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The map label for this gene is oxaA

Identifier: 119773151

GI number: 119773151

Start: 7951

End: 9576

Strand: Reverse

Name: oxaA

Synonym: Sama_0009

Alternate gene names: 119773151

Gene position: 9576-7951 (Counterclockwise)

Preceding gene: 119773152

Following gene: 119773150

Centisome position: 0.22

GC content: 54.18

Gene sequence:

>1626_bases
ATGGAATCACAACGCAATCTATTGCTCATCGGCCTGCTGTTTGTCAGCTTTTTGCTTTGGCAACAGTGGGAATCCGACAA
GGCGCCCAAGCCAGCCACAGAAGTAACTGCGGCGGCCCAAATCCACGACCAGGCTATCAACAGTGACGTTCCAACAGCCG
ATGCCGGTGTACCTGCCACAGTGGCAGCAACCCAAAACCTGATCCTCGTTACCACAGATCAACTGGAAATCCAGATTAAT
CCTGTGGGCGGTGACATAGTGCATGCCGCCCTGCTGACCCATAAGCTGGAACAAAACGAAGAAGCACCTTTTGTTCTGCT
GGAGCAGAAAAACAACTTCTCCTACATCGCCCAGAGTGGTCTGATTGGTCGTGATGGTATCGACAGCGCCGCCAGTGGCC
GCGCCAAGTTCGCTGCCGCCGCCGACGCCTACACCCTGGCTGACGGCCAGGACACCCTGGAAGTGCCACTGACTCTGACC
ACAGATGCCGGTGTAACCTTCACCAAGGTGTTCGTGTTCAAGCGTGGTCAGTTTGATGTGGGCGTGGATTACCGCGTTGC
CAACAACTCTGCAGCCCCTGTACAGGTGCAGATGTATGGCCAAATCAAGCAAACCATCACTGCCAGCGAAAGCAGCATGA
TGATGCCCACCTACCGTGGCGCCGCCTTCTCAACCGCCGATGTGCGTTATGAGAAGTACAGCTTCGATGACATGGGTAAA
AAAGACCTCGAAGAGCCGACTCTGGGTGGTTGGGTTGCCATGCTGCAACACTACTTCGTGTCTGCCTGGGTTCCCGCTGC
AGCTGACAAGAACACCCTGTTCACCTCTGTCAGTGCCGGTGGTCTGGCCAATATCGGCTTCAAGGGCTCGGTTCATGACG
TAGCACCCGGTGCCACAGAAACCATTTCCGCCACCTTCTACGTTGGTCCAAAAGATCAGGCTGCTCTGTCTGCTTTGTCT
GACACCCTGAACCTGGTAGTGGATTACGGTTTCCTCTGGTGGCTGGCTGTACCAATCCACTGGATCCTGATGTTCTTCCA
AAGCCTGGTGCACAACTGGGGTGTGGCCATCATTCTGGTGACCCTGACTGTTCGTGGTCTCTTGTATCCACTGACCAAGG
CACAGTATGTGTCCATGGCCAAGATGCGTAACCTGCAGCCTAAATTGCAGGACCTGAAAGACCGCTTTGGTGATGACCGT
CAGAAGATGGGTCAGGCCATGATGGAGCTGTACAAGAAGGAAAAGGTTAACCCCATGGGCGGCTGTCTGCCCATCCTGCT
GCAGATGCCAATCTTCATCGCCCTGTACTGGGTGCTGCTGGAAAGCGTTGAACTGCGCCACGCGCCATTTATGCTGTGGA
TCCAGGATTTGTCAGTGCAGGACCCTTACTACGTACTGCCGCTGCTGATGGGCGCTTCCATGTGGGCGATGCAAAAGATG
CAGCCAATGGCCCCCAACATGGACCCGATGCAACAAAAAATGCTGCAGTGGATGCCGATGATCTTCACCGTATTCTTCCT
GTGGTTCCCAGCAGGTCTGGTACTCTACTGGCTGGTGGGTAACCTGGTTGCCATCACCCAGCAGAAGATTATTTATGCCT
CACTGGAGAAAAAAGGCTTAAAATAA

