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The map label for this gene is yicI [C]

Identifier: 119718847

GI number: 119718847

Start: 4909269

End: 4911503

Strand: Reverse

Name: yicI [C]

Synonym: Noca_4630

Alternate gene names: 119718847

Gene position: 4911503-4909269 (Counterclockwise)

Preceding gene: 119718848

Following gene: 119718846

Centisome position: 98.51

GC content: 72.66

Gene sequence:

>2235_bases
GTGAACCCGGCGGACCGCCCTCCGGTTACCCACCGTCCACACGGCATCGAGCACCCCTATGTGCAGTCCGCCGACCAGCG
GTGCCCGGTGCTGCCCCTGGCCGGCAGCACCTGCCGGATCGGAGTCACCGCCGACCCGGCCGTGGTCGCGGTCCGCTGCG
AGTGGGGGGACCAGGTGCTGGCGATGACCCCACGCACCGTCGATGCCGCCGACGCGGCCGCCCTCGCCGGCGGCGAGGGC
CACCTGGCCGAGGCCCAAGCGAACATGCTCGAGGCCGACGGGGCGTGGACCCTGGAGACCCCCGTGCTGGTGGAGGGCTG
TCGCCTCACCTATCGGTTCGTGGCCGTGACCGCCGACGGCGTGGAGGTCGCGACGCCGGCGTACCACGTCGCACCGGCGG
TCTGGTCGGCGAGCCACCCGGGTCGTCTCCAGGGGGCGGCCGACCGGCTCGTGCCCGGGAGCACGTCGTGGCTCGTCAGC
CCCGACGGCGTCCACCGGGTGCGGTTCGCGCTGGCCCTGCGGCCCGGCGACCACGTCGTCGGGTTCGGGGAGCGCTTCGA
CCGGCTGGACCAGGCCGGCCAGCGCCTCGACGCCGTGGTGTTCGAGCAGTACAAGTCGCAGGGTCGGCACGGGCGGACGT
ACCTCCCGATGCCGTTCGCCCACGTGGTCGGTGCCGACGGCGAATCGTGGGGCTTCCATGTCCGCACCTCGCGGCGCACC
TGGTACGACGTCGGCGCCAGCACCCCGGAAGCGCTGGTGGTGGAGGTCGATCTGGGTACGGGCGGGGACATCGTGGACGT
CGGCATCTACGACGGCACGCCCACCGAGGTGCTGACAGAGTTCCTCGACGAGGTCGGGCGCGCCGAGGAGCTCCCGGAGT
GGGTGCTGCGGCTGTGGGCGTCCGGCAACGAGTGGAACACCCAGCGCCTGGTGATGGATCGGATGGACCGCCACCGCGAG
CTCGACATCCCCGTCGGGGTCGTCGTGATCGAGGCGTGGAGCGACGAGGAGGGCATCACGATCTTCCGGGACGCCCGCTA
CGAGCCGAACCCCGACGGCCGGGCCCATGACGCAGCCGACTTCGCCTACCCGCCGGACGGCGCCTGGCCGGACCCGCACG
GCATGGTCGACGACCTGCACTCCCGGGGCATCAAGGTGGTGCTCTGGCAGATCCCACTCCAGAAGACCGACCCCGAGCTG
ACCGGCCAGGTGCGGATGGACGCCGAGGCGATGGTGCGCGAGGGGCACGCAGTGCTCGAGGCCGACGGATCGGCGTACCA
CAACCGCGGATGGTGGTTCCCGCGGGCGCTGATGCCTGACCTCTCGGTGCAACGCACCCGCGACTGGTGGACGGCCAAGC
GCCGCTACCTGCTCTCCGACCTCGACGTCGACGGCTTCAAGACCGACGGCGGCGAGCACGCCTGGGGGCACGACCTGCGC
TACGCCGACGGACGACGTGGCGACGAGGGCAACAACCTCTTCCCCGTCCACTACGCGCGCGCCTTCGGTGACCTGCTGCG
GTCCGAGGGCAAGGCGCCGGTGACGTTCTCGCGCGCCGGCTTCACGGGGTCGCAGGCGCACGGGGTCTTCTGGGCGGGTG
ACGAGGACTCGACCTGGGAGGCCTTCCGGAGCTCGGTGACCGCCGGTCTGACGGCCGCAGCCTGCGGCATCATCTACTGG
GGCTGGGACCTGGCGGGCTTCTCGGGCCCGGTGCCGGACGCCGAGCTCTACCTGCGGGCCGCCGGCGCCTCGGTGTTCAT
GCCGGTCATGCAGTACCACTCCGAGTTCAACCACCACCGCCCGCCGTTGCGCGACCGGACGCCGTGGAACGTGCAAGAGG
CGAGCGGCGACGAGCGGGTGGTGCCGGTGTTCCGGCACTTCGCGCGGATGCGTGAGCGGCTGGTCCCCTACCTCGCCGAG
CAGGCACGAGCGACGGTCGCCACGGACCGGCCGCTGATGCGGCCGCTGTTCTTCGACCACCCTGCCGACCCGGCGCTCTG
GGCGCACCCCCTCCAGTGGAAGCTGGGCGACGGCATGCTGGTCAACCCGGTCACCGAGCCCGGCGCGACCGCGTGGTCGA
CGTACCTGCCCGCAGGCCAGTGGGTCGACGCGTGGACCGGGACGGCGTACGCCGGCGAGCAGGTCGTCACCGCCGAGGAG
CTGCCCCTCGACCGGGTCCCCGTCTACCTCGCCGCCGACGCCGCGCCCGGCCTCGCCGCGGTGTTCTCCGAATGA

