Percent_Identity=51.7543859649123, Blast_Score=459, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49275; Mature: 49275

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDILWNAASFIVALGLLITAHEYGHFYIARRCGVKVERFSIGFGKPIWRRVGQDGTEYV
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCEEEEEECCCCCHHHHHHCCCCCEEE
IAMIPLGGYVKMLDERVDEVPAALQSQAFNRKNVWQRIAIVAAGPVANFIFAVFALYIMY
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
LIGVPSLKPVINATHQNSSASVITVTEPMQILAVSGQKVRNWEEVNLALVGHIGDDSLSL
HHCCCCCCHHHHCCCCCCCCEEEEEECCEEEEEECCCHHCCHHHEEEEEEEEECCCCCEE
TLAPLARLEGQSGDERTYTLDTRNWKFDPEKESAISTLGLGMLRPQVLPLVAAVTPGSAA
EEEHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCHHHHHHEEEECCCCCC
DEAGIKAGDEIVGINGVSYGGWEWFVATIQASSNKPLQVTIKRGGEQKQLTATPKPGKDA
CCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCEEEEEECCCCCCEEEECCCCCCCC
QGNEVGLIGITPQASELPESMRIQLKYGVLDSLAVAADKTWQLTVVSVKMIGKLFTGDVS
CCCEEEEEEECCCHHHCCHHHEEEEEECCHHHHHHHCCCCEEEEEEEHHHHHHHHCCCEE
VKNLSGPISIAQGAGNSANYGLVYFLGFLALISVNLGIINLLPLPVLDGGHLLYYFVEVI
EECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEECCCHHHHHHHHHH
TGKPVPEKVQEIGFRFGAALLLMLMSIALFNDFARL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYDILWNAASFIVALGLLITAHEYGHFYIARRCGVKVERFSIGFGKPIWRRVGQDGTEYV
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCEEEEEECCCCCHHHHHHCCCCCEEE
IAMIPLGGYVKMLDERVDEVPAALQSQAFNRKNVWQRIAIVAAGPVANFIFAVFALYIMY
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
LIGVPSLKPVINATHQNSSASVITVTEPMQILAVSGQKVRNWEEVNLALVGHIGDDSLSL
HHCCCCCCHHHHCCCCCCCCEEEEEECCEEEEEECCCHHCCHHHEEEEEEEEECCCCCEE
TLAPLARLEGQSGDERTYTLDTRNWKFDPEKESAISTLGLGMLRPQVLPLVAAVTPGSAA
EEEHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCHHHHHHEEEECCCCCC
DEAGIKAGDEIVGINGVSYGGWEWFVATIQASSNKPLQVTIKRGGEQKQLTATPKPGKDA
CCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCEEEEEECCCCCCEEEECCCCCCCC
QGNEVGLIGITPQASELPESMRIQLKYGVLDSLAVAADKTWQLTVVSVKMIGKLFTGDVS
CCCEEEEEEECCCHHHCCHHHEEEEEECCHHHHHHHCCCCEEEEEEEHHHHHHHHCCCEE
VKNLSGPISIAQGAGNSANYGLVYFLGFLALISVNLGIINLLPLPVLDGGHLLYYFVEVI
EECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEECCCHHHHHHHHHH
TGKPVPEKVQEIGFRFGAALLLMLMSIALFNDFARL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]