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The map label for this gene is fur [H]

Identifier: 119718470

GI number: 119718470

Start: 4489862

End: 4490281

Strand: Reverse

Name: fur [H]

Synonym: Noca_4251

Alternate gene names: 119718470

Gene position: 4490281-4489862 (Counterclockwise)

Preceding gene: 119718471

Following gene: 119718469

Centisome position: 90.06

GC content: 70.24

Gene sequence:

>420_bases
GTGACCGAGGAGCTCGCGGCGCGGCTGCGGGAGCAGGGCTACCGACTCACCCCGCAGCGCCAGCTGGTGCTGCAGGCGGT
CGAGAAGCTCGGCCACGCGACGCCGGACGAGGTGCTCGCCGAGGTGCACGCCCAGTCCAGCGCGGTCAACGTCTCCACGA
TCTACCGCACCCTGGAGGTGCTCGAGGAGCTCGGCCTGGTGCGGCACGCGCACCTGTCCGACCGGGCGCCGACGTACCAC
TCGGTGACCGACCGCGAGCACTTCCACCTGGTCTGCCGGAATTGCCACAAGGTCGTCTCCGTTGACCCAGAAGTGATCGG
GCCGCTCGCCGAGCGGCTCGTGCGCGACCATGGCTTCGTCATCGACGTGGGCCACCTGGCGGTCTTCGGCCGCTGCACCG
ACTGCGAGGAGGACCGATGA

Upstream 100 bases:

>100_bases
CCATGGGCCAGCCGCTCCAGCCGCACCTGTGGGCGCGGCTGGTCCGGCAGTGACCCCCGGCGCGTGAGCCCAGGACCACC
ACGACCATGAGGCAGGAGCA

Downstream 100 bases:

>100_bases
GGAGCCCGCTGCTGGACCTGCCCGGAGCCGTGGCCGGGGACGGCGTCGACCGTGACGTGGCCGCGCACTACGGCTCGTTC
AACGGCGAGCAGCGCACCCT

Product: FUR family nickel uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MTEELAARLREQGYRLTPQRQLVLQAVEKLGHATPDEVLAEVHAQSSAVNVSTIYRTLEVLEELGLVRHAHLSDRAPTYH
SVTDREHFHLVCRNCHKVVSVDPEVIGPLAERLVRDHGFVIDVGHLAVFGRCTDCEEDR

Sequences:

>Translated_139_residues
MTEELAARLREQGYRLTPQRQLVLQAVEKLGHATPDEVLAEVHAQSSAVNVSTIYRTLEVLEELGLVRHAHLSDRAPTYH
SVTDREHFHLVCRNCHKVVSVDPEVIGPLAERLVRDHGFVIDVGHLAVFGRCTDCEEDR
>Mature_138_residues
TEELAARLREQGYRLTPQRQLVLQAVEKLGHATPDEVLAEVHAQSSAVNVSTIYRTLEVLEELGLVRHAHLSDRAPTYHS
VTDREHFHLVCRNCHKVVSVDPEVIGPLAERLVRDHGFVIDVGHLAVFGRCTDCEEDR

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15681; Mature: 15550

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEELAARLREQGYRLTPQRQLVLQAVEKLGHATPDEVLAEVHAQSSAVNVSTIYRTLEV
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
LEELGLVRHAHLSDRAPTYHSVTDREHFHLVCRNCHKVVSVDPEVIGPLAERLVRDHGFV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCE
IDVGHLAVFGRCTDCEEDR
EEHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TEELAARLREQGYRLTPQRQLVLQAVEKLGHATPDEVLAEVHAQSSAVNVSTIYRTLEV
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
LEELGLVRHAHLSDRAPTYHSVTDREHFHLVCRNCHKVVSVDPEVIGPLAERLVRDHGFV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCE
IDVGHLAVFGRCTDCEEDR
EEHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]