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The map label for this gene is hlyB [H]

Identifier: 119773904

GI number: 119773904

Start: 950251

End: 951891

Strand: Direct

Name: hlyB [H]

Synonym: Sama_0767

Alternate gene names: 119773904

Gene position: 950251-951891 (Clockwise)

Preceding gene: 119773903

Following gene: 119773906

Centisome position: 22.07

GC content: 54.84

Gene sequence:

>1641_bases
ATGCGTCTCAACGAGTTGACCATCAGAACCAAGTTTTCTATCCCCTTGATAATCATCGTTGTCATGACGGTTGCCATTGC
CGTAGTCAGTATTCTAAATGCCAAGCGGTTATCGTCCGATGCGCAGGAGCTGGCAACGACCTTTCTGTCAGCGGTGGACG
CGGGGTTGAATGCCGACCGGGATCTCTATCAGGCGCTCACAGCCAGCCAAAGTTATGTGCAGCACCGCTTGCTGGGGCAG
TCCGGTGGGGATAAATACCGTCAGGATTTTGATGAAAATGCCCAGCAGGCGCTGGACAGGATGGCGTTGGTGCTGAGCCT
GCTGAAGGATTACCCTGAGCTGCAGAGCAACAAAGCCCAGTTTCAGCGCGAATACGACGCCTGGCTGAACGCGGCCACTC
AGGTGTTCACCATGGTCGACAGCCAAAGCCCGGTCGCAGCAGCCAGTTATAACGACGAGGTTGTAATGCCACTGTTCAAG
GCATTGCGCGGACACTACGACAAAACCGGCGAGTGGGTAAAAAACAAAGCCGATGAAGTCACCAGTGAGGCACTGATTGC
CAGCCAGCGCGGCATCAACTTGCTGTTTGGCATAATTATTTTGGTGATACTGGCCAGTATTGTGAGTGTGGTTTATGGCC
CAAGGCTGGTAACTTCCCGGGTGGAACAGCTCGATACCATGATAGCCGCCATCAGTGATGGGGAAGGGGATCTGCGTGGC
AGACTCGATGACAGTGGTCGTGACGAGTTGTCACTGCTCGCCAGAACATTCAATGGCCTGATGATGAAGCTGCAACAACT
GATAGGAACCATCAAAAGCGATGCGGTTTCACTGGATGCCAGGGTGACCGGACTGAATCATTCAGCCAAAGAAAGCGAAA
AAATCTCCACCGAACAAAATGCCAATCTGGAGCAAATCGCCACGGCGGTGCATCAATTGAGTCATGCGGTGCATGAAGTG
GCGTCAAGCTCGCAAAATGCCCTCAGCGATACCGAGCACGCCAATAATCTTATCAAAGAGTCCAATGCCGTGGTGGGCCA
ATCCGTTGAGCGGGTACAGCAACTGGCCGGTGTGGTGTCCCATGCCAGCGAGGTGATTCAGAACCTCGCCTCCGAATCCA
AGCAAATCGTTACTGTGCTGGATGTGATCCGCGGCATTGCCGAGCAGACCAATCTGCTGGCGCTAAATGCCGCCATCGAA
GCGGCCAGGGCCGGTGAGCAGGGCCGTGGCTTTGCCGTGGTGGCAGACGAAGTGCGAACTCTGGCGAGTCGTACCCAGCA
ATCCACAGAGGATATTCAGCGAATGGTTGCCGGGCTCGAGTCGGGGGTGAGCGAAGCCGTGTCGGCGATAGACTCAGGAA
CCCGTCAGGTGGATTCAGTGGTTGACGCCTCGGGTAGCATTACCAAAGCCCTGGCAGAGGTGGATGAGGCAGTGTCCCGC
ACCAAAGATCTGATTTATCTGATTGCCACCGCTACCGAGCAGCAGAGCAAGGTGGTGGATGAGGTCAATCAGAACATCAG
CTCACTGAATCTGCTTTCTCAAGAGAGTATCGGTGTTGTCAGGCGTACCCGGGAGGCGGCCGACGAAATTGCCCAGATTG
GTACAGGGCTGTCGGGTAATGTGGGGCGCTTTTTGGTGTAA

Upstream 100 bases:

>100_bases
TCTCTGTGTGCTACATTTTTCAGAAAGCATCCTTCCCCGCGAAGGCGACGCCTTAGGGGCTTAGCCGGATGCAGGGGGCA
GCAAGCAGAGGAAGAAGTGT

Downstream 100 bases:

>100_bases
CTCTTGCGTAAGGCAGTTGTCAGAAAAGGGCCCTCCTGAGAGGGCCTTTCTTGTTATTGACGTCCAGTGACCGCAGCCGA
GGGCGCCACGGGGGCAAGTG

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MRLNELTIRTKFSIPLIIIVVMTVAIAVVSILNAKRLSSDAQELATTFLSAVDAGLNADRDLYQALTASQSYVQHRLLGQ
SGGDKYRQDFDENAQQALDRMALVLSLLKDYPELQSNKAQFQREYDAWLNAATQVFTMVDSQSPVAAASYNDEVVMPLFK
ALRGHYDKTGEWVKNKADEVTSEALIASQRGINLLFGIIILVILASIVSVVYGPRLVTSRVEQLDTMIAAISDGEGDLRG
RLDDSGRDELSLLARTFNGLMMKLQQLIGTIKSDAVSLDARVTGLNHSAKESEKISTEQNANLEQIATAVHQLSHAVHEV
ASSSQNALSDTEHANNLIKESNAVVGQSVERVQQLAGVVSHASEVIQNLASESKQIVTVLDVIRGIAEQTNLLALNAAIE
AARAGEQGRGFAVVADEVRTLASRTQQSTEDIQRMVAGLESGVSEAVSAIDSGTRQVDSVVDASGSITKALAEVDEAVSR
TKDLIYLIATATEQQSKVVDEVNQNISSLNLLSQESIGVVRRTREAADEIAQIGTGLSGNVGRFLV

