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The map label for this gene is hutI

Identifier: 119773222

GI number: 119773222

Start: 87909

End: 89147

Strand: Reverse

Name: hutI

Synonym: Sama_0080

Alternate gene names: 119773222

Gene position: 89147-87909 (Counterclockwise)

Preceding gene: 119773225

Following gene: 119773221

Centisome position: 2.07

GC content: 59.81

Gene sequence:

>1239_bases
ATGTCTTGGGATCAGGTTTGGATTGATATCAATATTGCCACCATGGACCCATCCATGAACGAGGCTTATGGCGCCATTAC
CGATGCGGCGCTGGCGGTAAAAGACGGCAAAATAGCCTGGCTTGGCAAGCGCAGCGACCTGCCCGAATTCGATGTGCTGG
CCACCCCTGTACACCGCGGCCATGGCGGCTGGCTGACCCCCGGCCTGATTGATGCCCACACTCACCTGGTATTTGCCGGT
AATCGCGCCAACGAATTTGAGCTGCGTCTGCAGGGCGCAAGCTACGAAGAAATCGCCCGCGCCGGCGGCGGCATTGTCAG
CACAGTAAAAGCCTGCCGCGACGCCGACGAAGCCGAGCTGTTTGACCTCGCCCGTCGCCGCCTGAATGCGTTGGCAAAGG
AAGGGGTTACCACGGTGGAAATCAAATCAGGCTACGGCCTGGATTTGGATACCGAGCTTAAGCTACTGCGGGTTGCCCGC
GAGCTTGGCCAGCACCACCACGTGGATGTAGTCACCACCTTCCTCGGTGCCCATGCCGTGCCCCCTGAGTTCAAAACCCT
GGGCGAAGCCGGAACCGATGCCTATGTGGATCTGGTGGTCAACGAAATGCTGCCCGCCGTGGTGGCCGAGAACCTTGCCG
ATGCCGCCGACGTATTCTGCGAAAACATCGCCTTTAACCTAGAGCAAACCGAGCGGGTTCTGAGCGCCGCCAAAACTTTG
GGGCTGGATATCAAGCTGCACGCCGAGCAGCTCAGCAACCTCGGAGGCAGTGAACTGGCCGCGCGTCTTGGCGCCAAGTC
GGTTGACCATATCGAATACCTCGACGAAGCCGGCGTAAAGGCCATTGCCCAAAGCGGCACCTGCGCCGTGCTGTTGCCGG
GCGCCTTCTACTTCCTGCGGGAAACCAAGCTGCCTCCCATCGACCTTTTGCGTCAGTATCAGGTGCCCATGGTGCTTGCC
AGCGATTTTAACCCCGGTTCATCACCTATCTGCTCGACCCTGCTGATGCTGAACATGGGCTGCACCCTGTTCCGTCTGAC
GCCGGAAGAGGCCCTTGCCGGCGTAACCCGTAACGCCGCCCGCGCCCTTGGCCGTGACCAGCGCGTGGGCGTGTTACGTG
AAGGTATGGAGGCCGACTTCTGCCTGTGGCGTATCTCCACCCCGGCGGAGCTGGCATACTCCTATGGCGTAAATCCACTG
GTGGATGTGGTGAAAGGTGGCAGGCTAATTCATCAATAA

Upstream 100 bases:

>100_bases
AGCCGTAACAATAGAAACAATAGATTAGTCAGTTGCCGCGACCTATTTTTATAACGACGGTACACAAAAAGCCTACATAA
CAGCCACAGCAGGAGTCAGC

Downstream 100 bases:

>100_bases
GGGCCCGGAATTGTTTCGGGAGCCAAGGCACGTTTTAATCTTGCGCTCCCCTATTAACTTCAACTTAGTTGGTACTGTCA
CCACAACCATTTCAATCATT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSWDQVWIDINIATMDPSMNEAYGAITDAALAVKDGKIAWLGKRSDLPEFDVLATPVHRGHGGWLTPGLIDAHTHLVFAG
NRANEFELRLQGASYEEIARAGGGIVSTVKACRDADEAELFDLARRRLNALAKEGVTTVEIKSGYGLDLDTELKLLRVAR
ELGQHHHVDVVTTFLGAHAVPPEFKTLGEAGTDAYVDLVVNEMLPAVVAENLADAADVFCENIAFNLEQTERVLSAAKTL
GLDIKLHAEQLSNLGGSELAARLGAKSVDHIEYLDEAGVKAIAQSGTCAVLLPGAFYFLRETKLPPIDLLRQYQVPMVLA
SDFNPGSSPICSTLLMLNMGCTLFRLTPEEALAGVTRNAARALGRDQRVGVLREGMEADFCLWRISTPAELAYSYGVNPL
VDVVKGGRLIHQ

Sequences:

>Translated_412_residues
MSWDQVWIDINIATMDPSMNEAYGAITDAALAVKDGKIAWLGKRSDLPEFDVLATPVHRGHGGWLTPGLIDAHTHLVFAG
NRANEFELRLQGASYEEIARAGGGIVSTVKACRDADEAELFDLARRRLNALAKEGVTTVEIKSGYGLDLDTELKLLRVAR
ELGQHHHVDVVTTFLGAHAVPPEFKTLGEAGTDAYVDLVVNEMLPAVVAENLADAADVFCENIAFNLEQTERVLSAAKTL
GLDIKLHAEQLSNLGGSELAARLGAKSVDHIEYLDEAGVKAIAQSGTCAVLLPGAFYFLRETKLPPIDLLRQYQVPMVLA
SDFNPGSSPICSTLLMLNMGCTLFRLTPEEALAGVTRNAARALGRDQRVGVLREGMEADFCLWRISTPAELAYSYGVNPL
VDVVKGGRLIHQ
>Mature_411_residues
SWDQVWIDINIATMDPSMNEAYGAITDAALAVKDGKIAWLGKRSDLPEFDVLATPVHRGHGGWLTPGLIDAHTHLVFAGN
RANEFELRLQGASYEEIARAGGGIVSTVKACRDADEAELFDLARRRLNALAKEGVTTVEIKSGYGLDLDTELKLLRVARE
LGQHHHVDVVTTFLGAHAVPPEFKTLGEAGTDAYVDLVVNEMLPAVVAENLADAADVFCENIAFNLEQTERVLSAAKTLG
LDIKLHAEQLSNLGGSELAARLGAKSVDHIEYLDEAGVKAIAQSGTCAVLLPGAFYFLRETKLPPIDLLRQYQVPMVLAS
DFNPGSSPICSTLLMLNMGCTLFRLTPEEALAGVTRNAARALGRDQRVGVLREGMEADFCLWRISTPAELAYSYGVNPLV
DVVKGGRLIHQ

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=358, Percent_Identity=39.1061452513966, Blast_Score=218, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI17555004, Length=377, Percent_Identity=33.42175066313, Blast_Score=214, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_SHEAM (A1S1N6)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_925962.1
- ProteinModelPortal:   A1S1N6
- SMR:   A1S1N6
- STRING:   A1S1N6
- GeneID:   4602337
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0080
- NMPDR:   fig|326297.7.peg.74
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR013108
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF07969 Amidohydro_3; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 44583; Mature: 44452

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: BINDING 82-82 BINDING 95-95 BINDING 145-145 BINDING 178-178 BINDING 250-250

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWDQVWIDINIATMDPSMNEAYGAITDAALAVKDGKIAWLGKRSDLPEFDVLATPVHRG
CCCCEEEEEEEEEEECCCCHHHHHHHHHHEEEEECCCEEEEECCCCCCCCCEEECCCCCC
HGGWLTPGLIDAHTHLVFAGNRANEFELRLQGASYEEIARAGGGIVSTVKACRDADEAEL
CCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHCCCCHHHH
FDLARRRLNALAKEGVTTVEIKSGYGLDLDTELKLLRVARELGQHHHVDVVTTFLGAHAV
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
PPEFKTLGEAGTDAYVDLVVNEMLPAVVAENLADAADVFCENIAFNLEQTERVLSAAKTL
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GLDIKLHAEQLSNLGGSELAARLGAKSVDHIEYLDEAGVKAIAQSGTCAVLLPGAFYFLR
CCEEEEEHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCEEHHH
ETKLPPIDLLRQYQVPMVLASDFNPGSSPICSTLLMLNMGCTLFRLTPEEALAGVTRNAA
HCCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHH
RALGRDQRVGVLREGMEADFCLWRISTPAELAYSYGVNPLVDVVKGGRLIHQ
HHCCCCCCHHHHHCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SWDQVWIDINIATMDPSMNEAYGAITDAALAVKDGKIAWLGKRSDLPEFDVLATPVHRG
CCCEEEEEEEEEEECCCCHHHHHHHHHHEEEEECCCEEEEECCCCCCCCCEEECCCCCC
HGGWLTPGLIDAHTHLVFAGNRANEFELRLQGASYEEIARAGGGIVSTVKACRDADEAEL
CCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHCCCCHHHH
FDLARRRLNALAKEGVTTVEIKSGYGLDLDTELKLLRVARELGQHHHVDVVTTFLGAHAV
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
PPEFKTLGEAGTDAYVDLVVNEMLPAVVAENLADAADVFCENIAFNLEQTERVLSAAKTL
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GLDIKLHAEQLSNLGGSELAARLGAKSVDHIEYLDEAGVKAIAQSGTCAVLLPGAFYFLR
CCEEEEEHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCEEHHH
ETKLPPIDLLRQYQVPMVLASDFNPGSSPICSTLLMLNMGCTLFRLTPEEALAGVTRNAA
HCCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHH
RALGRDQRVGVLREGMEADFCLWRISTPAELAYSYGVNPLVDVVKGGRLIHQ
HHCCCCCCHHHHHCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA