BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is ephD [H]

Identifier: 119717064

GI number: 119717064

Start: 3009686

End: 3010594

Strand: Reverse

Name: ephD [H]

Synonym: Noca_2840

Alternate gene names: 119717064

Gene position: 3010594-3009686 (Counterclockwise)

Preceding gene: 119717065

Following gene: 119717063

Centisome position: 60.38

GC content: 74.7

Gene sequence:

>909_bases
GTGGTGAGGCGCCGTTGCACCTTCGTGCGCAGCCGACCACGTGACCTGCAGGACGCCAACGTGTTCGTGACCGGCGCCGC
CAGCGGCATCGGCCGGGCCACCGCCGAGCTGCTCGGTCGTCAGGGGGCCCGGCTGCACCTCACCGACGTCGACGCGCCGC
GGCTGGCCGAGTTCGCCGAGCACCTGCGGGCCTGCGGGAGCACCGTGGTGCTGGCCGTACCCGCCGACATCGCCGACTAC
GACGCCGTCCGCGCGCTCGCGGCGGAGGTCACGGCGGCCTCCGGCGCGATGGACGCGGTCCTCAACGTCGCGGGCATCGC
GATCTGGGGGACCGTCTCCGCGATGGAGCACGACCAGTGGCGGCGGCTCGTCGAGGTCAACCTGATGGGTCCGGTCCACG
TGCTCGAGACCCTGGTCCCCGAGATGGTCGACGCCGGCCGCGGCGGGTGGGTCGTCAACGTCTCGTCGGCAGCCGGCATC
ATCGGGATGCCGTGGCACGCCGGCTACAGCGCGACCAAGTTCGGCCTGCGCGGCATCTCCGAGGTGCTCCGCTTCGACCT
CCGCCCGCACGGCATCCACGTCTGCCTGGTCTGCCCGGGCGGCGTCGACACCGGGCTCACCGAGACCGTGCGGATCGCCG
GCGTCGACACCGCGAGCCCCGCCTTCGAGCGCGCGCGGGCCCGGTTCCGTCGGCGCGCGGTGACCCCCGAGGCGGCGGCC
GAGGCGATCGTGCGCGGCATGCTCCGGCGCCGCTACTGGGTCTACACCTCGCTCGACATCCGGCTGGTGCACGCGGTGCA
GCGCTGGTGCCCGCCGGCGTACGCGCTGATGATGACCGTCCTCAACCGCGGCGCGAACCGGGCGCTGCCCGCCGTCGCCC
GCGCCCGGCGCGCGGACCGTGCGGCATGA

Upstream 100 bases:

>100_bases
TCGCGCTGGTGGCCGGTCGGCGCGAGCGGCACGGGCCCCGGATGGCACCGCGGACCCACCTGCCGGCCCGGGTCATCCGG
CGTCGAGGGACGTAACCGCC

Downstream 100 bases:

>100_bases
GCGCCCGCACCACGCCGGCGCGCGTCCGCCCCGGCGGCCTTCGTGAGGTCGGACCGTTCGTGACGGCCTTCGCGTGGCTC
GCGGGCCGGGTCAGCGGCAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MVRRRCTFVRSRPRDLQDANVFVTGAASGIGRATAELLGRQGARLHLTDVDAPRLAEFAEHLRACGSTVVLAVPADIADY
DAVRALAAEVTAASGAMDAVLNVAGIAIWGTVSAMEHDQWRRLVEVNLMGPVHVLETLVPEMVDAGRGGWVVNVSSAAGI
IGMPWHAGYSATKFGLRGISEVLRFDLRPHGIHVCLVCPGGVDTGLTETVRIAGVDTASPAFERARARFRRRAVTPEAAA
EAIVRGMLRRRYWVYTSLDIRLVHAVQRWCPPAYALMMTVLNRGANRALPAVARARRADRAA

Sequences:

>Translated_302_residues
MVRRRCTFVRSRPRDLQDANVFVTGAASGIGRATAELLGRQGARLHLTDVDAPRLAEFAEHLRACGSTVVLAVPADIADY
DAVRALAAEVTAASGAMDAVLNVAGIAIWGTVSAMEHDQWRRLVEVNLMGPVHVLETLVPEMVDAGRGGWVVNVSSAAGI
IGMPWHAGYSATKFGLRGISEVLRFDLRPHGIHVCLVCPGGVDTGLTETVRIAGVDTASPAFERARARFRRRAVTPEAAA
EAIVRGMLRRRYWVYTSLDIRLVHAVQRWCPPAYALMMTVLNRGANRALPAVARARRADRAA
>Mature_302_residues
MVRRRCTFVRSRPRDLQDANVFVTGAASGIGRATAELLGRQGARLHLTDVDAPRLAEFAEHLRACGSTVVLAVPADIADY
DAVRALAAEVTAASGAMDAVLNVAGIAIWGTVSAMEHDQWRRLVEVNLMGPVHVLETLVPEMVDAGRGGWVVNVSSAAGI
IGMPWHAGYSATKFGLRGISEVLRFDLRPHGIHVCLVCPGGVDTGLTETVRIAGVDTASPAFERARARFRRRAVTPEAAA
EAIVRGMLRRRYWVYTSLDIRLVHAVQRWCPPAYALMMTVLNRGANRALPAVARARRADRAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4503817, Length=215, Percent_Identity=29.7674418604651, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=32.48730964467, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI7706318, Length=206, Percent_Identity=33.0097087378641, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI40807363, Length=261, Percent_Identity=26.8199233716475, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI142976729, Length=270, Percent_Identity=24.0740740740741, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4758504, Length=189, Percent_Identity=33.8624338624339, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI223718074, Length=244, Percent_Identity=30.327868852459, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI157739938, Length=248, Percent_Identity=24.5967741935484, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI15277342, Length=208, Percent_Identity=32.2115384615385, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40548397, Length=222, Percent_Identity=29.7297297297297, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI214010158, Length=222, Percent_Identity=29.7297297297297, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI214010156, Length=222, Percent_Identity=29.7297297297297, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI22758144, Length=222, Percent_Identity=29.7297297297297, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI210032110, Length=290, Percent_Identity=23.7931034482759, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI83715985, Length=181, Percent_Identity=33.1491712707182, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=28.9340101522843, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI44680136, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI44680133, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI17738292, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI50726952, Length=194, Percent_Identity=32.9896907216495, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI66933014, Length=209, Percent_Identity=30.1435406698565, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI19743808, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI150247226, Length=218, Percent_Identity=30.2752293577982, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI22507405, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI32455239, Length=199, Percent_Identity=30.6532663316583, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI5031765, Length=199, Percent_Identity=30.6532663316583, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI38424085, Length=235, Percent_Identity=29.7872340425532, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40254992, Length=192, Percent_Identity=29.6875, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI32483357, Length=221, Percent_Identity=26.6968325791855, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=24.4635193133047, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI7705925, Length=190, Percent_Identity=31.0526315789474, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI38348362, Length=186, Percent_Identity=31.1827956989247, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=28.125, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=230, Percent_Identity=30.4347826086957, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786701, Length=198, Percent_Identity=31.8181818181818, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=29.5698924731183, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789057, Length=173, Percent_Identity=28.3236994219653, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790717, Length=195, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787820, Length=241, Percent_Identity=28.6307053941909, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786812, Length=199, Percent_Identity=28.1407035175879, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367365, Length=188, Percent_Identity=30.8510638297872, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789378, Length=224, Percent_Identity=26.3392857142857, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367175, Length=189, Percent_Identity=31.2169312169312, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788459, Length=189, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789208, Length=189, Percent_Identity=24.3386243386243, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=187, Percent_Identity=34.2245989304813, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=200, Percent_Identity=30.5, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=209, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=186, Percent_Identity=27.4193548387097, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=246, Percent_Identity=26.4227642276423, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=187, Percent_Identity=31.5508021390374, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=293, Percent_Identity=24.9146757679181, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=243, Percent_Identity=25.5144032921811, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=226, Percent_Identity=29.646017699115, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=203, Percent_Identity=30.5418719211823, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=194, Percent_Identity=31.9587628865979, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=210, Percent_Identity=30.4761904761905, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=203, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=236, Percent_Identity=25.8474576271186, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=206, Percent_Identity=30.0970873786408, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=194, Percent_Identity=30.9278350515464, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=200, Percent_Identity=31.5, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=194, Percent_Identity=30.4123711340206, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=230, Percent_Identity=27.8260869565217, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=215, Percent_Identity=30.6976744186047, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=197, Percent_Identity=29.4416243654822, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=192, Percent_Identity=29.6875, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=207, Percent_Identity=27.0531400966184, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=209, Percent_Identity=29.6650717703349, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=209, Percent_Identity=29.6650717703349, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=194, Percent_Identity=25.2577319587629, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=198, Percent_Identity=26.2626262626263, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=192, Percent_Identity=26.5625, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320089, Length=238, Percent_Identity=22.6890756302521, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357041, Length=218, Percent_Identity=29.8165137614679, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21356301, Length=269, Percent_Identity=27.1375464684015, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21358495, Length=262, Percent_Identity=25.5725190839695, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17737361, Length=211, Percent_Identity=31.7535545023697, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355631, Length=177, Percent_Identity=27.683615819209, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571526, Length=214, Percent_Identity=28.5046728971963, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24644339, Length=186, Percent_Identity=31.1827956989247, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=197, Percent_Identity=29.9492385786802, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649181, Length=244, Percent_Identity=25.4098360655738, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281364892, Length=178, Percent_Identity=26.4044943820225, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24581726, Length=222, Percent_Identity=26.5765765765766, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639444, Length=191, Percent_Identity=31.9371727748691, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665247, Length=192, Percent_Identity=31.25, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221331216, Length=192, Percent_Identity=31.25, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24665243, Length=191, Percent_Identity=31.413612565445, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331218, Length=191, Percent_Identity=31.413612565445, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643142, Length=185, Percent_Identity=30.8108108108108, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640492, Length=203, Percent_Identity=25.1231527093596, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640442, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32646; Mature: 32646

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRRCTFVRSRPRDLQDANVFVTGAASGIGRATAELLGRQGARLHLTDVDAPRLAEFAE
CCCCHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
HLRACGSTVVLAVPADIADYDAVRALAAEVTAASGAMDAVLNVAGIAIWGTVSAMEHDQW
HHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLVEVNLMGPVHVLETLVPEMVDAGRGGWVVNVSSAAGIIGMPWHAGYSATKFGLRGIS
HHHHHEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHH
EVLRFDLRPHGIHVCLVCPGGVDTGLTETVRIAGVDTASPAFERARARFRRRAVTPEAAA
HHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHH
EAIVRGMLRRRYWVYTSLDIRLVHAVQRWCPPAYALMMTVLNRGANRALPAVARARRADR
HHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
AA
CC
>Mature Secondary Structure
MVRRRCTFVRSRPRDLQDANVFVTGAASGIGRATAELLGRQGARLHLTDVDAPRLAEFAE
CCCCHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
HLRACGSTVVLAVPADIADYDAVRALAAEVTAASGAMDAVLNVAGIAIWGTVSAMEHDQW
HHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLVEVNLMGPVHVLETLVPEMVDAGRGGWVVNVSSAAGIIGMPWHAGYSATKFGLRGIS
HHHHHEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHH
EVLRFDLRPHGIHVCLVCPGGVDTGLTETVRIAGVDTASPAFERARARFRRRAVTPEAAA
HHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHH
EAIVRGMLRRRYWVYTSLDIRLVHAVQRWCPPAYALMMTVLNRGANRALPAVARARRADR
HHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]