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The map label for this gene is gluP [H]

Identifier: 119774085

GI number: 119774085

Start: 1148200

End: 1149525

Strand: Direct

Name: gluP [H]

Synonym: Sama_0948

Alternate gene names: 119774085

Gene position: 1148200-1149525 (Clockwise)

Preceding gene: 119774084

Following gene: 119774086

Centisome position: 26.66

GC content: 52.79

Gene sequence:

>1326_bases
ATGAACATGACAGTTGCGAGCGAGGCTCAGGTGAGCCGCAGAAGCAGCGTACTGCCGATGACCATTATCGGCATACTCTT
CTTCATCTTTGGATTTGTGACCTGGCTGAATGGTTCACTGATCCCTTTTCTGAAGGTTATCTGTGAGCTGAACGAGTTTC
AGGCACTGTTTGTCACTTTTGCCTTCTACATAGCCTACACGGTAATGGCCTTGCCTATGTCCTCCATTCTACGCCGTACC
GGTTACCGTAATGGTATGGCCATTGGTTTGGGCATCATGGTGGTGGGTAGCCTGGCTTTTATTCCAGCCGCATACAGCGC
CAACTTCCTGCTGTTTTTGGGTGCCCTGTTTATTCTGGGAACGGGTTTGACCATTCTGCAAACGGCATCCAACCCTTACG
TGGTTCATATCGGTCCCAAAGAAAGTGCGGCCATGCGGATCTCCATCATGGGAATTATCAACAAGCTCGCTGGTGTAGTG
GTTCCGCTGCTGTTTACTGCGTTGGTGTTGTCGGGGCTTGAAAACTTCGATGAAGCTCACCTGTCGGCATTGAGCGACGC
AGACCGAGCGGTGCAGATAACCGAGCTCTCAAGCCGCCTGGTGATGCCTTATATCTATATGGCCGTGGCGCTGCTTGCGC
TGATCGCGCTGGTGAAGTTCTCTGGTCTACCAGAACTTGAATTTGAAGAAGCCGAATCCGCCGAAGGCGAGAAGGGCAGT
ATCACCCAGTTTCCTCAGGTTATTCTGGGCGCCATAGCACTCTTTGCTTATGTGGGTATCGAGGTGATTGCCGGCGATAC
CATTGGTCTGTACGGTCAGTCGCTTGGGGTGGCCAATTTCGCGTCGCTTACTTCATACACCATGGTATTTATGGTGATTG
GTTATGCCATAGGTGTGCTCTGTATTCCGCGTTTTATCAGTCAGGAAAGGGCGTTGCTTGCCTCCGCCATTGCTGGTGGT
CTGTGTGTGCTTGGTGCTGTATTTGGTTCTACCGAAAGCACCACACTGGCCTCAGCCCTCTGGGGATGGATGGGGGTGCC
TTTGGTCCCCAACTCGGTAGTTTTTGTTGCCATGATGGGCCTAGCCCACGCGCTGGTGTGGCCTGCCGTTTGGCCTTTGG
CATTGGATGGCTTGGGCAAGTTTACCGCCCAGGGTTCGGCGTTGCTTATCATGGGGATTTCCGGTGGCGCCATTTTGCCC
CTGCTCTTTGGCAAGGTGGCCCATTTCAGCGGTGAGACTCAGCTGGGTTACTGGGTAGGCCTGCCATGCTATCTGTTCAT
CCTCTTCTATGCGGTGAAAGGACATAAGATGCGTAGCTGGAAATAA

Upstream 100 bases:

>100_bases
CAGATTGGCACAATGGTGCGGTGATATAACGAGTGCCGTTGGATGGATGGGATTGGGCTTACCCTGATCTTGATAAGAAA
CTATTAAAAGAAGCAGGCAT

Downstream 100 bases:

>100_bases
CCGCGGGTATCTGAAATATTGTCGGTTAAAAGGAGGCTAAGGCCTCCTTTTTGATGGGCGAGTTTTCCCCTTAAGCTGAT
AAGTGTCTGAGTTTGGGTGC

Product: multiple antibiotic resistance (MarC)-like protein

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MNMTVASEAQVSRRSSVLPMTIIGILFFIFGFVTWLNGSLIPFLKVICELNEFQALFVTFAFYIAYTVMALPMSSILRRT
GYRNGMAIGLGIMVVGSLAFIPAAYSANFLLFLGALFILGTGLTILQTASNPYVVHIGPKESAAMRISIMGIINKLAGVV
VPLLFTALVLSGLENFDEAHLSALSDADRAVQITELSSRLVMPYIYMAVALLALIALVKFSGLPELEFEEAESAEGEKGS
ITQFPQVILGAIALFAYVGIEVIAGDTIGLYGQSLGVANFASLTSYTMVFMVIGYAIGVLCIPRFISQERALLASAIAGG
LCVLGAVFGSTESTTLASALWGWMGVPLVPNSVVFVAMMGLAHALVWPAVWPLALDGLGKFTAQGSALLIMGISGGAILP
LLFGKVAHFSGETQLGYWVGLPCYLFILFYAVKGHKMRSWK

Sequences:

>Translated_441_residues
MNMTVASEAQVSRRSSVLPMTIIGILFFIFGFVTWLNGSLIPFLKVICELNEFQALFVTFAFYIAYTVMALPMSSILRRT
GYRNGMAIGLGIMVVGSLAFIPAAYSANFLLFLGALFILGTGLTILQTASNPYVVHIGPKESAAMRISIMGIINKLAGVV
VPLLFTALVLSGLENFDEAHLSALSDADRAVQITELSSRLVMPYIYMAVALLALIALVKFSGLPELEFEEAESAEGEKGS
ITQFPQVILGAIALFAYVGIEVIAGDTIGLYGQSLGVANFASLTSYTMVFMVIGYAIGVLCIPRFISQERALLASAIAGG
LCVLGAVFGSTESTTLASALWGWMGVPLVPNSVVFVAMMGLAHALVWPAVWPLALDGLGKFTAQGSALLIMGISGGAILP
LLFGKVAHFSGETQLGYWVGLPCYLFILFYAVKGHKMRSWK
>Mature_441_residues
MNMTVASEAQVSRRSSVLPMTIIGILFFIFGFVTWLNGSLIPFLKVICELNEFQALFVTFAFYIAYTVMALPMSSILRRT
GYRNGMAIGLGIMVVGSLAFIPAAYSANFLLFLGALFILGTGLTILQTASNPYVVHIGPKESAAMRISIMGIINKLAGVV
VPLLFTALVLSGLENFDEAHLSALSDADRAVQITELSSRLVMPYIYMAVALLALIALVKFSGLPELEFEEAESAEGEKGS
ITQFPQVILGAIALFAYVGIEVIAGDTIGLYGQSLGVANFASLTSYTMVFMVIGYAIGVLCIPRFISQERALLASAIAGG
LCVLGAVFGSTESTTLASALWGWMGVPLVPNSVVFVAMMGLAHALVWPAVWPLALDGLGKFTAQGSALLIMGISGGAILP
LLFGKVAHFSGETQLGYWVGLPCYLFILFYAVKGHKMRSWK

Specific function: Intake of glucose and galactose (Potential) [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=429, Percent_Identity=26.5734265734266, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005964
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47082; Mature: 47082

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMTVASEAQVSRRSSVLPMTIIGILFFIFGFVTWLNGSLIPFLKVICELNEFQALFVTF
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AFYIAYTVMALPMSSILRRTGYRNGMAIGLGIMVVGSLAFIPAAYSANFLLFLGALFILG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TGLTILQTASNPYVVHIGPKESAAMRISIMGIINKLAGVVVPLLFTALVLSGLENFDEAH
CCHHEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSALSDADRAVQITELSSRLVMPYIYMAVALLALIALVKFSGLPELEFEEAESAEGEKGS
HHHHHCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCC
ITQFPQVILGAIALFAYVGIEVIAGDTIGLYGQSLGVANFASLTSYTMVFMVIGYAIGVL
HHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CIPRFISQERALLASAIAGGLCVLGAVFGSTESTTLASALWGWMGVPLVPNSVVFVAMMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LAHALVWPAVWPLALDGLGKFTAQGSALLIMGISGGAILPLLFGKVAHFSGETQLGYWVG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHH
LPCYLFILFYAVKGHKMRSWK
HHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNMTVASEAQVSRRSSVLPMTIIGILFFIFGFVTWLNGSLIPFLKVICELNEFQALFVTF
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AFYIAYTVMALPMSSILRRTGYRNGMAIGLGIMVVGSLAFIPAAYSANFLLFLGALFILG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TGLTILQTASNPYVVHIGPKESAAMRISIMGIINKLAGVVVPLLFTALVLSGLENFDEAH
CCHHEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSALSDADRAVQITELSSRLVMPYIYMAVALLALIALVKFSGLPELEFEEAESAEGEKGS
HHHHHCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCC
ITQFPQVILGAIALFAYVGIEVIAGDTIGLYGQSLGVANFASLTSYTMVFMVIGYAIGVL
HHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CIPRFISQERALLASAIAGGLCVLGAVFGSTESTTLASALWGWMGVPLVPNSVVFVAMMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LAHALVWPAVWPLALDGLGKFTAQGSALLIMGISGGAILPLLFGKVAHFSGETQLGYWVG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHH
LPCYLFILFYAVKGHKMRSWK
HHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168605 [H]