Upstream 100 bases:

>100_bases
AGTTGGTTTGCAGCCAAACGCATATTAAAATGTCACCCTTTACATCCGGGCGGCAACGATCCCGTCCCTCCGAAAAAAGA
CAGGTGTAATAAATAAGGCT

Downstream 100 bases:

>100_bases
GCCCATTTTTCAGGCGAGACACTAAAAAGGCGACCTGAGGTCGCCTTTTTGTTTCTATTTGAAGTACACAATTAAGCGGA
AAGACACGTGACGACAGACA

Product: inner membrane protein, 60 kDa

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MESQRNLLLIGLLFVSFLLWQQWESDKAPKPATEVTAAAQIHDQAINSDVPTADAGVPATVAATQNLILVTTDQLEIQIN
PVGGDIVHAALLTHKLEQNEEAPFVLLEQKNNFSYIAQSGLIGRDGIDSAASGRAKFAAAADAYTLADGQDTLEVPLTLT
TDAGVTFTKVFVFKRGQFDVGVDYRVANNSAAPVQVQMYGQIKQTITASESSMMMPTYRGAAFSTADVRYEKYSFDDMGK
KDLEEPTLGGWVAMLQHYFVSAWVPAAADKNTLFTSVSAGGLANIGFKGSVHDVAPGATETISATFYVGPKDQAALSALS
DTLNLVVDYGFLWWLAVPIHWILMFFQSLVHNWGVAIILVTLTVRGLLYPLTKAQYVSMAKMRNLQPKLQDLKDRFGDDR
QKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWIQDLSVQDPYYVLPLLMGASMWAMQKM
QPMAPNMDPMQQKMLQWMPMIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYASLEKKGLK

Sequences:

>Translated_541_residues
MESQRNLLLIGLLFVSFLLWQQWESDKAPKPATEVTAAAQIHDQAINSDVPTADAGVPATVAATQNLILVTTDQLEIQIN
PVGGDIVHAALLTHKLEQNEEAPFVLLEQKNNFSYIAQSGLIGRDGIDSAASGRAKFAAAADAYTLADGQDTLEVPLTLT
TDAGVTFTKVFVFKRGQFDVGVDYRVANNSAAPVQVQMYGQIKQTITASESSMMMPTYRGAAFSTADVRYEKYSFDDMGK
KDLEEPTLGGWVAMLQHYFVSAWVPAAADKNTLFTSVSAGGLANIGFKGSVHDVAPGATETISATFYVGPKDQAALSALS
DTLNLVVDYGFLWWLAVPIHWILMFFQSLVHNWGVAIILVTLTVRGLLYPLTKAQYVSMAKMRNLQPKLQDLKDRFGDDR
QKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWIQDLSVQDPYYVLPLLMGASMWAMQKM
QPMAPNMDPMQQKMLQWMPMIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYASLEKKGLK
>Mature_541_residues
MESQRNLLLIGLLFVSFLLWQQWESDKAPKPATEVTAAAQIHDQAINSDVPTADAGVPATVAATQNLILVTTDQLEIQIN
PVGGDIVHAALLTHKLEQNEEAPFVLLEQKNNFSYIAQSGLIGRDGIDSAASGRAKFAAAADAYTLADGQDTLEVPLTLT
TDAGVTFTKVFVFKRGQFDVGVDYRVANNSAAPVQVQMYGQIKQTITASESSMMMPTYRGAAFSTADVRYEKYSFDDMGK
KDLEEPTLGGWVAMLQHYFVSAWVPAAADKNTLFTSVSAGGLANIGFKGSVHDVAPGATETISATFYVGPKDQAALSALS
DTLNLVVDYGFLWWLAVPIHWILMFFQSLVHNWGVAIILVTLTVRGLLYPLTKAQYVSMAKMRNLQPKLQDLKDRFGDDR
QKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWIQDLSVQDPYYVLPLLMGASMWAMQKM
QPMAPNMDPMQQKMLQWMPMIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYASLEKKGLK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI223718097, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1790140, Length=548, Percent_Identity=51.2773722627737, Blast_Score=552, Evalue=1e-158,
Organism=Drosophila melanogaster, GI24662345, Length=196, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356443, Length=196, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_SHEAM (A1S1G5)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_925891.1
- ProteinModelPortal:   A1S1G5
- SMR:   A1S1G5
- STRING:   A1S1G5
- GeneID:   4602266
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0009
- NMPDR:   fig|326297.7.peg.9
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- PhylomeDB:   A1S1G5
- ProtClustDB:   CLSK905534
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 60037; Mature: 60037

