| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is yqjQ [H]
Identifier: 119717783
GI number: 119717783
Start: 3776860
End: 3777690
Strand: Reverse
Name: yqjQ [H]
Synonym: Noca_3561
Alternate gene names: 119717783
Gene position: 3777690-3776860 (Counterclockwise)
Preceding gene: 119717784
Following gene: 119717782
Centisome position: 75.77
GC content: 74.13
Gene sequence:
>831_bases TTGAGTCGTCAGATCTCCGGCATGTCCATCATCGTGACGGGCGGCGCCCGCGGCATCGGGAGGGCCACGGTCGAGCGGTT CGCCCGGCAGGGCGCCTCGGTCGCCATCGGCGACCTCGACGCCGAGCTGGCCGAGGAGGTCGCGGCGGCGTACGGCGACC GCGTGGTCGCCGCGCGGCTCGACGTCACCGACCCGGCCTCGTGGCGGGAGTTCCTCGGCGAGGTCGCCCACCTCGGGCCG TGGGACGTGCTGGTCAACAACGCCGGCATCATGCCGCTCGGCTCGGTGCTCAAGGAGCCCGACGAGGTGACCCGGGCGAT CTTCAACGTCAACGTGCACGGTCCGATCAACGGCACGAAGGCGGTCGCGCCGGGGATGGCCGAGCGCGGCCACGGCCACA TCGTCAACGTCGCCTCCGCCGTCGGCCGGCTCGCGGTCGCCGACGGCGCGTCGTACTCCGCCTCGAAGTTCGCCGTCGTC GGGTTCAGCGAGGCCACCCGGGCCGAGCTCGGACCGCTCGGCATCGACGTCTCCCTGGTGCTGCCGACGGTGGTGCAGAC CGAGCTCTCCGCCGGCATCCCGGCCGCGAAGGGCGTGCCGCCGGTGACGGCCGACGACGTCGCCGCGGTCATCGAGAGCG TCGTGCGCAAGCCGCGGGCAGAGGTGTGGGTGCCGCGCTGGGTGCAGGGGCCGACCAAGGTCACCCAGGCGCTGCCGCGG CGGGTCCAGGACGCGATGGCCAGGGCGATGGGCGCCGACGACGTGCTCGCGAAGGCAGACCCGGCCGCACGCGCGGCGTA CGAACAGCGCGCCCGGCGCGGCGCGGAATAG
Upstream 100 bases:
>100_bases TCGACCCCGGGTACGCCGCGCCGTACGACAACCACTCGCTGCCCTTCGCCAAGGACGGCCAGCCCATCGACCTCGTCCGC ACCGACCCCCGAGGTGAATC
Downstream 100 bases:
>100_bases GCGCCACCGGTCGTCCGGTTGCAGACTGGCAGTGCCACGACGACCGGAAGGCCCCGCACGCCCATGACGACGACCGCGCC CGCAGCGGGGCTGGCGCCGA
Product: short chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 276; Mature: 275
Protein sequence:
>276_residues MSRQISGMSIIVTGGARGIGRATVERFARQGASVAIGDLDAELAEEVAAAYGDRVVAARLDVTDPASWREFLGEVAHLGP WDVLVNNAGIMPLGSVLKEPDEVTRAIFNVNVHGPINGTKAVAPGMAERGHGHIVNVASAVGRLAVADGASYSASKFAVV GFSEATRAELGPLGIDVSLVLPTVVQTELSAGIPAAKGVPPVTADDVAAVIESVVRKPRAEVWVPRWVQGPTKVTQALPR RVQDAMARAMGADDVLAKADPAARAAYEQRARRGAE
Sequences:
>Translated_276_residues MSRQISGMSIIVTGGARGIGRATVERFARQGASVAIGDLDAELAEEVAAAYGDRVVAARLDVTDPASWREFLGEVAHLGP WDVLVNNAGIMPLGSVLKEPDEVTRAIFNVNVHGPINGTKAVAPGMAERGHGHIVNVASAVGRLAVADGASYSASKFAVV GFSEATRAELGPLGIDVSLVLPTVVQTELSAGIPAAKGVPPVTADDVAAVIESVVRKPRAEVWVPRWVQGPTKVTQALPR RVQDAMARAMGADDVLAKADPAARAAYEQRARRGAE >Mature_275_residues SRQISGMSIIVTGGARGIGRATVERFARQGASVAIGDLDAELAEEVAAAYGDRVVAARLDVTDPASWREFLGEVAHLGPW DVLVNNAGIMPLGSVLKEPDEVTRAIFNVNVHGPINGTKAVAPGMAERGHGHIVNVASAVGRLAVADGASYSASKFAVVG FSEATRAELGPLGIDVSLVLPTVVQTELSAGIPAAKGVPPVTADDVAAVIESVVRKPRAEVWVPRWVQGPTKVTQALPRR VQDAMARAMGADDVLAKADPAARAAYEQRARRGAE
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI210032110, Length=253, Percent_Identity=30.8300395256917, Blast_Score=119, Evalue=4e-27, Organism=Homo sapiens, GI25282469, Length=290, Percent_Identity=28.9655172413793, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI142976729, Length=246, Percent_Identity=28.8617886178862, Blast_Score=105, Evalue=6e-23, Organism=Homo sapiens, GI210032112, Length=249, Percent_Identity=28.5140562248996, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI40807363, Length=262, Percent_Identity=27.4809160305344, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=30.5, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI7657478, Length=194, Percent_Identity=33.5051546391753, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI40548397, Length=196, Percent_Identity=31.6326530612245, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI214010158, Length=196, Percent_Identity=31.6326530612245, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI214010156, Length=196, Percent_Identity=31.6326530612245, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI22758144, Length=196, Percent_Identity=31.6326530612245, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI310128830, Length=294, Percent_Identity=24.4897959183673, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI310115468, Length=294, Percent_Identity=24.4897959183673, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI7705925, Length=191, Percent_Identity=35.6020942408377, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI40254992, Length=180, Percent_Identity=34.4444444444444, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503817, Length=185, Percent_Identity=30.8108108108108, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=31.9371727748691, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=30.2564102564103, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI50726952, Length=196, Percent_Identity=31.6326530612245, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI15277342, Length=197, Percent_Identity=31.4720812182741, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI44680136, Length=184, Percent_Identity=30.9782608695652, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI44680133, Length=184, Percent_Identity=30.9782608695652, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI17738292, Length=184, Percent_Identity=30.9782608695652, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=30.8457711442786, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4758504, Length=206, Percent_Identity=32.5242718446602, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI157739938, Length=240, Percent_Identity=27.9166666666667, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI19743808, Length=191, Percent_Identity=31.9371727748691, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI22507405, Length=194, Percent_Identity=32.4742268041237, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI7705855, Length=273, Percent_Identity=27.1062271062271, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI32483357, Length=186, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=30.9941520467836, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI4504503, Length=183, Percent_Identity=31.6939890710383, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI83715985, Length=230, Percent_Identity=31.7391304347826, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI166795268, Length=207, Percent_Identity=31.8840579710145, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=32.4324324324324, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI66933014, Length=185, Percent_Identity=32.4324324324324, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI5031737, Length=185, Percent_Identity=32.4324324324324, Blast_Score=68, Evalue=1e-11, Organism=Escherichia coli, GI1787335, Length=182, Percent_Identity=35.7142857142857, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI87082100, Length=195, Percent_Identity=34.3589743589744, Blast_Score=97, Evalue=2e-21, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=34.9462365591398, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI2367365, Length=189, Percent_Identity=34.3915343915344, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1790717, Length=196, Percent_Identity=31.6326530612245, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI87082160, Length=189, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1786701, Length=217, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1788459, Length=186, Percent_Identity=30.6451612903226, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI2367175, Length=192, Percent_Identity=30.2083333333333, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193203117, Length=257, Percent_Identity=29.5719844357977, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI193203115, Length=260, Percent_Identity=28.8461538461538, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17567345, Length=270, Percent_Identity=27.4074074074074, Blast_Score=104, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17508895, Length=255, Percent_Identity=28.6274509803922, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17564282, Length=268, Percent_Identity=26.865671641791, Blast_Score=95, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17555706, Length=215, Percent_Identity=32.093023255814, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI25147288, Length=210, Percent_Identity=30, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17561402, Length=197, Percent_Identity=30.9644670050761, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17559104, Length=206, Percent_Identity=35.4368932038835, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI71994600, Length=187, Percent_Identity=29.9465240641711, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560150, Length=223, Percent_Identity=30.4932735426009, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71994604, Length=186, Percent_Identity=31.7204301075269, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17565030, Length=216, Percent_Identity=32.8703703703704, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17562904, Length=212, Percent_Identity=32.0754716981132, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17562990, Length=215, Percent_Identity=30.6976744186047, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI32563809, Length=205, Percent_Identity=30.2439024390244, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17507613, Length=205, Percent_Identity=30.2439024390244, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI72000259, Length=240, Percent_Identity=31.6666666666667, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17568967, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17563726, Length=206, Percent_Identity=30.0970873786408, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538182, Length=205, Percent_Identity=32.1951219512195, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI193204405, Length=222, Percent_Identity=31.0810810810811, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=234, Percent_Identity=32.9059829059829, Blast_Score=93, Evalue=6e-20, Organism=Saccharomyces cerevisiae, GI6322861, Length=186, Percent_Identity=26.8817204301075, Blast_Score=70, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6322067, Length=171, Percent_Identity=30.4093567251462, Blast_Score=66, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6323458, Length=228, Percent_Identity=27.6315789473684, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI24581726, Length=259, Percent_Identity=30.1158301158301, Blast_Score=101, Evalue=7e-22, Organism=Drosophila melanogaster, GI21355631, Length=268, Percent_Identity=30.2238805970149, Blast_Score=97, Evalue=8e-21, Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=33.502538071066, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24639444, Length=195, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI281364892, Length=251, Percent_Identity=28.6852589641434, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI221510726, Length=206, Percent_Identity=32.0388349514563, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24640492, Length=253, Percent_Identity=26.4822134387352, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24649181, Length=256, Percent_Identity=28.515625, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI17737361, Length=213, Percent_Identity=34.2723004694836, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI21355319, Length=198, Percent_Identity=30.3030303030303, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI21357041, Length=185, Percent_Identity=35.6756756756757, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI23397609, Length=192, Percent_Identity=35.4166666666667, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=31.9796954314721, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI28571526, Length=189, Percent_Identity=33.8624338624339, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI21356301, Length=194, Percent_Identity=30.4123711340206, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI24643142, Length=195, Percent_Identity=32.3076923076923, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI116007236, Length=224, Percent_Identity=29.0178571428571, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24641232, Length=195, Percent_Identity=31.7948717948718, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=29.9492385786802, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24665243, Length=225, Percent_Identity=28.8888888888889, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 28705; Mature: 28574
Theoretical pI: Translated: 6.54; Mature: 6.54
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSRQISGMSIIVTGGARGIGRATVERFARQGASVAIGDLDAELAEEVAAAYGDRVVAARL CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCEEEEEEE DVTDPASWREFLGEVAHLGPWDVLVNNAGIMPLGSVLKEPDEVTRAIFNVNVHGPINGTK CCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHCCHHHHHHHHHEEEECCCCCCCH AVAPGMAERGHGHIVNVASAVGRLAVADGASYSASKFAVVGFSEATRAELGPLGIDVSLV HHCCCCHHCCCCCEEEHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHCCCCCCCHHHH LPTVVQTELSAGIPAAKGVPPVTADDVAAVIESVVRKPRAEVWVPRWVQGPTKVTQALPR HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHH RVQDAMARAMGADDVLAKADPAARAAYEQRARRGAE HHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHCCCC >Mature Secondary Structure SRQISGMSIIVTGGARGIGRATVERFARQGASVAIGDLDAELAEEVAAAYGDRVVAARL CCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCEEEEEEE DVTDPASWREFLGEVAHLGPWDVLVNNAGIMPLGSVLKEPDEVTRAIFNVNVHGPINGTK CCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHCCHHHHHHHHHEEEECCCCCCCH AVAPGMAERGHGHIVNVASAVGRLAVADGASYSASKFAVVGFSEATRAELGPLGIDVSLV HHCCCCHHCCCCCEEEHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHCCCCCCCHHHH LPTVVQTELSAGIPAAKGVPPVTADDVAAVIESVVRKPRAEVWVPRWVQGPTKVTQALPR HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHH RVQDAMARAMGADDVLAKADPAARAAYEQRARRGAE HHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8969508; 9384377 [H]