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The map label for this gene is hlyB [H]

Identifier: 119773781

GI number: 119773781

Start: 798239

End: 799675

Strand: Direct

Name: hlyB [H]

Synonym: Sama_0643

Alternate gene names: 119773781

Gene position: 798239-799675 (Clockwise)

Preceding gene: 119773780

Following gene: 119773783

Centisome position: 18.54

GC content: 55.67

Gene sequence:

>1437_bases
ATGAAGCAGGTCGATTTTCGAACTATCGATAAAATTTTCATCCGCATGTCCATTAACGACAAGATGTGGGTTGTGTTTTT
GCTGTTTGTACTGGCACTGGGAACCACTGCCGGGTTGCGCTATTCCCAGAGTGTCGATGCCATAGAGGCAAGCTCGCTCA
AGGCTGCAGAAGCCCGATTGGCAGGTATGCTGGACACGCTGAATGCCACCGGCCAGTTTGAGAAAGCCGCCAGTCTTGGA
TTAACCACGGGGCGTGGCAAAAATCGCCATGATGGGGATTCAGTCACCGTCAGTGCCATTGCGGCCAATGGCCAGAGCTA
CTCGCTGGAACAGGATGTTCGCAGTCAGGAGAGCAAGGCACGCTCTGCGGCCAGTGCTGGCCTGCTTTGGACTGGCTTGT
GGCTGTTACCGTTTGGCCTGTTTTTATACTGGGTGGCCACCTTTATCGGCGGTGCCCTGTGGGTGCTGTACACCACCACA
GAGAAAATTGGCTCAGGGGATTTGACCTCTCGTTTAGGCTTCCACCCGGGGCGTGATGAGTTCGGTACCATTGGCTGTGC
ACTGGATAAAGCCATGGACACCCTCACTGAGCTCGTTAAGGTGGTGAAAGCCAACGCCGACACCCTGAGTGATACTTCCG
AGTCCTTTGAGCGGGAAATGAAGCAGAGCCTGCAGCAGATTAATCGCCAGTATGTGTCGCTGGACTCGGTTGCCACAGCC
ATGGAAGAAATGACGGCTTCAGCGCAGGAGGTGTCCAATATCTCCCGTCAGGCCACCGAAAAAACCGAGCAGGATGCCAC
CCAGGTGGAAAGCAGTTTCCAGCGGGTGCAAAAGGCCATTTCTGACATTGAGCAGCTGTCGGGGCTGATTGAACAGGCCT
CAAGTTCAGTGGCGACGCTCAATGTAAACACGACACAAATCAACGAAGTGATCACCACCATTAATGCGATTTCTGAGCAA
ACCAACCTGTTGGCGCTCAACGCCGCGATTGAGGCGGCCCGTGCGGGCGAACAGGGCAGGGGCTTTGCCGTGGTGGCAGA
CGAGGTGCGCACCCTGGCAAGCCGCACCCAGGCGGCAACCGTTGAAATTCAGGCCATGATTGAAAAACTGCAGGGCGAGA
GCCGTAACATCGCCAATATTACCGAAAAGACGGTCAGTCAGGCCCAGTCAAGCAGTGGGGTTATTGCCAACATAGGCGCG
GATGTGAGGGGTATTGCCGACTCCTCCCGTGCCATTACCGACATGAGCATCCAGATATCCACCTCCGCCGAAGAGCAGAG
CAGCGTGGCCAACAGTATTGCCGCAGAGCTCAGTGACATCCGTAACCAGTCCAACACCATACGTACGGTGGCGGAGCAGT
CATCGGAAGGGGTCGCCAGACTCGCTGAGGCCTCTCGCTCCCTGGGTAAGGTATTGGCCCGTTATCGCACCAATTGA

Upstream 100 bases:

>100_bases
TTTTGGGGAAAAACCACCTCAAATGTCCGGAAAGTGATTGAGCAAGATTTTGAATTTGGTGCAATAATAACAACTCGCCG
AATCGCGTTCTGGAGTACCA

Downstream 100 bases:

>100_bases
TGCTGGCGGTTTGCTGAAAGTCTCAGTTGTAGTTTGTCACTGAGATTGAAACCGAAAAAAGGACGCCGATGGCGTCCTTT
TTGTTAAAGCCAGCGTTTTC

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MKQVDFRTIDKIFIRMSINDKMWVVFLLFVLALGTTAGLRYSQSVDAIEASSLKAAEARLAGMLDTLNATGQFEKAASLG
LTTGRGKNRHDGDSVTVSAIAANGQSYSLEQDVRSQESKARSAASAGLLWTGLWLLPFGLFLYWVATFIGGALWVLYTTT
EKIGSGDLTSRLGFHPGRDEFGTIGCALDKAMDTLTELVKVVKANADTLSDTSESFEREMKQSLQQINRQYVSLDSVATA
MEEMTASAQEVSNISRQATEKTEQDATQVESSFQRVQKAISDIEQLSGLIEQASSSVATLNVNTTQINEVITTINAISEQ
TNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQAATVEIQAMIEKLQGESRNIANITEKTVSQAQSSSGVIANIGA
DVRGIADSSRAITDMSIQISTSAEEQSSVANSIAAELSDIRNQSNTIRTVAEQSSEGVARLAEASRSLGKVLARYRTN

Sequences:

>Translated_478_residues
MKQVDFRTIDKIFIRMSINDKMWVVFLLFVLALGTTAGLRYSQSVDAIEASSLKAAEARLAGMLDTLNATGQFEKAASLG
LTTGRGKNRHDGDSVTVSAIAANGQSYSLEQDVRSQESKARSAASAGLLWTGLWLLPFGLFLYWVATFIGGALWVLYTTT
EKIGSGDLTSRLGFHPGRDEFGTIGCALDKAMDTLTELVKVVKANADTLSDTSESFEREMKQSLQQINRQYVSLDSVATA
MEEMTASAQEVSNISRQATEKTEQDATQVESSFQRVQKAISDIEQLSGLIEQASSSVATLNVNTTQINEVITTINAISEQ
TNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQAATVEIQAMIEKLQGESRNIANITEKTVSQAQSSSGVIANIGA
DVRGIADSSRAITDMSIQISTSAEEQSSVANSIAAELSDIRNQSNTIRTVAEQSSEGVARLAEASRSLGKVLARYRTN
>Mature_478_residues
MKQVDFRTIDKIFIRMSINDKMWVVFLLFVLALGTTAGLRYSQSVDAIEASSLKAAEARLAGMLDTLNATGQFEKAASLG
LTTGRGKNRHDGDSVTVSAIAANGQSYSLEQDVRSQESKARSAASAGLLWTGLWLLPFGLFLYWVATFIGGALWVLYTTT
EKIGSGDLTSRLGFHPGRDEFGTIGCALDKAMDTLTELVKVVKANADTLSDTSESFEREMKQSLQQINRQYVSLDSVATA
MEEMTASAQEVSNISRQATEKTEQDATQVESSFQRVQKAISDIEQLSGLIEQASSSVATLNVNTTQINEVITTINAISEQ
TNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQAATVEIQAMIEKLQGESRNIANITEKTVSQAQSSSGVIANIGA
DVRGIADSSRAITDMSIQISTSAEEQSSVANSIAAELSDIRNQSNTIRTVAEQSSEGVARLAEASRSLGKVLARYRTN

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=280, Percent_Identity=29.2857142857143, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787690, Length=312, Percent_Identity=29.4871794871795, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788194, Length=345, Percent_Identity=28.1159420289855, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI2367378, Length=307, Percent_Identity=27.6872964169381, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789453, Length=256, Percent_Identity=28.515625, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 51309; Mature: 51309

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVDFRTIDKIFIRMSINDKMWVVFLLFVLALGTTAGLRYSQSVDAIEASSLKAAEARL
CCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHH
AGMLDTLNATGQFEKAASLGLTTGRGKNRHDGDSVTVSAIAANGQSYSLEQDVRSQESKA
HHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHH
RSAASAGLLWTGLWLLPFGLFLYWVATFIGGALWVLYTTTEKIGSGDLTSRLGFHPGRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEEHHHCCCCCHHHHCCCCCCCCC
FGTIGCALDKAMDTLTELVKVVKANADTLSDTSESFEREMKQSLQQINRQYVSLDSVATA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEEMTASAQEVSNISRQATEKTEQDATQVESSFQRVQKAISDIEQLSGLIEQASSSVATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NVNTTQINEVITTINAISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQAAT
ECCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHH
VEIQAMIEKLQGESRNIANITEKTVSQAQSSSGVIANIGADVRGIADSSRAITDMSIQIS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCEEEEEEEEE
TSAEEQSSVANSIAAELSDIRNQSNTIRTVAEQSSEGVARLAEASRSLGKVLARYRTN
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQVDFRTIDKIFIRMSINDKMWVVFLLFVLALGTTAGLRYSQSVDAIEASSLKAAEARL
CCCCCHHHHHHHEEEEECCCHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHH
AGMLDTLNATGQFEKAASLGLTTGRGKNRHDGDSVTVSAIAANGQSYSLEQDVRSQESKA
HHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHH
RSAASAGLLWTGLWLLPFGLFLYWVATFIGGALWVLYTTTEKIGSGDLTSRLGFHPGRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEEHHHCCCCCHHHHCCCCCCCCC
FGTIGCALDKAMDTLTELVKVVKANADTLSDTSESFEREMKQSLQQINRQYVSLDSVATA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEEMTASAQEVSNISRQATEKTEQDATQVESSFQRVQKAISDIEQLSGLIEQASSSVATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NVNTTQINEVITTINAISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQAAT
ECCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHH
VEIQAMIEKLQGESRNIANITEKTVSQAQSSSGVIANIGADVRGIADSSRAITDMSIQIS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCEEEEEEEEE
TSAEEQSSVANSIAAELSDIRNQSNTIRTVAEQSSEGVARLAEASRSLGKVLARYRTN
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]