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xda026c4)-; HASH(0x1071d2d8)-; HASH(0x1072f6a4)-; HASH(0x106c43d8)-; HASH(0x101fd038)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQRNLLLIGLLFVSFLLWQQWESDKAPKPATEVTAAAQIHDQAINSDVPTADAGVPAT
CCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VAATQNLILVTTDQLEIQINPVGGDIVHAALLTHKLEQNEEAPFVLLEQKNNFSYIAQSG
EECCCCEEEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCC
LIGRDGIDSAASGRAKFAAAADAYTLADGQDTLEVPLTLTTDAGVTFTKVFVFKRGQFDV
CCCCCCCCCCCCCCCCEEECCCCEEECCCCCCEEEEEEEECCCCCEEEEEEEEECCCCCC
GVDYRVANNSAAPVQVQMYGQIKQTITASESSMMMPTYRGAAFSTADVRYEKYSFDDMGK
CCEEEECCCCCCCEEEEEHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEECCCCCCCC
KDLEEPTLGGWVAMLQHYFVSAWVPAAADKNTLFTSVSAGGLANIGFKGSVHDVAPGATE
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
TISATFYVGPKDQAALSALSDTLNLVVDYGFLWWLAVPIHWILMFFQSLVHNWGVAIILV
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TLTVRGLLYPLTKAQYVSMAKMRNLQPKLQDLKDRFGDDRQKMGQAMMELYKKEKVNPMG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
GCLPILLQMPIFIALYWVLLESVELRHAPFMLWIQDLSVQDPYYVLPLLMGASMWAMQKM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHC
QPMAPNMDPMQQKMLQWMPMIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYASLEKKGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCC
K
H
>Mature Secondary Structure
MESQRNLLLIGLLFVSFLLWQQWESDKAPKPATEVTAAAQIHDQAINSDVPTADAGVPAT
CCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VAATQNLILVTTDQLEIQINPVGGDIVHAALLTHKLEQNEEAPFVLLEQKNNFSYIAQSG
EECCCCEEEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCC
LIGRDGIDSAASGRAKFAAAADAYTLADGQDTLEVPLTLTTDAGVTFTKVFVFKRGQFDV
CCCCCCCCCCCCCCCCEEECCCCEEECCCCCCEEEEEEEECCCCCEEEEEEEEECCCCCC
GVDYRVANNSAAPVQVQMYGQIKQTITASESSMMMPTYRGAAFSTADVRYEKYSFDDMGK
CCEEEECCCCCCCEEEEEHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEECCCCCCCC
KDLEEPTLGGWVAMLQHYFVSAWVPAAADKNTLFTSVSAGGLANIGFKGSVHDVAPGATE
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
TISATFYVGPKDQAALSALSDTLNLVVDYGFLWWLAVPIHWILMFFQSLVHNWGVAIILV
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TLTVRGLLYPLTKAQYVSMAKMRNLQPKLQDLKDRFGDDRQKMGQAMMELYKKEKVNPMG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
GCLPILLQMPIFIALYWVLLESVELRHAPFMLWIQDLSVQDPYYVLPLLMGASMWAMQKM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHC
QPMAPNMDPMQQKMLQWMPMIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYASLEKKGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCC
K
H

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA