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The map label for this gene is obgE

Identifier: 119717671

GI number: 119717671

Start: 3656400

End: 3657950

Strand: Reverse

Name: obgE

Synonym: Noca_3449

Alternate gene names: 119717671

Gene position: 3657950-3656400 (Counterclockwise)

Preceding gene: 119717672

Following gene: 119717670

Centisome position: 73.37

GC content: 74.27

Gene sequence:

>1551_bases
ATGGCAGTCCCGACCTTCGTCGACCGCGTGACGCTGCACGTCAGCGCCGGGCGCGGCGGCAACGGCGTGGCGTCCGTGCA
CCGGGAGAAGTTCAAGCCGCTCGGCGGCCCCGACGGCGGCAACGGTGGTCCGGGCGGATCGGTGACCCTGCGGGTCGACC
CCGACGTGACCACGTTGCTGGACTACCACCACAGCCCCAAGCGGCGCGCCGAGCACGGCGGTCACGGCGCGGGTGCGCAC
CGCAACGGCGCTCACGGCGCCGACCTGGTGCTCCCGGTGCCGGACGGCACGGTCGTGAGCGACCCGCAGGGACACCTGCT
GGCCGACCTGGTCGGACCCGGCACCGAGCTGGTCGTCGCCCAGGGCGGCCGGGGTGGTCTCGGCAACGCGGCACTGGCCT
CGGCCAAGCGCAAGGCGCCCGGCTTCGCGCTGCTCGGCGAGCCGGGCGACGAGCTGGAGATCGTGCTCGAGCTCAAGGTG
GTGGCCGACATCGGGTTGGTCGGGTTCCCCAGCGCCGGCAAGTCCAGCCTGATCGCGGCGATCTCGCGGGCCCGGCCCAA
GATCGCCGACTACCCGTTCACGACCCTGGTGCCCAACCTCGGCGTGGTGTCCGCCGGCGACACGACGTTCACCGTCGCCG
ACGTGCCCGGCCTGATCGAGGGCGCGAGCGAGGGCCGTGGCCTCGGCCACGACTTCCTGCGCCACATCGAGCGCTGCGCC
GCGATCGTGCACGTGGTGGACACCGCGAGCATCGAGCCGGGCCGCAACCCGGTCGACGACCTCGACGTGATCGAGAACGA
GCTGACCCGGTACGGCGGCCTCGAGGACCGGCCGCGCCTGGTGGCGCTGAACAAGGTCGACGTCCCGGACGGCCGCGACA
TCGCCGGCTTCGTCGTCGACGAGCTGCGCCAGCGCGGGCTGCGCGTCTTCGAGGTCTCCGCGGCCTCCGGCGAGGGCCTG
CGCGAGCTCACCTTCGCGATGGCGGGCATCGTCGAGGCGGCCCGCGCCGCGAAGCCGGCGGTCGAGGCCACCCGGATCGT
GCTGCGCCCGCCCTCGGTCGACGGCAGCGACGCGTTCACCGTCACCGCGACCCCGGACGGCTGGCGGGTCCGGGGCGAGA
AGCCGGAGCGCTGGGTGCGGCAGACCGACTTCAGCAACGACGAGGCCGTGGGCTTCCTCGCCGACCGGCTCAACCGGCTC
GGCGTCGAGACCCGGCTGGCCGAGATGGGTGCGGAGGAGGGGGACGCCGTCCTCATCGGCGACCCCGAGAACGCGGTCGT
GTTCGACTTCAAGCCCGGGGTCGACGCGGCGGCCGAGATCCTCAGCCGGCGCGGCGAGGACCAGCGCTTCGACGAGTCGC
GGCCCGCGGCGCGGCGCCGCCGGGCCATCGAGGAGGCGATGGCGGACCGGGCTGAGGGCGAGACCCGCGCTGACGTCGCC
CGTCGGCTCGACCGGCCCGCCCGTGAGGACGGCGGAGCCTACGGGCCGCAGTCCTACGAGATCGGCGGCAGGGACGACCC
GGACTGGGCCGAGGAGGATCTCGGGGAATGA

Upstream 100 bases:

>100_bases
TGACCTGACGCTCGCATCCCACGCAGCAGCTGCGAACGGGCGTCCCTGACGGGGCGCCCGTTTCTGCATTTCCACCGAGT
TCTCCGAGAGAGTAGGCACC

Downstream 100 bases:

>100_bases
GCAGGAGATGAGGCAGTCATGAGCCTGCGCCACGAGGTCACCGAGGCGAAGCGGATCGTCGTCAAGATCGGTTCCTCCTC
GCTCACCACGGCGGCCGGCG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MAVPTFVDRVTLHVSAGRGGNGVASVHREKFKPLGGPDGGNGGPGGSVTLRVDPDVTTLLDYHHSPKRRAEHGGHGAGAH
RNGAHGADLVLPVPDGTVVSDPQGHLLADLVGPGTELVVAQGGRGGLGNAALASAKRKAPGFALLGEPGDELEIVLELKV
VADIGLVGFPSAGKSSLIAAISRARPKIADYPFTTLVPNLGVVSAGDTTFTVADVPGLIEGASEGRGLGHDFLRHIERCA
AIVHVVDTASIEPGRNPVDDLDVIENELTRYGGLEDRPRLVALNKVDVPDGRDIAGFVVDELRQRGLRVFEVSAASGEGL
RELTFAMAGIVEAARAAKPAVEATRIVLRPPSVDGSDAFTVTATPDGWRVRGEKPERWVRQTDFSNDEAVGFLADRLNRL
GVETRLAEMGAEEGDAVLIGDPENAVVFDFKPGVDAAAEILSRRGEDQRFDESRPAARRRRAIEEAMADRAEGETRADVA
RRLDRPAREDGGAYGPQSYEIGGRDDPDWAEEDLGE

Sequences:

>Translated_516_residues
MAVPTFVDRVTLHVSAGRGGNGVASVHREKFKPLGGPDGGNGGPGGSVTLRVDPDVTTLLDYHHSPKRRAEHGGHGAGAH
RNGAHGADLVLPVPDGTVVSDPQGHLLADLVGPGTELVVAQGGRGGLGNAALASAKRKAPGFALLGEPGDELEIVLELKV
VADIGLVGFPSAGKSSLIAAISRARPKIADYPFTTLVPNLGVVSAGDTTFTVADVPGLIEGASEGRGLGHDFLRHIERCA
AIVHVVDTASIEPGRNPVDDLDVIENELTRYGGLEDRPRLVALNKVDVPDGRDIAGFVVDELRQRGLRVFEVSAASGEGL
RELTFAMAGIVEAARAAKPAVEATRIVLRPPSVDGSDAFTVTATPDGWRVRGEKPERWVRQTDFSNDEAVGFLADRLNRL
GVETRLAEMGAEEGDAVLIGDPENAVVFDFKPGVDAAAEILSRRGEDQRFDESRPAARRRRAIEEAMADRAEGETRADVA
RRLDRPAREDGGAYGPQSYEIGGRDDPDWAEEDLGE
>Mature_515_residues
AVPTFVDRVTLHVSAGRGGNGVASVHREKFKPLGGPDGGNGGPGGSVTLRVDPDVTTLLDYHHSPKRRAEHGGHGAGAHR
NGAHGADLVLPVPDGTVVSDPQGHLLADLVGPGTELVVAQGGRGGLGNAALASAKRKAPGFALLGEPGDELEIVLELKVV
ADIGLVGFPSAGKSSLIAAISRARPKIADYPFTTLVPNLGVVSAGDTTFTVADVPGLIEGASEGRGLGHDFLRHIERCAA
IVHVVDTASIEPGRNPVDDLDVIENELTRYGGLEDRPRLVALNKVDVPDGRDIAGFVVDELRQRGLRVFEVSAASGEGLR
ELTFAMAGIVEAARAAKPAVEATRIVLRPPSVDGSDAFTVTATPDGWRVRGEKPERWVRQTDFSNDEAVGFLADRLNRLG
VETRLAEMGAEEGDAVLIGDPENAVVFDFKPGVDAAAEILSRRGEDQRFDESRPAARRRRAIEEAMADRAEGETRADVAR
RLDRPAREDGGAYGPQSYEIGGRDDPDWAEEDLGE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=330, Percent_Identity=43.030303030303, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI111955139, Length=287, Percent_Identity=36.9337979094077, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI111955063, Length=180, Percent_Identity=38.8888888888889, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI58761500, Length=128, Percent_Identity=31.25, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=35.4330708661417, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1789574, Length=345, Percent_Identity=43.768115942029, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1787454, Length=128, Percent_Identity=37.5, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17508313, Length=286, Percent_Identity=40.9090909090909, Blast_Score=149, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=307, Percent_Identity=31.2703583061889, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=149, Percent_Identity=31.5436241610738, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17555344, Length=111, Percent_Identity=35.1351351351351, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=72, Percent_Identity=41.6666666666667, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=153, Percent_Identity=43.1372549019608, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6319281, Length=108, Percent_Identity=35.1851851851852, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=94, Percent_Identity=36.1702127659575, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=153, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321649, Length=149, Percent_Identity=29.5302013422819, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129375, Length=321, Percent_Identity=37.6947040498442, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24585318, Length=294, Percent_Identity=36.3945578231293, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=35.15625, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=35.15625, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=35.15625, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17981711, Length=111, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_NOCSJ (A1SMB4)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924636.1
- ProteinModelPortal:   A1SMB4
- SMR:   A1SMB4
- STRING:   A1SMB4
- GeneID:   4597265
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3449
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12296
- BioCyc:   NSP35761:NOCA_3449-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 54487; Mature: 54356

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPTFVDRVTLHVSAGRGGNGVASVHREKFKPLGGPDGGNGGPGGSVTLRVDPDVTTLL
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHH
DYHHSPKRRAEHGGHGAGAHRNGAHGADLVLPVPDGTVVSDPQGHLLADLVGPGTELVVA
HHCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCEEEECCCCCCEEEEE
QGGRGGLGNAALASAKRKAPGFALLGEPGDELEIVLELKVVADIGLVGFPSAGKSSLIAA
ECCCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEEHHCCEEECCCCCHHHHHHH
ISRARPKIADYPFTTLVPNLGVVSAGDTTFTVADVPGLIEGASEGRGLGHDFLRHIERCA
HHHCCCCCCCCCHHHHCCCCCEEECCCCEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHH
AIVHVVDTASIEPGRNPVDDLDVIENELTRYGGLEDRPRLVALNKVDVPDGRDIAGFVVD
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHH
ELRQRGLRVFEVSAASGEGLRELTFAMAGIVEAARAAKPAVEATRIVLRPPSVDGSDAFT
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEE
VTATPDGWRVRGEKPERWVRQTDFSNDEAVGFLADRLNRLGVETRLAEMGAEEGDAVLIG
EEECCCCCEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEE
DPENAVVFDFKPGVDAAAEILSRRGEDQRFDESRPAARRRRAIEEAMADRAEGETRADVA
CCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
RRLDRPAREDGGAYGPQSYEIGGRDDPDWAEEDLGE
HHHCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
AVPTFVDRVTLHVSAGRGGNGVASVHREKFKPLGGPDGGNGGPGGSVTLRVDPDVTTLL
CCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHH
DYHHSPKRRAEHGGHGAGAHRNGAHGADLVLPVPDGTVVSDPQGHLLADLVGPGTELVVA
HHCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCEEEECCCCCCEEEEE
QGGRGGLGNAALASAKRKAPGFALLGEPGDELEIVLELKVVADIGLVGFPSAGKSSLIAA
ECCCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEEHHCCEEECCCCCHHHHHHH
ISRARPKIADYPFTTLVPNLGVVSAGDTTFTVADVPGLIEGASEGRGLGHDFLRHIERCA
HHHCCCCCCCCCHHHHCCCCCEEECCCCEEEEECCCHHHCCCCCCCCCCHHHHHHHHHHH
AIVHVVDTASIEPGRNPVDDLDVIENELTRYGGLEDRPRLVALNKVDVPDGRDIAGFVVD
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHH
ELRQRGLRVFEVSAASGEGLRELTFAMAGIVEAARAAKPAVEATRIVLRPPSVDGSDAFT
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEE
VTATPDGWRVRGEKPERWVRQTDFSNDEAVGFLADRLNRLGVETRLAEMGAEEGDAVLIG
EEECCCCCEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEE
DPENAVVFDFKPGVDAAAEILSRRGEDQRFDESRPAARRRRAIEEAMADRAEGETRADVA
CCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
RRLDRPAREDGGAYGPQSYEIGGRDDPDWAEEDLGE
HHHCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA