| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is livF [H]
Identifier: 119718331
GI number: 119718331
Start: 4343247
End: 4343972
Strand: Reverse
Name: livF [H]
Synonym: Noca_4112
Alternate gene names: 119718331
Gene position: 4343972-4343247 (Counterclockwise)
Preceding gene: 119718332
Following gene: 119718329
Centisome position: 87.13
GC content: 73.28
Gene sequence:
>726_bases ATGACCGCTGACACAGCCGCAGTCGAGCGGCGGACGTCCGCAGCACTCGCCGTGCGCGACCTCGCCGTGCGGTACGGCCG CGCGGTCGCCGTCGAGCACATCTCCCTCACGGTCGGCACCGGGGAGTGCCTGGCCGTGGTCGGTGCCAACGGCGCCGGGA AGAGCACCCTGGGCAAGGCCGTGTCCGGCCTGGTCCCGCTGGCCGGCGGGGCCGTCGAGTACGGCGGTCGACCGGTCGGC CGCGACGCCGTGCGCGCCGGGATCGTCTACGTGCCCGAGGGCCGGATGGTCTTCCCGCAGCTCACCGTCGAGGAGAACCT CAAGGTGGGCGGGTTCGTCCGCCGGCGCCGGGACGACTGGCGAGAGCAGCGTGACGCGATGTATGCGCTGGTGCCCCGGC TGGCGGACCGGTCCTCCCTCCGTGCCGGGCTGCTGAGCGGCGGTGAGCAGCAGCTGCTCGCGATCGCCCGTGCGTTGATG GCCCGGCCGCGGCTGCTGGTCCTCGACGAGCCGTCGCTCGGGCTCTCGCCGATGGCGATCGGGACCGTCACCCGGTTCCT CGACGAGCTGCGCGCGGAGACCGACCTGAGCATCCTGCTCCTCGAGCAGAACACCGCCTTCGCCGCCCGCCTGGCCGATC GGGGCATGGTCGCGAAGCTCGGCCGGATCGACCGGGACGACCTGAGCCAGGCCGACCTCGCCGAGATCTCGGTCTTCCAG GGCTGA
Upstream 100 bases:
>100_bases TCGTCGACCGGCTCGTCGTCCTCGACGCCGGTCGCAAGATCGCCGAGGCCACCCCGGAGGAGCTCGCGGCGCGCCCCGAC CTCGTGGAGGACTACCTGAC
Downstream 100 bases:
>100_bases GGTCGCCCGCCGGGCCCGAGGGTCGGCCGGCCCGGCGGGCCGGGGTCCGACTCAGTCCTGGTCCATCCGGAGCGCGTTGG CCCAGAGCCGGGTGAGGCTG
Product: ABC transporter-like protein
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 241; Mature: 240
Protein sequence:
>241_residues MTADTAAVERRTSAALAVRDLAVRYGRAVAVEHISLTVGTGECLAVVGANGAGKSTLGKAVSGLVPLAGGAVEYGGRPVG RDAVRAGIVYVPEGRMVFPQLTVEENLKVGGFVRRRRDDWREQRDAMYALVPRLADRSSLRAGLLSGGEQQLLAIARALM ARPRLLVLDEPSLGLSPMAIGTVTRFLDELRAETDLSILLLEQNTAFAARLADRGMVAKLGRIDRDDLSQADLAEISVFQ G
Sequences:
>Translated_241_residues MTADTAAVERRTSAALAVRDLAVRYGRAVAVEHISLTVGTGECLAVVGANGAGKSTLGKAVSGLVPLAGGAVEYGGRPVG RDAVRAGIVYVPEGRMVFPQLTVEENLKVGGFVRRRRDDWREQRDAMYALVPRLADRSSLRAGLLSGGEQQLLAIARALM ARPRLLVLDEPSLGLSPMAIGTVTRFLDELRAETDLSILLLEQNTAFAARLADRGMVAKLGRIDRDDLSQADLAEISVFQ G >Mature_240_residues TADTAAVERRTSAALAVRDLAVRYGRAVAVEHISLTVGTGECLAVVGANGAGKSTLGKAVSGLVPLAGGAVEYGGRPVGR DAVRAGIVYVPEGRMVFPQLTVEENLKVGGFVRRRRDDWREQRDAMYALVPRLADRSSLRAGLLSGGEQQLLAIARALMA RPRLLVLDEPSLGLSPMAIGTVTRFLDELRAETDLSILLLEQNTAFAARLADRGMVAKLGRIDRDDLSQADLAEISVFQG
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI45446740, Length=203, Percent_Identity=33.0049261083744, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI47078218, Length=203, Percent_Identity=33.0049261083744, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI27436953, Length=199, Percent_Identity=29.6482412060301, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI153792144, Length=217, Percent_Identity=30.4147465437788, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI105990541, Length=198, Percent_Identity=28.7878787878788, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI27477115, Length=207, Percent_Identity=29.951690821256, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI46592978, Length=230, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI46592964, Length=231, Percent_Identity=28.1385281385281, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI46592956, Length=230, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI46592898, Length=231, Percent_Identity=28.1385281385281, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI46592915, Length=231, Percent_Identity=28.1385281385281, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI46592971, Length=230, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI27881501, Length=210, Percent_Identity=27.1428571428571, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI30795238, Length=210, Percent_Identity=27.1428571428571, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI11967969, Length=229, Percent_Identity=25.764192139738, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI6005701, Length=201, Percent_Identity=30.3482587064677, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI116734710, Length=188, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI21536376, Length=206, Percent_Identity=27.1844660194175, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI11967971, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI31657092, Length=206, Percent_Identity=27.1844660194175, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI255708477, Length=168, Percent_Identity=30.952380952381, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI27262624, Length=200, Percent_Identity=29.5, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI27262626, Length=200, Percent_Identity=29.5, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI148612844, Length=168, Percent_Identity=30.952380952381, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI42741659, Length=219, Percent_Identity=28.7671232876712, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI87082268, Length=227, Percent_Identity=42.2907488986784, Blast_Score=167, Evalue=5e-43, Organism=Escherichia coli, GI1787029, Length=220, Percent_Identity=29.0909090909091, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1789593, Length=219, Percent_Identity=32.8767123287671, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1787792, Length=243, Percent_Identity=31.2757201646091, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789864, Length=226, Percent_Identity=29.2035398230088, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI1788761, Length=220, Percent_Identity=29.5454545454545, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI1789672, Length=219, Percent_Identity=28.7671232876712, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI48994943, Length=211, Percent_Identity=28.9099526066351, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1790162, Length=234, Percent_Identity=28.6324786324786, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1786563, Length=201, Percent_Identity=31.8407960199005, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787500, Length=213, Percent_Identity=30.9859154929577, Blast_Score=85, Evalue=3e-18, Organism=Escherichia coli, GI1788225, Length=223, Percent_Identity=28.6995515695067, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1790525, Length=208, Percent_Identity=29.8076923076923, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI1790190, Length=208, Percent_Identity=31.25, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1787089, Length=216, Percent_Identity=31.4814814814815, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI87081834, Length=210, Percent_Identity=29.0476190476191, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1788165, Length=203, Percent_Identity=32.0197044334975, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1786872, Length=220, Percent_Identity=30.4545454545455, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1790544, Length=232, Percent_Identity=28.0172413793103, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI87081782, Length=166, Percent_Identity=33.7349397590361, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787712, Length=219, Percent_Identity=27.3972602739726, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789991, Length=173, Percent_Identity=31.2138728323699, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI87081709, Length=214, Percent_Identity=27.1028037383178, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI87081791, Length=168, Percent_Identity=30.952380952381, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1788897, Length=219, Percent_Identity=29.2237442922374, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1787370, Length=209, Percent_Identity=27.7511961722488, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1789962, Length=204, Percent_Identity=28.4313725490196, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI48994883, Length=250, Percent_Identity=26, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1790467, Length=212, Percent_Identity=27.8301886792453, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789891, Length=212, Percent_Identity=29.7169811320755, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1786703, Length=192, Percent_Identity=32.2916666666667, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1788450, Length=206, Percent_Identity=27.6699029126214, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI48995001, Length=250, Percent_Identity=26.8, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1787164, Length=203, Percent_Identity=29.064039408867, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1786319, Length=168, Percent_Identity=35.1190476190476, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1787547, Length=226, Percent_Identity=25.6637168141593, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1788210, Length=255, Percent_Identity=28.2352941176471, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1788506, Length=239, Percent_Identity=28.0334728033473, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI48994997, Length=229, Percent_Identity=28.3842794759825, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787758, Length=202, Percent_Identity=29.2079207920792, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1789963, Length=232, Percent_Identity=28.448275862069, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI145693107, Length=247, Percent_Identity=28.7449392712551, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1786398, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1786253, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787105, Length=206, Percent_Identity=31.0679611650485, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI1786803, Length=221, Percent_Identity=27.6018099547511, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1786654, Length=184, Percent_Identity=28.2608695652174, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1788644, Length=237, Percent_Identity=26.1603375527426, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI87082267, Length=197, Percent_Identity=27.9187817258883, Blast_Score=62, Evalue=4e-11, Organism=Escherichia coli, GI1788472, Length=173, Percent_Identity=26.5895953757225, Blast_Score=60, Evalue=1e-10, Organism=Caenorhabditis elegans, GI71983523, Length=197, Percent_Identity=30.4568527918782, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71983516, Length=197, Percent_Identity=30.4568527918782, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71983510, Length=197, Percent_Identity=30.4568527918782, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI115533608, Length=232, Percent_Identity=29.3103448275862, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17510237, Length=226, Percent_Identity=25.6637168141593, Blast_Score=77, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17565586, Length=203, Percent_Identity=27.0935960591133, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71992285, Length=191, Percent_Identity=27.7486910994764, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI25146777, Length=198, Percent_Identity=29.2929292929293, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI115532730, Length=187, Percent_Identity=32.0855614973262, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI71988343, Length=177, Percent_Identity=30.5084745762712, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI28574150, Length=181, Percent_Identity=28.7292817679558, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI116007328, Length=181, Percent_Identity=28.7292817679558, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24666092, Length=213, Percent_Identity=28.6384976525822, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI24643674, Length=167, Percent_Identity=26.3473053892216, Blast_Score=74, Evalue=6e-14, Organism=Drosophila melanogaster, GI24650853, Length=177, Percent_Identity=29.9435028248588, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI28573573, Length=194, Percent_Identity=28.8659793814433, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI28573571, Length=194, Percent_Identity=28.8659793814433, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24650855, Length=177, Percent_Identity=29.9435028248588, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24582014, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24582012, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI221512771, Length=212, Percent_Identity=27.8301886792453, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI28574744, Length=181, Percent_Identity=29.2817679558011, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI17136592, Length=197, Percent_Identity=29.9492385786802, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI19920532, Length=186, Percent_Identity=27.9569892473118, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24580930, Length=186, Percent_Identity=27.9569892473118, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281362751, Length=177, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28574533, Length=188, Percent_Identity=29.7872340425532, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24648314, Length=211, Percent_Identity=25.5924170616114, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI116007184, Length=230, Percent_Identity=26.9565217391304, Blast_Score=64, Evalue=8e-11, Organism=Drosophila melanogaster, GI24641565, Length=207, Percent_Identity=27.536231884058, Blast_Score=64, Evalue=9e-11, Organism=Drosophila melanogaster, GI221500365, Length=226, Percent_Identity=26.9911504424779, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 25693; Mature: 25562
Theoretical pI: Translated: 9.09; Mature: 9.09
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTADTAAVERRTSAALAVRDLAVRYGRAVAVEHISLTVGTGECLAVVGANGAGKSTLGKA CCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCEEEEEECCCCCHHHHHHH VSGLVPLAGGAVEYGGRPVGRDAVRAGIVYVPEGRMVFPQLTVEENLKVGGFVRRRRDDW HHCCCCCCCCCHHCCCCCCCCHHHHCCEEECCCCCEECCEECCCCCCCCCHHHHHHHHHH REQRDAMYALVPRLADRSSLRAGLLSGGEQQLLAIARALMARPRLLVLDEPSLGLSPMAI HHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH GTVTRFLDELRAETDLSILLLEQNTAFAARLADRGMVAKLGRIDRDDLSQADLAEISVFQ HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCHHHHHCCCCHHHCCCCCHHHHEECC G C >Mature Secondary Structure TADTAAVERRTSAALAVRDLAVRYGRAVAVEHISLTVGTGECLAVVGANGAGKSTLGKA CCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCEEEEEECCCCCHHHHHHH VSGLVPLAGGAVEYGGRPVGRDAVRAGIVYVPEGRMVFPQLTVEENLKVGGFVRRRRDDW HHCCCCCCCCCHHCCCCCCCCHHHHCCEEECCCCCEECCEECCCCCCCCCHHHHHHHHHH REQRDAMYALVPRLADRSSLRAGLLSGGEQQLLAIARALMARPRLLVLDEPSLGLSPMAI HHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH GTVTRFLDELRAETDLSILLLEQNTAFAARLADRGMVAKLGRIDRDDLSQADLAEISVFQ HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCHHHHHCCCCHHHCCCCCHHHHEECC G C
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]