Click here to switch to the map view.

The map label for this gene is phoR [H]

Identifier: 119774212

GI number: 119774212

Start: 1301553

End: 1302857

Strand: Direct

Name: phoR [H]

Synonym: Sama_1075

Alternate gene names: 119774212

Gene position: 1301553-1302857 (Clockwise)

Preceding gene: 119774211

Following gene: 119774213

Centisome position: 30.23

GC content: 55.56

Gene sequence:

>1305_bases
ATGTTTGACTCTTATTCAGGGTATCGCCTGGCCTCCAGGCTGATGATTTACCTGCTTGTCACCCTGGCTCTCGGTTTGCT
CATTGGTGAGCTCAGCCTGACACTGTTGGCCGCATGTGTGGTACTGCTGTTTTGGCACTATCGCCAAATTGGCAGGCTGA
CCCACTGGCTGTGGTATGACAAACGTCTGACACCACCCCAGGGCAGCGGCAGTTGGGAAGGTATTTTCAACGGTCTCTAC
CGCCTTCAGGGAAAAAACCGTCGCAGGGTATCACAGCTTGCCGGTTTGCTTGGCCGCTTCCGTCAGGGGGCCGAAGCCCT
GCCCGATGCGGCTGTGGTGCTCGATTCCGATAAAAATATCCTCTGGTGTAACAAGCTTGCGCAGCTGATGCTGGGGCTGG
TATGGCCCCAGGACAATGGCCAGCGAATCGATAACCTCATTCGCCACCCGGATTTTTCGGCCTACCTGAAAACCCATGAC
TTTAAAGAACCGCTTGAGCTGCCTTCTCCTGTGTCTGACCAACGCCTACTTGAACTGAGGCTGATGAAATACGGAGACAG
GCAAATGCTGCTGATTGCCCGTGATATCACCCGTATCCGTCGGCTCGAAGGCATGCGAAAAGAGTTTGTTGCCAACGTTT
CCCACGAACTCAAGACACCGCTGACCGTGCTGCAGGGGTATCTGGAAATGATGCAGGGGATGACAGAGCCGGACGACATG
AATGCCAAACCGCTGGCGCTGATGCAGCAGCAGACAAGGCGTATGCAGTCCATGGTAGAGCAGCTGCTCACCTTGTCACG
TATTGAAGATGCGTCCGATGTTGATCTGGAAAAAACCGTAAACATGACACTCCTGATGGCCGCCATCAAAGATGAGGCTG
AAGCCCTGGCGCAGGGGGAGTATACCTTGCAGTTTGATGTACAGCAGGGGCTGAATGCCCATGGTAACGAGGTGCTGCTC
AGAAGTGCCTGCAGTAACCTGGTGTCCAACGCCATTCGTTATACGCCGCCCGGTGGCATTATCAAGGTCAGTTGGCGCCA
GATTGCCACCGGAGGCCGTTTTCAGGTGGAAGACACCGGTGAGGGGATAGCGCCGCAGCATATCGGCCGCCTGACCGAAC
GTTTTTACCGGGTCGACAGTGCCCGTTCCCGTGCGACGGGGGGCAGCGGTTTGGGGTTGGCGATTGTGAAGCACGCGCTG
GCCCACCACCATGCTGAGCTGTATGTCAGCAGCCAACTTGGCAAGGGCAGTATCTTCGGGTTTGTTATCCCTTCACATCT
TCTTGAGCCCAAAAAGGGCGCATAA

Upstream 100 bases:

>100_bases
CAGGATACCGTTTTTCCACTCGGGTTTAGTTCGGGATAGGCACAGTTAGCCGGATAGGTTATCTTGTGCCCCCAGACACA
ACCCTCGGCTGGATATAGCT

Downstream 100 bases:

>100_bases
GTGAGTTACCCAGACATAAAGACAGGCTTAGGCCTGTCTTTTCTTTTTGATAAATATTGAGTTTTAGCTTTTTTTGAAAA
AAATGTGTCGTGTCATCTAA

Product: phosphate regulon sensor protein PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MFDSYSGYRLASRLMIYLLVTLALGLLIGELSLTLLAACVVLLFWHYRQIGRLTHWLWYDKRLTPPQGSGSWEGIFNGLY
RLQGKNRRRVSQLAGLLGRFRQGAEALPDAAVVLDSDKNILWCNKLAQLMLGLVWPQDNGQRIDNLIRHPDFSAYLKTHD
FKEPLELPSPVSDQRLLELRLMKYGDRQMLLIARDITRIRRLEGMRKEFVANVSHELKTPLTVLQGYLEMMQGMTEPDDM
NAKPLALMQQQTRRMQSMVEQLLTLSRIEDASDVDLEKTVNMTLLMAAIKDEAEALAQGEYTLQFDVQQGLNAHGNEVLL
RSACSNLVSNAIRYTPPGGIIKVSWRQIATGGRFQVEDTGEGIAPQHIGRLTERFYRVDSARSRATGGSGLGLAIVKHAL
AHHHAELYVSSQLGKGSIFGFVIPSHLLEPKKGA

Sequences:

>Translated_434_residues
MFDSYSGYRLASRLMIYLLVTLALGLLIGELSLTLLAACVVLLFWHYRQIGRLTHWLWYDKRLTPPQGSGSWEGIFNGLY
RLQGKNRRRVSQLAGLLGRFRQGAEALPDAAVVLDSDKNILWCNKLAQLMLGLVWPQDNGQRIDNLIRHPDFSAYLKTHD
FKEPLELPSPVSDQRLLELRLMKYGDRQMLLIARDITRIRRLEGMRKEFVANVSHELKTPLTVLQGYLEMMQGMTEPDDM
NAKPLALMQQQTRRMQSMVEQLLTLSRIEDASDVDLEKTVNMTLLMAAIKDEAEALAQGEYTLQFDVQQGLNAHGNEVLL
RSACSNLVSNAIRYTPPGGIIKVSWRQIATGGRFQVEDTGEGIAPQHIGRLTERFYRVDSARSRATGGSGLGLAIVKHAL
AHHHAELYVSSQLGKGSIFGFVIPSHLLEPKKGA
>Mature_434_residues
MFDSYSGYRLASRLMIYLLVTLALGLLIGELSLTLLAACVVLLFWHYRQIGRLTHWLWYDKRLTPPQGSGSWEGIFNGLY
RLQGKNRRRVSQLAGLLGRFRQGAEALPDAAVVLDSDKNILWCNKLAQLMLGLVWPQDNGQRIDNLIRHPDFSAYLKTHD
FKEPLELPSPVSDQRLLELRLMKYGDRQMLLIARDITRIRRLEGMRKEFVANVSHELKTPLTVLQGYLEMMQGMTEPDDM
NAKPLALMQQQTRRMQSMVEQLLTLSRIEDASDVDLEKTVNMTLLMAAIKDEAEALAQGEYTLQFDVQQGLNAHGNEVLL
RSACSNLVSNAIRYTPPGGIIKVSWRQIATGGRFQVEDTGEGIAPQHIGRLTERFYRVDSARSRATGGSGLGLAIVKHAL
AHHHAELYVSSQLGKGSIFGFVIPSHLLEPKKGA

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=405, Percent_Identity=51.8518518518518, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=33.7662337662338, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788393, Length=216, Percent_Identity=32.4074074074074, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790346, Length=212, Percent_Identity=31.6037735849057, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790861, Length=315, Percent_Identity=29.2063492063492, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789403, Length=210, Percent_Identity=33.8095238095238, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787894, Length=238, Percent_Identity=29.8319327731092, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=28.2157676348548, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=28.936170212766, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=29.2035398230088, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=382, Percent_Identity=23.5602094240838, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790551, Length=207, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789808, Length=244, Percent_Identity=30.327868852459, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=402, Percent_Identity=23.8805970149254, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=274, Percent_Identity=22.992700729927, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=26.457399103139, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=217, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48802; Mature: 48802

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EECHHHHCCCCCCC
>Mature Secondary Structure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EECHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2556368 [H]