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The map label for this gene is ccmB [H]

Identifier: 119773385

GI number: 119773385

Start: 268044

End: 268730

Strand: Reverse

Name: ccmB [H]

Synonym: Sama_0244

Alternate gene names: 119773385

Gene position: 268730-268044 (Counterclockwise)

Preceding gene: 119773386

Following gene: 119773384

Centisome position: 6.24

GC content: 51.97

Gene sequence:

>687_bases
ATGAAAAGAGGCATTAGTTTTACCCAGGCATTTGGCACTGTACTCAAGCGGGATTTAAAAATTGCCATCCGTCATCGCGG
CGATATCTTCAATCCCTTGTTATTTTTTGTGATGGTCGTGACCCTGTTCCCATTGGGAATTGGCCCTGAACCACAGGTAT
TGACCCGCATTGCTCCCGGCATCATTTGGGTAGCTGCGCTGCTGGCGTCCATGTTATCGCTGGAGCGTTTGTTCAAAGCA
GACTTTGTCGATGGCTCGCTGGAGCAGATGCTGCTAAGTCCGCAGCCACTGTACATCACAGTGCTGGCCAAGGTGCTGGC
CCACTGGCTGTTAACCGGCGTGCCACTGATTTTGGTGTCGCCGCTGCTGGCGGTATTGCTGCATCTGGAAGACAACAGTT
ATGGTGCGCTGATGAGCACCCTGGCGCTGGGTACTCCGGTGCTGAGTCTGCTTGGTGCCATAGGTGTGGCACTGACGGTA
GGATTACGTAAAGGCGGCGTATTACTGAGTTTGTTAATACTGCCGCTCTATATTCCGGTACTGATTTTTGCGACCAGTGC
CATTGATGCAGCGGGAATGAATTTACCCTACGATGGCCAGCTCGCTATAATAGGTGCCATGCTGGTTGGGTCTTTAACAC
TGGCGCCCTTTGCCGTTGGCGCCTCTTTAAGAGTGAGTACTAACTAA

Upstream 100 bases:

>100_bases
GCTGTGTGATCCTGACGACTCACCAGGATATGGGACTCATCAAGGATGAGCGGCTTCGCAAACTCAAGCTTGAGTACAGG
TTCGTATAAGGTTGGCTCGC

Downstream 100 bases:

>100_bases
TATGTGGAAGTGGTTACATCCTTACGCCGATCCCGAGCGTGCTTACAAGTTATCAGACAAACTCTTACCCTGGTTTGCCT
TCCTGGCGTTAGCCTTTATC

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKRGISFTQAFGTVLKRDLKIAIRHRGDIFNPLLFFVMVVTLFPLGIGPEPQVLTRIAPGIIWVAALLASMLSLERLFKA
DFVDGSLEQMLLSPQPLYITVLAKVLAHWLLTGVPLILVSPLLAVLLHLEDNSYGALMSTLALGTPVLSLLGAIGVALTV
GLRKGGVLLSLLILPLYIPVLIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAVGASLRVSTN

Sequences:

>Translated_228_residues
MKRGISFTQAFGTVLKRDLKIAIRHRGDIFNPLLFFVMVVTLFPLGIGPEPQVLTRIAPGIIWVAALLASMLSLERLFKA
DFVDGSLEQMLLSPQPLYITVLAKVLAHWLLTGVPLILVSPLLAVLLHLEDNSYGALMSTLALGTPVLSLLGAIGVALTV
GLRKGGVLLSLLILPLYIPVLIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAVGASLRVSTN
>Mature_228_residues
MKRGISFTQAFGTVLKRDLKIAIRHRGDIFNPLLFFVMVVTLFPLGIGPEPQVLTRIAPGIIWVAALLASMLSLERLFKA
DFVDGSLEQMLLSPQPLYITVLAKVLAHWLLTGVPLILVSPLLAVLLHLEDNSYGALMSTLALGTPVLSLLGAIGVALTV
GLRKGGVLLSLLILPLYIPVLIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAVGASLRVSTN

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=218, Percent_Identity=61.0091743119266, Blast_Score=222, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 24189; Mature: 24189

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGISFTQAFGTVLKRDLKIAIRHRGDIFNPLLFFVMVVTLFPLGIGPEPQVLTRIAPG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IIWVAALLASMLSLERLFKADFVDGSLEQMLLSPQPLYITVLAKVLAHWLLTGVPLILVS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
PLLAVLLHLEDNSYGALMSTLALGTPVLSLLGAIGVALTVGLRKGGVLLSLLILPLYIPV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAVGASLRVSTN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure
MKRGISFTQAFGTVLKRDLKIAIRHRGDIFNPLLFFVMVVTLFPLGIGPEPQVLTRIAPG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IIWVAALLASMLSLERLFKADFVDGSLEQMLLSPQPLYITVLAKVLAHWLLTGVPLILVS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
PLLAVLLHLEDNSYGALMSTLALGTPVLSLLGAIGVALTVGLRKGGVLLSLLILPLYIPV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAVGASLRVSTN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]