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The map label for this gene is spoVD [H]

Identifier: 119718817

GI number: 119718817

Start: 4873046

End: 4874965

Strand: Reverse

Name: spoVD [H]

Synonym: Noca_4600

Alternate gene names: 119718817

Gene position: 4874965-4873046 (Counterclockwise)

Preceding gene: 119718818

Following gene: 119718815

Centisome position: 97.78

GC content: 75.31

Gene sequence:

>1920_bases
GTGCGGGCTGGTAGAACCGACGGCATGCGCCCGAGCCGCCGACTCCCGCTCGCCACCTTGGCCCTGCTGCTCGTGGGCAG
CGCACTGGTCGGCTGCGACGCCGCCGAGAAGGTGACCGGGCCCGACCCCGACGAGGCGGCGGCCGCGCTGGCCGAGGCCC
TGGTCTCCGGGGACTTCGGAGCGGTCGCGTTCACCGAGGGCGCCGCCGCGGACGTCGGCGCGGAGTACGCGAAGGTCGTC
GAGGGCATGGGCGAGGTGACGCCGGCGGTGACGGCCACCGGCACCGACGAGAGCGACGCCGGCGCCGCGACGGCGACGCT
GTCGTGGACCTGGTCGCTGGCCGGCGAGGAGTGGAGCTACACCACCCAGGCGCCGCTGACCGAGGCTGCCGACGAGTGGC
AGGTGACCTGGTCGCGGAAGGTCGTCGAGCCGAGCCTGGGCCCGGGGACGGTCCTCGACGTGACCCCGATCGGCGGCGGC
CGCGGCCCGGTGCTCGGGGCCGGCGGCGTCGCGCTCGTGACCGACCGTCCCGTGGTCCGCTTCGGCATCGACCGGTCGCA
GGTGCCCGCCGCCCGCGCCGCGGACGCCGCCCGGCGGCTGGCCCGGCTGGTGGGCGTCGACCCGGCGCCGTACGCCAAGC
AGGTCGAGGCGGCAGGCGAGCAGGCCTACGTCGAGGCGATCGTGTTCCGCAAGGACGACGTGCCCCTGGAGGTCGCGCGC
GGCTACCAGGCCATCCCCGGCGCGCTCGCCGTCCCCGACGACATCCCGCTGGCGCCGACCCGCGACTTCGCGGCGCCACT
CCTCGGCACGGTCGGCGCGGTGACCGCGGAGATGATCGAGAAGGAGCCGGACAAGTACAGGGTCGGGGACCAGGCCGGCC
TTTCCGGGCTGCAAGCGCGCTACGACGACCAGCTCCAGGGCACCGACGGCGTCGTGGTCGACGCCGTCGCCTCCGACGGG
CGCGAGCGACAGCTGTTCCGGGTCGATGCGAAGCAGGGGGAGCCGCTCGAGCTCACCCTCGACGAGCGGCTCCAGCTCGC
CGCCGAGCGCGCGCTCGCCGGCGTCGGACCCGCCAGCGCCCTGGTGGCGCTGCGGACCTCGACCGGCGCGATCCTGGCCG
CGGCCAACGGGCCCGGCAACGACGGCTACAACCTGGCGACCTACGGCCAGCTCGCCCCCGGGTCGACGTTCAAGAGCGTG
AGCAGCCTGGCGCTGCTGCGCGCCGGGCTCACGCCGCAGAGTGTGGTGCCCTGCACGCCGTCGATCGTCGTGGACGGCAA
GCGGTTCGAGAACTACGACGACTACCCCAGCGGCGCCCTGGGCGACATCGCGCTGCGCACCGCGATCGCGAACTCGTGCA
ACACGGCGGTGATCTCCCAGCGCGACAAGCTCGGTGCCGGCGACCTCGCCGCCGCCGCGGCGTCGCTCGGGCTCGGCATC
GACCACGACCTGGGCTTCCCGGCGTACTTCGGCAGCGTCGAGCCGCCGGCCTCGGAGACCGAGGCCGCCGCGGACCTGAT
CGGCCAGGGCCGGGTGCTCGCCTCACCGATGGCGATGGCCACGGTGATCGCATCCGTGCAGGCCGGCCACACCGTGGTGC
CCCGGCTGGTCGAGTCCGTCGACGTGTCGGTGCCCGACCGGGCGAAGCCGCTGAGCGGGTCCGAGGCCGCCGCCCTGCGC
TCGATGCTCCGCGCCGTGGTCACCTCGGGCAGCGGCGCCGGCCTGCTCGACGTGCCCGGCCCGCCGGTGATCGCCAAGAC
CGGGACGGCGGAGTTCGAGCGCGGCGGCAAGCTGCTGACCCACGCGTGGATGATCGCCGCTCAGGGCGACCTCGCGGTGG
CCGTGTTCGTCGACCTCGGCTCCTCCGGCTCCGGCACCGCCGGCCCGATCCTCGAGGCGTTCCTCCGCGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
CGGCCGACACCCGACACAAGAAGCCCCGCCACAAGACCCGTTGAATCGGGAGTTCCGCGCCTCGAGTCGGAAGTCCCGAC
TCGACATCGGGGGTGGGTCG

