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The map label for this gene is hup2 [H]

Identifier: 119717520

GI number: 119717520

Start: 3502342

End: 3502950

Strand: Reverse

Name: hup2 [H]

Synonym: Noca_3296

Alternate gene names: 119717520

Gene position: 3502950-3502342 (Counterclockwise)

Preceding gene: 119717521

Following gene: 119717518

Centisome position: 70.26

GC content: 68.47

Gene sequence:

>609_bases
GTGAACAAGTCAGAGTTCATCGACGCGCTGGCCGCGCGTTACGAGGGGAACCGCAAGGCCGCGGCCCACGCTCTCGAGTC
CGTGCTGGACACGATCACCCGAGAGGTCGCGAAGGGCGAGAAGGTCGCCATCACGGGCTTCGGGTCGTTCGAGAAGCGGG
TCCGTGAGGCGCGCTGGGTGCGGAACCCGCAGACCGGAGCGCGGATCAAGGCCAAGAAGACGGCGGTGCCGAAGTTCACG
GCCGGAGCGGACCTCAAGAACGTCGTCTCGGGTGCCAAGAAGCTCCCGAAGCTGACCCTCGCCGCCGCCCCTGCGGCGGC
GAAGAAGGCCACGGCGGCCGCCAAGAAGGCGGCTCCGGCCAAGAAGGCGGCGCCCGCCAAGAAGACGGCGGCGAAGTCGG
CTCCGGCGAAGAAGACGGCCACCAAGGCCGTCGCCAAGAAGGCGCCCGCCAAGAAGGCTCCGGCCAAGAAGGCACCGGCA
GCGAAGAAGGCTCCGGCGAAGAAGACCGCCACCAAGGCCGTCGCCAAGAAGGCGCCCGCCAAGAAGGCACCGGCCAAGAA
GGCTCCGGCCAAGAAGGCTCCGGCGAAGAAGACCGCCAAGAAGGCCTGA

Upstream 100 bases:

>100_bases
CGCGCGGTGGTGATTGTGACTGGCGCCGCGAATACCTAGCGTGCGTTGAAGAAAGTCGAGCACGGGCTCGACCACTTGTC
GTTCATTGGAAGGGAAGACA

Downstream 100 bases:

>100_bases
CACCGCACCACGGAGCGACGGGCCGCCATCCTCACGGGTGGCGGCCCGTCGTCACGTCCGGGCCGTCGTCACAGCTCGGG
CAGCACGGCCACGGTGTGCG

Product: nucleoid protein Hbs

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MNKSEFIDALAARYEGNRKAAAHALESVLDTITREVAKGEKVAITGFGSFEKRVREARWVRNPQTGARIKAKKTAVPKFT
AGADLKNVVSGAKKLPKLTLAAAPAAAKKATAAAKKAAPAKKAAPAKKTAAKSAPAKKTATKAVAKKAPAKKAPAKKAPA
AKKAPAKKTATKAVAKKAPAKKAPAKKAPAKKAPAKKTAKKA

Sequences:

>Translated_202_residues
MNKSEFIDALAARYEGNRKAAAHALESVLDTITREVAKGEKVAITGFGSFEKRVREARWVRNPQTGARIKAKKTAVPKFT
AGADLKNVVSGAKKLPKLTLAAAPAAAKKATAAAKKAAPAKKAAPAKKTAAKSAPAKKTATKAVAKKAPAKKAPAKKAPA
AKKAPAKKTATKAVAKKAPAKKAPAKKAPAKKAPAKKTAKKA
>Mature_202_residues
MNKSEFIDALAARYEGNRKAAAHALESVLDTITREVAKGEKVAITGFGSFEKRVREARWVRNPQTGARIKAKKTAVPKFT
AGADLKNVVSGAKKLPKLTLAAAPAAAKKATAAAKKAAPAKKAAPAKKTAAKSAPAKKTATKAVAKKAPAKKAPAKKAPA
AKKAPAKKTATKAVAKKAPAKKAPAKKAPAKKAPAKKTAKKA

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=42.2222222222222, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=42.6966292134831, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 20739; Mature: 20739

Theoretical pI: Translated: 11.72; Mature: 11.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSEFIDALAARYEGNRKAAAHALESVLDTITREVAKGEKVAITGFGSFEKRVREARWV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
RNPQTGARIKAKKTAVPKFTAGADLKNVVSGAKKLPKLTLAAAPAAAKKATAAAKKAAPA
CCCCCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCH
KKAAPAKKTAAKSAPAKKTATKAVAKKAPAKKAPAKKAPAAKKAPAKKTATKAVAKKAPA
HHCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
KKAPAKKAPAKKAPAKKTAKKA
CCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MNKSEFIDALAARYEGNRKAAAHALESVLDTITREVAKGEKVAITGFGSFEKRVREARWV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
RNPQTGARIKAKKTAVPKFTAGADLKNVVSGAKKLPKLTLAAAPAAAKKATAAAKKAAPA
CCCCCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCH
KKAAPAKKTAAKSAPAKKTATKAVAKKAPAKKAPAKKAPAAKKAPAKKTATKAVAKKAPA
HHCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
KKAPAKKAPAKKAPAKKTAKKA
CCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]