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The map label for this gene is pgsA1 [H]

Identifier: 119716943

GI number: 119716943

Start: 2889994

End: 2890596

Strand: Reverse

Name: pgsA1 [H]

Synonym: Noca_2718

Alternate gene names: 119716943

Gene position: 2890596-2889994 (Counterclockwise)

Preceding gene: 119716944

Following gene: 119716942

Centisome position: 57.98

GC content: 72.47

Gene sequence:

>603_bases
GTGGCGGACGACTCGACGCGCAACCGCGTGTGGACGCTTCCCAACCTGCTCAGCATGATCCGGCTGGCGGGCGTCCCGGT
CTTCCTCTGGCTGGTGCTGGGCCCGGAGGCGGACGGCTGGGCACTGGCGCTGCTGGCGGTCTCCGGCATCACCGACTTCC
TCGACGGCTACCTCGCGCGCCGGCTGGGGCAGACCTCGACGCTGGGCCAGGTGCTGGACCCGGTCGCCGACCGGCTCTAC
ATCCTGGCCGTCGTCGTGGGCCTCGCGCTGCGCGACGTGATCCCCTGGTGGGCGGCGCTCTCGCTGCCGCTGCGCGACCT
CCTGCTCTGGGGGCTGGTGCCGCTGCTGCGGACCCGTGGCTACAGCGCGCTGCCGGTGCACTTCCTGGGCAAGGCCGCGA
CCTTCAACCTGCTCTACGCCTTCCCGCTGCTGCTGCTCGGTGACGGCGACGGGACGGTCGCGACCCTCGCGAACGTGTTC
GGCTGGGCGTTCGCCCTGTGGGGGATCGGGCTCTACTGGTGGGCCGGCATCCTCTACGCCTGGCAGGTGCGCACCCTGCT
GGCCACCACCGAGAGGCGGACGGCGGCGGTCCCCGATGCCTGA

Upstream 100 bases:

>100_bases
TGGAGGACCACCTCTGACCGGGAGCGGCTGCCACCGATCCGGGGTCCCGGCCGATAGGCTTGGCGCGGCAGCACACCCCG
GGAGAGCAGACAGGCGAGCA

Downstream 100 bases:

>100_bases
CTCCCGGACCACGACGGCCGACCGGGTCAGCACGCCGCTGCTGACGCTGATCACCCAGCAGTCCCTCGACGAGGACTACC
GCCACGTCGCGGAGCGCCGC

Product: CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MADDSTRNRVWTLPNLLSMIRLAGVPVFLWLVLGPEADGWALALLAVSGITDFLDGYLARRLGQTSTLGQVLDPVADRLY
ILAVVVGLALRDVIPWWAALSLPLRDLLLWGLVPLLRTRGYSALPVHFLGKAATFNLLYAFPLLLLGDGDGTVATLANVF
GWAFALWGIGLYWWAGILYAWQVRTLLATTERRTAAVPDA

Sequences:

>Translated_200_residues
MADDSTRNRVWTLPNLLSMIRLAGVPVFLWLVLGPEADGWALALLAVSGITDFLDGYLARRLGQTSTLGQVLDPVADRLY
ILAVVVGLALRDVIPWWAALSLPLRDLLLWGLVPLLRTRGYSALPVHFLGKAATFNLLYAFPLLLLGDGDGTVATLANVF
GWAFALWGIGLYWWAGILYAWQVRTLLATTERRTAAVPDA
>Mature_199_residues
ADDSTRNRVWTLPNLLSMIRLAGVPVFLWLVLGPEADGWALALLAVSGITDFLDGYLARRLGQTSTLGQVLDPVADRLYI
LAVVVGLALRDVIPWWAALSLPLRDLLLWGLVPLLRTRGYSALPVHFLGKAATFNLLYAFPLLLLGDGDGTVATLANVFG
WAFALWGIGLYWWAGILYAWQVRTLLATTERRTAAVPDA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=110, Percent_Identity=40, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI10092647, Length=131, Percent_Identity=38.9312977099237, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71984838, Length=110, Percent_Identity=37.2727272727273, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71984834, Length=110, Percent_Identity=37.2727272727273, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320059, Length=130, Percent_Identity=33.0769230769231, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650130, Length=122, Percent_Identity=34.4262295081967, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24650126, Length=122, Percent_Identity=34.4262295081967, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24650128, Length=122, Percent_Identity=34.4262295081967, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21914; Mature: 21783

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDSTRNRVWTLPNLLSMIRLAGVPVFLWLVLGPEADGWALALLAVSGITDFLDGYLAR
CCCCCCCCEEECHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RLGQTSTLGQVLDPVADRLYILAVVVGLALRDVIPWWAALSLPLRDLLLWGLVPLLRTRG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
YSALPVHFLGKAATFNLLYAFPLLLLGDGDGTVATLANVFGWAFALWGIGLYWWAGILYA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQVRTLLATTERRTAAVPDA
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADDSTRNRVWTLPNLLSMIRLAGVPVFLWLVLGPEADGWALALLAVSGITDFLDGYLAR
CCCCCCCEEECHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RLGQTSTLGQVLDPVADRLYILAVVVGLALRDVIPWWAALSLPLRDLLLWGLVPLLRTRG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
YSALPVHFLGKAATFNLLYAFPLLLLGDGDGTVATLANVFGWAFALWGIGLYWWAGILYA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQVRTLLATTERRTAAVPDA
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]