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The map label for this gene is trkH [H]

Identifier: 119773181

GI number: 119773181

Start: 41933

End: 43375

Strand: Reverse

Name: trkH [H]

Synonym: Sama_0039

Alternate gene names: 119773181

Gene position: 43375-41933 (Counterclockwise)

Preceding gene: 119773182

Following gene: 119773179

Centisome position: 1.01

GC content: 54.4

Gene sequence:

>1443_bases
ATGCTGAACCTAAGACCGCTGCTCTTTATACTCGGCACTTTTTTGTCGATGTTGGCGGGCTTTATGCTTATCCCTCTGCT
GTTTGCCTTGTTGCATGGGGATGAGACTTCCGGCGCCTTTATGATTTCTTCTCTGGCCACAGGGGCAGCCGCCAGTTTCT
GTATCAGCAGCGGCCAGCAGAAAAATATCAAACTCAATATTCGCGACATGTTTTTACTGACCAGTATCACCTGGTTGGTG
GTCAGCCTGTTCGCGGCCATGCCTTTTACCCTGTATCACGGTATTAACTATACCGATGCCTTCTTCGAAACCATGTCGGG
TATCACCACCACGGGTTCGACCGTGCTGTCGGGCTTGGATAGCATGGACCGCAGCATCCTGATTTGGCGCTCTTTGCTGC
AATGGCTGGGGGGAATTGGCTTTATCGTGATGGCGGTGGCCGTACTGCCTTTTTTGAACGTAGGTGGCATGCGGCTGTTT
CGCACTGAGTCATCGGACTGGAGCGACAAGTCCACACCTCGCACCCAGGACATGGCCAAGAATTTGTTTCTGGTTTACAT
CCTGCTGACCATACTTTGCGGCCTCGGCTATCACCTGGCGGGCATGGATTGGTTTGAGGCCATTAACCACGCCATGACCA
CCCTCTCCACAGGCGGCTATTCAACATCAGACGAGTCCATGGCACATTTCAGCCCGGCTGCACACTGGGTAGGCACCAGC
TTTATGCTGGCAGGCGGTTTGCCTTTACTTATCTTTGTGCAGATGCTGCGTGGCCGCAGCCTGACGGTATGGAATGATGC
CCAGGTGAAAGGCTTTTTGCTGTTTGTGGCTCTGGTCAGTGTTGCGCTCAGTTTCTGGCTGGCCGATGTGAAAGATCTCG
CCTTTATGGATGCCCTGCGTCTGACCAGCTTTAACGTAGTCTCTGTGGTTACTACCACCGGCTATGGCCTTACCGATTAT
GGAAGCTGGGGGCCACTGGCCAATGTGGCATTTTTGTTTTTGATGTTTGTGGGCGCCTGCTCTGGTTCTACCTCTGGCGG
GATTAAAATCTTCCGCTTTCAAATCGCCGGCGCCATCATGCGCGAGCAATTAAAGCAGCAAATACATCCTGCGGGGATTT
TCCGCGAGCGTTACAACAACCGCCCCATCAGCGAAGATATTATTCGTTCCCTGGTGACCTTTATCCTGCTGTTTATGGGG
GTGACGGTCGCGTTGGCAGTGTTTTTGGTGGCCGTGGGTGTCGACCCCATGTCGAGTCTCACCGGTGCCATCACGGCGGT
CACCAATGTCGGCCCGGGGCTTGGACCCGTGATAGGCCCGGCGGGTAACTTTGCCAGCCTGCCCGACAGTGCCAAGTGGG
CCCTCTCGTTGGGTATGTTATTGGGGCGGCTGGAGATCCTCACGGTTGCCGTGCTCTTCCACCCCAAGTTCTGGCACTAC
TGA

Upstream 100 bases:

>100_bases
TGATCGAACAGGGCGACCATGTGATCCTCTTCCTGGTAAACAAGAAATTTATCGGCGAGGTCGAACGGTTGTTCCAACCC
AGCGCTTTCTTCTTCTAACC

Downstream 100 bases:

>100_bases
CCCGCTTATTTCAGCATTGCCAGATGGTCGGCATAGGCGTCGACATCCTGCCAGTCTGTGTAGTCTATGACCGCCTTGGG
GTCGGTCGGGCCATTGGTCA

Product: potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MLNLRPLLFILGTFLSMLAGFMLIPLLFALLHGDETSGAFMISSLATGAAASFCISSGQQKNIKLNIRDMFLLTSITWLV
VSLFAAMPFTLYHGINYTDAFFETMSGITTTGSTVLSGLDSMDRSILIWRSLLQWLGGIGFIVMAVAVLPFLNVGGMRLF
RTESSDWSDKSTPRTQDMAKNLFLVYILLTILCGLGYHLAGMDWFEAINHAMTTLSTGGYSTSDESMAHFSPAAHWVGTS
FMLAGGLPLLIFVQMLRGRSLTVWNDAQVKGFLLFVALVSVALSFWLADVKDLAFMDALRLTSFNVVSVVTTTGYGLTDY
GSWGPLANVAFLFLMFVGACSGSTSGGIKIFRFQIAGAIMREQLKQQIHPAGIFRERYNNRPISEDIIRSLVTFILLFMG
VTVALAVFLVAVGVDPMSSLTGAITAVTNVGPGLGPVIGPAGNFASLPDSAKWALSLGMLLGRLEILTVAVLFHPKFWHY

Sequences:

>Translated_480_residues
MLNLRPLLFILGTFLSMLAGFMLIPLLFALLHGDETSGAFMISSLATGAAASFCISSGQQKNIKLNIRDMFLLTSITWLV
VSLFAAMPFTLYHGINYTDAFFETMSGITTTGSTVLSGLDSMDRSILIWRSLLQWLGGIGFIVMAVAVLPFLNVGGMRLF
RTESSDWSDKSTPRTQDMAKNLFLVYILLTILCGLGYHLAGMDWFEAINHAMTTLSTGGYSTSDESMAHFSPAAHWVGTS
FMLAGGLPLLIFVQMLRGRSLTVWNDAQVKGFLLFVALVSVALSFWLADVKDLAFMDALRLTSFNVVSVVTTTGYGLTDY
GSWGPLANVAFLFLMFVGACSGSTSGGIKIFRFQIAGAIMREQLKQQIHPAGIFRERYNNRPISEDIIRSLVTFILLFMG
VTVALAVFLVAVGVDPMSSLTGAITAVTNVGPGLGPVIGPAGNFASLPDSAKWALSLGMLLGRLEILTVAVLFHPKFWHY
>Mature_480_residues
MLNLRPLLFILGTFLSMLAGFMLIPLLFALLHGDETSGAFMISSLATGAAASFCISSGQQKNIKLNIRDMFLLTSITWLV
VSLFAAMPFTLYHGINYTDAFFETMSGITTTGSTVLSGLDSMDRSILIWRSLLQWLGGIGFIVMAVAVLPFLNVGGMRLF
RTESSDWSDKSTPRTQDMAKNLFLVYILLTILCGLGYHLAGMDWFEAINHAMTTLSTGGYSTSDESMAHFSPAAHWVGTS
FMLAGGLPLLIFVQMLRGRSLTVWNDAQVKGFLLFVALVSVALSFWLADVKDLAFMDALRLTSFNVVSVVTTTGYGLTDY
GSWGPLANVAFLFLMFVGACSGSTSGGIKIFRFQIAGAIMREQLKQQIHPAGIFRERYNNRPISEDIIRSLVTFILLFMG
VTVALAVFLVAVGVDPMSSLTGAITAVTNVGPGLGPVIGPAGNFASLPDSAKWALSLGMLLGRLEILTVAVLFHPKFWHY

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=486, Percent_Identity=37.037037037037, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1787626, Length=474, Percent_Identity=33.9662447257384, Blast_Score=234, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52114; Mature: 52114

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLRPLLFILGTFLSMLAGFMLIPLLFALLHGDETSGAFMISSLATGAAASFCISSGQQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
KNIKLNIRDMFLLTSITWLVVSLFAAMPFTLYHGINYTDAFFETMSGITTTGSTVLSGLD
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
SMDRSILIWRSLLQWLGGIGFIVMAVAVLPFLNVGGMRLFRTESSDWSDKSTPRTQDMAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHH
NLFLVYILLTILCGLGYHLAGMDWFEAINHAMTTLSTGGYSTSDESMAHFSPAAHWVGTS
HHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHH
FMLAGGLPLLIFVQMLRGRSLTVWNDAQVKGFLLFVALVSVALSFWLADVKDLAFMDALR
HHHHCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTSFNVVSVVTTTGYGLTDYGSWGPLANVAFLFLMFVGACSGSTSGGIKIFRFQIAGAIM
HCCCHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHH
REQLKQQIHPAGIFRERYNNRPISEDIIRSLVTFILLFMGVTVALAVFLVAVGVDPMSSL
HHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TGAITAVTNVGPGLGPVIGPAGNFASLPDSAKWALSLGMLLGRLEILTVAVLFHPKFWHY
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MLNLRPLLFILGTFLSMLAGFMLIPLLFALLHGDETSGAFMISSLATGAAASFCISSGQQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
KNIKLNIRDMFLLTSITWLVVSLFAAMPFTLYHGINYTDAFFETMSGITTTGSTVLSGLD
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
SMDRSILIWRSLLQWLGGIGFIVMAVAVLPFLNVGGMRLFRTESSDWSDKSTPRTQDMAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHH
NLFLVYILLTILCGLGYHLAGMDWFEAINHAMTTLSTGGYSTSDESMAHFSPAAHWVGTS
HHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHH
FMLAGGLPLLIFVQMLRGRSLTVWNDAQVKGFLLFVALVSVALSFWLADVKDLAFMDALR
HHHHCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTSFNVVSVVTTTGYGLTDYGSWGPLANVAFLFLMFVGACSGSTSGGIKIFRFQIAGAIM
HCCCHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHH
REQLKQQIHPAGIFRERYNNRPISEDIIRSLVTFILLFMGVTVALAVFLVAVGVDPMSSL
HHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TGAITAVTNVGPGLGPVIGPAGNFASLPDSAKWALSLGMLLGRLEILTVAVLFHPKFWHY
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]