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The map label for this gene is coaE [H]

Identifier: 119773507

GI number: 119773507

Start: 443317

End: 443934

Strand: Reverse

Name: coaE [H]

Synonym: Sama_0366

Alternate gene names: 119773507

Gene position: 443934-443317 (Counterclockwise)

Preceding gene: 119773508

Following gene: 119773506

Centisome position: 10.31

GC content: 48.71

Gene sequence:

>618_bases
ATGGCCGAGTTTATTCTGGGCCTCACCGGCGGAATCGGTAGCGGCAAGACAACTGTTGCTAACCTCTTTCACGAACAAGG
CATTGAACTGGTTGATGCCGATGTTATCGCCCGTGAAGTGGTCGAGTACGGTTCAGTTGGGCTCAAGGCGATTGAAGACC
ACTTCGGTAGTGACATTCTCCAAGCCGATGGCAGTCTCGATCGTGCCAAGCTGAGAGAGCGGATTTTTACCGATGAATCT
GAGCGGCTCTGGCTGAACAACTTACTTCACCCCATGATTCGCCAAACCATGCTGTCGTCTGCAAAAAATGCTGATTCAGA
TTATGTTATTTTGGTTGTGCCCTTGCTATTTGAGAATGGGTTGGATAGCTTAGTTGATCGAACTTTGGTGGTTGATATTT
CACCTGATTTACAAATCCAACGCACCGTCGAACGAGATAACGTGAGCGAGGCCCAAATCGCCAACATTATCGCCAGCCAA
ATCAGCCGTGAAGAGAGGCTGCAAAAAGCCGACGACATTATAGACAACAGAGGAGAGATAGCCGACCTTAAGGAGCAGGT
TAATAGGCTCCACCAGTATTATTTAGCACTGGCGGCATCAAAAGCACCGCATGACTGA

Upstream 100 bases:

>100_bases
GTGAAAATCCCATCCCATTTGGTCCCTATATCGCGGCCGCTGGCTGGATAGCACTTATTTGGGGACAAGATATTGTCAGC
TGGTATCTGGGTTCTCTTTG

Downstream 100 bases:

>100_bases
ACTGATATATGAGCAACCTCTGAACGAAAAAATCCGCAGCTATCTGCGGCTCGAATATCTCGCCCAGCAGGTGCAACATA
ATCTGGAAAACGACCATCAG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MAEFILGLTGGIGSGKTTVANLFHEQGIELVDADVIAREVVEYGSVGLKAIEDHFGSDILQADGSLDRAKLRERIFTDES
ERLWLNNLLHPMIRQTMLSSAKNADSDYVILVVPLLFENGLDSLVDRTLVVDISPDLQIQRTVERDNVSEAQIANIIASQ
ISREERLQKADDIIDNRGEIADLKEQVNRLHQYYLALAASKAPHD

Sequences:

>Translated_205_residues
MAEFILGLTGGIGSGKTTVANLFHEQGIELVDADVIAREVVEYGSVGLKAIEDHFGSDILQADGSLDRAKLRERIFTDES
ERLWLNNLLHPMIRQTMLSSAKNADSDYVILVVPLLFENGLDSLVDRTLVVDISPDLQIQRTVERDNVSEAQIANIIASQ
ISREERLQKADDIIDNRGEIADLKEQVNRLHQYYLALAASKAPHD
>Mature_204_residues
AEFILGLTGGIGSGKTTVANLFHEQGIELVDADVIAREVVEYGSVGLKAIEDHFGSDILQADGSLDRAKLRERIFTDESE
RLWLNNLLHPMIRQTMLSSAKNADSDYVILVVPLLFENGLDSLVDRTLVVDISPDLQIQRTVERDNVSEAQIANIIASQI
SREERLQKADDIIDNRGEIADLKEQVNRLHQYYLALAASKAPHD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=192, Percent_Identity=34.8958333333333, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI191252795, Length=192, Percent_Identity=34.8958333333333, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI205277394, Length=190, Percent_Identity=26.8421052631579, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227607, Length=189, Percent_Identity=25.3968253968254, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227605, Length=190, Percent_Identity=26.8421052631579, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227603, Length=190, Percent_Identity=26.8421052631579, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227601, Length=190, Percent_Identity=26.8421052631579, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786292, Length=196, Percent_Identity=52.0408163265306, Blast_Score=209, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17554944, Length=191, Percent_Identity=34.5549738219895, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25143409, Length=189, Percent_Identity=29.6296296296296, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=195, Percent_Identity=36.4102564102564, Blast_Score=108, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24644728, Length=183, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24658602, Length=192, Percent_Identity=28.6458333333333, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977
- InterPro:   IPR000764 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22793; Mature: 22662

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFILGLTGGIGSGKTTVANLFHEQGIELVDADVIAREVVEYGSVGLKAIEDHFGSDIL
CCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHH
QADGSLDRAKLRERIFTDESERLWLNNLLHPMIRQTMLSSAKNADSDYVILVVPLLFENG
HCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCC
LDSLVDRTLVVDISPDLQIQRTVERDNVSEAQIANIIASQISREERLQKADDIIDNRGEI
HHHHHCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ADLKEQVNRLHQYYLALAASKAPHD
HHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AEFILGLTGGIGSGKTTVANLFHEQGIELVDADVIAREVVEYGSVGLKAIEDHFGSDIL
CCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHH
QADGSLDRAKLRERIFTDESERLWLNNLLHPMIRQTMLSSAKNADSDYVILVVPLLFENG
HCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCC
LDSLVDRTLVVDISPDLQIQRTVERDNVSEAQIANIIASQISREERLQKADDIIDNRGEI
HHHHHCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ADLKEQVNRLHQYYLALAASKAPHD
HHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]