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The map label for this gene is hlyB [H]

Identifier: 119773690

GI number: 119773690

Start: 676060

End: 677616

Strand: Direct

Name: hlyB [H]

Synonym: Sama_0550

Alternate gene names: 119773690

Gene position: 676060-677616 (Clockwise)

Preceding gene: 119773688

Following gene: 119773691

Centisome position: 15.7

GC content: 54.21

Gene sequence:

>1557_bases
ATGCTGTTTGAAAACAAGATGTTCCAACGACTGGGCTGGCTGTTGCTGTTGGTTGTATTGGTGCTGTTGTTGACCAAATC
CCTGTGGCTTGAAGCCATGGTGCTGCTGCTCGCGGCAGTTATCATTGGCACAGGCCTTATGGGGCAGGCCAAAGCCCTGG
CGGGTTTGGAGAGCGGGGTAGCCAACCTTGCCGACGGTGATTTGACACAGAGATTTGATGGTCATGTCAGTGATAACTAT
GCGAAGGTCGCCAAAGGGTTGCGGCGCATGAGCGAAGATGTGACCCGGACCGTGTCGGGGCTTTCGGATACCAGCGAGGC
GATGAATCAGGTTGCCAGAGAGCTGAAGTCAGTCAGTGAGCTTGCTACCTTGGGCGTGGCCTCGCAGAAACAGCGTACCG
AAGAGGCAGCAGCCTCCATGGCGCAAATGGTGCACACGGTGCAGGATATTTCTGCCAGTGCTGCACGTGTTGCGGCATCG
GTCGACGACACCATGGGGCGCGCCGAACATGGTGGTCGGCTGGTCAATCAGGCGGTGGGTCGCATCAATTCGATGGCCGA
GCAAATCAGTCAGAGTGAAATTGTTATCGAACAGCTGGCGCAGGATGCTGCCAGCATCAGCAGCATTATCGACACCATTT
CTCAGGTTGCTGAGCAAACCAACTTACTGGCACTTAATGCAGCTATTGAGAGTGCCAGAGCCGGCGAACACGGTCGCGGC
TTTGCTGTGGTGGCAGATGAAGTGCGCAATCTGGCCAAACGTACCTCGGAAGCGACGGTGGAAATCCAGCAGCAAATACA
GGCGCTGCAAGCAGGAAGCCGTAACGGTGTGGCCGTGATGCATGCCTCTGTGGCGCTTGCGGAAGAAACCAGGGGACTGG
TGAGTCAGGCCAGTGAAGCGCTCACTGTGATAGTGACGCAGGTTGGCGAGATAACCCAGATGAGCCATCAAATCGCTGCT
GCGTCTGAACATCAGCAGCAAGTGGCCGAGCAAATCAACGAATCCATTGCCTCTATCTCCCACCAGGCAACCGAAAATGC
CGCCAACACCAATCGCAACAATCTCGCCAGTCTTAAACTTTTCAACATGTCTCAGGAAATTGGTTCCCTGCTGCACAGAT
TTCATGTGGACAAGAGTCGTATTCGCCATGAGAACGCCTTTGTCAGTTGGGGACCATCCCTCGACATTGGTATGGCCGAA
GTCAATCGCCAACATCAGCGACTCATTACCCTGATAAACGAGCTGCACAGGGCCATCAACGAAGGTTATGGTCTGGCGGC
AATCAAGCGTATTGTGCAGGGGCTGGTGGACTACACCGCCAATCATTTCAGTTACGAAGAAGAGTTGTTCGCGCGCTTTG
ATTACCCCCAGAGTCAGGACCACGAAGATGAGCACAAGAAATTGGTCACTCAAGTCCTCGACTTTCAGCGTCGGGTGGGA
CGGGGAGAAAACGTCTCGGATGAGCTGATGGCGTTTCTCAAGGCCTGGCTTATCAACCACATTCAGGGCAGCGATAAGCA
ATATGCCCCATATCTGATTGCCAATGGGGCTGACTAA

Upstream 100 bases:

>100_bases
ATTTTGAGAGCCTGGACCATAATTGCTGTTGGGATGAACAGACAAACTGCCGGGCTCCCCCTCTTTTTGGGTAGTCGGGT
GGTGAGCTTGAGGGATGCCA

Downstream 100 bases:

>100_bases
CTGTGTATTAAACACCGTTTTTAGTTGCAGCAAATGAGATTGAAATTTGGACAATTTCGTACAATTTGTGGTTAAGCGAA
TTCTCAGTAGTTGTCGTAAT

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLFENKMFQRLGWLLLLVVLVLLLTKSLWLEAMVLLLAAVIIGTGLMGQAKALAGLESGVANLADGDLTQRFDGHVSDNY
AKVAKGLRRMSEDVTRTVSGLSDTSEAMNQVARELKSVSELATLGVASQKQRTEEAAASMAQMVHTVQDISASAARVAAS
VDDTMGRAEHGGRLVNQAVGRINSMAEQISQSEIVIEQLAQDAASISSIIDTISQVAEQTNLLALNAAIESARAGEHGRG
FAVVADEVRNLAKRTSEATVEIQQQIQALQAGSRNGVAVMHASVALAEETRGLVSQASEALTVIVTQVGEITQMSHQIAA
ASEHQQQVAEQINESIASISHQATENAANTNRNNLASLKLFNMSQEIGSLLHRFHVDKSRIRHENAFVSWGPSLDIGMAE
VNRQHQRLITLINELHRAINEGYGLAAIKRIVQGLVDYTANHFSYEEELFARFDYPQSQDHEDEHKKLVTQVLDFQRRVG
RGENVSDELMAFLKAWLINHIQGSDKQYAPYLIANGAD

Sequences:

>Translated_518_residues
MLFENKMFQRLGWLLLLVVLVLLLTKSLWLEAMVLLLAAVIIGTGLMGQAKALAGLESGVANLADGDLTQRFDGHVSDNY
AKVAKGLRRMSEDVTRTVSGLSDTSEAMNQVARELKSVSELATLGVASQKQRTEEAAASMAQMVHTVQDISASAARVAAS
VDDTMGRAEHGGRLVNQAVGRINSMAEQISQSEIVIEQLAQDAASISSIIDTISQVAEQTNLLALNAAIESARAGEHGRG
FAVVADEVRNLAKRTSEATVEIQQQIQALQAGSRNGVAVMHASVALAEETRGLVSQASEALTVIVTQVGEITQMSHQIAA
ASEHQQQVAEQINESIASISHQATENAANTNRNNLASLKLFNMSQEIGSLLHRFHVDKSRIRHENAFVSWGPSLDIGMAE
VNRQHQRLITLINELHRAINEGYGLAAIKRIVQGLVDYTANHFSYEEELFARFDYPQSQDHEDEHKKLVTQVLDFQRRVG
RGENVSDELMAFLKAWLINHIQGSDKQYAPYLIANGAD
>Mature_518_residues
MLFENKMFQRLGWLLLLVVLVLLLTKSLWLEAMVLLLAAVIIGTGLMGQAKALAGLESGVANLADGDLTQRFDGHVSDNY
AKVAKGLRRMSEDVTRTVSGLSDTSEAMNQVARELKSVSELATLGVASQKQRTEEAAASMAQMVHTVQDISASAARVAAS
VDDTMGRAEHGGRLVNQAVGRINSMAEQISQSEIVIEQLAQDAASISSIIDTISQVAEQTNLLALNAAIESARAGEHGRG
FAVVADEVRNLAKRTSEATVEIQQQIQALQAGSRNGVAVMHASVALAEETRGLVSQASEALTVIVTQVGEITQMSHQIAA
ASEHQQQVAEQINESIASISHQATENAANTNRNNLASLKLFNMSQEIGSLLHRFHVDKSRIRHENAFVSWGPSLDIGMAE
VNRQHQRLITLINELHRAINEGYGLAAIKRIVQGLVDYTANHFSYEEELFARFDYPQSQDHEDEHKKLVTQVLDFQRRVG
RGENVSDELMAFLKAWLINHIQGSDKQYAPYLIANGAD

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=346, Percent_Identity=30.3468208092486, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=32.7814569536424, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788194, Length=397, Percent_Identity=27.7078085642317, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1787690, Length=375, Percent_Identity=26.9333333333333, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789453, Length=218, Percent_Identity=32.1100917431193, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 56443; Mature: 56443

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50885 HAMP ; PS00550 HEMERYTHRINS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFENKMFQRLGWLLLLVVLVLLLTKSLWLEAMVLLLAAVIIGTGLMGQAKALAGLESGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ANLADGDLTQRFDGHVSDNYAKVAKGLRRMSEDVTRTVSGLSDTSEAMNQVARELKSVSE
HHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LATLGVASQKQRTEEAAASMAQMVHTVQDISASAARVAASVDDTMGRAEHGGRLVNQAVG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
RINSMAEQISQSEIVIEQLAQDAASISSIIDTISQVAEQTNLLALNAAIESARAGEHGRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FAVVADEVRNLAKRTSEATVEIQQQIQALQAGSRNGVAVMHASVALAEETRGLVSQASEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LTVIVTQVGEITQMSHQIAAASEHQQQVAEQINESIASISHQATENAANTNRNNLASLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FNMSQEIGSLLHRFHVDKSRIRHENAFVSWGPSLDIGMAEVNRQHQRLITLINELHRAIN
HHHHHHHHHHHHHHHCCHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGYGLAAIKRIVQGLVDYTANHFSYEEELFARFDYPQSQDHEDEHKKLVTQVLDFQRRVG
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCC
RGENVSDELMAFLKAWLINHIQGSDKQYAPYLIANGAD
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCC
>Mature Secondary Structure
MLFENKMFQRLGWLLLLVVLVLLLTKSLWLEAMVLLLAAVIIGTGLMGQAKALAGLESGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ANLADGDLTQRFDGHVSDNYAKVAKGLRRMSEDVTRTVSGLSDTSEAMNQVARELKSVSE
HHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LATLGVASQKQRTEEAAASMAQMVHTVQDISASAARVAASVDDTMGRAEHGGRLVNQAVG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
RINSMAEQISQSEIVIEQLAQDAASISSIIDTISQVAEQTNLLALNAAIESARAGEHGRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FAVVADEVRNLAKRTSEATVEIQQQIQALQAGSRNGVAVMHASVALAEETRGLVSQASEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LTVIVTQVGEITQMSHQIAAASEHQQQVAEQINESIASISHQATENAANTNRNNLASLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
FNMSQEIGSLLHRFHVDKSRIRHENAFVSWGPSLDIGMAEVNRQHQRLITLINELHRAIN
HHHHHHHHHHHHHHHCCHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGYGLAAIKRIVQGLVDYTANHFSYEEELFARFDYPQSQDHEDEHKKLVTQVLDFQRRVG
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCC
RGENVSDELMAFLKAWLINHIQGSDKQYAPYLIANGAD
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]