Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 119773760

GI number: 119773760

Start: 775744

End: 777363

Strand: Direct

Name: hlyB [H]

Synonym: Sama_0622

Alternate gene names: 119773760

Gene position: 775744-777363 (Clockwise)

Preceding gene: 119773759

Following gene: 119773761

Centisome position: 18.01

GC content: 51.48

Gene sequence:

>1620_bases
ATGACATGGTTTAATAACCTTCCCATCTTTAAAAAAGTCGGTGTCATCTTCATCATTTCGGTGATCATCTTTGCGGTGAA
TCTGGCCATCAGTCTGGTCTCTATCAATAAAAATCGCGAAACCCTGGGATTTATGGAAGAGAAGATTTACCAGCGGGTTG
AACTGGCCAACCAAAATTTGATGTTGGTGCAGCGGCTTGAGGAGGTATACACCCAGGCGGTGTCATTTGCCGATGAAGAC
CTATTGGAGCAAGCCGGCAGCCTGCATGACAACCTTGCCGCCAACCTTACGTTGTTACAGAGCTCAGACATAAAAGAAAC
CGACACGCTTCGACAGATGCTGTCGCAGCTCGCCAGCTATAACCAAATAACCTCTGGCCTGGCAAAGAGCATGTTGGATG
GAACTGCAGACATGGCCAACATAGGCGCCATCAGTCAGAAAAAGTCCGCTGTGTATGAAACCCTGCTGGGTCATGTGCAG
CAATACAAGCAGGCCAAGGTATTGGAGTTCAAAAATACCATCAAGGAGGCAGCAGACAGATCGCAAAACAGTCTCTGGTT
GACCATGGTGGTGGGAGTGGTGCTGCTGCTGTTTATGGCCATAGTGACCATATCCATCGCCCGTGCTATCAGCGCCAGTG
CTAAAGGGGTGGCCCATTCCCTTGGTGAACTCGCCGATGGCAAGGGAGATTTGCGCCACCAACTACCAGCCAGCAGTCGG
GACGAACTCGGGCAGGTATCCGGTAACTTCAATCGCTTTTTGGGACTCCTGGCAGGCTCAATCCAGAGGGTGGTGAATGT
AACCTCGCCGTTACTCAACAACGCCCATGATTTGAAAGACAAGATGGAAACGGCAACGGGCGCTACCCAGCGTCAGAGTC
ATGATGCTCAAACCGTTCAGGCATCTATGGAAGAGATGCGGCTGTCGGTAATTGATATTTCCCATAATGCCAGTCAGGCG
GCAGATGCAGCGCAAATAGCAGAGCGTGAAGCCATGGACGGGATGGCGGTGGTGCAGCGTACCATGGACATCTCCCTGGA
GTTGAACCGCGAAATTGAACATGCGGCCAACGCCATTAATGAATTGGCAAAAGATACTGAAAGTGTCAGTTCGATACTGA
ATGTCATCACCTCCATCGCCGAGCAAACCAACCTGTTGGCACTGAATGCGGCCATTGAGGCTGCCCGCGCCGGAGAGCAG
GGCAGAGGTTTTGCCGTTGTAGCAGACGAAGTGCGTGCTCTGGCTTCGAAAACCGCCGATGCCACCAAGGAAATTCGTGA
GGTGCTGACCAGGCTCAAGGGCGCCGCAGAGTCGTCAGTCAGTACCATGACGGTGGCCATGTCCAAGTCGAGTGAGAACG
AGGAGCATGCCCAGAAGACGGGGTTGGCACTCAAGACGATTCAAGAACAAATTGTCAGTATCAATGCCATGAACACCCAT
ATTGCCAGGTCAACCGATGAACAGTCTCAGGTGGCCTCCAGGGTGGTGGATAATGTGGTGGATATGAATGCTTCATTCGA
ACAAACCCTGAGTATTCTGGATCAAGTGCATCAGGTCTCGTCGGAATTGTCAGAGTTTGCCGAAGAGCTGCAAAGCGCCA
CGTCTCAATTTAAGCTTTAA

Upstream 100 bases:

>100_bases
CTATATTGATAGTAGTCAGGTAAATGGCTCGGTAAAGGTGGTTGCTGAGTTCTAACTGGCGGTGCCGGCCCAGGTCGGCA
CCCCTTTCAAGGGGTTGTCT

Downstream 100 bases:

>100_bases
CGTTGAACCGCGGAAACAGAGGGTGGAGGTGCGCTTTTTAACACCAAGCGTACTCCACCCTCTGTCGTCTCTGTCCCAGC
CTGTGTGAAGGCACGCCTTG

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MTWFNNLPIFKKVGVIFIISVIIFAVNLAISLVSINKNRETLGFMEEKIYQRVELANQNLMLVQRLEEVYTQAVSFADED
LLEQAGSLHDNLAANLTLLQSSDIKETDTLRQMLSQLASYNQITSGLAKSMLDGTADMANIGAISQKKSAVYETLLGHVQ
QYKQAKVLEFKNTIKEAADRSQNSLWLTMVVGVVLLLFMAIVTISIARAISASAKGVAHSLGELADGKGDLRHQLPASSR
DELGQVSGNFNRFLGLLAGSIQRVVNVTSPLLNNAHDLKDKMETATGATQRQSHDAQTVQASMEEMRLSVIDISHNASQA
ADAAQIAEREAMDGMAVVQRTMDISLELNREIEHAANAINELAKDTESVSSILNVITSIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALASKTADATKEIREVLTRLKGAAESSVSTMTVAMSKSSENEEHAQKTGLALKTIQEQIVSINAMNTH
IARSTDEQSQVASRVVDNVVDMNASFEQTLSILDQVHQVSSELSEFAEELQSATSQFKL

Sequences:

>Translated_539_residues
MTWFNNLPIFKKVGVIFIISVIIFAVNLAISLVSINKNRETLGFMEEKIYQRVELANQNLMLVQRLEEVYTQAVSFADED
LLEQAGSLHDNLAANLTLLQSSDIKETDTLRQMLSQLASYNQITSGLAKSMLDGTADMANIGAISQKKSAVYETLLGHVQ
QYKQAKVLEFKNTIKEAADRSQNSLWLTMVVGVVLLLFMAIVTISIARAISASAKGVAHSLGELADGKGDLRHQLPASSR
DELGQVSGNFNRFLGLLAGSIQRVVNVTSPLLNNAHDLKDKMETATGATQRQSHDAQTVQASMEEMRLSVIDISHNASQA
ADAAQIAEREAMDGMAVVQRTMDISLELNREIEHAANAINELAKDTESVSSILNVITSIAEQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALASKTADATKEIREVLTRLKGAAESSVSTMTVAMSKSSENEEHAQKTGLALKTIQEQIVSINAMNTH
IARSTDEQSQVASRVVDNVVDMNASFEQTLSILDQVHQVSSELSEFAEELQSATSQFKL
>Mature_538_residues
TWFNNLPIFKKVGVIFIISVIIFAVNLAISLVSINKNRETLGFMEEKIYQRVELANQNLMLVQRLEEVYTQAVSFADEDL
LEQAGSLHDNLAANLTLLQSSDIKETDTLRQMLSQLASYNQITSGLAKSMLDGTADMANIGAISQKKSAVYETLLGHVQQ
YKQAKVLEFKNTIKEAADRSQNSLWLTMVVGVVLLLFMAIVTISIARAISASAKGVAHSLGELADGKGDLRHQLPASSRD
ELGQVSGNFNRFLGLLAGSIQRVVNVTSPLLNNAHDLKDKMETATGATQRQSHDAQTVQASMEEMRLSVIDISHNASQAA
DAAQIAEREAMDGMAVVQRTMDISLELNREIEHAANAINELAKDTESVSSILNVITSIAEQTNLLALNAAIEAARAGEQG
RGFAVVADEVRALASKTADATKEIREVLTRLKGAAESSVSTMTVAMSKSSENEEHAQKTGLALKTIQEQIVSINAMNTHI
ARSTDEQSQVASRVVDNVVDMNASFEQTLSILDQVHQVSSELSEFAEELQSATSQFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=379, Percent_Identity=29.287598944591, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI2367378, Length=325, Percent_Identity=28.3076923076923, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788195, Length=405, Percent_Identity=28.3950617283951, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788194, Length=389, Percent_Identity=28.0205655526992, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1789453, Length=357, Percent_Identity=30.5322128851541, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58560; Mature: 58429

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWFNNLPIFKKVGVIFIISVIIFAVNLAISLVSINKNRETLGFMEEKIYQRVELANQNL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
MLVQRLEEVYTQAVSFADEDLLEQAGSLHDNLAANLTLLQSSDIKETDTLRQMLSQLASY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHH
NQITSGLAKSMLDGTADMANIGAISQKKSAVYETLLGHVQQYKQAKVLEFKNTIKEAADR
HHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SQNSLWLTMVVGVVLLLFMAIVTISIARAISASAKGVAHSLGELADGKGDLRHQLPASSR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCH
DELGQVSGNFNRFLGLLAGSIQRVVNVTSPLLNNAHDLKDKMETATGATQRQSHDAQTVQ
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
ASMEEMRLSVIDISHNASQAADAAQIAEREAMDGMAVVQRTMDISLELNREIEHAANAIN
HHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELAKDTESVSSILNVITSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHH
ATKEIREVLTRLKGAAESSVSTMTVAMSKSSENEEHAQKTGLALKTIQEQIVSINAMNTH
HHHHHHHHHHHHHCCHHCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IARSTDEQSQVASRVVDNVVDMNASFEQTLSILDQVHQVSSELSEFAEELQSATSQFKL
HHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TWFNNLPIFKKVGVIFIISVIIFAVNLAISLVSINKNRETLGFMEEKIYQRVELANQNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCH
MLVQRLEEVYTQAVSFADEDLLEQAGSLHDNLAANLTLLQSSDIKETDTLRQMLSQLASY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHH
NQITSGLAKSMLDGTADMANIGAISQKKSAVYETLLGHVQQYKQAKVLEFKNTIKEAADR
HHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SQNSLWLTMVVGVVLLLFMAIVTISIARAISASAKGVAHSLGELADGKGDLRHQLPASSR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCH
DELGQVSGNFNRFLGLLAGSIQRVVNVTSPLLNNAHDLKDKMETATGATQRQSHDAQTVQ
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
ASMEEMRLSVIDISHNASQAADAAQIAEREAMDGMAVVQRTMDISLELNREIEHAANAIN
HHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELAKDTESVSSILNVITSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASKTAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHH
ATKEIREVLTRLKGAAESSVSTMTVAMSKSSENEEHAQKTGLALKTIQEQIVSINAMNTH
HHHHHHHHHHHHHCCHHCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IARSTDEQSQVASRVVDNVVDMNASFEQTLSILDQVHQVSSELSEFAEELQSATSQFKL
HHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]