BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

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The map label for this gene is fabG [H]

Identifier: 119717038

GI number: 119717038

Start: 2984662

End: 2985591

Strand: Reverse

Name: fabG [H]

Synonym: Noca_2814

Alternate gene names: 119717038

Gene position: 2985591-2984662 (Counterclockwise)

Preceding gene: 119717039

Following gene: 119717037

Centisome position: 59.88

GC content: 74.52

Gene sequence:

>930_bases
GTGACCCCCTCTCTCGACGGCCGGGTGGCGATCGTCACCGGGGCCGGTGCCGGCCTGGGCCGCGCCGAGGCCCTCGCGCT
CGCCGACGCCGGTGCCCGCGTCGTGCTCAACGACCTGCCCGGCGGCGCCGACGAGGCGGCCGAGGAGATCCGGTCCCGCG
GCGGCGAGGCGACGGTCGTCGCCGGCGACGTGGGGGAGCGCGCCAGCGCCGACGCGATGGTCGCCGCGGCCGTCGACGGC
TTCGGCGCCCTGGACATCGTCGTGAACAACGCCGGCGTGACGCGCGACCGGATGCTGTTCAACATGTCCGACGAGGAGTG
GGACCAGGTGATCCACATCCACCTGCGCGGTCACTTCCTGCTGTCCCGCAACGCCGCGGCGTACTGGCGGGCCAAGGCCA
AGGAGACCGGCGCGCCGGTCGGCGCGAGCGTGGTCAACACCGCGTCCGAGGCGTTCCTCTCCGGGCCGCCCGGACAGGCC
AACTACGGCGCTGCGAAGGCCGGGATCGCCGCGCTCACCGTCTCGACCGCGCGGGCGCTGGCCAGCAGCGGCGTGCGCGC
GAACGCGATCTGCCCCCGGGCGCGGACCGCGATGACCGCCGACGTGTTCGGCGCGGACGACTCGGGGCTCGAGGTCGACC
CGTACTCGCCCGAGCACGTCGCGCCCGTCGTCGCCTACCTCTCCTCGCCGGCGGCCGCGCACATCACCGGCCAGGTCTTC
GTCGTGTACGGCGGCATGGTCGCGCTGGTCGCCGCCCCGGTGGTCGAGCAGCGCTTCGACAAGTCCGGCTCGCTGTGGAC
CCTGGACGACCTCGACCGGCAGCTCGGTGGCTACTTCGAGGACCGGGACCCCTCCGTCGGCTTCGCCGCCGACTCGATCA
TGCGCCTCTCGCTGGCCGAGCCCGTCGAGGCCCAGGAGGTGCGGGCATGA

Upstream 100 bases:

>100_bases
TCCAGCTCAAGACCGACCAGACCACGCCGGAGAACATCGACGCCGTCAAGCGGGCGGTGGCCGCCTGCCCGCGCGCCGCG
CTCTCCCTGGAGGACTGAGC

Downstream 100 bases:

>100_bases
ACCGGCTGCAGGGGAAGGTCGCGATCGTGACCGGCGGTGCGCAGGGCCAGGGGGCCGGCATCAGCCGCGCCTTCGTGGCC
GAGGGCGCCCGCGTGGTGAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTPSLDGRVAIVTGAGAGLGRAEALALADAGARVVLNDLPGGADEAAEEIRSRGGEATVVAGDVGERASADAMVAAAVDG
FGALDIVVNNAGVTRDRMLFNMSDEEWDQVIHIHLRGHFLLSRNAAAYWRAKAKETGAPVGASVVNTASEAFLSGPPGQA
NYGAAKAGIAALTVSTARALASSGVRANAICPRARTAMTADVFGADDSGLEVDPYSPEHVAPVVAYLSSPAAAHITGQVF
VVYGGMVALVAAPVVEQRFDKSGSLWTLDDLDRQLGGYFEDRDPSVGFAADSIMRLSLAEPVEAQEVRA

Sequences:

>Translated_309_residues
MTPSLDGRVAIVTGAGAGLGRAEALALADAGARVVLNDLPGGADEAAEEIRSRGGEATVVAGDVGERASADAMVAAAVDG
FGALDIVVNNAGVTRDRMLFNMSDEEWDQVIHIHLRGHFLLSRNAAAYWRAKAKETGAPVGASVVNTASEAFLSGPPGQA
NYGAAKAGIAALTVSTARALASSGVRANAICPRARTAMTADVFGADDSGLEVDPYSPEHVAPVVAYLSSPAAAHITGQVF
VVYGGMVALVAAPVVEQRFDKSGSLWTLDDLDRQLGGYFEDRDPSVGFAADSIMRLSLAEPVEAQEVRA
>Mature_308_residues
TPSLDGRVAIVTGAGAGLGRAEALALADAGARVVLNDLPGGADEAAEEIRSRGGEATVVAGDVGERASADAMVAAAVDGF
GALDIVVNNAGVTRDRMLFNMSDEEWDQVIHIHLRGHFLLSRNAAAYWRAKAKETGAPVGASVVNTASEAFLSGPPGQAN
YGAAKAGIAALTVSTARALASSGVRANAICPRARTAMTADVFGADDSGLEVDPYSPEHVAPVVAYLSSPAAAHITGQVFV
VYGGMVALVAAPVVEQRFDKSGSLWTLDDLDRQLGGYFEDRDPSVGFAADSIMRLSLAEPVEAQEVRA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=253, Percent_Identity=41.501976284585, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=35.2941176470588, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=29.9610894941634, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI4758504, Length=195, Percent_Identity=33.8461538461538, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI31542939, Length=230, Percent_Identity=32.6086956521739, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI83715985, Length=188, Percent_Identity=33.5106382978723, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=28.6852589641434, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=29.8387096774194, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=26.4822134387352, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI224922801, Length=178, Percent_Identity=33.1460674157303, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=25, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI40254986, Length=209, Percent_Identity=28.2296650717703, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=35.0597609561753, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=32.4324324324324, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=29.6153846153846, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=27.4509803921569, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=29.0836653386454, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=29.5719844357977, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=29.1338582677165, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=25.968992248062, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=31.2, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=28.4046692607004, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789057, Length=265, Percent_Identity=25.2830188679245, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=250, Percent_Identity=36, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=34.5238095238095, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=33.0769230769231, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=32.9317269076305, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=27.8985507246377, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=197, Percent_Identity=36.5482233502538, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=28.3524904214559, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=28.7822878228782, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=28.90625, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=273, Percent_Identity=26.3736263736264, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=26.5682656826568, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=29.4776119402985, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982365, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=27.4611398963731, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=30.4511278195489, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=26.9662921348315, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=26.7657992565056, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=26.8115942028986, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=256, Percent_Identity=25.78125, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=253, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=28.1481481481481, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=27.6363636363636, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=26.5384615384615, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=202, Percent_Identity=26.7326732673267, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=26.7657992565056, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=27.4436090225564, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=287, Percent_Identity=25.7839721254355, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=221, Percent_Identity=31.2217194570136, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=302, Percent_Identity=30.1324503311258, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=34.7826086956522, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=30.46875, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI18859837, Length=233, Percent_Identity=37.7682403433476, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=36.1111111111111, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17737361, Length=191, Percent_Identity=37.17277486911, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=32.2834645669291, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=28.2945736434109, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357673, Length=257, Percent_Identity=30.3501945525292, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=28.3464566929134, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357041, Length=196, Percent_Identity=30.6122448979592, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=27.7566539923954, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 31762; Mature: 31631

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSLDGRVAIVTGAGAGLGRAEALALADAGARVVLNDLPGGADEAAEEIRSRGGEATVV
CCCCCCCCEEEEEECCCCCCHHHEEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCEEEE
AGDVGERASADAMVAAAVDGFGALDIVVNNAGVTRDRMLFNMSDEEWDQVIHIHLRGHFL
ECCCCCCCCCCCEEEEHHCCCCEEEEEEECCCCCHHHEEECCCCHHHCEEEEEEEEEEEE
LSRNAAAYWRAKAKETGAPVGASVVNTASEAFLSGPPGQANYGAAKAGIAALTVSTARAL
EECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHH
ASSGVRANAICPRARTAMTADVFGADDSGLEVDPYSPEHVAPVVAYLSSPAAAHITGQVF
HHCCCCCCCCCCCHHHHEEEEEECCCCCCCEECCCCCHHHHHHHHHHCCCCCEEECCEEE
VVYGGMVALVAAPVVEQRFDKSGSLWTLDDLDRQLGGYFEDRDPSVGFAADSIMRLSLAE
EEECHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHEECCCC
PVEAQEVRA
CCCHHHCCC
>Mature Secondary Structure 
TPSLDGRVAIVTGAGAGLGRAEALALADAGARVVLNDLPGGADEAAEEIRSRGGEATVV
CCCCCCCEEEEEECCCCCCHHHEEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCEEEE
AGDVGERASADAMVAAAVDGFGALDIVVNNAGVTRDRMLFNMSDEEWDQVIHIHLRGHFL
ECCCCCCCCCCCEEEEHHCCCCEEEEEEECCCCCHHHEEECCCCHHHCEEEEEEEEEEEE
LSRNAAAYWRAKAKETGAPVGASVVNTASEAFLSGPPGQANYGAAKAGIAALTVSTARAL
EECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHH
ASSGVRANAICPRARTAMTADVFGADDSGLEVDPYSPEHVAPVVAYLSSPAAAHITGQVF
HHCCCCCCCCCCCHHHHEEEEEECCCCCCCEECCCCCHHHHHHHHHHCCCCCEEECCEEE
VVYGGMVALVAAPVVEQRFDKSGSLWTLDDLDRQLGGYFEDRDPSVGFAADSIMRLSLAE
EEECHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHEECCCC
PVEAQEVRA
CCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]