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The map label for this gene is srpA [H]

Identifier: 119718562

GI number: 119718562

Start: 4591611

End: 4592522

Strand: Reverse

Name: srpA [H]

Synonym: Noca_4343

Alternate gene names: 119718562

Gene position: 4592522-4591611 (Counterclockwise)

Preceding gene: 119718563

Following gene: 119718561

Centisome position: 92.11

GC content: 74.78

Gene sequence:

>912_bases
ATGCCCGACCCGACTGCCCCCGAACCGGCGGGGCTCGATCCCGCGGCCGCGATCGACCGCCTGCGCGCGGCGTTCCGCGG
CCCCGCCGCCCATCGCACCCTGCACGCGAAGGGCCGGTTCTACGCCGGCACCTTCACCCCGACCCCGGAGGCCGGCGAGC
TGTGCCGGGCCGGCCACCTCCGCGCACCCACGCCGGTCCTCGTCCGCTGGTCGAACGCCGGCGGTAACGCCGCCGTGCCC
GACCCGACCCCGGACATCCGCGGGATGGCGGTGAAATTCCGGCTCGCCGACGGCACCGCGACCGACCTGCTCGGCCAGAC
CTCCCCGCGGTTCCCGACCGACGACCCGGAGGAGTTCGTCGCGATGACCGAGGCGTCGGTGAGGCCGTTGACCTTTCCGT
TCTTCCTGGCCCGGCACCCGCGGCTGCTGCCGAGCGTGCTCGCGAGCCTGCGCGCCCACGCCGTCTCGGCACCGGTCAGC
TTCGCGGAGCCGGCGTACTTCCCGATCCATGCCTATGGGTGGCTCGACGACGCCGGCCGGCGGGCCTGGGTGCGCTATGC
CTTCGTGCCGCAGGCGAGCGCGGCCGACCGGCTGCCGGAGCGGTTCGAGGGGCCGGACCGGCTCTTCGAGGAGATGGCCG
CTCGGCTCGAGCGGGGTCCGGTCACCCACGAGGTGCGGGTCCAGGTCGCCGGCCCGGGCCACGACCCGCACTCGGCGACG
TCGGTCTGGAAGGGCGCCCGCGAGCTGGTCGCCGGGCACCTCGTCGTCCACGAGCCGTTGCCGGACCAGGAGGCGGACGG
CCCGGTCGTCTTCGACCCGACCCGGGTGGTGGACGGTATCGAGCTCTCCGACGATCCCATCCTGCGATACCGACCGGCGG
CCTACACCGAGTCCGTCTCCCGCCGCGGATAG

Upstream 100 bases:

>100_bases
GTCGAGGAGATGTCCGGTGCCCGGATCTCCGCGGTCGGCGTCGGGCCGTCCCGCGACGCGACCGTCGCCATCCACGACCT
GATCTGAGACCGTTCGGGTC

Downstream 100 bases:

>100_bases
GGTTGCGGCCCGTGAAGACCCTCGTCATCGGCACCGGCGGACGCGAACACGCACTGGCCCGCGCGCTCTCCCAGGACCCC
GCCGTGACCGAGGTGCACGC

Product: catalase domain-containing protein

Products: H2O; O2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPDPTAPEPAGLDPAAAIDRLRAAFRGPAAHRTLHAKGRFYAGTFTPTPEAGELCRAGHLRAPTPVLVRWSNAGGNAAVP
DPTPDIRGMAVKFRLADGTATDLLGQTSPRFPTDDPEEFVAMTEASVRPLTFPFFLARHPRLLPSVLASLRAHAVSAPVS
FAEPAYFPIHAYGWLDDAGRRAWVRYAFVPQASAADRLPERFEGPDRLFEEMAARLERGPVTHEVRVQVAGPGHDPHSAT
SVWKGARELVAGHLVVHEPLPDQEADGPVVFDPTRVVDGIELSDDPILRYRPAAYTESVSRRG

Sequences:

>Translated_303_residues
MPDPTAPEPAGLDPAAAIDRLRAAFRGPAAHRTLHAKGRFYAGTFTPTPEAGELCRAGHLRAPTPVLVRWSNAGGNAAVP
DPTPDIRGMAVKFRLADGTATDLLGQTSPRFPTDDPEEFVAMTEASVRPLTFPFFLARHPRLLPSVLASLRAHAVSAPVS
FAEPAYFPIHAYGWLDDAGRRAWVRYAFVPQASAADRLPERFEGPDRLFEEMAARLERGPVTHEVRVQVAGPGHDPHSAT
SVWKGARELVAGHLVVHEPLPDQEADGPVVFDPTRVVDGIELSDDPILRYRPAAYTESVSRRG
>Mature_302_residues
PDPTAPEPAGLDPAAAIDRLRAAFRGPAAHRTLHAKGRFYAGTFTPTPEAGELCRAGHLRAPTPVLVRWSNAGGNAAVPD
PTPDIRGMAVKFRLADGTATDLLGQTSPRFPTDDPEEFVAMTEASVRPLTFPFFLARHPRLLPSVLASLRAHAVSAPVSF
AEPAYFPIHAYGWLDDAGRRAWVRYAFVPQASAADRLPERFEGPDRLFEEMAARLERGPVTHEVRVQVAGPGHDPHSATS
VWKGARELVAGHLVVHEPLPDQEADGPVVFDPTRVVDGIELSDDPILRYRPAAYTESVSRRG

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Escherichia coli, GI48994891, Length=305, Percent_Identity=26.8852459016393, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71998444, Length=318, Percent_Identity=25.4716981132075, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6 [C]

Molecular weight: Translated: 32887; Mature: 32756

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPTAPEPAGLDPAAAIDRLRAAFRGPAAHRTLHAKGRFYAGTFTPTPEAGELCRAGHL
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCEEECCCCEEEECCCCCCCHHHHHHCCCC
RAPTPVLVRWSNAGGNAAVPDPTPDIRGMAVKFRLADGTATDLLGQTSPRFPTDDPEEFV
CCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCHHHHH
AMTEASVRPLTFPFFLARHPRLLPSVLASLRAHAVSAPVSFAEPAYFPIHAYGWLDDAGR
HHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCC
RAWVRYAFVPQASAADRLPERFEGPDRLFEEMAARLERGPVTHEVRVQVAGPGHDPHSAT
EEEEEEEECCCCCHHHHCHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHH
SVWKGARELVAGHLVVHEPLPDQEADGPVVFDPTRVVDGIELSDDPILRYRPAAYTESVS
HHHHHHHHHHHCCEEEECCCCCCCCCCCEEECCHHHHCCCCCCCCCCEEECCCHHHHHHH
RRG
CCC
>Mature Secondary Structure 
PDPTAPEPAGLDPAAAIDRLRAAFRGPAAHRTLHAKGRFYAGTFTPTPEAGELCRAGHL
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCEEECCCCEEEECCCCCCCHHHHHHCCCC
RAPTPVLVRWSNAGGNAAVPDPTPDIRGMAVKFRLADGTATDLLGQTSPRFPTDDPEEFV
CCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCHHHHH
AMTEASVRPLTFPFFLARHPRLLPSVLASLRAHAVSAPVSFAEPAYFPIHAYGWLDDAGR
HHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCC
RAWVRYAFVPQASAADRLPERFEGPDRLFEEMAARLERGPVTHEVRVQVAGPGHDPHSAT
EEEEEEEECCCCCHHHHCHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHH
SVWKGARELVAGHLVVHEPLPDQEADGPVVFDPTRVVDGIELSDDPILRYRPAAYTESVS
HHHHHHHHHHHCCEEEECCCCCCCCCCCEEECCHHHHCCCCCCCCCCEEECCCHHHHHHH
RRG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: Hydrogen peroxide [C]

Specific reaction: (2) Hydrogen peroxide --> (2) H2O + O2 [C]

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]