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The map label for this gene is fadE25 [H]

Identifier: 119718281

GI number: 119718281

Start: 4288713

End: 4289882

Strand: Reverse

Name: fadE25 [H]

Synonym: Noca_4062

Alternate gene names: 119718281

Gene position: 4289882-4288713 (Counterclockwise)

Preceding gene: 119718282

Following gene: 119718278

Centisome position: 86.04

GC content: 70.09

Gene sequence:

>1170_bases
GTGTCCGAGTTCCCTTTGTTCGCGCTGTCTGAGGAGCACCAGGCCGTCCGCGAGGCGGCCCGAGCCGTGTGCGACGCGAA
GGTCGCACCGTTCGCCGCCGACGTCGACGAGCACGCCCGCTACCCGCGGGAGGCGGCCGAGGCCTTGTTGGCCGCCGACT
TCCACGCCCCGCACATCCCGGAGCAGTACGGCGGTGCCGGCGCCGACGCGCTCGCCACCGTGATCATCATCGAGGGGGTC
GCCCGGGCGTGTGCCTCGAGCAGCCTGATCCCGGCGGTGAACAAGCTGGGGTCGCTGCCGATCCAGTTGGCCGGCTCGGA
GGAGCTGAAGGCGAAGTACCTGGGTGCGCTGGCGCGCGGTGAGGGCGGGTTCTCCTACTGCCTCTCCGAGCCGGACGCGG
GCTCGGACGCGGTGGGGATGAAGGCCCGAGCCGTGCGCGACGGGGACACCTGGGTGCTCAACGGCGTCAAGCGCTGGATC
ACCAACGCGGGCGAGTCGGAGTACTACACGGTGATGGCGGTGACGGACCCCGAGAAGCGCTCCCGGGGGATCAGCGCGTT
CGTGGTGGAGAAGAGCGACGAGGGTGTCTCCTTCGGTGCCCCGGAGAAGAAGCTCGGCATCAAGGGCTCTCCGACCCGGG
AGGTCTACCTGGACAACGTCCGCATCGGTGCGGACCGGATGATCGGGGCGGAGGGCGCCGGGTTCGAGATCGCGATGCGC
ACCCTGGACCACACCCGGGTCACGATCGCGGCGCAGGCCGTCGGCATCGCCCAGGGGGCGTTGGACTACGCGCTGGGCTA
CGCCCAGGAGCGCAAGCAGTTCGGGAAGCCGATCAGCGACTTCCAGGGGCTGCAGTTCCTGCTGGCCGACATGGGGATGA
AGGTCGAGGCGGCGCGGCAGCTGACCTACGCGGCGGCCGGGAAGTCCGAGCGGGGCGACAGCGACCTGACGTTCTTCGGG
GCCGCGGCGAAGTGCTTCGCCTCCGACGTCGCCATGGAGGTCACCACCAACGCCGTCCAGGTCCTCGGCGGGTACGGCTA
CACCCGGGACTACCCGGTCGAGCGGATGATGCGGGACGCGAAGATCACCCAGATCTACGAGGGCACCAACCAGGTCCAGC
GGATCGTGATGGCCCGCCAGCTCCTCGCCGGGGTGCAGAGCCGCCTCTGA

Upstream 100 bases:

>100_bases
TGCGCGCGCACCTGCGGCGTCTGCGCGACATCTACCTGGCCTGACCGGACGCTCGACCAAGCATCGTCCGCCGTCACCGA
TCACTCGAAGGAGCGAGCCC

Downstream 100 bases:

>100_bases
CCCGGACGTTCGACGAACCGTGTGAGATCGGGTCAGGGCGCCAGACGACTGCCCCGTGCCGGTCGGGCGTGAGACGGCTT
AGCCCGGATGTGTGAACGCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHIPEQYGGAGADALATVIIIEGV
ARACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALARGEGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRWI
TNAGESEYYTVMAVTDPEKRSRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGAGFEIAMR
TLDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAARQLTYAAAGKSERGDSDLTFFG
AAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRDAKITQIYEGTNQVQRIVMARQLLAGVQSRL

Sequences:

>Translated_389_residues
MSEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHIPEQYGGAGADALATVIIIEGV
ARACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALARGEGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRWI
TNAGESEYYTVMAVTDPEKRSRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGAGFEIAMR
TLDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAARQLTYAAAGKSERGDSDLTFFG
AAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRDAKITQIYEGTNQVQRIVMARQLLAGVQSRL
>Mature_388_residues
SEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHIPEQYGGAGADALATVIIIEGVA
RACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALARGEGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRWIT
NAGESEYYTVMAVTDPEKRSRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGAGFEIAMRT
LDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAARQLTYAAAGKSERGDSDLTFFGA
AAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRDAKITQIYEGTNQVQRIVMARQLLAGVQSRL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=38.9920424403183, Blast_Score=288, Evalue=6e-78,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=38.9920424403183, Blast_Score=288, Evalue=7e-78,
Organism=Homo sapiens, GI4557233, Length=382, Percent_Identity=42.4083769633508, Blast_Score=287, Evalue=9e-78,
Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=37.8306878306878, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=36.2433862433862, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI21361497, Length=359, Percent_Identity=37.6044568245125, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=34.3832020997375, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI76496475, Length=331, Percent_Identity=36.2537764350453, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI4557235, Length=331, Percent_Identity=36.2537764350453, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI226958414, Length=328, Percent_Identity=36.280487804878, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=29.6296296296296, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI4503943, Length=387, Percent_Identity=27.1317829457364, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI7669494, Length=367, Percent_Identity=27.2479564032698, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI38505218, Length=298, Percent_Identity=27.8523489932886, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI211971008, Length=286, Percent_Identity=29.7202797202797, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI48976061, Length=286, Percent_Identity=29.7202797202797, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI87081958, Length=385, Percent_Identity=30.9090909090909, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=27.7044854881267, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI87082384, Length=265, Percent_Identity=25.2830188679245, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081702, Length=410, Percent_Identity=25.1219512195122, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=40.8970976253298, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=40.3141361256544, Blast_Score=294, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=40.2631578947368, Blast_Score=292, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17506239, Length=378, Percent_Identity=37.037037037037, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17508101, Length=379, Percent_Identity=39.0501319261214, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17533517, Length=380, Percent_Identity=34.4736842105263, Blast_Score=237, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=36.4116094986807, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71990804, Length=273, Percent_Identity=39.9267399267399, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71985184, Length=360, Percent_Identity=35.2777777777778, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI32563615, Length=239, Percent_Identity=39.7489539748954, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71982178, Length=279, Percent_Identity=34.7670250896057, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=30.6666666666667, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17551932, Length=383, Percent_Identity=29.7650130548303, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=286, Percent_Identity=34.6153846153846, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17531909, Length=252, Percent_Identity=30.5555555555556, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17534353, Length=379, Percent_Identity=26.6490765171504, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17562446, Length=349, Percent_Identity=28.9398280802292, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI86563381, Length=273, Percent_Identity=30.4029304029304, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=273, Percent_Identity=30.4029304029304, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=40.4761904761905, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=41.2698412698413, Blast_Score=274, Evalue=9e-74,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=40.053050397878, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=35.5437665782493, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=36.2924281984334, Blast_Score=214, Evalue=5e-56,
Organism=Drosophila melanogaster, GI281363737, Length=388, Percent_Identity=33.2474226804124, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=27.5132275132275, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41607; Mature: 41475

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHIP
CCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCC
EQYGGAGADALATVIIIEGVARACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALARG
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHCC
EGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRWITNAGESEYYTVMAVTDPEKR
CCCCEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEECHHHH
SRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGAGFEIAMR
HCCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCEEEECCEEECCHHEECCCCCCHHHHEE
TLDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAARQ
HHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
LTYAAAGKSERGDSDLTFFGAAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRDA
HHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KITQIYEGTNQVQRIVMARQLLAGVQSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEFPLFALSEEHQAVREAARAVCDAKVAPFAADVDEHARYPREAAEALLAADFHAPHIP
CCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCC
EQYGGAGADALATVIIIEGVARACASSSLIPAVNKLGSLPIQLAGSEELKAKYLGALARG
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHCC
EGGFSYCLSEPDAGSDAVGMKARAVRDGDTWVLNGVKRWITNAGESEYYTVMAVTDPEKR
CCCCEEECCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEECHHHH
SRGISAFVVEKSDEGVSFGAPEKKLGIKGSPTREVYLDNVRIGADRMIGAEGAGFEIAMR
HCCCEEEEEECCCCCCCCCCCCHHCCCCCCCCCEEEECCEEECCHHEECCCCCCHHHHEE
TLDHTRVTIAAQAVGIAQGALDYALGYAQERKQFGKPISDFQGLQFLLADMGMKVEAARQ
HHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
LTYAAAGKSERGDSDLTFFGAAAKCFASDVAMEVTTNAVQVLGGYGYTRDYPVERMMRDA
HHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KITQIYEGTNQVQRIVMARQLLAGVQSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]