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The map label for this gene is cdsA [H]

Identifier: 119774281

GI number: 119774281

Start: 1393310

End: 1394167

Strand: Direct

Name: cdsA [H]

Synonym: Sama_1144

Alternate gene names: 119774281

Gene position: 1393310-1394167 (Clockwise)

Preceding gene: 119774280

Following gene: 119774282

Centisome position: 32.36

GC content: 53.73

Gene sequence:

>858_bases
TTGCTAAAACAACGAATAATAACAGCAATCTGGCTTATCCCACTGGTATTTGGCGCTATCTTCTATTTGCCTTCATCCAT
TTTTGCCTGGGCGCTGGTGGGCGTATTTTTAATTGCCGCAAAAGAGTGGGGACGCATTATTGATGCTGGTTGTCAGATGA
CCCAATGGAGCTTTACGCTGACCCTGGGCATTTTGCTGGTAGCCCTGAATATATTGGTGCCCGCATCCGAGGTCTGGCAC
TCCGGGCAATTGCACCCCATCTTTCTGGCTGTGACGCTGCTTGGCGGATTTTGGTGGGTCATCGCCATGGCACTGGTAGT
GACCTATCCCAAAAGCGCTCGTCTGTGGCAACGCAGCCATATGCTGAAATCCATGTTTGGTCAGCTGACGCTGCTGCCGT
GTTTTGTAGCGCTCATTGCCCTTAAATCCCTGAGCACCGATGCTTCACCCTACTTTGGTGGCGTAATGGTTTTCCTGGTG
ATGTTGGTGGTGTGGGCTGCTGACTCGGGGGCTTACTTTGTTGGCAAGGCACTGGGGCGCACCAAGCTTGCGCCCAATGT
CAGCCCCGCCAAAACGGTGGAAGGCCTGGTGGGCGGCTTGCTGACTACCATGATAGTGGTGGCTATTGTGATGAGCCTGT
CACCGCAGCAGGAGCTGGGGTTGGTGATTGCCGTGACCCTCTTTACTGCGCTCGCTTCGGCGCTCGGTGATTTAACCGAG
AGTATGTTCAAGCGGGTAGCCAACATTAAAGATTCTGGCACCATATTGCCGGGCCACGGTGGGGTGCTCGATCGCATCGA
CAGCCTCACAGCTGCGTTGCCAGTCTTTACCCTTATCTACATCGCCTTCTGGATGTAA

Upstream 100 bases:

>100_bases
GGCTATCGCTTTATTTGCGAGCCGCCAGCGCCGTTTTGGTTTGACCGGAAGTCAAATCGAAGCCTTGCGTGCTTAAGTCA
TCTTTTACGAGGGACGTTTT

Downstream 100 bases:

>100_bases
TCATGCAAAATCTGGTGATCCTTGGGGCCACAGGCTCTATCGGTAAAAGTACTCTGGATGTCATCAAACGTAACCCCGAG
CGTTATCGGGCGTTTGCCTT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLKQRIITAIWLIPLVFGAIFYLPSSIFAWALVGVFLIAAKEWGRIIDAGCQMTQWSFTLTLGILLVALNILVPASEVWH
SGQLHPIFLAVTLLGGFWWVIAMALVVTYPKSARLWQRSHMLKSMFGQLTLLPCFVALIALKSLSTDASPYFGGVMVFLV
MLVVWAADSGAYFVGKALGRTKLAPNVSPAKTVEGLVGGLLTTMIVVAIVMSLSPQQELGLVIAVTLFTALASALGDLTE
SMFKRVANIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM

Sequences:

>Translated_285_residues
MLKQRIITAIWLIPLVFGAIFYLPSSIFAWALVGVFLIAAKEWGRIIDAGCQMTQWSFTLTLGILLVALNILVPASEVWH
SGQLHPIFLAVTLLGGFWWVIAMALVVTYPKSARLWQRSHMLKSMFGQLTLLPCFVALIALKSLSTDASPYFGGVMVFLV
MLVVWAADSGAYFVGKALGRTKLAPNVSPAKTVEGLVGGLLTTMIVVAIVMSLSPQQELGLVIAVTLFTALASALGDLTE
SMFKRVANIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM
>Mature_285_residues
MLKQRIITAIWLIPLVFGAIFYLPSSIFAWALVGVFLIAAKEWGRIIDAGCQMTQWSFTLTLGILLVALNILVPASEVWH
SGQLHPIFLAVTLLGGFWWVIAMALVVTYPKSARLWQRSHMLKSMFGQLTLLPCFVALIALKSLSTDASPYFGGVMVFLV
MLVVWAADSGAYFVGKALGRTKLAPNVSPAKTVEGLVGGLLTTMIVVAIVMSLSPQQELGLVIAVTLFTALASALGDLTE
SMFKRVANIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=285, Percent_Identity=42.1052631578947, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1787677, Length=112, Percent_Identity=46.4285714285714, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30842; Mature: 30842

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQRIITAIWLIPLVFGAIFYLPSSIFAWALVGVFLIAAKEWGRIIDAGCQMTQWSFTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLGILLVALNILVPASEVWHSGQLHPIFLAVTLLGGFWWVIAMALVVTYPKSARLWQRSH
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MLKSMFGQLTLLPCFVALIALKSLSTDASPYFGGVMVFLVMLVVWAADSGAYFVGKALGR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
TKLAPNVSPAKTVEGLVGGLLTTMIVVAIVMSLSPQQELGLVIAVTLFTALASALGDLTE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SMFKRVANIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM
HHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLKQRIITAIWLIPLVFGAIFYLPSSIFAWALVGVFLIAAKEWGRIIDAGCQMTQWSFTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TLGILLVALNILVPASEVWHSGQLHPIFLAVTLLGGFWWVIAMALVVTYPKSARLWQRSH
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MLKSMFGQLTLLPCFVALIALKSLSTDASPYFGGVMVFLVMLVVWAADSGAYFVGKALGR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
TKLAPNVSPAKTVEGLVGGLLTTMIVVAIVMSLSPQQELGLVIAVTLFTALASALGDLTE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SMFKRVANIKDSGTILPGHGGVLDRIDSLTAALPVFTLIYIAFWM
HHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]