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The map label for this gene is cysW [H]

Identifier: 119773265

GI number: 119773265

Start: 136654

End: 137361

Strand: Reverse

Name: cysW [H]

Synonym: Sama_0123

Alternate gene names: 119773265

Gene position: 137361-136654 (Counterclockwise)

Preceding gene: 119773266

Following gene: 119773264

Centisome position: 3.19

GC content: 56.21

Gene sequence:

>708_bases
ATGAGTCAAAGTTGGTTTGAACTGATACAGCAGGCCCTGGGCCTGCTGTTTTCCCTCGACAAAGATCTCTGGTCGATTAT
CTGGGTGTCTTTTGGCGTTTCCCTCGCGGCCCTGCTGATCACCCTCATCCCCTCGATGCTGCTGGGCTTTGTGCTCGCCT
TCAAGCAGTTTCCCGGCCGTCACTTTGTCCTGAATCTGGTGCAAACCCTGCAATCCATACCCACTGTGGTGATTGGCTTG
CTGGTGTATTTACTGCTGACCCGCATGGGGCCGTTGGGCGACCTGCGCTGGCTCTTTACCCAGCAGGGGATGATCCTCGG
GCAAATGCTGATTTGTGCGCCCGTACTCATTGCTATGAGCCAGGCGGCCTTTACCAGCGCCGATAAGCGCGCATGGGAAA
CTGCCCTTACCCTTGGCGCCTCGCTGCCCAGGGCCATACTCATGGTCAGTGGTGAACTGCGCGGCCCCTTGCTGCTGGCC
GTTATCGCCGCATTTTCCCGCATTGTGACCGAGGTGGGCTGCTCCATGATGGTTGGCGGCAACATCGAGTATGTTACCCG
TAATATTCCCACCGCCATTGCGCTGGAAACCAGTAAGGGCGACTTTGCTCAGGCCATAGCACTCGGGTTGGTGTTGTTGT
TTTTGGCCATTATTATGAACTTTGCCCTGGGGAACCTCAGGGGCAAGAATCAGGTAAGGAGTCACTGA

Upstream 100 bases:

>100_bases
CCAAAGCCCTGAGTGACTGGCTGATCAGCGCCGAAGGACAGAAGATGATCAATGACTTTAAAGTTCAGGGAGAGCAGCTC
TTCAAGGCCACTTATCGTCA

Downstream 100 bases:

>100_bases
TGGCGAGGATCCTTGCCCATGATTTGGGCATTCGCTTCGGCCAACGACAATTATTTGAGTCGGCTAATCTGACCTTTGCC
GAAGGGGATTGCATTTACCT

Product: ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSQSWFELIQQALGLLFSLDKDLWSIIWVSFGVSLAALLITLIPSMLLGFVLAFKQFPGRHFVLNLVQTLQSIPTVVIGL
LVYLLLTRMGPLGDLRWLFTQQGMILGQMLICAPVLIAMSQAAFTSADKRAWETALTLGASLPRAILMVSGELRGPLLLA
VIAAFSRIVTEVGCSMMVGGNIEYVTRNIPTAIALETSKGDFAQAIALGLVLLFLAIIMNFALGNLRGKNQVRSH

Sequences:

>Translated_235_residues
MSQSWFELIQQALGLLFSLDKDLWSIIWVSFGVSLAALLITLIPSMLLGFVLAFKQFPGRHFVLNLVQTLQSIPTVVIGL
LVYLLLTRMGPLGDLRWLFTQQGMILGQMLICAPVLIAMSQAAFTSADKRAWETALTLGASLPRAILMVSGELRGPLLLA
VIAAFSRIVTEVGCSMMVGGNIEYVTRNIPTAIALETSKGDFAQAIALGLVLLFLAIIMNFALGNLRGKNQVRSH
>Mature_234_residues
SQSWFELIQQALGLLFSLDKDLWSIIWVSFGVSLAALLITLIPSMLLGFVLAFKQFPGRHFVLNLVQTLQSIPTVVIGLL
VYLLLTRMGPLGDLRWLFTQQGMILGQMLICAPVLIAMSQAAFTSADKRAWETALTLGASLPRAILMVSGELRGPLLLAV
IAAFSRIVTEVGCSMMVGGNIEYVTRNIPTAIALETSKGDFAQAIALGLVLLFLAIIMNFALGNLRGKNQVRSH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4662

COG function: function code H; ABC-type tungstate transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=230, Percent_Identity=27.8260869565217, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25560; Mature: 25429

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSWFELIQQALGLLFSLDKDLWSIIWVSFGVSLAALLITLIPSMLLGFVLAFKQFPGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HFVLNLVQTLQSIPTVVIGLLVYLLLTRMGPLGDLRWLFTQQGMILGQMLICAPVLIAMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QAAFTSADKRAWETALTLGASLPRAILMVSGELRGPLLLAVIAAFSRIVTEVGCSMMVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHEECC
NIEYVTRNIPTAIALETSKGDFAQAIALGLVLLFLAIIMNFALGNLRGKNQVRSH
CHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure 
SQSWFELIQQALGLLFSLDKDLWSIIWVSFGVSLAALLITLIPSMLLGFVLAFKQFPGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HFVLNLVQTLQSIPTVVIGLLVYLLLTRMGPLGDLRWLFTQQGMILGQMLICAPVLIAMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QAAFTSADKRAWETALTLGASLPRAILMVSGELRGPLLLAVIAAFSRIVTEVGCSMMVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHEECC
NIEYVTRNIPTAIALETSKGDFAQAIALGLVLLFLAIIMNFALGNLRGKNQVRSH
CHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]