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The map label for this gene is torR [H]

Identifier: 119774120

GI number: 119774120

Start: 1188516

End: 1189226

Strand: Direct

Name: torR [H]

Synonym: Sama_0983

Alternate gene names: 119774120

Gene position: 1188516-1189226 (Clockwise)

Preceding gene: 119774118

Following gene: 119774122

Centisome position: 27.6

GC content: 54.85

Gene sequence:

>711_bases
ATGGCCTACACAGTTTTGGTCGTCGATGATGAGGCGGTTATTCGCACCCGCCTGAAAGGCTACTTCAGCAAGGAAGGCTA
TCGGGTGTTGGAGGCCGCCAATGGGGAAGAAATGTGGCAACAATTGGCGCTGGCCCATGTGGATTTGATTATGCTGGATA
TCAATCTGCCGGGAACCGATGGTCTTTCGCTGACCCGGGAGCTCAGAAGTCGCTCTGACGTGGGCATCATTCTGGTGAGT
GGCCGGGATGAGACCGTCGATAGAATCGTTGGCCTTGAGATGGGGGCTGACGACTATGTCACCAAGCCCTTTGAGCTTAG
AGAGCTGTTGGTGCGGGTAAAAAACCTGCTGTGGCGTATCTCCTTGGTGGAAAAGGCTAAACAGCAGGCTGTAGCCGCCA
TGGATGAGGGCGATGACAGAATCGAGTTCGACGACTATGTGCTTGAACTTGGCAGTCGCAAGTTGTCCCGGGGCGAGGCG
GTTATCAAGCTCACCAAGGCGGAATTCGAGCTGCTGGTGGCTTTTGCGTTGCACCCACGGCAGGTGCTGTCGCGGGAGCG
TTTAATGCAGCAAACCAGCCATCGCAGTGAAGATGCCAACGACCGTACCATAGACGTGATTATCCGCCGCCTGCGCGGTA
AGCTCAATCCAGAGCTGTTTGTGACAGTTCATGGCGAAGGATATCTCTTTGCTGCCAGCGTCAGGGATTAA

Upstream 100 bases:

>100_bases
GCATTGGGGTTGCAAGCGGGATCTCAGTTCTTTCTCCCCGAATGTGAAATATGAAAAATTATGAATATACTGGTGCCAAT
CACGTTCCCGGAGATACCCC

Downstream 100 bases:

>100_bases
AGCGATAAACAGGATAAAACTCGGCAGGGGGTAAGGATTCAATCAGCGCTGCGGCATCGCTGTTGTTGGCCGTTCTGACT
ACAATCGCCGGTCCTATATC

Product: DNA-binding transcriptional regulator TorR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MAYTVLVVDDEAVIRTRLKGYFSKEGYRVLEAANGEEMWQQLALAHVDLIMLDINLPGTDGLSLTRELRSRSDVGIILVS
GRDETVDRIVGLEMGADDYVTKPFELRELLVRVKNLLWRISLVEKAKQQAVAAMDEGDDRIEFDDYVLELGSRKLSRGEA
VIKLTKAEFELLVAFALHPRQVLSRERLMQQTSHRSEDANDRTIDVIIRRLRGKLNPELFVTVHGEGYLFAASVRD

Sequences:

>Translated_236_residues
MAYTVLVVDDEAVIRTRLKGYFSKEGYRVLEAANGEEMWQQLALAHVDLIMLDINLPGTDGLSLTRELRSRSDVGIILVS
GRDETVDRIVGLEMGADDYVTKPFELRELLVRVKNLLWRISLVEKAKQQAVAAMDEGDDRIEFDDYVLELGSRKLSRGEA
VIKLTKAEFELLVAFALHPRQVLSRERLMQQTSHRSEDANDRTIDVIIRRLRGKLNPELFVTVHGEGYLFAASVRD
>Mature_235_residues
AYTVLVVDDEAVIRTRLKGYFSKEGYRVLEAANGEEMWQQLALAHVDLIMLDINLPGTDGLSLTRELRSRSDVGIILVSG
RDETVDRIVGLEMGADDYVTKPFELRELLVRVKNLLWRISLVEKAKQQAVAAMDEGDDRIEFDDYVLELGSRKLSRGEAV
IKLTKAEFELLVAFALHPRQVLSRERLMQQTSHRSEDANDRTIDVIIRRLRGKLNPELFVTVHGEGYLFAASVRD

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Phosphorylated torR activates the transcription of the torCAD operon by binding to four decameric boxes located in the torCAD p

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=53.1914893617021, Blast_Score=235, Evalue=2e-63,
Organism=Escherichia coli, GI1790863, Length=239, Percent_Identity=40.5857740585774, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=41.1016949152542, Blast_Score=166, Evalue=9e-43,
Organism=Escherichia coli, GI1786599, Length=239, Percent_Identity=36.8200836820084, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=34.7639484978541, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=36.3636363636364, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=34.051724137931, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=34.6153846153846, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=33.7662337662338, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=30.0847457627119, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87082012, Length=235, Percent_Identity=31.9148936170213, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=28.695652173913, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=28.0701754385965, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=35.0877192982456, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=30.6306306306306, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26814; Mature: 26683

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYTVLVVDDEAVIRTRLKGYFSKEGYRVLEAANGEEMWQQLALAHVDLIMLDINLPGTD
CEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHEEEEEEEEECCCCC
GLSLTRELRSRSDVGIILVSGRDETVDRIVGLEMGADDYVTKPFELRELLVRVKNLLWRI
CHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SLVEKAKQQAVAAMDEGDDRIEFDDYVLELGSRKLSRGEAVIKLTKAEFELLVAFALHPR
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCHH
QVLSRERLMQQTSHRSEDANDRTIDVIIRRLRGKLNPELFVTVHGEGYLFAASVRD
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCC
>Mature Secondary Structure 
AYTVLVVDDEAVIRTRLKGYFSKEGYRVLEAANGEEMWQQLALAHVDLIMLDINLPGTD
EEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHEEEEEEEEECCCCC
GLSLTRELRSRSDVGIILVSGRDETVDRIVGLEMGADDYVTKPFELRELLVRVKNLLWRI
CHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SLVEKAKQQAVAAMDEGDDRIEFDDYVLELGSRKLSRGEAVIKLTKAEFELLVAFALHPR
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCHH
QVLSRERLMQQTSHRSEDANDRTIDVIIRRLRGKLNPELFVTVHGEGYLFAASVRD
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]