Downstream 100 bases:

>100_bases
CCGGGGATCGGTTTCCCCGGTGAACCGGGGATGTTGGAACTTCTGGCCCGAAGTTTCGGCCCAACAGTTCCGGTTTCCCC
GGTTAACCGGGGAAACCGCC

Product: penicillin-binding protein, transpeptidase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MRAGRTDGMRPSRRLPLATLALLLVGSALVGCDAAEKVTGPDPDEAAAALAEALVSGDFGAVAFTEGAAADVGAEYAKVV
EGMGEVTPAVTATGTDESDAGAATATLSWTWSLAGEEWSYTTQAPLTEAADEWQVTWSRKVVEPSLGPGTVLDVTPIGGG
RGPVLGAGGVALVTDRPVVRFGIDRSQVPAARAADAARRLARLVGVDPAPYAKQVEAAGEQAYVEAIVFRKDDVPLEVAR
GYQAIPGALAVPDDIPLAPTRDFAAPLLGTVGAVTAEMIEKEPDKYRVGDQAGLSGLQARYDDQLQGTDGVVVDAVASDG
RERQLFRVDAKQGEPLELTLDERLQLAAERALAGVGPASALVALRTSTGAILAAANGPGNDGYNLATYGQLAPGSTFKSV
SSLALLRAGLTPQSVVPCTPSIVVDGKRFENYDDYPSGALGDIALRTAIANSCNTAVISQRDKLGAGDLAAAAASLGLGI
DHDLGFPAYFGSVEPPASETEAAADLIGQGRVLASPMAMATVIASVQAGHTVVPRLVESVDVSVPDRAKPLSGSEAAALR
SMLRAVVTSGSGAGLLDVPGPPVIAKTGTAEFERGGKLLTHAWMIAAQGDLAVAVFVDLGSSGSGTAGPILEAFLRAAR

Sequences:

>Translated_639_residues
MRAGRTDGMRPSRRLPLATLALLLVGSALVGCDAAEKVTGPDPDEAAAALAEALVSGDFGAVAFTEGAAADVGAEYAKVV
EGMGEVTPAVTATGTDESDAGAATATLSWTWSLAGEEWSYTTQAPLTEAADEWQVTWSRKVVEPSLGPGTVLDVTPIGGG
RGPVLGAGGVALVTDRPVVRFGIDRSQVPAARAADAARRLARLVGVDPAPYAKQVEAAGEQAYVEAIVFRKDDVPLEVAR
GYQAIPGALAVPDDIPLAPTRDFAAPLLGTVGAVTAEMIEKEPDKYRVGDQAGLSGLQARYDDQLQGTDGVVVDAVASDG
RERQLFRVDAKQGEPLELTLDERLQLAAERALAGVGPASALVALRTSTGAILAAANGPGNDGYNLATYGQLAPGSTFKSV
SSLALLRAGLTPQSVVPCTPSIVVDGKRFENYDDYPSGALGDIALRTAIANSCNTAVISQRDKLGAGDLAAAAASLGLGI
DHDLGFPAYFGSVEPPASETEAAADLIGQGRVLASPMAMATVIASVQAGHTVVPRLVESVDVSVPDRAKPLSGSEAAALR
SMLRAVVTSGSGAGLLDVPGPPVIAKTGTAEFERGGKLLTHAWMIAAQGDLAVAVFVDLGSSGSGTAGPILEAFLRAAR
>Mature_639_residues
MRAGRTDGMRPSRRLPLATLALLLVGSALVGCDAAEKVTGPDPDEAAAALAEALVSGDFGAVAFTEGAAADVGAEYAKVV
EGMGEVTPAVTATGTDESDAGAATATLSWTWSLAGEEWSYTTQAPLTEAADEWQVTWSRKVVEPSLGPGTVLDVTPIGGG
RGPVLGAGGVALVTDRPVVRFGIDRSQVPAARAADAARRLARLVGVDPAPYAKQVEAAGEQAYVEAIVFRKDDVPLEVAR
GYQAIPGALAVPDDIPLAPTRDFAAPLLGTVGAVTAEMIEKEPDKYRVGDQAGLSGLQARYDDQLQGTDGVVVDAVASDG
RERQLFRVDAKQGEPLELTLDERLQLAAERALAGVGPASALVALRTSTGAILAAANGPGNDGYNLATYGQLAPGSTFKSV
SSLALLRAGLTPQSVVPCTPSIVVDGKRFENYDDYPSGALGDIALRTAIANSCNTAVISQRDKLGAGDLAAAAASLGLGI
DHDLGFPAYFGSVEPPASETEAAADLIGQGRVLASPMAMATVIASVQAGHTVVPRLVESVDVSVPDRAKPLSGSEAAALR
SMLRAVVTSGSGAGLLDVPGPPVIAKTGTAEFERGGKLLTHAWMIAAQGDLAVAVFVDLGSSGSGTAGPILEAFLRAAR

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=341, Percent_Identity=24.3401759530792, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65085; Mature: 65085

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGRTDGMRPSRRLPLATLALLLVGSALVGCDAAEKVTGPDPDEAAAALAEALVSGDFG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHCCCCC
AVAFTEGAAADVGAEYAKVVEGMGEVTPAVTATGTDESDAGAATATLSWTWSLAGEEWSY
EEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEEEEEECCCCCCC
TTQAPLTEAADEWQVTWSRKVVEPSLGPGTVLDVTPIGGGRGPVLGAGGVALVTDRPVVR
CCCCCCHHCCCCCEEEECCEEECCCCCCCCEEEEEECCCCCCCEECCCCEEEEECCCEEE
FGIDRSQVPAARAADAARRLARLVGVDPAPYAKQVEAAGEQAYVEAIVFRKDDVPLEVAR
ECCCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHEEEEEEEECCCCCHHHHC
GYQAIPGALAVPDDIPLAPTRDFAAPLLGTVGAVTAEMIEKEPDKYRVGDQAGLSGLQAR
CCHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHCCHHHHHH
YDDQLQGTDGVVVDAVASDGRERQLFRVDAKQGEPLELTLDERLQLAAERALAGVGPASA
CCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCCHHHH
LVALRTSTGAILAAANGPGNDGYNLATYGQLAPGSTFKSVSSLALLRAGLTPQSVVPCTP
EEEEEECCCEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
SIVVDGKRFENYDDYPSGALGDIALRTAIANSCNTAVISQRDKLGAGDLAAAAASLGLGI
CEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHCCCC
DHDLGFPAYFGSVEPPASETEAAADLIGQGRVLASPMAMATVIASVQAGHTVVPRLVESV
CCCCCCCHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
DVSVPDRAKPLSGSEAAALRSMLRAVVTSGSGAGLLDVPGPPVIAKTGTAEFERGGKLLT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCHHHHHCCCEEE
HAWMIAAQGDLAVAVFVDLGSSGSGTAGPILEAFLRAAR
EEEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRAGRTDGMRPSRRLPLATLALLLVGSALVGCDAAEKVTGPDPDEAAAALAEALVSGDFG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHCCCCC
AVAFTEGAAADVGAEYAKVVEGMGEVTPAVTATGTDESDAGAATATLSWTWSLAGEEWSY
EEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEEEEEECCCCCCC
TTQAPLTEAADEWQVTWSRKVVEPSLGPGTVLDVTPIGGGRGPVLGAGGVALVTDRPVVR
CCCCCCHHCCCCCEEEECCEEECCCCCCCCEEEEEECCCCCCCEECCCCEEEEECCCEEE
FGIDRSQVPAARAADAARRLARLVGVDPAPYAKQVEAAGEQAYVEAIVFRKDDVPLEVAR
ECCCHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHEEEEEEEECCCCCHHHHC
GYQAIPGALAVPDDIPLAPTRDFAAPLLGTVGAVTAEMIEKEPDKYRVGDQAGLSGLQAR
CCHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHCCHHHHHH
YDDQLQGTDGVVVDAVASDGRERQLFRVDAKQGEPLELTLDERLQLAAERALAGVGPASA
CCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCCHHHH
LVALRTSTGAILAAANGPGNDGYNLATYGQLAPGSTFKSVSSLALLRAGLTPQSVVPCTP
EEEEEECCCEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
SIVVDGKRFENYDDYPSGALGDIALRTAIANSCNTAVISQRDKLGAGDLAAAAASLGLGI
CEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHCCCC
DHDLGFPAYFGSVEPPASETEAAADLIGQGRVLASPMAMATVIASVQAGHTVVPRLVESV
CCCCCCCHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
DVSVPDRAKPLSGSEAAALRSMLRAVVTSGSGAGLLDVPGPPVIAKTGTAEFERGGKLLT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCHHHHHCCCEEE
HAWMIAAQGDLAVAVFVDLGSSGSGTAGPILEAFLRAAR
EEEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]