Sequences:

>Translated_546_residues
MRLNELTIRTKFSIPLIIIVVMTVAIAVVSILNAKRLSSDAQELATTFLSAVDAGLNADRDLYQALTASQSYVQHRLLGQ
SGGDKYRQDFDENAQQALDRMALVLSLLKDYPELQSNKAQFQREYDAWLNAATQVFTMVDSQSPVAAASYNDEVVMPLFK
ALRGHYDKTGEWVKNKADEVTSEALIASQRGINLLFGIIILVILASIVSVVYGPRLVTSRVEQLDTMIAAISDGEGDLRG
RLDDSGRDELSLLARTFNGLMMKLQQLIGTIKSDAVSLDARVTGLNHSAKESEKISTEQNANLEQIATAVHQLSHAVHEV
ASSSQNALSDTEHANNLIKESNAVVGQSVERVQQLAGVVSHASEVIQNLASESKQIVTVLDVIRGIAEQTNLLALNAAIE
AARAGEQGRGFAVVADEVRTLASRTQQSTEDIQRMVAGLESGVSEAVSAIDSGTRQVDSVVDASGSITKALAEVDEAVSR
TKDLIYLIATATEQQSKVVDEVNQNISSLNLLSQESIGVVRRTREAADEIAQIGTGLSGNVGRFLV
>Mature_546_residues
MRLNELTIRTKFSIPLIIIVVMTVAIAVVSILNAKRLSSDAQELATTFLSAVDAGLNADRDLYQALTASQSYVQHRLLGQ
SGGDKYRQDFDENAQQALDRMALVLSLLKDYPELQSNKAQFQREYDAWLNAATQVFTMVDSQSPVAAASYNDEVVMPLFK
ALRGHYDKTGEWVKNKADEVTSEALIASQRGINLLFGIIILVILASIVSVVYGPRLVTSRVEQLDTMIAAISDGEGDLRG
RLDDSGRDELSLLARTFNGLMMKLQQLIGTIKSDAVSLDARVTGLNHSAKESEKISTEQNANLEQIATAVHQLSHAVHEV
ASSSQNALSDTEHANNLIKESNAVVGQSVERVQQLAGVVSHASEVIQNLASESKQIVTVLDVIRGIAEQTNLLALNAAIE
AARAGEQGRGFAVVADEVRTLASRTQQSTEDIQRMVAGLESGVSEAVSAIDSGTRQVDSVVDASGSITKALAEVDEAVSR
TKDLIYLIATATEQQSKVVDEVNQNISSLNLLSQESIGVVRRTREAADEIAQIGTGLSGNVGRFLV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=385, Percent_Identity=31.4285714285714, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI2367378, Length=426, Percent_Identity=27.9342723004695, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788195, Length=288, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=31.8559556786704, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1789453, Length=274, Percent_Identity=29.9270072992701, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58856; Mature: 58856

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNELTIRTKFSIPLIIIVVMTVAIAVVSILNAKRLSSDAQELATTFLSAVDAGLNADR
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCH
DLYQALTASQSYVQHRLLGQSGGDKYRQDFDENAQQALDRMALVLSLLKDYPELQSNKAQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHH
FQREYDAWLNAATQVFTMVDSQSPVAAASYNDEVVMPLFKALRGHYDKTGEWVKNKADEV
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
TSEALIASQRGINLLFGIIILVILASIVSVVYGPRLVTSRVEQLDTMIAAISDGEGDLRG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCC
RLDDSGRDELSLLARTFNGLMMKLQQLIGTIKSDAVSLDARVTGLNHSAKESEKISTEQN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCCCCC
ANLEQIATAVHQLSHAVHEVASSSQNALSDTEHANNLIKESNAVVGQSVERVQQLAGVVS
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HASEVIQNLASESKQIVTVLDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
LASRTQQSTEDIQRMVAGLESGVSEAVSAIDSGTRQVDSVVDASGSITKALAEVDEAVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TKDLIYLIATATEQQSKVVDEVNQNISSLNLLSQESIGVVRRTREAADEIAQIGTGLSGN
HHHHEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VGRFLV
CCCCCC
>Mature Secondary Structure
MRLNELTIRTKFSIPLIIIVVMTVAIAVVSILNAKRLSSDAQELATTFLSAVDAGLNADR
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCH
DLYQALTASQSYVQHRLLGQSGGDKYRQDFDENAQQALDRMALVLSLLKDYPELQSNKAQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHH
FQREYDAWLNAATQVFTMVDSQSPVAAASYNDEVVMPLFKALRGHYDKTGEWVKNKADEV
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
TSEALIASQRGINLLFGIIILVILASIVSVVYGPRLVTSRVEQLDTMIAAISDGEGDLRG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCC
RLDDSGRDELSLLARTFNGLMMKLQQLIGTIKSDAVSLDARVTGLNHSAKESEKISTEQN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCCCCC
ANLEQIATAVHQLSHAVHEVASSSQNALSDTEHANNLIKESNAVVGQSVERVQQLAGVVS
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HASEVIQNLASESKQIVTVLDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
LASRTQQSTEDIQRMVAGLESGVSEAVSAIDSGTRQVDSVVDASGSITKALAEVDEAVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TKDLIYLIATATEQQSKVVDEVNQNISSLNLLSQESIGVVRRTREAADEIAQIGTGLSGN
HHHHEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VGRFLV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]