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The map label for this gene is purE [H]

Identifier: 119774201

GI number: 119774201

Start: 1289153

End: 1289644

Strand: Reverse

Name: purE [H]

Synonym: Sama_1064

Alternate gene names: 119774201

Gene position: 1289644-1289153 (Counterclockwise)

Preceding gene: 119774202

Following gene: 119774200

Centisome position: 29.95

GC content: 59.96

Gene sequence:

>492_bases
ATGCACGCCCTCGTTGCTGTCGTAATGGGTTCCAAGAGTGATTGGCCCACCATGGAAGCCGCCGCAGAGATCATGGATAA
ACTGCAGGTGCCTTACCATGTTGAGGTGGTTTCCGCCCACAGAACCCCGGACAAGTTAATGGACTTCGCCGCCACAGCAG
CTGACAAAGGCTTTCAGGTGATCATCGGTGGTGCCGGTGGCGCCGCACACCTGCCAGGCATGCTGGCCTCCAAAACCCGT
CTGCCAGTCCTCGGTGTACCCGTGCAGAGTAAGGCCCTCAACGGCATGGATTCTTTGCTGTCTATCGTGCAAATGCCAAA
GGGCATTGCCGTGGGCACCCTCGCCATCGGCACTGCCGGCGCCTTTAACGCAGGTCTGCTGGCTTGCCAAATTCTCGCCA
ACAACGACGCCGCCCTCGCCGAGCGCCTGGAGGCATTCCGCGCCGAACAGACCCAGAGCGTTCTGGAAAATCCGGATCCG
AGGGACGCGTAA

Upstream 100 bases:

>100_bases
TGGCAACGACTACCGAGGGGACTCCCCCGCAGCCAGGGTGCAAAGTACCCTCGCCTGAAAACAGGCAAATATAATTAAAA
TCAGTCGTTAAGGAGTTATC

Downstream 100 bases:

>100_bases
TCATGGCAAACACCAAACGCGTTTGGGTACTGGGCAATGGTCAGCTCGGTGCTATGCTGTCACACGCCGGTCAGCCACTG
GCCATCGAGGTGCTGCCGGT

Product: phosphoribosylaminoimidazole carboxylase

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MHALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMDFAATAADKGFQVIIGGAGGAAHLPGMLASKTR
LPVLGVPVQSKALNGMDSLLSIVQMPKGIAVGTLAIGTAGAFNAGLLACQILANNDAALAERLEAFRAEQTQSVLENPDP
RDA

Sequences:

>Translated_163_residues
MHALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMDFAATAADKGFQVIIGGAGGAAHLPGMLASKTR
LPVLGVPVQSKALNGMDSLLSIVQMPKGIAVGTLAIGTAGAFNAGLLACQILANNDAALAERLEAFRAEQTQSVLENPDP
RDA
>Mature_163_residues
MHALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMDFAATAADKGFQVIIGGAGGAAHLPGMLASKTR
LPVLGVPVQSKALNGMDSLLSIVQMPKGIAVGTLAIGTAGAFNAGLLACQILANNDAALAERLEAFRAEQTQSVLENPDP
RDA

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=161, Percent_Identity=70.8074534161491, Blast_Score=196, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6324702, Length=152, Percent_Identity=48.6842105263158, Blast_Score=151, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 16914; Mature: 16914

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMDFAATAADKGFQV
CCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEE
IIGGAGGAAHLPGMLASKTRLPVLGVPVQSKALNGMDSLLSIVQMPKGIAVGTLAIGTAG
EEECCCCHHHCCCHHHHCCCCCEECCCCHHHHHCCHHHHHHHHHCCCCCEEEHEECCCCC
AFNAGLLACQILANNDAALAERLEAFRAEQTQSVLENPDPRDA
CCHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMDFAATAADKGFQV
CCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEE
IIGGAGGAAHLPGMLASKTRLPVLGVPVQSKALNGMDSLLSIVQMPKGIAVGTLAIGTAG
EEECCCCHHHCCCHHHHCCCCCEECCCCHHHHHCCHHHHHHHHHCCCCCEEEHEECCCCC
AFNAGLLACQILANNDAALAERLEAFRAEQTQSVLENPDPRDA
CCHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA