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The map label for this gene is kipR [H]

Identifier: 119718314

GI number: 119718314

Start: 4326187

End: 4326996

Strand: Reverse

Name: kipR [H]

Synonym: Noca_4095

Alternate gene names: 119718314

Gene position: 4326996-4326187 (Counterclockwise)

Preceding gene: 119718317

Following gene: 119718313

Centisome position: 86.79

GC content: 69.26

Gene sequence:

>810_bases
ATGTCCCCCAGGTCCCGATCCACCCTTGTCGACGGAGCGGAGAGCGGGAGCGCCACGATCGCCACGGTCGAGCGCGCGGC
CGACATCTTGATGCACTTCGCCTCGACGCCTCAAACCGACTTCGGCGTGACCGAGATCGCCGAGGAGCTCGGTCTCTCCA
AGGCCGCCGTGCACCGGGTGCTGGCCTCGCTGCGCAGCCGTGGGCTCGTTGAGCTCGACGAGCGAACCCGCCGGTACTCG
CTGGGCGTCTCGGCGATGAAGCTCGGGCTGACCTATCTCGAGCGCATCGACGTCCGGAGGGTGGGTCGCCCCTACCTGCA
GGAGCTCACTGCGCGCACCGACGAGACGGCGACGCTCTCGGTGCGGGTGGGTGACCGCTCCCGGGTCTACGTCGACCAGA
TCACCCCCGAGCGTGAGGTGATCATGGCCGTCACTCTCGGTGAGCCGTATCCGCTGCACGCCGGCGCGTCGTCGCGAGCC
CTCCTGGCGTTCTTGCCGGAGGACAAGATCGAGGCGTACATCTCCTCCGGCCCGCTGCAGTCGATGACCGCTTCCACCAT
CATCGATCCGGGCATGCTGCGCGAGGATCTGGCCGCGGTCCGAGAGCAGGGCTGGGCCCGGTCATCCGCCGAGCGGAAGA
ACGGCGCGGCCTCTGTCGCCGCACCCGTTCGAGGACACGACGGCTACGCCGTGGCCGTGGTCAGCGTGTGTGGGCCGCTC
GAGCGCTTCTCCGCGGAGTTCGAGGGCTGCCGTGACGCGCTGCTGCACGCCACCCGAACGCTGTCGCGTCAGTTCGGGTT
CGACGGGTAG

Upstream 100 bases:

>100_bases
CGGCGACTAACATCGTCCCGGGTCGTCCGCCGCAGGCGGAATCGGGTCACCGATGTCGCGACGCCGCCGTTCGATGAAGG
CGACTCAGAGGAAGTGAGCA

Downstream 100 bases:

>100_bases
CGACCGGGGTCGCCGCACCGGGCGCGGTCGCCGGGGTGGCAACCGCGCCGAACGGCCGCTGACCTGCGCCTCGTCACGGG
GTGCAGGTGCTCACCGTGCG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSPRSRSTLVDGAESGSATIATVERAADILMHFASTPQTDFGVTEIAEELGLSKAAVHRVLASLRSRGLVELDERTRRYS
LGVSAMKLGLTYLERIDVRRVGRPYLQELTARTDETATLSVRVGDRSRVYVDQITPEREVIMAVTLGEPYPLHAGASSRA
LLAFLPEDKIEAYISSGPLQSMTASTIIDPGMLREDLAAVREQGWARSSAERKNGAASVAAPVRGHDGYAVAVVSVCGPL
ERFSAEFEGCRDALLHATRTLSRQFGFDG

Sequences:

>Translated_269_residues
MSPRSRSTLVDGAESGSATIATVERAADILMHFASTPQTDFGVTEIAEELGLSKAAVHRVLASLRSRGLVELDERTRRYS
LGVSAMKLGLTYLERIDVRRVGRPYLQELTARTDETATLSVRVGDRSRVYVDQITPEREVIMAVTLGEPYPLHAGASSRA
LLAFLPEDKIEAYISSGPLQSMTASTIIDPGMLREDLAAVREQGWARSSAERKNGAASVAAPVRGHDGYAVAVVSVCGPL
ERFSAEFEGCRDALLHATRTLSRQFGFDG
>Mature_268_residues
SPRSRSTLVDGAESGSATIATVERAADILMHFASTPQTDFGVTEIAEELGLSKAAVHRVLASLRSRGLVELDERTRRYSL
GVSAMKLGLTYLERIDVRRVGRPYLQELTARTDETATLSVRVGDRSRVYVDQITPEREVIMAVTLGEPYPLHAGASSRAL
LAFLPEDKIEAYISSGPLQSMTASTIIDPGMLREDLAAVREQGWARSSAERKNGAASVAAPVRGHDGYAVAVVSVCGPLE
RFSAEFEGCRDALLHATRTLSRQFGFDG

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=249, Percent_Identity=31.7269076305221, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788131, Length=229, Percent_Identity=29.6943231441048, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082359, Length=216, Percent_Identity=25, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786715, Length=235, Percent_Identity=28.0851063829787, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788581, Length=255, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1789999, Length=197, Percent_Identity=27.4111675126904, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790752, Length=200, Percent_Identity=25.5, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29124; Mature: 28993

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRSRSTLVDGAESGSATIATVERAADILMHFASTPQTDFGVTEIAEELGLSKAAVHRV
CCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHH
LASLRSRGLVELDERTRRYSLGVSAMKLGLTYLERIDVRRVGRPYLQELTARTDETATLS
HHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEE
VRVGDRSRVYVDQITPEREVIMAVTLGEPYPLHAGASSRALLAFLPEDKIEAYISSGPLQ
EEECCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCHH
SMTASTIIDPGMLREDLAAVREQGWARSSAERKNGAASVAAPVRGHDGYAVAVVSVCGPL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCEEECCCCCCCCCEEHHHHHHCCH
ERFSAEFEGCRDALLHATRTLSRQFGFDG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SPRSRSTLVDGAESGSATIATVERAADILMHFASTPQTDFGVTEIAEELGLSKAAVHRV
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHH
LASLRSRGLVELDERTRRYSLGVSAMKLGLTYLERIDVRRVGRPYLQELTARTDETATLS
HHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEE
VRVGDRSRVYVDQITPEREVIMAVTLGEPYPLHAGASSRALLAFLPEDKIEAYISSGPLQ
EEECCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCHH
SMTASTIIDPGMLREDLAAVREQGWARSSAERKNGAASVAAPVRGHDGYAVAVVSVCGPL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCEEECCCCCCCCCEEHHHHHHCCH
ERFSAEFEGCRDALLHATRTLSRQFGFDG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]