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The map label for this gene is pcp [H]

Identifier: 119773160

GI number: 119773160

Start: 17393

End: 18046

Strand: Reverse

Name: pcp [H]

Synonym: Sama_0018

Alternate gene names: 119773160

Gene position: 18046-17393 (Counterclockwise)

Preceding gene: 119773161

Following gene: 119773159

Centisome position: 0.42

GC content: 59.63

Gene sequence:

>654_bases
ATGAAACCCGTGCCACTGATTTTGCTCACCGGATTTGAACCCTTCGGCGGCGAGGTAATTAACCCATCCTGGGAGGCGGT
AAAAAACCTCGATGGCGAGCTTATCTGCCGCCACAGGATCAAAGCCATCAAGCTGCCCTGCGTGTTCCACGATTCGCTCA
CTCAGCTAACCGAGGCCATCGATTATCACCAGCCGGCCCTGGTGCTCTGTGTTGGCCAGGCAAGCGGACGCAGCGAACTG
ACCCTTGAGCGCATTGGCATCAATATCGATGATGCGCGTATTGCCGATAACCGTGGCCAGCAACCCATTGATGAGCCCGT
GATAGCCGGAGGCCCGGCGGCCTACTTCGCCACCCTGCCCATCAAGGCCATGGTGCGCGACCTGAAGGAAGCGGGGATCC
CGGCAGCCGTCTCCAACACCGCGGGAACCTTTGTTTGCAACCATGTGCTCTATGGCATGCTGCATCAGCTGAGCCAGACT
CCCGAATGCCGTGGCGGCTTTTTGCATATCCCCCTGGCACCGGAACAGGCCTCACGCCAACCGGGGACCCCATCTATGGC
GTTGGAAACCGTTATCCACGGTCTGCGACTGATGCTGGCCACCGCTGTCACCACAGCCACCGATATCCACGAGAGCGCCG
GAGTCACCCACTGA

Upstream 100 bases:

>100_bases
AGTATCAGGTCATTAAGGTACAAATACCCACGGCGCTGGCGTTGCTGACAACCAACATTTTGCTGATGTATTTCATCGTT
TTTGACTGAGCGAGCCCATT

Downstream 100 bases:

>100_bases
TGGCTTTCGACGATACCTTCCGCTTGAGCAGCCACGCGGTGATCACCAACGACAAAAATAACGTGCTGCTACTTAAAGCT
GACTATGGCAATAAGCATTG

Product: pyroglutamyl-peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKPVPLILLTGFEPFGGEVINPSWEAVKNLDGELICRHRIKAIKLPCVFHDSLTQLTEAIDYHQPALVLCVGQASGRSEL
TLERIGINIDDARIADNRGQQPIDEPVIAGGPAAYFATLPIKAMVRDLKEAGIPAAVSNTAGTFVCNHVLYGMLHQLSQT
PECRGGFLHIPLAPEQASRQPGTPSMALETVIHGLRLMLATAVTTATDIHESAGVTH

Sequences:

>Translated_217_residues
MKPVPLILLTGFEPFGGEVINPSWEAVKNLDGELICRHRIKAIKLPCVFHDSLTQLTEAIDYHQPALVLCVGQASGRSEL
TLERIGINIDDARIADNRGQQPIDEPVIAGGPAAYFATLPIKAMVRDLKEAGIPAAVSNTAGTFVCNHVLYGMLHQLSQT
PECRGGFLHIPLAPEQASRQPGTPSMALETVIHGLRLMLATAVTTATDIHESAGVTH
>Mature_217_residues
MKPVPLILLTGFEPFGGEVINPSWEAVKNLDGELICRHRIKAIKLPCVFHDSLTQLTEAIDYHQPALVLCVGQASGRSEL
TLERIGINIDDARIADNRGQQPIDEPVIAGGPAAYFATLPIKAMVRDLKEAGIPAAVSNTAGTFVCNHVLYGMLHQLSQT
PECRGGFLHIPLAPEQASRQPGTPSMALETVIHGLRLMLATAVTTATDIHESAGVTH

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 23296; Mature: 23296

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVPLILLTGFEPFGGEVINPSWEAVKNLDGELICRHRIKAIKLPCVFHDSLTQLTEAI
CCCCCEEEEECCCCCCCCEECCCHHHHHCCCHHHHHHHHHHHEECCEEEHHHHHHHHHHH
DYHQPALVLCVGQASGRSELTLERIGINIDDARIADNRGQQPIDEPVIAGGPAAYFATLP
HCCCCEEEEEECCCCCCCCEEHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHCC
IKAMVRDLKEAGIPAAVSNTAGTFVCNHVLYGMLHQLSQTPECRGGFLHIPLAPEQASRQ
HHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHCCC
PGTPSMALETVIHGLRLMLATAVTTATDIHESAGVTH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKPVPLILLTGFEPFGGEVINPSWEAVKNLDGELICRHRIKAIKLPCVFHDSLTQLTEAI
CCCCCEEEEECCCCCCCCEECCCHHHHHCCCHHHHHHHHHHHEECCEEEHHHHHHHHHHH
DYHQPALVLCVGQASGRSELTLERIGINIDDARIADNRGQQPIDEPVIAGGPAAYFATLP
HCCCCEEEEEECCCCCCCCEEHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHCC
IKAMVRDLKEAGIPAAVSNTAGTFVCNHVLYGMLHQLSQTPECRGGFLHIPLAPEQASRQ
HHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHCCC
PGTPSMALETVIHGLRLMLATAVTTATDIHESAGVTH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA