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The map label for this gene is scoA [H]

Identifier: 119773658

GI number: 119773658

Start: 637904

End: 638665

Strand: Direct

Name: scoA [H]

Synonym: Sama_0518

Alternate gene names: 119773658

Gene position: 637904-638665 (Clockwise)

Preceding gene: 119773656

Following gene: 119773659

Centisome position: 14.81

GC content: 52.89

Gene sequence:

>762_bases
TTGGGTGATAGTAAGCGCCACACATCACCGAGGGTAAGAGAGCAGATTGTGGCGGGATTGAATAAGGTCGTTACCAGTTA
CGCACAGGCGTTGGCCGGACTCGAAGACGGGATGACAGTGATAGCCGGAGGCTTTGGCCTTTGCGGTATCCCTGAAAATC
TCATCAAAGAAATCAAACGCAAGGGCACGCGAAACCTCACCGTGGTGTCAAACAACTGCGGCACAACCGAATACGGCCTT
GGCATTTTGCTTCTGGATAAACAAATCAAGAAGATGGTGGCCTCTTACGTGGGAGAAAATACCAACTTTGAAGCGCAAAT
GATGTCGGGCGAACTGGAAGTTGAGCTGACACCCCAGGGCACACTGGCGGAAAAAATGCGTGCAGCCGGTGCCGGTATAC
CGGCTTTTTACACGGCAACGGGCTTTGGCACAGAGGTGGCCGTGGGCAAGGAAGTGAAGGAATTCAATGGCCGGCAGTAC
ATTCTCGAGGAGTCCATCAAGGGCGACTTTGCCCTGGTCAAAGCCTGGAAAGCCGATACCTATGGCAACCTGGTATTTCG
TAAAACAGCGCGTAATTTCAATCCTTTGGCAGCCATGGCTGGCAAGATAACTGTGGTGGAAGTGGAACAAATTGTCGCGC
CCGGCGAGCTGGATCCCGATGAAATCCATACCCCAGGCATTTACGTCGACAGGCTGATCCAGGGCAGTTTCGAGAAGCGC
ATCGAGCAGCTCACCATCCGTCCCTCTTCACACGGTAAATAG

Upstream 100 bases:

>100_bases
CGGGCGCCCGGGCCGGCAGACTTGCGATTGATGCCCCCAGAATAGAGCAACAGGCCCGGCATTTATTTGGGACCTTAGTA
CCATAGGCCGACCCTGAAAA

Downstream 100 bases:

>100_bases
GAGTTCACCATGGCACTTTCCAGAGAACAACTCGCCCAGCGTGTCGCACAGGAACTCAAGGACGGCTATTACGTCAACCT
CGGCATAGGCATTCCCACCC

Product: 3-oxoacid CoA-transferase

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MGDSKRHTSPRVREQIVAGLNKVVTSYAQALAGLEDGMTVIAGGFGLCGIPENLIKEIKRKGTRNLTVVSNNCGTTEYGL
GILLLDKQIKKMVASYVGENTNFEAQMMSGELEVELTPQGTLAEKMRAAGAGIPAFYTATGFGTEVAVGKEVKEFNGRQY
ILEESIKGDFALVKAWKADTYGNLVFRKTARNFNPLAAMAGKITVVEVEQIVAPGELDPDEIHTPGIYVDRLIQGSFEKR
IEQLTIRPSSHGK

Sequences:

>Translated_253_residues
MGDSKRHTSPRVREQIVAGLNKVVTSYAQALAGLEDGMTVIAGGFGLCGIPENLIKEIKRKGTRNLTVVSNNCGTTEYGL
GILLLDKQIKKMVASYVGENTNFEAQMMSGELEVELTPQGTLAEKMRAAGAGIPAFYTATGFGTEVAVGKEVKEFNGRQY
ILEESIKGDFALVKAWKADTYGNLVFRKTARNFNPLAAMAGKITVVEVEQIVAPGELDPDEIHTPGIYVDRLIQGSFEKR
IEQLTIRPSSHGK
>Mature_252_residues
GDSKRHTSPRVREQIVAGLNKVVTSYAQALAGLEDGMTVIAGGFGLCGIPENLIKEIKRKGTRNLTVVSNNCGTTEYGLG
ILLLDKQIKKMVASYVGENTNFEAQMMSGELEVELTPQGTLAEKMRAAGAGIPAFYTATGFGTEVAVGKEVKEFNGRQYI
LEESIKGDFALVKAWKADTYGNLVFRKTARNFNPLAAMAGKITVVEVEQIVAPGELDPDEIHTPGIYVDRLIQGSFEKRI
EQLTIRPSSHGK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=251, Percent_Identity=56.9721115537849, Blast_Score=280, Evalue=7e-76,
Organism=Homo sapiens, GI11545841, Length=258, Percent_Identity=51.937984496124, Blast_Score=251, Evalue=5e-67,
Organism=Escherichia coli, GI1788551, Length=200, Percent_Identity=42.5, Blast_Score=186, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=51.440329218107, Blast_Score=254, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24655794, Length=244, Percent_Identity=54.0983606557377, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI21358325, Length=244, Percent_Identity=54.0983606557377, Blast_Score=257, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 27454; Mature: 27323

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDSKRHTSPRVREQIVAGLNKVVTSYAQALAGLEDGMTVIAGGFGLCGIPENLIKEIKR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCEEEECCCCCCCCCHHHHHHHHH
KGTRNLTVVSNNCGTTEYGLGILLLDKQIKKMVASYVGENTNFEAQMMSGELEVELTPQG
CCCCEEEEEECCCCCHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCC
TLAEKMRAAGAGIPAFYTATGFGTEVAVGKEVKEFNGRQYILEESIKGDFALVKAWKADT
HHHHHHHHHCCCCCCEEEECCCCCHHHHCHHHHHCCCCEEEEHHHCCCCEEEEEEECCCC
YGNLVFRKTARNFNPLAAMAGKITVVEVEQIVAPGELDPDEIHTPGIYVDRLIQGSFEKR
CCCEEEEECCCCCCHHHHHHCCEEEEEHHHHHCCCCCCHHHCCCCCHHHHHHHHCHHHHH
IEQLTIRPSSHGK
HHHEECCCCCCCC
>Mature Secondary Structure 
GDSKRHTSPRVREQIVAGLNKVVTSYAQALAGLEDGMTVIAGGFGLCGIPENLIKEIKR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCEEEECCCCCCCCCHHHHHHHHH
KGTRNLTVVSNNCGTTEYGLGILLLDKQIKKMVASYVGENTNFEAQMMSGELEVELTPQG
CCCCEEEEEECCCCCHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCC
TLAEKMRAAGAGIPAFYTATGFGTEVAVGKEVKEFNGRQYILEESIKGDFALVKAWKADT
HHHHHHHHHCCCCCCEEEECCCCCHHHHCHHHHHCCCCEEEEHHHCCCCEEEEEEECCCC
YGNLVFRKTARNFNPLAAMAGKITVVEVEQIVAPGELDPDEIHTPGIYVDRLIQGSFEKR
CCCEEEEECCCCCCHHHHHHCCEEEEEHHHHHCCCCCCHHHCCCCCHHHHHHHHCHHHHH
IEQLTIRPSSHGK
HHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]