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The map label for this gene is entA [C]

Identifier: 119717528

GI number: 119717528

Start: 3510465

End: 3511205

Strand: Reverse

Name: entA [C]

Synonym: Noca_3304

Alternate gene names: 119717528

Gene position: 3511205-3510465 (Counterclockwise)

Preceding gene: 119717529

Following gene: 119717527

Centisome position: 70.42

GC content: 75.98

Gene sequence:

>741_bases
GTGGCGACCGGATCGGCGGGGGTGGCGATGGTGACCGGCGCGAGCGGCCGGATCGGCCGGCACGTCGTCGACCGGCTGAT
CGAGCGCGGGTACGCCGTGCAGGGGCTCGACCTGGCACCCGGTCCGCACACCCGGGTCTGCGACCTCGCCGACGAGGACG
CGGTCCGCGCGGCGCTGGGCGACCTGCCGCGGCTGGACCTGCTCGTGCTCTGCGCCGGCCTGTCCGCGATCGGGACCGTC
GACGACCACGATCTCGCCACCCACCGGCGGGTCATGGACGGCACCCACTTCTCGGCCGTGGGGCCGCTGCTGGCCGCGTT
GCCGGCGTTGCGGCGGGCCCGGGGCACCGTGGTGCTGGTGGGGTCGGTGGCGGGCTTCGCGCCCGTGCTCGGCCGCCCGG
CGTACGTCGCCGCCAAGAACGCGGTCACCGGCCTGTTCACCGCGCTGCGTCCCGAGCTGGCTGCCCAAGGGGTGCGCGTC
GTGGTCGTGCACCCGACGTTCGTCACCGGCGGCATGGGGGTGGCCGACCAGGCCGGGTACGACCGTCGCACGACCGCCGG
CGCCGAGCTCACGCCGGAGCAGGTGGCCGACGCCATCGTCGATGCGGCCGAGGGACGGCGCGACGTCGTCCTCGTGGGTC
GCACGGCCCGCCTGGCCTGGGCGGTGAGCAGGCACGCCCCTCGGACCTACACCCGCCTGATGACCCGTCGGCTGCGCGCC
GGGACAGGAGAGAACCCGTGA

Upstream 100 bases:

>100_bases
GACAACAGCCGGCTGCGCCGCGACTTCCCGGGGCTCCCGACCCTGACGACCCGCGAGACCTACGAGGTCTTCCGCCAGGG
CCGGTCGGGACGGGGCTGAC

Downstream 100 bases:

>100_bases
ATGACCCGTTGCTGTCCCTGGTCGCGATGGCCGACAACGTCGACGACATCAAGATCGCGTTCGACGAGAGCTCCCGGATG
CTGCTGCGCGTCATCATCGC

Product: short-chain dehydrogenase/reductase SDR

Products: 2,3-Dihydroxybenzoate; H+; Nicotinamide adenine dinucleotide - reduced [C]

Alternate protein names: Short-Chain Dehydrogenase/Reductase SDR; Short Chain Dehydrogenase/Reductase Family Oxidoreductase; Short Chain Dehydrogenase

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MATGSAGVAMVTGASGRIGRHVVDRLIERGYAVQGLDLAPGPHTRVCDLADEDAVRAALGDLPRLDLLVLCAGLSAIGTV
DDHDLATHRRVMDGTHFSAVGPLLAALPALRRARGTVVLVGSVAGFAPVLGRPAYVAAKNAVTGLFTALRPELAAQGVRV
VVVHPTFVTGGMGVADQAGYDRRTTAGAELTPEQVADAIVDAAEGRRDVVLVGRTARLAWAVSRHAPRTYTRLMTRRLRA
GTGENP

Sequences:

>Translated_246_residues
MATGSAGVAMVTGASGRIGRHVVDRLIERGYAVQGLDLAPGPHTRVCDLADEDAVRAALGDLPRLDLLVLCAGLSAIGTV
DDHDLATHRRVMDGTHFSAVGPLLAALPALRRARGTVVLVGSVAGFAPVLGRPAYVAAKNAVTGLFTALRPELAAQGVRV
VVVHPTFVTGGMGVADQAGYDRRTTAGAELTPEQVADAIVDAAEGRRDVVLVGRTARLAWAVSRHAPRTYTRLMTRRLRA
GTGENP
>Mature_245_residues
ATGSAGVAMVTGASGRIGRHVVDRLIERGYAVQGLDLAPGPHTRVCDLADEDAVRAALGDLPRLDLLVLCAGLSAIGTVD
DHDLATHRRVMDGTHFSAVGPLLAALPALRRARGTVVLVGSVAGFAPVLGRPAYVAAKNAVTGLFTALRPELAAQGVRVV
VVHPTFVTGGMGVADQAGYDRRTTAGAELTPEQVADAIVDAAEGRRDVVLVGRTARLAWAVSRHAPRTYTRLMTRRLRAG
TGENP

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI20149619, Length=209, Percent_Identity=30.1435406698565, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI4503817, Length=167, Percent_Identity=32.9341317365269, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=237, Percent_Identity=27.8481012658228, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.3.1.28 [C]

Molecular weight: Translated: 25617; Mature: 25486

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGSAGVAMVTGASGRIGRHVVDRLIERGYAVQGLDLAPGPHTRVCDLADEDAVRAALG
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCEEECCCCHHHHHHHHC
DLPRLDLLVLCAGLSAIGTVDDHDLATHRRVMDGTHFSAVGPLLAALPALRRARGTVVLV
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEE
GSVAGFAPVLGRPAYVAAKNAVTGLFTALRPELAAQGVRVVVVHPTFVTGGMGVADQAGY
ECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCCCC
DRRTTAGAELTPEQVADAIVDAAEGRRDVVLVGRTARLAWAVSRHAPRTYTRLMTRRLRA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHC
GTGENP
CCCCCC
>Mature Secondary Structure 
ATGSAGVAMVTGASGRIGRHVVDRLIERGYAVQGLDLAPGPHTRVCDLADEDAVRAALG
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCEEECCCCHHHHHHHHC
DLPRLDLLVLCAGLSAIGTVDDHDLATHRRVMDGTHFSAVGPLLAALPALRRARGTVVLV
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEE
GSVAGFAPVLGRPAYVAAKNAVTGLFTALRPELAAQGVRVVVVHPTFVTGGMGVADQAGY
ECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCCCC
DRRTTAGAELTPEQVADAIVDAAEGRRDVVLVGRTARLAWAVSRHAPRTYTRLMTRRLRA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHC
GTGENP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 5550 [C]

Specific activity: 66

Km value (mM): 0.26 {methyl-2,3-dehydro-3-hydroxybenzoate}} 0.2 {3-oxocyclohexane-1-carboxylic} 0.3 {2,3-dihydro-2,3-dihydroxybenzoate}} [C]

Substrates: 2,3-Dihydro-2,3-dihydroxybenzoate; Nicotinamide adenine dinucleotide [C]

Specific reaction: 2,3-Dihydro-2,3-dihydroxybenzoate + Nicotinamide adenine dinucleotide <==> 2,3-Dihydroxybenzoate + H+ + Nicotinamide adenine dinucleotide - reduced [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA