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The map label for this gene is gap3 [H]

Identifier: 119773634

GI number: 119773634

Start: 606705

End: 607718

Strand: Direct

Name: gap3 [H]

Synonym: Sama_0494

Alternate gene names: 119773634

Gene position: 606705-607718 (Clockwise)

Preceding gene: 119773633

Following gene: 119773635

Centisome position: 14.09

GC content: 55.92

Gene sequence:

>1014_bases
ATGAGTAAGATTAAAGTAGGTATCAACGGTTTTGGCCGCATGGGGCGCCTCACGCTACGCTCAGCCTGGGGCAATGATGC
GTTTGAATTTGTACATATCAATGACCCCGCGGGGGATGCGACCTCGCTGGCGCACCTGTTGGAATTTGATTCTGTGCATG
GCCGCTGGCAGCATCCGGTGGCGAGCGATGGCTGCAATATTCTGATTGGTGACAAGCGAATCAGCACCAGTATGAACAAG
ACCATTGAAGACACCGATTGGTCGGGCTGTGATCTGGTGATTGAAGCCTCCGGCAAGATGAAAACCAAGGCAGTGCTCCA
AGCCTATCTTGCTCAGGGCGTTAAGCGGGTCGTGGTGACGGCACCTGTGAAGGAAGAAGGCGTGCTTAACGTGGTGATGG
GGATTAACCACGAACTGTATAACCCGGATGTGCACCCGATAGTTACTGCGGCTTCCTGCACCACCAACTGCCTGGCACCC
GTGGTCAAGGTTATCCATGAAGGCCTGGGTATCAAGCATGGCTCCATGACCACCATTCATGACATCACCAACACCCAAAC
CATCCTGGATGCGCCTCACAAGGATCTGCGACGCGCCCGTGCCTGTGGTATGAGCCTTATTCCCACGACCACAGGCAGCG
CCACCGCCATTACCCATATTTTCCCCGAGCTCAAGGGGCGTCTGAACGGCCACGCAGTGAGGGTGCCGCTGGCCAATGCC
TCGCTGACCGACTGCGTGTTTGAGGTGGAGCGCCCCACCACTGAGGTGGAGGTGAATGCACTGCTCAAGGCCGCCGCAGA
AGGCGAACTCAAGGGTATTTTGGGATTTGAAGAGCGACCACTGGTGTCCATTGATTACCGCACAGATCCTCGCTCCAGCA
TCATAGATGCCCTGTCCACCATGGTGGTGAACGGCACCCAGGTAAAGCTATATTGCTGGTACGATAACGAATGGGGTTAT
GCCAACCGGGTAGCGGAACTGGCGCTGATGGTGGGCCGGATGGATAAGGCTTGA

Upstream 100 bases:

>100_bases
GACCAGACTGGCTGGCCGATGAAAAACAACGCTTGACGACCATGGGTTGCAGACCCGGACGCTGCTGTTAATGGCGTGTC
TGACAGGAAAAGAGGGCAAG

Downstream 100 bases:

>100_bases
ACTCATGTTTGCCAGACGCCATGAACTGACGCCCGGGCAGCGCCAATACCTGTTGGTGACTGCCAACTATTGGGCGTTTA
CCCTCACCGATGGTGCGCTG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSKIKVGINGFGRMGRLTLRSAWGNDAFEFVHINDPAGDATSLAHLLEFDSVHGRWQHPVASDGCNILIGDKRISTSMNK
TIEDTDWSGCDLVIEASGKMKTKAVLQAYLAQGVKRVVVTAPVKEEGVLNVVMGINHELYNPDVHPIVTAASCTTNCLAP
VVKVIHEGLGIKHGSMTTIHDITNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITHIFPELKGRLNGHAVRVPLANA
SLTDCVFEVERPTTEVEVNALLKAAAEGELKGILGFEERPLVSIDYRTDPRSSIIDALSTMVVNGTQVKLYCWYDNEWGY
ANRVAELALMVGRMDKA

Sequences:

>Translated_337_residues
MSKIKVGINGFGRMGRLTLRSAWGNDAFEFVHINDPAGDATSLAHLLEFDSVHGRWQHPVASDGCNILIGDKRISTSMNK
TIEDTDWSGCDLVIEASGKMKTKAVLQAYLAQGVKRVVVTAPVKEEGVLNVVMGINHELYNPDVHPIVTAASCTTNCLAP
VVKVIHEGLGIKHGSMTTIHDITNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITHIFPELKGRLNGHAVRVPLANA
SLTDCVFEVERPTTEVEVNALLKAAAEGELKGILGFEERPLVSIDYRTDPRSSIIDALSTMVVNGTQVKLYCWYDNEWGY
ANRVAELALMVGRMDKA
>Mature_336_residues
SKIKVGINGFGRMGRLTLRSAWGNDAFEFVHINDPAGDATSLAHLLEFDSVHGRWQHPVASDGCNILIGDKRISTSMNKT
IEDTDWSGCDLVIEASGKMKTKAVLQAYLAQGVKRVVVTAPVKEEGVLNVVMGINHELYNPDVHPIVTAASCTTNCLAPV
VKVIHEGLGIKHGSMTTIHDITNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITHIFPELKGRLNGHAVRVPLANAS
LTDCVFEVERPTTEVEVNALLKAAAEGELKGILGFEERPLVSIDYRTDPRSSIIDALSTMVVNGTQVKLYCWYDNEWGYA
NRVAELALMVGRMDKA

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=330, Percent_Identity=41.2121212121212, Blast_Score=268, Evalue=7e-72,
Organism=Homo sapiens, GI7657116, Length=337, Percent_Identity=39.1691394658754, Blast_Score=246, Evalue=2e-65,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=41.5902140672783, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1789295, Length=331, Percent_Identity=38.6706948640483, Blast_Score=241, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=41.1940298507463, Blast_Score=268, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=40.5970149253731, Blast_Score=265, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=40.8955223880597, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17568413, Length=335, Percent_Identity=40.8955223880597, Blast_Score=263, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=41.4414414414414, Blast_Score=266, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=40.8408408408408, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=40.2402402402402, Blast_Score=260, Evalue=2e-70,
Organism=Drosophila melanogaster, GI19922412, Length=336, Percent_Identity=39.2857142857143, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=39.5705521472393, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=39.5705521472393, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=39.2638036809816, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=39.2638036809816, Blast_Score=248, Evalue=6e-66,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36625; Mature: 36494

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIKVGINGFGRMGRLTLRSAWGNDAFEFVHINDPAGDATSLAHLLEFDSVHGRWQHPV
CCEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
ASDGCNILIGDKRISTSMNKTIEDTDWSGCDLVIEASGKMKTKAVLQAYLAQGVKRVVVT
CCCCCEEEECCCCHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEE
APVKEEGVLNVVMGINHELYNPDVHPIVTAASCTTNCLAPVVKVIHEGLGIKHGSMTTIH
CCCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
DITNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITHIFPELKGRLNGHAVRVPLANA
ECCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCC
SLTDCVFEVERPTTEVEVNALLKAAAEGELKGILGFEERPLVSIDYRTDPRSSIIDALST
CHHHHEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHH
MVVNGTQVKLYCWYDNEWGYANRVAELALMVGRMDKA
HEECCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKIKVGINGFGRMGRLTLRSAWGNDAFEFVHINDPAGDATSLAHLLEFDSVHGRWQHPV
CEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
ASDGCNILIGDKRISTSMNKTIEDTDWSGCDLVIEASGKMKTKAVLQAYLAQGVKRVVVT
CCCCCEEEECCCCHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEE
APVKEEGVLNVVMGINHELYNPDVHPIVTAASCTTNCLAPVVKVIHEGLGIKHGSMTTIH
CCCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
DITNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITHIFPELKGRLNGHAVRVPLANA
ECCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCC
SLTDCVFEVERPTTEVEVNALLKAAAEGELKGILGFEERPLVSIDYRTDPRSSIIDALST
CHHHHEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHH
MVVNGTQVKLYCWYDNEWGYANRVAELALMVGRMDKA
HEECCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]