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The map label for this gene is ribB [H]

Identifier: 119773285

GI number: 119773285

Start: 164603

End: 165271

Strand: Reverse

Name: ribB [H]

Synonym: Sama_0143

Alternate gene names: 119773285

Gene position: 165271-164603 (Counterclockwise)

Preceding gene: 119773299

Following gene: 119773284

Centisome position: 3.84

GC content: 58.89

Gene sequence:

>669_bases
ATGGATCAGATTCAAACATCCCCTTCACTGCTGGCGCAGTTTGGCAATCCGCTTACCCGGGTCGATGCGGCCCTCGATGC
ACTGCGGCGCGGCCATGGCGTACTTGTGGTCGACGATGAAGACCGTGAAAACGAAGGCGACCTGATTTTTGCCGCCGAGT
CATTAACCAATGCGCAGATGGCCATGCTTATCCGTGAGTGTTCAGGCATCGTTTGCCTGTGCCTGACCGATGAGCGGGTG
CGCCAGCTTGAGTTGCCACCCATGGTGGCGCAAAACAACAGCCAATACGGTACTGCATTTACCGTGAGTATCGAAGCCAA
ACAAGGCGTCACCACAGGCGTGTCTGCCGCTGACCGGGTCACCACCATCAGGGCAGCCATTGCCGATGGTGCCAAACCCT
GTGATCTGGCCCGTCCGGGTCATGTTTATCCGCTGCGGGCACACCCCGCAGGCGTACTTGGACGCCGTGGTCATACCGAA
GGCACTGTAGACCTGATGCGTCTGGCGGGGCTGAAGCCCTTTGGTGTGCTGTGCGAGCTGACCAACCCAGATGGCACCAT
GGCACGCCTGCCTGAAATCATCGCCTTCGGCCAGGCTCACCAGATGCCGGTGCTCAGCATTGAAGATCTGGTGCAATACC
GTGAGGCACTGATGAGCCAAAGCGCCTGA

Upstream 100 bases:

>100_bases
CGGTCAGTACCGGCTTTCGCACCTTAACACCTTGCCGTGTGGCACAGGTGGATCCTGCTATGCCCTGATCCAATAACCCT
ATGTGATTTAAGGAACTATT

Downstream 100 bases:

>100_bases
CGCTCATTGGGCCATCAAGTCCCCGACAGCTTGGGCACTTAATGCAAAAGGCGACCAGGGGTCGCCTTTTGTTTTGAAAG
ACTAAGGTGGCATACCTATG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MDQIQTSPSLLAQFGNPLTRVDAALDALRRGHGVLVVDDEDRENEGDLIFAAESLTNAQMAMLIRECSGIVCLCLTDERV
RQLELPPMVAQNNSQYGTAFTVSIEAKQGVTTGVSAADRVTTIRAAIADGAKPCDLARPGHVYPLRAHPAGVLGRRGHTE
GTVDLMRLAGLKPFGVLCELTNPDGTMARLPEIIAFGQAHQMPVLSIEDLVQYREALMSQSA

Sequences:

>Translated_222_residues
MDQIQTSPSLLAQFGNPLTRVDAALDALRRGHGVLVVDDEDRENEGDLIFAAESLTNAQMAMLIRECSGIVCLCLTDERV
RQLELPPMVAQNNSQYGTAFTVSIEAKQGVTTGVSAADRVTTIRAAIADGAKPCDLARPGHVYPLRAHPAGVLGRRGHTE
GTVDLMRLAGLKPFGVLCELTNPDGTMARLPEIIAFGQAHQMPVLSIEDLVQYREALMSQSA
>Mature_222_residues
MDQIQTSPSLLAQFGNPLTRVDAALDALRRGHGVLVVDDEDRENEGDLIFAAESLTNAQMAMLIRECSGIVCLCLTDERV
RQLELPPMVAQNNSQYGTAFTVSIEAKQGVTTGVSAADRVTTIRAAIADGAKPCDLARPGHVYPLRAHPAGVLGRRGHTE
GTVDLMRLAGLKPFGVLCELTNPDGTMARLPEIIAFGQAHQMPVLSIEDLVQYREALMSQSA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=208, Percent_Identity=67.7884615384615, Blast_Score=295, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=45.0980392156863, Blast_Score=180, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23863; Mature: 23863

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQIQTSPSLLAQFGNPLTRVDAALDALRRGHGVLVVDDEDRENEGDLIFAAESLTNAQM
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECHHCHHHH
AMLIRECSGIVCLCLTDERVRQLELPPMVAQNNSQYGTAFTVSIEAKQGVTTGVSAADRV
HHHHHHCCCEEEEEECHHHHHHCCCCCCEECCCCCCCEEEEEEEECCCCCCCCCCHHHHH
TTIRAAIADGAKPCDLARPGHVYPLRAHPAGVLGRRGHTEGTVDLMRLAGLKPFGVLCEL
HHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEE
TNPDGTMARLPEIIAFGQAHQMPVLSIEDLVQYREALMSQSA
ECCCCHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDQIQTSPSLLAQFGNPLTRVDAALDALRRGHGVLVVDDEDRENEGDLIFAAESLTNAQM
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECHHCHHHH
AMLIRECSGIVCLCLTDERVRQLELPPMVAQNNSQYGTAFTVSIEAKQGVTTGVSAADRV
HHHHHHCCCEEEEEECHHHHHHCCCCCCEECCCCCCCEEEEEEEECCCCCCCCCCHHHHH
TTIRAAIADGAKPCDLARPGHVYPLRAHPAGVLGRRGHTEGTVDLMRLAGLKPFGVLCEL
HHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEE
TNPDGTMARLPEIIAFGQAHQMPVLSIEDLVQYREALMSQSA
ECCCCHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA