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The map label for this gene is arsR [H]

Identifier: 119773633

GI number: 119773633

Start: 606322

End: 606675

Strand: Direct

Name: arsR [H]

Synonym: Sama_0493

Alternate gene names: 119773633

Gene position: 606322-606675 (Clockwise)

Preceding gene: 119773628

Following gene: 119773634

Centisome position: 14.08

GC content: 55.65

Gene sequence:

>354_bases
ATGCCAGAGGAGGCGGCGATGGACGTAGTGAGCTTTTTCAAAGCGCTGGCCGATGATACCCGGCTTAGAATCCTTATGCT
GATTGTGGGGGAAACCGAGCTTTGTGTCTGTGAGCTGACGGAGGCGCTTAATCTCAGTCAGCCCAAGATCTCACGCCATT
TACGTCTTTTAAAAGACGCAGGCTTGCTGACAGACAGGCGTCAGGGGCAGTGGGTGTACTACCGCCAGGCCGAGGACTTG
CCACTGTGGTGTGCCGGGCAACTGGCACATTTGGCACAGAAAGGACCAGACTGGCTGGCCGATGAAAAACAACGCTTGAC
GACCATGGGTTGCAGACCCGGACGCTGCTGTTAA

Upstream 100 bases:

>100_bases
GTGTCTGTCCAGGTATGTGTGGACAATTACGCGGGGGCACGGCCTGACATAAAAGTGTAATTTTACACATATGGAATTTC
ATATATGATGGTGACCATAC

Downstream 100 bases:

>100_bases
TGGCGTGTCTGACAGGAAAAGAGGGCAAGATGAGTAAGATTAAAGTAGGTATCAACGGTTTTGGCCGCATGGGGCGCCTC
ACGCTACGCTCAGCCTGGGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MPEEAAMDVVSFFKALADDTRLRILMLIVGETELCVCELTEALNLSQPKISRHLRLLKDAGLLTDRRQGQWVYYRQAEDL
PLWCAGQLAHLAQKGPDWLADEKQRLTTMGCRPGRCC

Sequences:

>Translated_117_residues
MPEEAAMDVVSFFKALADDTRLRILMLIVGETELCVCELTEALNLSQPKISRHLRLLKDAGLLTDRRQGQWVYYRQAEDL
PLWCAGQLAHLAQKGPDWLADEKQRLTTMGCRPGRCC
>Mature_116_residues
PEEAAMDVVSFFKALADDTRLRILMLIVGETELCVCELTEALNLSQPKISRHLRLLKDAGLLTDRRQGQWVYYRQAEDLP
LWCAGQLAHLAQKGPDWLADEKQRLTTMGCRPGRCC

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=76, Percent_Identity=56.578947368421, Blast_Score=92, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13303; Mature: 13171

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEEAAMDVVSFFKALADDTRLRILMLIVGETELCVCELTEALNLSQPKISRHLRLLKDA
CCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GLLTDRRQGQWVYYRQAEDLPLWCAGQLAHLAQKGPDWLADEKQRLTTMGCRPGRCC
CCCCCCCCCCEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PEEAAMDVVSFFKALADDTRLRILMLIVGETELCVCELTEALNLSQPKISRHLRLLKDA
CHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GLLTDRRQGQWVYYRQAEDLPLWCAGQLAHLAQKGPDWLADEKQRLTTMGCRPGRCC
CCCCCCCCCCEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]