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The map label for this gene is paaG [H]

Identifier: 119718360

GI number: 119718360

Start: 4372974

End: 4373723

Strand: Reverse

Name: paaG [H]

Synonym: Noca_4141

Alternate gene names: 119718360

Gene position: 4373723-4372974 (Counterclockwise)

Preceding gene: 119718361

Following gene: 119718355

Centisome position: 87.72

GC content: 76.53

Gene sequence:

>750_bases
ATGAGCGGGACCGTGCGCTACGAGCTCACCGACGGCGTCGCCCACCTGGTCCTCGACCGTCCCGACGCCGCCAACGCGAT
CGACATGGACACCGCGCTCGCCCTCGGCGACGCCGTCGACACCGCAGTGGCCGACGACGCCGTTCGGGTGCTGCTGCTGA
CCGGCGCCGGACCGCGCTTCTGCGCCGGCGGCGACGTGGCGTGGATGCTCGGGGACGACGACCGCGGCGCCCGGGTCGAG
GCGCTGGCCACGGTCCTCGACGGCGTCCTCGTCCGGCTCCACTCCTGCGCCAAGCCCGTCGTCGCCGCGGTGCAGGGAGC
GGTCGCCGGCGCCGGCCTCGCCGTGATGCTGAGCTGCGACGTGGTGGTCGCCGAGCCGGCCACGAAGTTCGTCGCGGCCT
ACGCGGCGGTCGGGCTCTCGCCCGACTGCGGCGTGTCCTGGCTGCTGCCGCGCGCCGTCGGGCAGCAACGCGCGCTCGAG
ATGCTGCTCGCTCAGCGCGTCGTCACTGCCGACGAGGCGCTCGCGTGGGGCCTGGTCGGGCAGGTCGCCGACGACCCGGC
TGCCGCCGCGGCCGAGCTGGCCGCGCGGATGGCCGCGGGCCCGGCGTACGCGCTCGGGCAGACGCGGCGCCTGGTGCGCG
ACGCGTGGGTGCGTGACCGGGGCGCCAGTGGCGCCGACGAGACCCGGACCATCACCCGGGCCGTGCAGACGCCGGAGGCG
GACCGGCTGCTCAGCCGTTTCCTCGCGTAG

Upstream 100 bases:

>100_bases
GAGTCGCCAAGGACCTGGTCCGCCGCGATCTCGAGCTCGGCATCGTGACGATGTGCATCGGCGGCGGGCAGGCCCTCGCC
GCACTCTTCCGGAGAGTGTG

Downstream 100 bases:

>100_bases
CCCGGCCACCCAGGCACGGCGACGTGCCGACCGGCCACGGCAACGCGGCGTGCTCAGCCACCCAGCCGTCGAGCGCGGTC
GCGACGATGGCCGGCCAGAC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSGTVRYELTDGVAHLVLDRPDAANAIDMDTALALGDAVDTAVADDAVRVLLLTGAGPRFCAGGDVAWMLGDDDRGARVE
ALATVLDGVLVRLHSCAKPVVAAVQGAVAGAGLAVMLSCDVVVAEPATKFVAAYAAVGLSPDCGVSWLLPRAVGQQRALE
MLLAQRVVTADEALAWGLVGQVADDPAAAAAELAARMAAGPAYALGQTRRLVRDAWVRDRGASGADETRTITRAVQTPEA
DRLLSRFLA

Sequences:

>Translated_249_residues
MSGTVRYELTDGVAHLVLDRPDAANAIDMDTALALGDAVDTAVADDAVRVLLLTGAGPRFCAGGDVAWMLGDDDRGARVE
ALATVLDGVLVRLHSCAKPVVAAVQGAVAGAGLAVMLSCDVVVAEPATKFVAAYAAVGLSPDCGVSWLLPRAVGQQRALE
MLLAQRVVTADEALAWGLVGQVADDPAAAAAELAARMAAGPAYALGQTRRLVRDAWVRDRGASGADETRTITRAVQTPEA
DRLLSRFLA
>Mature_248_residues
SGTVRYELTDGVAHLVLDRPDAANAIDMDTALALGDAVDTAVADDAVRVLLLTGAGPRFCAGGDVAWMLGDDDRGARVEA
LATVLDGVLVRLHSCAKPVVAAVQGAVAGAGLAVMLSCDVVVAEPATKFVAAYAAVGLSPDCGVSWLLPRAVGQQRALEM
LLAQRVVTADEALAWGLVGQVADDPAAAAAELAARMAAGPAYALGQTRRLVRDAWVRDRGASGADETRTITRAVQTPEAD
RLLSRFLA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4757968, Length=176, Percent_Identity=34.6590909090909, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI49355787, Length=176, Percent_Identity=34.6590909090909, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI25453481, Length=176, Percent_Identity=34.0909090909091, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI51538573, Length=176, Percent_Identity=34.0909090909091, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI221307494, Length=209, Percent_Identity=31.1004784688995, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI4757966, Length=176, Percent_Identity=34.0909090909091, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI51538581, Length=176, Percent_Identity=34.0909090909091, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI221136756, Length=209, Percent_Identity=31.1004784688995, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI221136753, Length=209, Percent_Identity=31.1004784688995, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI116235487, Length=215, Percent_Identity=31.1627906976744, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI260274832, Length=229, Percent_Identity=25.764192139738, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI45643119, Length=229, Percent_Identity=25.764192139738, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI260275230, Length=229, Percent_Identity=25.764192139738, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI70995211, Length=183, Percent_Identity=30.6010928961749, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI31542718, Length=205, Percent_Identity=29.7560975609756, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI68989263, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI194097323, Length=173, Percent_Identity=30.635838150289, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI20127408, Length=184, Percent_Identity=29.3478260869565, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787660, Length=222, Percent_Identity=36.9369369369369, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1787659, Length=239, Percent_Identity=31.3807531380753, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI221142681, Length=221, Percent_Identity=29.8642533936652, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788597, Length=186, Percent_Identity=37.0967741935484, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790281, Length=175, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=197, Percent_Identity=31.9796954314721, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=213, Percent_Identity=29.1079812206573, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=183, Percent_Identity=31.1475409836066, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=208, Percent_Identity=25.9615384615385, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554946, Length=194, Percent_Identity=29.3814432989691, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25145438, Length=212, Percent_Identity=29.7169811320755, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=229, Percent_Identity=26.6375545851528, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=141, Percent_Identity=31.9148936170213, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24654903, Length=229, Percent_Identity=24.8908296943231, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI20129971, Length=193, Percent_Identity=28.4974093264249, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653477, Length=193, Percent_Identity=28.4974093264249, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357171, Length=241, Percent_Identity=31.5352697095436, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920382, Length=200, Percent_Identity=30.5, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24653139, Length=173, Percent_Identity=30.635838150289, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24650670, Length=211, Percent_Identity=30.8056872037915, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 25641; Mature: 25509

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTVRYELTDGVAHLVLDRPDAANAIDMDTALALGDAVDTAVADDAVRVLLLTGAGPRF
CCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCE
CAGGDVAWMLGDDDRGARVEALATVLDGVLVRLHSCAKPVVAAVQGAVAGAGLAVMLSCD
ECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC
VVVAEPATKFVAAYAAVGLSPDCGVSWLLPRAVGQQRALEMLLAQRVVTADEALAWGLVG
EEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADDPAAAAAELAARMAAGPAYALGQTRRLVRDAWVRDRGASGADETRTITRAVQTPEA
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCH
DRLLSRFLA
HHHHHHHCC
>Mature Secondary Structure 
SGTVRYELTDGVAHLVLDRPDAANAIDMDTALALGDAVDTAVADDAVRVLLLTGAGPRF
CCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCE
CAGGDVAWMLGDDDRGARVEALATVLDGVLVRLHSCAKPVVAAVQGAVAGAGLAVMLSCD
ECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC
VVVAEPATKFVAAYAAVGLSPDCGVSWLLPRAVGQQRALEMLLAQRVVTADEALAWGLVG
EEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADDPAAAAAELAARMAAGPAYALGQTRRLVRDAWVRDRGASGADETRTITRAVQTPEA
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCH
DRLLSRFLA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]