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The map label for this gene is cfa [H]

Identifier: 119773953

GI number: 119773953

Start: 1000686

End: 1001915

Strand: Direct

Name: cfa [H]

Synonym: Sama_0816

Alternate gene names: 119773953

Gene position: 1000686-1001915 (Clockwise)

Preceding gene: 119773952

Following gene: 119773954

Centisome position: 23.24

GC content: 53.33

Gene sequence:

>1230_bases
ATGGACAATACTGCAATTGCCAATAAGAGCACTTCATCGACGCTGGAATCTTTGGCCCAACGTATTTTGTTGACCGCACT
CAAAGGGCTTTCTTACGGTGGCCTGAGGATGATTTGTGATGGCGAGACTTTGGTGTTTGGCAGCCATCAGGGCCCTCAGG
CGGTGATCCATGTGAAGTCGCCAAGGTTTTTTCGTGAGGTGCTTCTGGCGGGCTCCGTTGGGGCGGGTGAGTCTTTTATC
GACGGTCACTGGGACAGTCCGAACCTGACCGAGGTCGTGCGCCTCTTCGCCGCTAACCTGCCGTTATTGGACAGGTTGGA
GAAGCGCTTTGCGTTTCTTTCGGGAGTTACCAACCGTATCAGTCATCTGCTCAGTCGTAACAGCATTGAAGGCTCAAAGC
GTAATATTCTGGCCCACTACGATTTGGGTAATGCGCTGTACGAGTGTTTCCTCGACAAATCGATGCTCTATTCCTCTGCA
ATCTATCCGGATGTCAATGCAACCCTGGAGGTAGCCCAGCAACACAAGCTCGCCACCATCTGCGAGCGCCTGAAGCTGGC
GCCTGGCATGGAACTTCTGGAGATAGGTACCGGCTGGGGAGCGCTCGCCATTTATGCGGCAACCCATTACGGGGTCAAGG
TGACGACGACCACCATCTCGGATGCGCAGCACGACTATGCCAAGGCACGAATTCGTGAGGCTGGGCTCGAAGGCCAAATC
ACCCTGCTCAAAAAGGACTATCGTCTGCTTGAAGGTAAGTACGACCGTCTGGTTTCCATTGAAATGATTGAAGCCGTTGG
ACACGAATACCTGCCCGGATTTTTCAGCAAACTCGAAAGTCTGCTCAAGGACGATGGTTTAATGCTGTTGCAGGCCATCA
CTATTGCCGACCAGAGATATGAGAGCTACAGAAAAGGTTGTGATTTTATTCAAAAATACATATTCCCCGGTGGCTGTTTG
CCGTCAGTGAGCCGGATGGCAAACCTGCTTGCCCAGCGTACCGACATGGTGATGCTGAGCCTGGATGATATTGGGGAAGA
TTACGCCCGCACCTTGAAGCACTGGCATGAGAACGTCGACCGAGAACAGCCGCAAATTCGCAGTCTGGGATACGACGAGC
GCTTTATCCGCCTGTGGAAGTTTTATCTGAGCTACTGCGAGGGTGGCTTCTGGGAGCGCACCACCAGTGCTGTGCATTTG
GTTGCCGCAAGACCGGGCTGGCGCCCTTAG

Upstream 100 bases:

>100_bases
TTACAGCATATATCCTGTATGGCATTTATCGGCAGGCCCTGAGCCTGTTTCGAAAAGGTGTGACTTTTGTGGCCCACCCC
GGGCCGGTGGAGAAATAACC

Downstream 100 bases:

>100_bases
ACATTCCGGAGCCCCTATGTCCCAGCGATGGTTTTTGCTTGTCAGCGCCGCTGTGTACACTGCCGCCTGGTGGCTTGCAG
TGCTTTGGCAAGGCGAGGGA

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MDNTAIANKSTSSTLESLAQRILLTALKGLSYGGLRMICDGETLVFGSHQGPQAVIHVKSPRFFREVLLAGSVGAGESFI
DGHWDSPNLTEVVRLFAANLPLLDRLEKRFAFLSGVTNRISHLLSRNSIEGSKRNILAHYDLGNALYECFLDKSMLYSSA
IYPDVNATLEVAQQHKLATICERLKLAPGMELLEIGTGWGALAIYAATHYGVKVTTTTISDAQHDYAKARIREAGLEGQI
TLLKKDYRLLEGKYDRLVSIEMIEAVGHEYLPGFFSKLESLLKDDGLMLLQAITIADQRYESYRKGCDFIQKYIFPGGCL
PSVSRMANLLAQRTDMVMLSLDDIGEDYARTLKHWHENVDREQPQIRSLGYDERFIRLWKFYLSYCEGGFWERTTSAVHL
VAARPGWRP

Sequences:

>Translated_409_residues
MDNTAIANKSTSSTLESLAQRILLTALKGLSYGGLRMICDGETLVFGSHQGPQAVIHVKSPRFFREVLLAGSVGAGESFI
DGHWDSPNLTEVVRLFAANLPLLDRLEKRFAFLSGVTNRISHLLSRNSIEGSKRNILAHYDLGNALYECFLDKSMLYSSA
IYPDVNATLEVAQQHKLATICERLKLAPGMELLEIGTGWGALAIYAATHYGVKVTTTTISDAQHDYAKARIREAGLEGQI
TLLKKDYRLLEGKYDRLVSIEMIEAVGHEYLPGFFSKLESLLKDDGLMLLQAITIADQRYESYRKGCDFIQKYIFPGGCL
PSVSRMANLLAQRTDMVMLSLDDIGEDYARTLKHWHENVDREQPQIRSLGYDERFIRLWKFYLSYCEGGFWERTTSAVHL
VAARPGWRP
>Mature_409_residues
MDNTAIANKSTSSTLESLAQRILLTALKGLSYGGLRMICDGETLVFGSHQGPQAVIHVKSPRFFREVLLAGSVGAGESFI
DGHWDSPNLTEVVRLFAANLPLLDRLEKRFAFLSGVTNRISHLLSRNSIEGSKRNILAHYDLGNALYECFLDKSMLYSSA
IYPDVNATLEVAQQHKLATICERLKLAPGMELLEIGTGWGALAIYAATHYGVKVTTTTISDAQHDYAKARIREAGLEGQI
TLLKKDYRLLEGKYDRLVSIEMIEAVGHEYLPGFFSKLESLLKDDGLMLLQAITIADQRYESYRKGCDFIQKYIFPGGCL
PSVSRMANLLAQRTDMVMLSLDDIGEDYARTLKHWHENVDREQPQIRSLGYDERFIRLWKFYLSYCEGGFWERTTSAVHL
VAARPGWRP

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=365, Percent_Identity=37.2602739726027, Blast_Score=209, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI133904226, Length=387, Percent_Identity=37.4677002583979, Blast_Score=233, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 45954; Mature: 45954

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNTAIANKSTSSTLESLAQRILLTALKGLSYGGLRMICDGETLVFGSHQGPQAVIHVKS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCEEEEECC
PRFFREVLLAGSVGAGESFIDGHWDSPNLTEVVRLFAANLPLLDRLEKRFAFLSGVTNRI
CHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SHLLSRNSIEGSKRNILAHYDLGNALYECFLDKSMLYSSAIYPDVNATLEVAQQHKLATI
HHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CERLKLAPGMELLEIGTGWGALAIYAATHYGVKVTTTTISDAQHDYAKARIREAGLEGQI
HHHHHCCCCCCEEEECCCCHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCCCEE
TLLKKDYRLLEGKYDRLVSIEMIEAVGHEYLPGFFSKLESLLKDDGLMLLQAITIADQRY
EEEHHHHHHHCCHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ESYRKGCDFIQKYIFPGGCLPSVSRMANLLAQRTDMVMLSLDDIGEDYARTLKHWHENVD
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEHHHCCHHHHHHHHHHHHHCC
REQPQIRSLGYDERFIRLWKFYLSYCEGGFWERTTSAVHLVAARPGWRP
CCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEECCCCCCC
>Mature Secondary Structure
MDNTAIANKSTSSTLESLAQRILLTALKGLSYGGLRMICDGETLVFGSHQGPQAVIHVKS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCEEEEECC
PRFFREVLLAGSVGAGESFIDGHWDSPNLTEVVRLFAANLPLLDRLEKRFAFLSGVTNRI
CHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SHLLSRNSIEGSKRNILAHYDLGNALYECFLDKSMLYSSAIYPDVNATLEVAQQHKLATI
HHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CERLKLAPGMELLEIGTGWGALAIYAATHYGVKVTTTTISDAQHDYAKARIREAGLEGQI
HHHHHCCCCCCEEEECCCCHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCCCEE
TLLKKDYRLLEGKYDRLVSIEMIEAVGHEYLPGFFSKLESLLKDDGLMLLQAITIADQRY
EEEHHHHHHHCCHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ESYRKGCDFIQKYIFPGGCLPSVSRMANLLAQRTDMVMLSLDDIGEDYARTLKHWHENVD
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEEEHHHCCHHHHHHHHHHHHHCC
REQPQIRSLGYDERFIRLWKFYLSYCEGGFWERTTSAVHLVAARPGWRP
CCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]