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The map label for this gene is ndh [H]

Identifier: 119774073

GI number: 119774073

Start: 1129602

End: 1130891

Strand: Direct

Name: ndh [H]

Synonym: Sama_0936

Alternate gene names: 119774073

Gene position: 1129602-1130891 (Clockwise)

Preceding gene: 119774072

Following gene: 119774075

Centisome position: 26.23

GC content: 51.16

Gene sequence:

>1290_bases
GTGGGCACAAAGCGAATAGTCATAGTTGGCGGTGGTGCGGGTGGGCTTGCGTTGGCCTCAAAATTGGGGCGAAAGCTGGG
CCTGAAAAGCAAAGCCGACATTTTGCTCATAGATAGAAGCCCAATTCATATCTGGAAACCTAAGCTGCACGAAGTAGCAG
TCGGGGCCATAGACCAATCGATTGAAGGGTTGCTTTATCGCGATCATGGTTTAAAAAACGGCTACCGCTATCAGCGCGGC
TCGTTGGAAGCGCTGGACCCGGATGCAAAAACCATCCAACTGTCAGCGCTTTACAATGAGCGGCAAGAACTGCTGATGGG
GCCCCGTACCATAGAGTATGACTATCTGGTGCTCGCGCTTGGCGGTGTGTCCAACAGTTTCAATACCCCTGGCGCCGAAT
CTCACTGTATTTTTCTCGATAACCTGCAGAATGCTGAGCAATTTCACCGGCAATTGCTTGATGGACTGATGCTGCTGGAT
GAAACCCAATCACGTTTGAGCATTGGTATCGTTGGGGCTGGAGCGACGGGAGTTGAGCTTGCTGCTGAACTCCATCACGT
TGTTGAATCGGTCAGAGAATTTGGCTATCAGAATATTTCCAAGCAGCACCTGGATATACATCTTATCGAAGCCGCACCTA
AAATTTTGCCACAGCTACCCGATAGGGTCAGTGGCCGCGCGCAGGCAGTCCTCGATAAAATAGGCATTCACCTACATCTT
GGCGTGCAGGTTAAGGAAGTGACGAAAGAAGGTTTTACCACCCAGGATGGTAACCTTATCAGGGCGGATATCAGGGTTTG
GGCCGCAGGCGTTAAAGGCCCGAATGTGTTTTCAGACCTCAGCAAGTTACCCATCACCCCCAGAAATCAAGTGGAGGTGG
ATGCCTGTATGCGGGTCAAAGGGCACACAGATATTTATGCTTTGGGTGACTGCGCCCAGCTGATACTGGCTGATGGGAAG
CCCGTGCCTCCCAGAGCACAGGCGGCGTCGCAAATGGCTGAAACTTTATATCACAACATCCTAAACCGCCTGGCAGGGCA
GGCTGAAGCGCCATTCGAATATCGCGATTACGGTTCTCTGGTATCACTCAGTCGCTTCTCTGCTGTAGGCAATTTGATGG
GGAATTTAAGACGAGGTGATTTTTTTATTGAGGGGCACGTGGCTCGCTTTATGTACCTATCCCTCTATCATCGACATCTT
TCCAGTCTATTTGGCTGGTTTTCGGCGCTGGTGTATCGCTTGGCGCAAAAGCTGCTGCGATGGCAGCGCCCCAAGCTTAA
GTTGCATTGA

Upstream 100 bases:

>100_bases
CTTTTTGAACGCACATCTTATTCCATGAAGTTAATGTCAGCTTGTTTCGCTATATCGCTGTGATATAAAAGCAAAACGGA
ATGTACTACGGAGTATAGCT

Downstream 100 bases:

>100_bases
GCCCGTTTTTTTAACCTGGGTTGCTGCTGGAATCGCGGACAACAGGCTCGGGGGTGAACACCTTGGCACTGTCCAGGCGC
TGCTCTTTACGATTAGCAAT

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MGTKRIVIVGGGAGGLALASKLGRKLGLKSKADILLIDRSPIHIWKPKLHEVAVGAIDQSIEGLLYRDHGLKNGYRYQRG
SLEALDPDAKTIQLSALYNERQELLMGPRTIEYDYLVLALGGVSNSFNTPGAESHCIFLDNLQNAEQFHRQLLDGLMLLD
ETQSRLSIGIVGAGATGVELAAELHHVVESVREFGYQNISKQHLDIHLIEAAPKILPQLPDRVSGRAQAVLDKIGIHLHL
GVQVKEVTKEGFTTQDGNLIRADIRVWAAGVKGPNVFSDLSKLPITPRNQVEVDACMRVKGHTDIYALGDCAQLILADGK
PVPPRAQAASQMAETLYHNILNRLAGQAEAPFEYRDYGSLVSLSRFSAVGNLMGNLRRGDFFIEGHVARFMYLSLYHRHL
SSLFGWFSALVYRLAQKLLRWQRPKLKLH

Sequences:

>Translated_429_residues
MGTKRIVIVGGGAGGLALASKLGRKLGLKSKADILLIDRSPIHIWKPKLHEVAVGAIDQSIEGLLYRDHGLKNGYRYQRG
SLEALDPDAKTIQLSALYNERQELLMGPRTIEYDYLVLALGGVSNSFNTPGAESHCIFLDNLQNAEQFHRQLLDGLMLLD
ETQSRLSIGIVGAGATGVELAAELHHVVESVREFGYQNISKQHLDIHLIEAAPKILPQLPDRVSGRAQAVLDKIGIHLHL
GVQVKEVTKEGFTTQDGNLIRADIRVWAAGVKGPNVFSDLSKLPITPRNQVEVDACMRVKGHTDIYALGDCAQLILADGK
PVPPRAQAASQMAETLYHNILNRLAGQAEAPFEYRDYGSLVSLSRFSAVGNLMGNLRRGDFFIEGHVARFMYLSLYHRHL
SSLFGWFSALVYRLAQKLLRWQRPKLKLH
>Mature_428_residues
GTKRIVIVGGGAGGLALASKLGRKLGLKSKADILLIDRSPIHIWKPKLHEVAVGAIDQSIEGLLYRDHGLKNGYRYQRGS
LEALDPDAKTIQLSALYNERQELLMGPRTIEYDYLVLALGGVSNSFNTPGAESHCIFLDNLQNAEQFHRQLLDGLMLLDE
TQSRLSIGIVGAGATGVELAAELHHVVESVREFGYQNISKQHLDIHLIEAAPKILPQLPDRVSGRAQAVLDKIGIHLHLG
VQVKEVTKEGFTTQDGNLIRADIRVWAAGVKGPNVFSDLSKLPITPRNQVEVDACMRVKGHTDIYALGDCAQLILADGKP
VPPRAQAASQMAETLYHNILNRLAGQAEAPFEYRDYGSLVSLSRFSAVGNLMGNLRRGDFFIEGHVARFMYLSLYHRHLS
SLFGWFSALVYRLAQKLLRWQRPKLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=429, Percent_Identity=46.1538461538462, Blast_Score=381, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6323515, Length=464, Percent_Identity=26.9396551724138, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6323794, Length=361, Percent_Identity=28.808864265928, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320118, Length=353, Percent_Identity=26.3456090651558, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47452; Mature: 47321

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKRIVIVGGGAGGLALASKLGRKLGLKSKADILLIDRSPIHIWKPKLHEVAVGAIDQS
CCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHH
IEGLLYRDHGLKNGYRYQRGSLEALDPDAKTIQLSALYNERQELLMGPRTIEYDYLVLAL
HHHHEEECCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEECCCEEEEEE
GGVSNSFNTPGAESHCIFLDNLQNAEQFHRQLLDGLMLLDETQSRLSIGIVGAGATGVEL
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHH
AAELHHVVESVREFGYQNISKQHLDIHLIEAAPKILPQLPDRVSGRAQAVLDKIGIHLHL
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHCCCHHHCCHHHHHHHHCCEEEEE
GVQVKEVTKEGFTTQDGNLIRADIRVWAAGVKGPNVFSDLSKLPITPRNQVEVDACMRVK
CCCHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEHHHHHEEC
GHTDIYALGDCAQLILADGKPVPPRAQAASQMAETLYHNILNRLAGQAEAPFEYRDYGSL
CCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCH
VSLSRFSAVGNLMGNLRRGDFFIEGHVARFMYLSLYHRHLSSLFGWFSALVYRLAQKLLR
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQRPKLKLH
HCCCCCCCC
>Mature Secondary Structure 
GTKRIVIVGGGAGGLALASKLGRKLGLKSKADILLIDRSPIHIWKPKLHEVAVGAIDQS
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCHHHHHHHHHHHH
IEGLLYRDHGLKNGYRYQRGSLEALDPDAKTIQLSALYNERQELLMGPRTIEYDYLVLAL
HHHHEEECCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEECCCEEEEEE
GGVSNSFNTPGAESHCIFLDNLQNAEQFHRQLLDGLMLLDETQSRLSIGIVGAGATGVEL
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHH
AAELHHVVESVREFGYQNISKQHLDIHLIEAAPKILPQLPDRVSGRAQAVLDKIGIHLHL
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHCCCHHHCCHHHHHHHHCCEEEEE
GVQVKEVTKEGFTTQDGNLIRADIRVWAAGVKGPNVFSDLSKLPITPRNQVEVDACMRVK
CCCHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEHHHHHEEC
GHTDIYALGDCAQLILADGKPVPPRAQAASQMAETLYHNILNRLAGQAEAPFEYRDYGSL
CCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCH
VSLSRFSAVGNLMGNLRRGDFFIEGHVARFMYLSLYHRHLSSLFGWFSALVYRLAQKLLR
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQRPKLKLH
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]