Upstream 100 bases:

>100_bases
TCGACCGCTGGGGGCCGGTAGCGACCCCGCTGCTGTGGTCGCACGGCATGTACCTGATCCTCGCCGACACCCTCGGCCTG
CTGCGCGAGGAGGGCGACCG

Downstream 100 bases:

>100_bases
CCTCATGAACGCCGGCTTCGACGCGCTCCTCGACGCGCTGGTGGCGACCGCGCAGGCGAGCGACGACGTGGTCGGTCTGG
TGGCGTTCGGGTCGACGGCG

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 744; Mature: 744

Protein sequence:

>744_residues
MNPADRPPVTHRPHGIEHPYVQSADQRCPVLPLAGSTCRIGVTADPAVVAVRCEWGDQVLAMTPRTVDAADAAALAGGEG
HLAEAQANMLEADGAWTLETPVLVEGCRLTYRFVAVTADGVEVATPAYHVAPAVWSASHPGRLQGAADRLVPGSTSWLVS
PDGVHRVRFALALRPGDHVVGFGERFDRLDQAGQRLDAVVFEQYKSQGRHGRTYLPMPFAHVVGADGESWGFHVRTSRRT
WYDVGASTPEALVVEVDLGTGGDIVDVGIYDGTPTEVLTEFLDEVGRAEELPEWVLRLWASGNEWNTQRLVMDRMDRHRE
LDIPVGVVVIEAWSDEEGITIFRDARYEPNPDGRAHDAADFAYPPDGAWPDPHGMVDDLHSRGIKVVLWQIPLQKTDPEL
TGQVRMDAEAMVREGHAVLEADGSAYHNRGWWFPRALMPDLSVQRTRDWWTAKRRYLLSDLDVDGFKTDGGEHAWGHDLR
YADGRRGDEGNNLFPVHYARAFGDLLRSEGKAPVTFSRAGFTGSQAHGVFWAGDEDSTWEAFRSSVTAGLTAAACGIIYW
GWDLAGFSGPVPDAELYLRAAGASVFMPVMQYHSEFNHHRPPLRDRTPWNVQEASGDERVVPVFRHFARMRERLVPYLAE
QARATVATDRPLMRPLFFDHPADPALWAHPLQWKLGDGMLVNPVTEPGATAWSTYLPAGQWVDAWTGTAYAGEQVVTAEE
LPLDRVPVYLAADAAPGLAAVFSE

Sequences:

>Translated_744_residues
MNPADRPPVTHRPHGIEHPYVQSADQRCPVLPLAGSTCRIGVTADPAVVAVRCEWGDQVLAMTPRTVDAADAAALAGGEG
HLAEAQANMLEADGAWTLETPVLVEGCRLTYRFVAVTADGVEVATPAYHVAPAVWSASHPGRLQGAADRLVPGSTSWLVS
PDGVHRVRFALALRPGDHVVGFGERFDRLDQAGQRLDAVVFEQYKSQGRHGRTYLPMPFAHVVGADGESWGFHVRTSRRT
WYDVGASTPEALVVEVDLGTGGDIVDVGIYDGTPTEVLTEFLDEVGRAEELPEWVLRLWASGNEWNTQRLVMDRMDRHRE
LDIPVGVVVIEAWSDEEGITIFRDARYEPNPDGRAHDAADFAYPPDGAWPDPHGMVDDLHSRGIKVVLWQIPLQKTDPEL
TGQVRMDAEAMVREGHAVLEADGSAYHNRGWWFPRALMPDLSVQRTRDWWTAKRRYLLSDLDVDGFKTDGGEHAWGHDLR
YADGRRGDEGNNLFPVHYARAFGDLLRSEGKAPVTFSRAGFTGSQAHGVFWAGDEDSTWEAFRSSVTAGLTAAACGIIYW
GWDLAGFSGPVPDAELYLRAAGASVFMPVMQYHSEFNHHRPPLRDRTPWNVQEASGDERVVPVFRHFARMRERLVPYLAE
QARATVATDRPLMRPLFFDHPADPALWAHPLQWKLGDGMLVNPVTEPGATAWSTYLPAGQWVDAWTGTAYAGEQVVTAEE
LPLDRVPVYLAADAAPGLAAVFSE
>Mature_744_residues
MNPADRPPVTHRPHGIEHPYVQSADQRCPVLPLAGSTCRIGVTADPAVVAVRCEWGDQVLAMTPRTVDAADAAALAGGEG
HLAEAQANMLEADGAWTLETPVLVEGCRLTYRFVAVTADGVEVATPAYHVAPAVWSASHPGRLQGAADRLVPGSTSWLVS
PDGVHRVRFALALRPGDHVVGFGERFDRLDQAGQRLDAVVFEQYKSQGRHGRTYLPMPFAHVVGADGESWGFHVRTSRRT
WYDVGASTPEALVVEVDLGTGGDIVDVGIYDGTPTEVLTEFLDEVGRAEELPEWVLRLWASGNEWNTQRLVMDRMDRHRE
LDIPVGVVVIEAWSDEEGITIFRDARYEPNPDGRAHDAADFAYPPDGAWPDPHGMVDDLHSRGIKVVLWQIPLQKTDPEL
TGQVRMDAEAMVREGHAVLEADGSAYHNRGWWFPRALMPDLSVQRTRDWWTAKRRYLLSDLDVDGFKTDGGEHAWGHDLR
YADGRRGDEGNNLFPVHYARAFGDLLRSEGKAPVTFSRAGFTGSQAHGVFWAGDEDSTWEAFRSSVTAGLTAAACGIIYW
GWDLAGFSGPVPDAELYLRAAGASVFMPVMQYHSEFNHHRPPLRDRTPWNVQEASGDERVVPVFRHFARMRERLVPYLAE
QARATVATDRPLMRPLFFDHPADPALWAHPLQWKLGDGMLVNPVTEPGATAWSTYLPAGQWVDAWTGTAYAGEQVVTAEE
LPLDRVPVYLAADAAPGLAAVFSE

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI66346737, Length=378, Percent_Identity=26.984126984127, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI38202257, Length=640, Percent_Identity=24.53125, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI88900491, Length=640, Percent_Identity=24.53125, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI221316699, Length=522, Percent_Identity=22.9885057471264, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI153791946, Length=375, Percent_Identity=28.5333333333333, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI119393895, Length=488, Percent_Identity=24.1803278688525, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI119393893, Length=488, Percent_Identity=24.1803278688525, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI119393891, Length=488, Percent_Identity=24.1803278688525, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI157364974, Length=464, Percent_Identity=21.551724137931, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310115361, Length=221, Percent_Identity=25.3393665158371, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI2367256, Length=549, Percent_Identity=26.0473588342441, Blast_Score=145, Evalue=9e-36,
Organism=Escherichia coli, GI2367323, Length=607, Percent_Identity=25.7001647446458, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71991189, Length=454, Percent_Identity=24.2290748898678, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560798, Length=379, Percent_Identity=26.9129287598945, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17560800, Length=379, Percent_Identity=26.9129287598945, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32563849, Length=200, Percent_Identity=28, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71985706, Length=211, Percent_Identity=25.5924170616114, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319706, Length=381, Percent_Identity=23.8845144356955, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24650054, Length=374, Percent_Identity=24.0641711229947, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24643749, Length=504, Percent_Identity=24.2063492063492, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24643753, Length=504, Percent_Identity=24.2063492063492, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24643751, Length=504, Percent_Identity=24.2063492063492, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24643746, Length=504, Percent_Identity=24.2063492063492, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357605, Length=504, Percent_Identity=24.2063492063492, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571440, Length=382, Percent_Identity=23.2984293193717, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571438, Length=382, Percent_Identity=23.2984293193717, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 82005; Mature: 82005

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPADRPPVTHRPHGIEHPYVQSADQRCPVLPLAGSTCRIGVTADPAVVAVRCEWGDQVL
CCCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEECCCEEEEEEECCCEEEEEEECCCCEEE
AMTPRTVDAADAAALAGGEGHLAEAQANMLEADGAWTLETPVLVEGCRLTYRFVAVTADG
EECCCCCCCCCHHHHCCCCCCCHHHHHHHEECCCCEEECCCCEEECCEEEEEEEEEEECC
VEVATPAYHVAPAVWSASHPGRLQGAADRLVPGSTSWLVSPDGVHRVRFALALRPGDHVV
CEECCCCHHHHHHHHCCCCCCCCCCCHHHCCCCCCCEEECCCCCEEEEEEEEECCCCCEE
GFGERFDRLDQAGQRLDAVVFEQYKSQGRHGRTYLPMPFAHVVGADGESWGFHVRTSRRT
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHCCCCCCCCCEEEEECCCE
WYDVGASTPEALVVEVDLGTGGDIVDVGIYDGTPTEVLTEFLDEVGRAEELPEWVLRLWA
EEECCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHC
SGNEWNTQRLVMDRMDRHRELDIPVGVVVIEAWSDEEGITIFRDARYEPNPDGRAHDAAD
CCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCC
FAYPPDGAWPDPHGMVDDLHSRGIKVVLWQIPLQKTDPELTGQVRMDAEAMVREGHAVLE
CCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEECHHHHHHCCCEEEE
ADGSAYHNRGWWFPRALMPDLSVQRTRDWWTAKRRYLLSDLDVDGFKTDGGEHAWGHDLR
ECCCEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCC
YADGRRGDEGNNLFPVHYARAFGDLLRSEGKAPVTFSRAGFTGSQAHGVFWAGDEDSTWE
CCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCHHH
AFRSSVTAGLTAAACGIIYWGWDLAGFSGPVPDAELYLRAAGASVFMPVMQYHSEFNHHR
HHHHHHHHHHHHHHHEEEEECCEECCCCCCCCCHHEEEEECCCHHHHHHHHHHHHHHCCC
PPLRDRTPWNVQEASGDERVVPVFRHFARMRERLVPYLAEQARATVATDRPLMRPLFFDH
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCC
PADPALWAHPLQWKLGDGMLVNPVTEPGATAWSTYLPAGQWVDAWTGTAYAGEQVVTAEE
CCCCCCCCCCCEEECCCCEEECCCCCCCCCHHHHHCCCCCEECCCCCCCCCCCEEEEHHH
LPLDRVPVYLAADAAPGLAAVFSE
CCCCCCCEEEEECCCCCHHHHHCC
>Mature Secondary Structure
MNPADRPPVTHRPHGIEHPYVQSADQRCPVLPLAGSTCRIGVTADPAVVAVRCEWGDQVL
CCCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEECCCEEEEEEECCCEEEEEEECCCCEEE
AMTPRTVDAADAAALAGGEGHLAEAQANMLEADGAWTLETPVLVEGCRLTYRFVAVTADG
EECCCCCCCCCHHHHCCCCCCCHHHHHHHEECCCCEEECCCCEEECCEEEEEEEEEEECC
VEVATPAYHVAPAVWSASHPGRLQGAADRLVPGSTSWLVSPDGVHRVRFALALRPGDHVV
CEECCCCHHHHHHHHCCCCCCCCCCCHHHCCCCCCCEEECCCCCEEEEEEEEECCCCCEE
GFGERFDRLDQAGQRLDAVVFEQYKSQGRHGRTYLPMPFAHVVGADGESWGFHVRTSRRT
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHCCCCCCCCCEEEEECCCE
WYDVGASTPEALVVEVDLGTGGDIVDVGIYDGTPTEVLTEFLDEVGRAEELPEWVLRLWA
EEECCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHC
SGNEWNTQRLVMDRMDRHRELDIPVGVVVIEAWSDEEGITIFRDARYEPNPDGRAHDAAD
CCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCC
FAYPPDGAWPDPHGMVDDLHSRGIKVVLWQIPLQKTDPELTGQVRMDAEAMVREGHAVLE
CCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEECHHHHHHCCCEEEE
ADGSAYHNRGWWFPRALMPDLSVQRTRDWWTAKRRYLLSDLDVDGFKTDGGEHAWGHDLR
ECCCEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCC
YADGRRGDEGNNLFPVHYARAFGDLLRSEGKAPVTFSRAGFTGSQAHGVFWAGDEDSTWE
CCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCHHH
AFRSSVTAGLTAAACGIIYWGWDLAGFSGPVPDAELYLRAAGASVFMPVMQYHSEFNHHR
HHHHHHHHHHHHHHHEEEEECCEECCCCCCCCCHHEEEEECCCHHHHHHHHHHHHHHCCC
PPLRDRTPWNVQEASGDERVVPVFRHFARMRERLVPYLAEQARATVATDRPLMRPLFFDH
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCC
PADPALWAHPLQWKLGDGMLVNPVTEPGATAWSTYLPAGQWVDAWTGTAYAGEQVVTAEE
CCCCCCCCCCCEEECCCCEEECCCCCCCCCHHHHHCCCCCEECCCCCCCCCCCEEEEHHH
LPLDRVPVYLAADAAPGLAAVFSE
CCCCCCCEEEEECCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]