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The map label for this gene is proY [C]

Identifier: 119718256

GI number: 119718256

Start: 4260860

End: 4262320

Strand: Reverse

Name: proY [C]

Synonym: Noca_4037

Alternate gene names: 119718256

Gene position: 4262320-4260860 (Counterclockwise)

Preceding gene: 119718258

Following gene: 119718255

Centisome position: 85.49

GC content: 66.26

Gene sequence:

>1461_bases
ATGAGCGAACAAGCCCCGAGACGTATCCACGAGCGGGGTGGGATCGATGCTTCCGTCGAAGGAACCGAGTACTTCGAGAA
GCGTCAGCTCGCAGGTGGGGTGGCCGGCTGGCTGCTCCTGGCGGGGCTGGGTGTTGCCTACGTCATCTCCGGAGACTTCG
CAGGCTGGAACTTCGGCATGGGCGAAGGCGGCTGGGGCGGGATGCTGATCGCCACCGGCCTGATGGGGACGATGTACCTG
TTCATGGTCCTGGGGCTCGCGGAGCTCTCCTCGACCATCTCGACGACCGGGGGCGGCTACGCGTTCGCCCGCCGGGCCAT
GGGGCCGTGGGGCGGGTTCCTCACCGGCACCGCGATTCTCATCGAGTACGCCATCGCGCCCGCGGCGATCGCGAACTTCA
TCGGCGCCTACGTCGAGTCGCTGACCGGCTTCGACGTCGGCTGGGTCGTCTTCCTGGTCTTCTACGCCGTCTTCATCGGC
CTCCACCTGTGGGGCGTCGGTGAGGCGTTGAAGCTCATGTTCGTGATCACCGCGATCGCGGTCGTCGCCCTGTTCGTCTT
CGTGATCGCAGCGCTGCCGAAGTTCGACGCCTCGAACCTCAACAGCATCCCGGTGGACACCTCGGCGTTCGGGTCGAGCT
CGTTCCTGCCGTTCGGTCTGGTCGGCATCTGGGCCGCACTGCCCTACGCCATCTGGTTCTACCTGGCCGTCGAGGGCGTG
CCGCTGGCTGCTGAGGAGTCCAAGGATCCGGCCAAGGACATGCCGCGCGGCATCATCGCCGCCATCGTGACGCTGCTCGT
CTTCGCGTTCGTCATCCTCCTGGTGGCGCCGGGCGCGGCCGGCTCGGACTTCCTGAAGGACTCGGGCAACCCGCTGGTCG
AGGCCCTCGAGGCCCCCGGCGCCTATGGCGGCCAGAACCTGGTCAGTCAGTTCATCAACCTGGTCGGCCTCCTCGGCCTG
ATCGCGAGCTTCTTCTCGATCATCTTCGCCTACTCCCGCCAGACGTTCGCGCTGTCGCGTGCCGGTTATCTGCCGAAGTT
CCTTTCGCTCACCGGCCAGAGGAAGACGCCGTACGTCGCCCTGATCGTCCCGGGCATCATCGGCTTCGTCATGGCCGTGC
TCAACCAGGGCGACCTGCTCATCCTGGTGGCGGTCTTCGGCGCCACGATCTCGTACGTCATGATGACGCTCTCGCACATC
ATCTTGCGGTTCAAGGAGCCCGAGCTCGACCGGCCCTACCGCACGCCCGGTGGCGTCGTCACGACCGGCATCGCCTGTGT
GCTGGGCGTGGTGGCCCTCATCGCAGGGTTCCTCGTGGACACCCGCGTGGTCGCCATCACCGCCGGCGTCTACGTGATCG
CCATCGCCTACTTCGGCCTCTACAGCCGACACCACATCGTGGCGTCGGCTCCCGAGGAGGAGTTCGCCCTGATCGAGTCC
TCCGAGTCCGAGCTGCACTGA

Upstream 100 bases:

>100_bases
GCCCGAACTCGTTGCTCGAGGACGGTTGAAATGTTTAGCGTCACCCCGCGGCTCTCGGGCCGCTCTAGAGCCACATTGGC
GCGACCTAAGGACGGTCCGA

Downstream 100 bases:

>100_bases
CATGCGCATCGCACGAGTGGTTGGCTCGGCGGTCTCGACCGTCAAGGACCCGAGCCTGGTCGGGCACAAGCTCCTCCTGG
TCCAGGAGACGGACGCAAGC

Product: ethanolamine transporter

Products: Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MSEQAPRRIHERGGIDASVEGTEYFEKRQLAGGVAGWLLLAGLGVAYVISGDFAGWNFGMGEGGWGGMLIATGLMGTMYL
FMVLGLAELSSTISTTGGGYAFARRAMGPWGGFLTGTAILIEYAIAPAAIANFIGAYVESLTGFDVGWVVFLVFYAVFIG
LHLWGVGEALKLMFVITAIAVVALFVFVIAALPKFDASNLNSIPVDTSAFGSSSFLPFGLVGIWAALPYAIWFYLAVEGV
PLAAEESKDPAKDMPRGIIAAIVTLLVFAFVILLVAPGAAGSDFLKDSGNPLVEALEAPGAYGGQNLVSQFINLVGLLGL
IASFFSIIFAYSRQTFALSRAGYLPKFLSLTGQRKTPYVALIVPGIIGFVMAVLNQGDLLILVAVFGATISYVMMTLSHI
ILRFKEPELDRPYRTPGGVVTTGIACVLGVVALIAGFLVDTRVVAITAGVYVIAIAYFGLYSRHHIVASAPEEEFALIES
SESELH

Sequences:

>Translated_486_residues
MSEQAPRRIHERGGIDASVEGTEYFEKRQLAGGVAGWLLLAGLGVAYVISGDFAGWNFGMGEGGWGGMLIATGLMGTMYL
FMVLGLAELSSTISTTGGGYAFARRAMGPWGGFLTGTAILIEYAIAPAAIANFIGAYVESLTGFDVGWVVFLVFYAVFIG
LHLWGVGEALKLMFVITAIAVVALFVFVIAALPKFDASNLNSIPVDTSAFGSSSFLPFGLVGIWAALPYAIWFYLAVEGV
PLAAEESKDPAKDMPRGIIAAIVTLLVFAFVILLVAPGAAGSDFLKDSGNPLVEALEAPGAYGGQNLVSQFINLVGLLGL
IASFFSIIFAYSRQTFALSRAGYLPKFLSLTGQRKTPYVALIVPGIIGFVMAVLNQGDLLILVAVFGATISYVMMTLSHI
ILRFKEPELDRPYRTPGGVVTTGIACVLGVVALIAGFLVDTRVVAITAGVYVIAIAYFGLYSRHHIVASAPEEEFALIES
SESELH
>Mature_485_residues
SEQAPRRIHERGGIDASVEGTEYFEKRQLAGGVAGWLLLAGLGVAYVISGDFAGWNFGMGEGGWGGMLIATGLMGTMYLF
MVLGLAELSSTISTTGGGYAFARRAMGPWGGFLTGTAILIEYAIAPAAIANFIGAYVESLTGFDVGWVVFLVFYAVFIGL
HLWGVGEALKLMFVITAIAVVALFVFVIAALPKFDASNLNSIPVDTSAFGSSSFLPFGLVGIWAALPYAIWFYLAVEGVP
LAAEESKDPAKDMPRGIIAAIVTLLVFAFVILLVAPGAAGSDFLKDSGNPLVEALEAPGAYGGQNLVSQFINLVGLLGLI
ASFFSIIFAYSRQTFALSRAGYLPKFLSLTGQRKTPYVALIVPGIIGFVMAVLNQGDLLILVAVFGATISYVMMTLSHII
LRFKEPELDRPYRTPGGVVTTGIACVLGVVALIAGFLVDTRVVAITAGVYVIAIAYFGLYSRHHIVASAPEEEFALIESS
ESELH

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=373, Percent_Identity=23.3243967828418, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI258614005, Length=374, Percent_Identity=22.9946524064171, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI258614003, Length=374, Percent_Identity=22.9946524064171, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4507047, Length=380, Percent_Identity=23.1578947368421, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI181337167, Length=338, Percent_Identity=24.2603550295858, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1786602, Length=397, Percent_Identity=23.4256926952141, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790653, Length=396, Percent_Identity=22.979797979798, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786789, Length=398, Percent_Identity=22.3618090452261, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786302, Length=365, Percent_Identity=22.7397260273973, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789017, Length=362, Percent_Identity=23.2044198895028, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=368, Percent_Identity=22.8260869565217, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324059, Length=325, Percent_Identity=24.3076923076923, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321629, Length=412, Percent_Identity=24.7572815533981, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324061, Length=430, Percent_Identity=23.0232558139535, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221512776, Length=378, Percent_Identity=26.4550264550265, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24666159, Length=378, Percent_Identity=26.4550264550265, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24668806, Length=366, Percent_Identity=21.8579234972678, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356285, Length=366, Percent_Identity=21.8579234972678, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24668802, Length=366, Percent_Identity=21.8579234972678, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667468, Length=370, Percent_Identity=23.5135135135135, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI161077963, Length=337, Percent_Identity=22.5519287833828, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51438; Mature: 51307

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQAPRRIHERGGIDASVEGTEYFEKRQLAGGVAGWLLLAGLGVAYVISGDFAGWNFGM
CCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
GEGGWGGMLIATGLMGTMYLFMVLGLAELSSTISTTGGGYAFARRAMGPWGGFLTGTAIL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
IEYAIAPAAIANFIGAYVESLTGFDVGWVVFLVFYAVFIGLHLWGVGEALKLMFVITAIA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVALFVFVIAALPKFDASNLNSIPVDTSAFGSSSFLPFGLVGIWAALPYAIWFYLAVEGV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PLAAEESKDPAKDMPRGIIAAIVTLLVFAFVILLVAPGAAGSDFLKDSGNPLVEALEAPG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHCCC
AYGGQNLVSQFINLVGLLGLIASFFSIIFAYSRQTFALSRAGYLPKFLSLTGQRKTPYVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCCCCEEE
LIVPGIIGFVMAVLNQGDLLILVAVFGATISYVMMTLSHIILRFKEPELDRPYRTPGGVV
EHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
TTGIACVLGVVALIAGFLVDTRVVAITAGVYVIAIAYFGLYSRHHIVASAPEEEFALIES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHCC
SESELH
CHHCCC
>Mature Secondary Structure 
SEQAPRRIHERGGIDASVEGTEYFEKRQLAGGVAGWLLLAGLGVAYVISGDFAGWNFGM
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC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CHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]