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The map label for this gene is gcp

Identifier: 119717879

GI number: 119717879

Start: 3882932

End: 3883978

Strand: Reverse

Name: gcp

Synonym: Noca_3657

Alternate gene names: 119717879

Gene position: 3883978-3882932 (Counterclockwise)

Preceding gene: 119717880

Following gene: 119717875

Centisome position: 77.9

GC content: 74.31

Gene sequence:

>1047_bases
GTGAGCAGCGAACCCCTGGTCCTCGGCATCGAGACCTCGTGCGACGAGACCGGTGTCGGCATCGTCCGTGGGCACACCCT
GCTCGCGGACGCGGTGGCGAGCAGCGTCGACGAGCACGCCCGCTTCGGCGGGGTGGTGCCCGAGGTCGCGAGTCGCGCCC
ACCTCGAGGCGATGGTGCCGACCATCGAACGGGCCTGCGAGACGGCCGGCATCCGCCTGTACGACGTCGACGCGATCGCG
GTCACCAGCGGACCGGGGTTGGCCGGGGCGTTGATGGTGGGGGTAGCCGCCGCGAAGGCGCTCGCGGTCGGCCTCGGCAA
GCCGATCTACGGCGTGAACCACCTCGCGGCGCACGTTGCCGTCGACCAGCTCGAGCACGGCCCGCTGCCCGAGCCCTGCC
TCGCGCTGCTGGTCAGCGGCGGCCACTCCAGCCTGCTGCGGGTCGAGGACGTCACCTCCGGGGTGGACCCGATGGGGGCG
ACCATCGACGACGCCGCCGGCGAGGCCTTCGACAAGGTGGCCCGGCTGCTCGGCCTGCCGTTCCCCGGTGGCCCCTACAT
CGACCGTGCGGCCCGCGAGGGCAGCACCGTGTACGTCGACTTCCCGCGCGGCCTGACCAGCCGCCGCGACCTCGAGCGGC
ACCGCTTCGACTTCTCGTTCTCGGGCCTCAAGACCGCGGTCGCGCGGTGGGTCGAGGCACGGGAGCGGTCCGGCGAGCCG
GTGCCGGTGGCCGACGTGGCGGCGAGCTTCCAGGAGGCGGTCTGCGACGTGCTGACCCGCAAGGCGATCGACGCGGCGTC
CAGTGCGGGCATCGAGGACCTCCTCATCGGCGGTGGGGTCGCCGCGAACTCCCGGCTGCGCGTGCTGGCGGAGGAGCGCG
CCGCGGCGCGGGGGATCCGGGTCCGGGTGCCCCGTCCCGGCCTGTGCACCGACAACGGCGCCATGGTCGCCGCTCTGGGC
GCCGAGATGGTCGCCCGCGGCCGCACCCCGTCCCCCCTGGACCTCCCCGCCGACTCCTCGCTCCCCGTGACCGAGGTTCT
CGTCTGA

Upstream 100 bases:

>100_bases
AGCGCGTAGGGACTTCCACGGCTGGAGGGGTCCGAGAAGTGGGACACACCCGTAAGAGGGTGGCCGATCGCCGGCGTGCC
CCGGTCGGCACAATGGAGCG

Downstream 100 bases:

>100_bases
GGACCACTCCGCTGCGGTAGTCCCTGACGTTTGCGCGGTGTGGGAACGCTCCCGAGCCCCACAACCGTCAGGGAGTATCC
GCGGCGGCGGGGACCTCGGA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSSEPLVLGIETSCDETGVGIVRGHTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVPTIERACETAGIRLYDVDAIA
VTSGPGLAGALMVGVAAAKALAVGLGKPIYGVNHLAAHVAVDQLEHGPLPEPCLALLVSGGHSSLLRVEDVTSGVDPMGA
TIDDAAGEAFDKVARLLGLPFPGGPYIDRAAREGSTVYVDFPRGLTSRRDLERHRFDFSFSGLKTAVARWVEARERSGEP
VPVADVAASFQEAVCDVLTRKAIDAASSAGIEDLLIGGGVAANSRLRVLAEERAAARGIRVRVPRPGLCTDNGAMVAALG
AEMVARGRTPSPLDLPADSSLPVTEVLV

Sequences:

>Translated_348_residues
MSSEPLVLGIETSCDETGVGIVRGHTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVPTIERACETAGIRLYDVDAIA
VTSGPGLAGALMVGVAAAKALAVGLGKPIYGVNHLAAHVAVDQLEHGPLPEPCLALLVSGGHSSLLRVEDVTSGVDPMGA
TIDDAAGEAFDKVARLLGLPFPGGPYIDRAAREGSTVYVDFPRGLTSRRDLERHRFDFSFSGLKTAVARWVEARERSGEP
VPVADVAASFQEAVCDVLTRKAIDAASSAGIEDLLIGGGVAANSRLRVLAEERAAARGIRVRVPRPGLCTDNGAMVAALG
AEMVARGRTPSPLDLPADSSLPVTEVLV
>Mature_347_residues
SSEPLVLGIETSCDETGVGIVRGHTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVPTIERACETAGIRLYDVDAIAV
TSGPGLAGALMVGVAAAKALAVGLGKPIYGVNHLAAHVAVDQLEHGPLPEPCLALLVSGGHSSLLRVEDVTSGVDPMGAT
IDDAAGEAFDKVARLLGLPFPGGPYIDRAAREGSTVYVDFPRGLTSRRDLERHRFDFSFSGLKTAVARWVEARERSGEPV
PVADVAASFQEAVCDVLTRKAIDAASSAGIEDLLIGGGVAANSRLRVLAEERAAARGIRVRVPRPGLCTDNGAMVAALGA
EMVARGRTPSPLDLPADSSLPVTEVLV

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=344, Percent_Identity=32.2674418604651, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI8923380, Length=330, Percent_Identity=31.5151515151515, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1789445, Length=315, Percent_Identity=45.0793650793651, Blast_Score=243, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI71995670, Length=326, Percent_Identity=31.5950920245399, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17557464, Length=335, Percent_Identity=31.3432835820896, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=375, Percent_Identity=29.0666666666667, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6322891, Length=350, Percent_Identity=26.2857142857143, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI20129063, Length=354, Percent_Identity=35.0282485875706, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI21357207, Length=337, Percent_Identity=29.673590504451, Blast_Score=131, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_NOCSJ (A1SMX2)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924844.1
- ProteinModelPortal:   A1SMX2
- SMR:   A1SMX2
- STRING:   A1SMX2
- MEROPS:   M22.001
- GeneID:   4595769
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3657
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PLYGVNH
- ProtClustDB:   PRK09604
- BioCyc:   NSP35761:NOCA_3657-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35985; Mature: 35854

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEPLVLGIETSCDETGVGIVRGHTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVP
CCCCCEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TIERACETAGIRLYDVDAIAVTSGPGLAGALMVGVAAAKALAVGLGKPIYGVNHLAAHVA
HHHHHHHHCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VDQLEHGPLPEPCLALLVSGGHSSLLRVEDVTSGVDPMGATIDDAAGEAFDKVARLLGLP
HHHHCCCCCCHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCC
FPGGPYIDRAAREGSTVYVDFPRGLTSRRDLERHRFDFSFSGLKTAVARWVEARERSGEP
CCCCCHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
VPVADVAASFQEAVCDVLTRKAIDAASSAGIEDLLIGGGVAANSRLRVLAEERAAARGIR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCHHHHHHHHHHHHCCCE
VRVPRPGLCTDNGAMVAALGAEMVARGRTPSPLDLPADSSLPVTEVLV
EECCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
SSEPLVLGIETSCDETGVGIVRGHTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVP
CCCCEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TIERACETAGIRLYDVDAIAVTSGPGLAGALMVGVAAAKALAVGLGKPIYGVNHLAAHVA
HHHHHHHHCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VDQLEHGPLPEPCLALLVSGGHSSLLRVEDVTSGVDPMGATIDDAAGEAFDKVARLLGLP
HHHHCCCCCCHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCC
FPGGPYIDRAAREGSTVYVDFPRGLTSRRDLERHRFDFSFSGLKTAVARWVEARERSGEP
CCCCCHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
VPVADVAASFQEAVCDVLTRKAIDAASSAGIEDLLIGGGVAANSRLRVLAEERAAARGIR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCHHHHHHHHHHHHCCCE
VRVPRPGLCTDNGAMVAALGAEMVARGRTPSPLDLPADSSLPVTEVLV
EECCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA