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The map label for this gene is rppH [H]

Identifier: 119774000

GI number: 119774000

Start: 1053718

End: 1054254

Strand: Direct

Name: rppH [H]

Synonym: Sama_0863

Alternate gene names: 119774000

Gene position: 1053718-1054254 (Clockwise)

Preceding gene: 119773997

Following gene: 119774001

Centisome position: 24.47

GC content: 49.72

Gene sequence:

>537_bases
ATGTACTTTGGAGTCCATGTGATTGATAGCGACGGCTTTCGCGCAAATGTGGGCATCATCATCTGTAACGCTTATGGCCA
AGTCATGTGGGCCAGACGATTTGGACAACATTCATGGCAATTTCCCCAAGGGGGCCTGGATGACGGCGAAACTGCCGAAG
ATGCCATGTACCGTGAATTATACGAGGAAGTGGGCCTGAGGCCCGAACATGTACAAATCCTCACTTCAACACGATCCTGG
CTCAGGTATCGTTTGCCCAAACGTTTGGTACGGCAAGACAGTAGACCTGTCTGTATCGGGCAAAAACAGAAATGGTTTTT
GTTGATGCTCAAGAGTCAGGAAAGCGCCATTAATCTGAATTCTTCCGGTCATCCTGAATTTGATGACTGGCGTTGGGTCA
GTTATTGGTATCCTGTTCGGCAAGTCGTGTCGTTCAAGCGTGATGTTTACCGAAAGGTGATGAAAGAGTTTGCCCCTGTG
GCACTGGCGCTGCAGGCAAGGGAAATTCCACGGGGTAAGCGAAACAGAGGGCGGTAA

Upstream 100 bases:

>100_bases
TTGATAAGAGTGCTTACTACAGAGAATTATCCAAAGAAGTCCAGCAAATAGGGGTTTGCTGCCAGCTTGGCTTTGTGAAA
CAATCCTTCTATTACGATTT

Downstream 100 bases:

>100_bases
TCTTAACGGCGTGTCTGAAAATCGGGGGAGATAAAGGCAGTGCTCAATACGCTCAGGGATATCACACAATCGGTGGCGTC
GGCCCATACCCTCGAGTTGG

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MYFGVHVIDSDGFRANVGIIICNAYGQVMWARRFGQHSWQFPQGGLDDGETAEDAMYRELYEEVGLRPEHVQILTSTRSW
LRYRLPKRLVRQDSRPVCIGQKQKWFLLMLKSQESAINLNSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAPV
ALALQAREIPRGKRNRGR

Sequences:

>Translated_178_residues
MYFGVHVIDSDGFRANVGIIICNAYGQVMWARRFGQHSWQFPQGGLDDGETAEDAMYRELYEEVGLRPEHVQILTSTRSW
LRYRLPKRLVRQDSRPVCIGQKQKWFLLMLKSQESAINLNSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAPV
ALALQAREIPRGKRNRGR
>Mature_178_residues
MYFGVHVIDSDGFRANVGIIICNAYGQVMWARRFGQHSWQFPQGGLDDGETAEDAMYRELYEEVGLRPEHVQILTSTRSW
LRYRLPKRLVRQDSRPVCIGQKQKWFLLMLKSQESAINLNSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAPV
ALALQAREIPRGKRNRGR

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=159, Percent_Identity=74.2138364779874, Blast_Score=255, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 21025; Mature: 21025

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFGVHVIDSDGFRANVGIIICNAYGQVMWARRFGQHSWQFPQGGLDDGETAEDAMYREL
CEEEEEEECCCCCEEECCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
YEEVGLRPEHVQILTSTRSWLRYRLPKRLVRQDSRPVCIGQKQKWFLLMLKSQESAINLN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCEEECC
SSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAPVALALQAREIPRGKRNRGR
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MYFGVHVIDSDGFRANVGIIICNAYGQVMWARRFGQHSWQFPQGGLDDGETAEDAMYREL
CEEEEEEECCCCCEEECCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
YEEVGLRPEHVQILTSTRSWLRYRLPKRLVRQDSRPVCIGQKQKWFLLMLKSQESAINLN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCEEECC
SSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAPVALALQAREIPRGKRNRGR
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA