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The map label for this gene is acdA [H]

Identifier: 119718353

GI number: 119718353

Start: 4365647

End: 4366888

Strand: Reverse

Name: acdA [H]

Synonym: Noca_4134

Alternate gene names: 119718353

Gene position: 4366888-4365647 (Counterclockwise)

Preceding gene: 119718354

Following gene: 119718352

Centisome position: 87.59

GC content: 72.14

Gene sequence:

>1242_bases
ATGATCCCGCTCGAGGAGTTCCGGGCCGAGGCGGAGGCGTTCCTCGCGGCGAGCGGGCTCCCGCGTCGCGACGAGGACGA
GACGATCGTCTGGGGCGAGGGTGAGCTCGACGTCTCGGTCTTCCACAACCTGACCTTCGAGGAGGAGTCCGCGCTCCTCG
GGGAGCTCAAGGACTGGCAGCGCCGCAAGCTCGAGGCGGGCTTCGGCGCGATCACCTGGGAGCCGGAGTACGGCGGCCGT
GGGCTCGGCGCCGAGCACCTCGACGCCTTCGACGAGCTCGAGGCGCGCTACGAGACCCCGCGTCCCCACGAGACGTTCTC
GGTGACCCAGCACCTGATCGCGCCCACCGTCCGGCTGTTCGGCACCGAGGCGATGCGCACCGAGCTGATCCCGGCCTTCC
TCCGTGGCGAGCGGATCTGCTGCCAGCTCTTCTCCGAGCCCTCGGCCGGGTCCGACCTCGCCGCGCTCGGCACCCGCGCC
GTACGCGAGGGCGACGAGTGGGTCATCAACGGGCAGAAGGTGTGGAGCTCCGGAGCGCAGTTCGCCGACTGGGGCGAGCT
GATCTGCCGCAGCGACCCGACCCAGCCCAAGCACGCGGGGATGACCGCGTTCATGATCCCGATGGACTGGCCCGGGGTGG
AGGTCCGCCCGCTGCGGCAGATGTCCGGCGGCAGCAGCTTCAGCGAGGTCTTCCTCACCGACGTGCGGCTGCCCGACTCC
CACCGGATCGGCGACATCGGCGAGGGCTGGAAGGTCGCCCTGACCACGCTCGGCTTCGAGCGGCAGGCCGCCAACAACAA
CGCGCACGTCGGCGGCAACTGGCGCCAGCTGCTCGCCACGGCCCAGTGGGCGGACGTGTTGGACGACCCGTTCGTCCGCC
AGGACCTCGCCAAGGCCGTCATCAGCGAGCGTCTCGGCGCCGTCGCCGTGGCCCGTGACCAGGCGGCCCGCGAGAGCGGC
GAGCCGATGGGCGCGATCGGCTCGATCCGGATGATGCAGTGGGTCGGCCGGATGCTCGACGTCACCGCCGCCGCCCGCCG
CATCCTCGGGCCCCGGCTGGTCGTCGACCACGGCGACTGGGGGACCTACGTGTGGGGTGAGCACGTGCTGGGCGCCCCCG
GCTACCGGATCGCCGGCGGCTCCGACGAGATCCAGCGCACGATCATCGCCGAGCGCTGGCTCGGCATGCCGGCCGAGCCG
CGCGCCGACAAGGACACCCCGTGGAAGGACCTGCCCCGGTGA

Upstream 100 bases:

>100_bases
GGGTCCAGGCCGGCCTCGACCTCACCGTGGAGCTGGAGGGCGCGGCGAAACCGGCCTGCGTCGCCCGGATGCTGGCGCGC
TTCTACTTCCCGGAGGACGC

Downstream 100 bases:

>100_bases
CTTCAACCTCGAGCCCAGCTTCGAGCCCGACCACTGGCTCCCCGGCCCAGCCCCTGCTCGGCAAGGTCGCCCTCGTGACC
GGCGGCAGCCGTGGCCTCGG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MIPLEEFRAEAEAFLAASGLPRRDEDETIVWGEGELDVSVFHNLTFEEESALLGELKDWQRRKLEAGFGAITWEPEYGGR
GLGAEHLDAFDELEARYETPRPHETFSVTQHLIAPTVRLFGTEAMRTELIPAFLRGERICCQLFSEPSAGSDLAALGTRA
VREGDEWVINGQKVWSSGAQFADWGELICRSDPTQPKHAGMTAFMIPMDWPGVEVRPLRQMSGGSSFSEVFLTDVRLPDS
HRIGDIGEGWKVALTTLGFERQAANNNAHVGGNWRQLLATAQWADVLDDPFVRQDLAKAVISERLGAVAVARDQAARESG
EPMGAIGSIRMMQWVGRMLDVTAAARRILGPRLVVDHGDWGTYVWGEHVLGAPGYRIAGGSDEIQRTIIAERWLGMPAEP
RADKDTPWKDLPR

Sequences:

>Translated_413_residues
MIPLEEFRAEAEAFLAASGLPRRDEDETIVWGEGELDVSVFHNLTFEEESALLGELKDWQRRKLEAGFGAITWEPEYGGR
GLGAEHLDAFDELEARYETPRPHETFSVTQHLIAPTVRLFGTEAMRTELIPAFLRGERICCQLFSEPSAGSDLAALGTRA
VREGDEWVINGQKVWSSGAQFADWGELICRSDPTQPKHAGMTAFMIPMDWPGVEVRPLRQMSGGSSFSEVFLTDVRLPDS
HRIGDIGEGWKVALTTLGFERQAANNNAHVGGNWRQLLATAQWADVLDDPFVRQDLAKAVISERLGAVAVARDQAARESG
EPMGAIGSIRMMQWVGRMLDVTAAARRILGPRLVVDHGDWGTYVWGEHVLGAPGYRIAGGSDEIQRTIIAERWLGMPAEP
RADKDTPWKDLPR
>Mature_413_residues
MIPLEEFRAEAEAFLAASGLPRRDEDETIVWGEGELDVSVFHNLTFEEESALLGELKDWQRRKLEAGFGAITWEPEYGGR
GLGAEHLDAFDELEARYETPRPHETFSVTQHLIAPTVRLFGTEAMRTELIPAFLRGERICCQLFSEPSAGSDLAALGTRA
VREGDEWVINGQKVWSSGAQFADWGELICRSDPTQPKHAGMTAFMIPMDWPGVEVRPLRQMSGGSSFSEVFLTDVRLPDS
HRIGDIGEGWKVALTTLGFERQAANNNAHVGGNWRQLLATAQWADVLDDPFVRQDLAKAVISERLGAVAVARDQAARESG
EPMGAIGSIRMMQWVGRMLDVTAAARRILGPRLVVDHGDWGTYVWGEHVLGAPGYRIAGGSDEIQRTIIAERWLGMPAEP
RADKDTPWKDLPR

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=234, Percent_Identity=30.7692307692308, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI7656849, Length=357, Percent_Identity=24.6498599439776, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI4557233, Length=158, Percent_Identity=32.9113924050633, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4557231, Length=266, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI187960098, Length=266, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI76496475, Length=351, Percent_Identity=25.9259259259259, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4557235, Length=351, Percent_Identity=25.9259259259259, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI226958412, Length=215, Percent_Identity=27.906976744186, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI226958414, Length=203, Percent_Identity=29.064039408867, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI21361497, Length=240, Percent_Identity=26.25, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4501857, Length=159, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=354, Percent_Identity=25.7062146892655, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=223, Percent_Identity=30.9417040358744, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=269, Percent_Identity=28.2527881040892, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=303, Percent_Identity=27.7227722772277, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=199, Percent_Identity=28.1407035175879, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=191, Percent_Identity=29.3193717277487, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17533517, Length=356, Percent_Identity=24.7191011235955, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=234, Percent_Identity=29.0598290598291, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=211, Percent_Identity=25.5924170616114, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=204, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=203, Percent_Identity=29.064039408867, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=204, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=191, Percent_Identity=29.8429319371728, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=189, Percent_Identity=27.5132275132275, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646207, Length=202, Percent_Identity=32.6732673267327, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356377, Length=203, Percent_Identity=31.5270935960591, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21355753, Length=208, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24660351, Length=291, Percent_Identity=27.8350515463918, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI281363737, Length=153, Percent_Identity=28.7581699346405, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 45785; Mature: 45785

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPLEEFRAEAEAFLAASGLPRRDEDETIVWGEGELDVSVFHNLTFEEESALLGELKDWQ
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEHHHCCCCCHHHHHHHHHHHHH
RRKLEAGFGAITWEPEYGGRGLGAEHLDAFDELEARYETPRPHETFSVTQHLIAPTVRLF
HHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
GTEAMRTELIPAFLRGERICCQLFSEPSAGSDLAALGTRAVREGDEWVINGQKVWSSGAQ
CCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHCCCCC
FADWGELICRSDPTQPKHAGMTAFMIPMDWPGVEVRPLRQMSGGSSFSEVFLTDVRLPDS
CCHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHHEEECCCCCC
HRIGDIGEGWKVALTTLGFERQAANNNAHVGGNWRQLLATAQWADVLDDPFVRQDLAKAV
CCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ISERLGAVAVARDQAARESGEPMGAIGSIRMMQWVGRMLDVTAAARRILGPRLVVDHGDW
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GTYVWGEHVLGAPGYRIAGGSDEIQRTIIAERWLGMPAEPRADKDTPWKDLPR
CCEECCCHHCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIPLEEFRAEAEAFLAASGLPRRDEDETIVWGEGELDVSVFHNLTFEEESALLGELKDWQ
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEHHHCCCCCHHHHHHHHHHHHH
RRKLEAGFGAITWEPEYGGRGLGAEHLDAFDELEARYETPRPHETFSVTQHLIAPTVRLF
HHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
GTEAMRTELIPAFLRGERICCQLFSEPSAGSDLAALGTRAVREGDEWVINGQKVWSSGAQ
CCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHCCCCC
FADWGELICRSDPTQPKHAGMTAFMIPMDWPGVEVRPLRQMSGGSSFSEVFLTDVRLPDS
CCHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHHEEECCCCCC
HRIGDIGEGWKVALTTLGFERQAANNNAHVGGNWRQLLATAQWADVLDDPFVRQDLAKAV
CCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ISERLGAVAVARDQAARESGEPMGAIGSIRMMQWVGRMLDVTAAARRILGPRLVVDHGDW
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GTYVWGEHVLGAPGYRIAGGSDEIQRTIIAERWLGMPAEPRADKDTPWKDLPR
CCEECCCHHCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]